IIrbs
Iqela lezonyango eliSebenzayo leKlinikhi yeHerbs. Iyeza elilungiswe kwizityalo, kuquka uninzi lwamayeza esintu ehlabathi okunyanga izifo. Uninzi lucinga ngamayeza esintu njengeemveliso ezithengiswa phezu kwekhawuntara njenge "zongezo," ezifana nesicatshulwa se-palmetto okanye i-ointment. Nangona kunjalo, amayeza amaninzi athengiswayo kunye namayeza kagqirha asekelwe kwizithako ezivela kwizityalo, kuquka i-aspirin kunye ne-digoxin. Uvavanyo lwaseLebhu lubonisa ukuba amanye amayeza esintu ayasebenza ekuguleni. Umntu ngamnye kufuneka asebenzise la mayeza ngononophelo njengamayeza achazwe ngugqirha, esebenzisa isilumkiso ukuphepha ukugqithisa, ukusebenzisana namanye amayeza, kunye nokusetyenziswa kakubi.
Amayeza esintu lunye uhlobo lwezongezo zokutya. Zithengiswa njengeepilisi, iipilisi, iipilisi, iti, izicatshulwa, kunye nezityalo ezitsha okanye ezomisiweyo. Abantu basebenzisa amayeza esintu ukugcina okanye ukuphucula impilo. Abaninzi bakholelwa ukuba iimveliso ezibhalwe "zendalo" zikhuselekile ukusebenzisa. Oku akuyonyani, njengoko amayeza esintu enganyanzelekanga ukuba aye kuvavanyo olwenziwa ngamachiza. Ezinye imifuno, njenge-comfrey kunye ne-ephedra, zinokubangela ingozi enkulu. Ukongeza, ukusebenzisana kwamayeza athile amayeza kagqirha okanye aphuma ekhawuntareni kunokusebenza kakuhle namanye amayeza kwaye kube yingozi. Ngaphambi kokuba usebenzise amayeza esintu, qala, fumana ulwazi kwimithombo ethembekileyo kwaye uxelele umboneleli wakho wezempilo malunga nawo nawaphi na amayeza esintu owathathayo.
by UGqr Alex Jimenez LweMpilo , I-Gastro Health Intestinal , I-Gut ne-Intestinal Health , impilo , IIrbs , isondlo , Ukuphila
Ngaba uziva:
Ubuhlungu, isisa, ukuqaqamba kwicala lasekhohlo? Iintlungu zesisu, ukutsha, okanye ukrakra, iiyure eziyi-1-4 emva kokutya? Iingxaki zokutya zizalisa ukuphumla kunye nokuphumla? Ukuqunjelwa okungafunekiyo esiswini? Ingqondo ngokubanzi yokuqhakaza?
Ukuba ufumana naziphi na kwezi meko, ke into isenokuba yinto engalunganga emzimbeni wakho, ngakumbi esiswini. Kutheni ungazami ukongeza i-thyme kukutya kwakho.
Thyme
Kwilizwe eliphambili, i-thyme ihlala idityaniswa nezitya ezinesonka esincoma incasa. Lo mthi unamagqabi unokudityaniswa nenkukhu kwaye unokunika izitya zokutya njengokugalela izinto, iisosi, izityu kunye nesobho ezonyukayo kwisebe lencasa. Nangona I-thyme yintsholongwane ebukekayo Kuyamangalisa ukuba, kukho enye imbali ngale imifuno inamagqabi ayinguye wonke umntu owaziyo okwangoku. Imbali ibonisa ukuba i-thyme yayisetyenziswa njengesiqholo ngama-Egypt amandulo, ngelixa iGrisi yakudala yayisebenzisa i-thyme njengempepho kwiitempile zabo. Imbali ide yabonisa ukuba i-thyme inevumba “elicocekileyo” elincede abantu ukuba baphuphe amaphupha amabi kwi-Middle Ages. Kwihlabathi lanamhlanje, i-thyme yaziwa kakhulu ngokuba nako ukuphucula iincasa kwilizwe lokupheka. Nangona kunjalo, iyaziwa nangakumbi ngamayeza ayo okucoca amayeza asebenzayo.
Izifundo zifumene ukuba malunga ne-1/3 yabo bonke abantu ababeswelekile emhlabeni ngenxa yezifo ezosulelayo. Ngokwahlukileyo koko, inani elothusayo lezinto ezincinci ziye zaxhathisa kunyango lwentsholongwane. Kuyamangalisa, nangona kunjalo, izazinzulu zizama ukufumana iindlela zokujonga ezinye iindlela zonyango ezichasene ne-thyme. Kuba izityalo zinomatshini wokhuselo lwendalo owakhiwe ngaphakathi kubo kuba bayakwazi ukuzikhusela kwiimeko ezimbi zemo engqongileyo. Ke, ngokuba i-thyme iyimifuno yeMeditera, iipropathi zayo zezempilo ziluncedo emzimbeni kwaye zinokuthoba isiphumo seentsholongwane eziyingozi.
Izixhobo ezifanelekileyo
Ezinye zeepropati eziyinzuzo ekufuneka zinikezelwe yi-thyme ziyamangalisa kuba zisetyenziselwe amayeza I-Thyme inodidi lwendalo oluvela ngokwenzeka kwiicomputer ezaziwa ngokuba zii-biocides. Izifundo zibonisa ukuba ezi zinto zihlanganisiweyo ziyaziwa ukutshabalalisa naziphi na izinto eziyingozi ezinjengebhaktiriya ezosulelayo, ngelixa zikwanazo iipropathi ezinamandla zokubulala iintsholongwane. In Isifundo sophando ngo-2010 , iphakamise ukuba i-thyme inokunciphisa ukungqubana kwamagciwane kwezinye iziyobisi eziqhelekileyo, kubandakanya i-penicillin. Ezinye izinto ezincedo eziboniswa yi-thyme zibandakanya:
Ifuthe legazi
I-Thyme ifunyenwe ukunceda ukunciphisa uxinzelelo lwegazi oluphezulu kubantu. Abaphandi eSerbia bafumanisile i-thyme yasendle inokunciphisa uxinzelelo lwegazi lomntu ngezifundo zezilwanyana. Ikwabonise nokuba iimpuku zifana njani nabantu xa bejongana noxinzelelo lwegazi emzimbeni. Ngelixa esinye isifundo safumanisa Ukukhupha i-thyme kunokunciphisa izinga lokuphakama kwentliziyo ngelixa kunciphisa i-cholesterol embi. Olu phando luye lwabonisa ukuba i-thyme yayikade isetyenziselwa ukunyanga izifo ezahlukeneyo ezinokwenzakalisa umzimba kunyango lwesintu. Kuyenzeka ukuba i-thyme isetyenziswe njengendawo yokufaka ityuwa ekutyeni.
Thintela usulelo lwangaphakathi
Izifundo zifumene I-thyme iyakwazi ukwenza i-bacterium ethile yangaphakathi ukuba idityaniswe nezifo zamathumbu. Kwi Ucwaningo lwe-2017 , izazinzulu zifumanise ukuba xa izifundo sele zidibene neClostridium perfringens, intsholongwane eyingozi enokwenzakalisa amathumbu, inokunyangwa nge-thyme. Isiphumo sibonisa ukuba izifundo zazinosulelo oluncinci lweebacteria emathunjini abo ngelixa zinezilonda ezimbalwa kunye nokumbalwa kokusweleka okuhambelana ne-C.
Yongeza inkqubo ye-immune
Nokuba wonke umntu unokuzama ukuphila ngendlela esempilweni, ngamanye amaxesha kunzima ukufumana zonke iivithamini ekufuneka umzimba uzilondoloze ngaphakathi nangaphandle. Uphando lu bonise ukuba i-thyme inokubonelela ngomthamo osempilweni weevithamini C no-A. Nanini na ngeli xesha libandayo okanye umkhuhlane, i-thyme inokuba luncedo kuye nabani na ofuna ukuthintela ukubanda okanye umkhuhlane ukuba ungenzeki okanye ungatyisi mpawu iimpawu. Enye yezinto ezinokuba luncedo i-thyme inokuzenzela amajoni omzimba kukuba ingangumthombo olungileyo wezimbiwa ezifana nobhedu, ifayibha, isinyithi kunye ne-manganese ekufuneka umzimba ukuze usebenze ngokufanelekileyo.
Iipropathi zeAntimicrobial kunye neAntifungal
I-Thyme ineempawu ze-antimicrobial kunye ne-antifungal eziyinzuzo emzimbeni. Isifundo sePortugal sifumene ukuba i-thyme inokubonelela ngepropathi yokulwa nomhlaza kubantu abanomhlaza wekolon. Olu phando luye lwabonisa ukuba imichiza ye-thyme's inokuchonga imisebenzi yomhlaza we-colon kunye nokunciphisa inkqubo yayo ukuba ibe mandundu. Olunye uphando olufunyenwe eTurkey lubonakalisile ukuba i-thyme yasendle inokuba nefuthe elihle kwimisebenzi yomhlaza webele. Olu phando lufumanise ukuba i-thyme ekhutshwayo inokusetyenziswa kumachiza onyango amayeza onyango.
Kwipropathi ye-antifungal, izifundo zifumanise ukuba i-thyme inokuba luncedo ekulweni neentsholongwane zokungunda emzimbeni njengosuleleko lwe-yeast. Baphengululi eItali I-fungus Candic albicans iqhele ukubanga usulelo lwe-yeast emlonyeni kunye nasekhaya lobufazi. Olunye uphononongo olufunyenweyo ukuba i-thyme ye-oyile eyimfuneko inokuphucula ukutshatyalaliswa kwe-Albicans emzimbeni kunye nokuthintela isikhunta ukuba singasasazeki. Iziphumo zabonisa ukuba umngxunya wokungunda unemveliso ye-biofilm, kwaye yi-oyile ye-thyme kuphela ekuyeyona oyile yeyona inhibitory echaphazela ukuveliswa kwe-biofilm kwimingxunya yokutya.
isiphelo
TNazi iipropathi ezininzi eziluncedo ukuba i-thyme inokuba nakho ukunceda kungekuphela nje komzimba kodwa kunye nokukhuselwa komzimba kunye nenkqubo yamathumbu. Kuyamangalisa ngokwenene ukuba le imifuno inokuba neempembelelo zokucoca emzimbeni kunye nokuphucula incasa yezitya zokutya. Ekubeni abantu abaninzi besebenzisa i-thyme kwizitya zabo zokupheka, akumangalisi ukuba i-thyme yimifuno yomlingo ngokwenene, enokunceda umzimba ufezekise ingqondo yempilo kunye nokuphila kakuhle. Abanye iimveliso inokuba yingenelo emzimbeni, kubandakanya amajoni omzimba, ngokubonelela ngenkxaso kumathumbu ngokuzinza okukhulu, i-bioavailability, kunye nentuthuzelo yokugaya ukutya.
Ubungakanani bolwazi lwethu lukhawulelwe kwi-chiropractic, musculoskeletal, kunye nemicimbi yezempilo yovalo okanye amanqaku amayeza asebenzayo, izihloko kunye neengxoxo. Sisebenzisa iiprothokholi zempilo ezisebenzayo ukunyanga ukwenzakala okanye ukuphazamiseka kwenkqubo yemusculoskeletal. Iofisi yethu yenze umzamo oqinisekileyo wokubonelela ngezikhokelo ezixhasayo kwaye ichonge isifundo sophononongo esifanelekileyo okanye izifundo ezixhasa izithuba zethu. Sikwenza iikopi zezifundo zophando ezixhasayo ziya kufumaneka ebhodini okanye kuluntu xa luceliwe. Ukuqhubeka nokuxoxa ngomxholo ongentla, nceda ukhululeke ukubuza uGqirha Alex Jimenez okanye unxibelelane nathi apha 915-850-0900 .
Iingxelo:
Iilebhu, uPhando lweOncology yoNyango. Iziphumo ze-Thymus Serpyllum Extract kwi-Cell Proliferation, i-Apoptosis kunye ne-Epigenetic Events kwiiseli zomhlaza webele. UTaylor noFrancis , 19 Novemba 2012, www.tandfonline.com/doi/full/10.1080/01635581.2012.719658#.Ul_MYWTk-z5.
Iqela, iMfundo yeBhayoloji. HyThyme yezempilo yamathumbu IBhlog yoPhando ngeebhayoloji I-2017, blog.bioticresearch.com/thyme-for-gut-health.
IAlamgeer, okqhubekayo. UVavanyo lwePharmacological lweMpembelelo yokuchasana neepesenti zoMoya weTymus Linearis Benth. I-Acta Poloniae Pharmaceutica , I-US National Library of Medicine, i-2014, www.ncbi.nlm.nih.gov/pubmed/25272894.
Unothando, Ihlobo. 9 Izibonelelo zezeMpilo zeThyme LwezeMpilo , Nge-5 Meyi, 2016, www.healthline.com/health/health-benefits-of-thyme.
UFelman, uAdam. Zithini izibonelelo zeThyme? MedicalNewsToday , Nge-23 ka-Agasti ka-2018, www.medicalnewstoday.com/articles/266016.
UGordo, uJoana, et al. HI-Thymus Mastichina: Amachiza eKhemikhali kunye nomsebenzi wabo wokuLwa noMhlaza YoNxibelelwano lweMveliso , I-US National Library of Medicine, ngoNovemba 2012, www.ncbi.nlm.nih.gov/pubmed/23285814.
UKhan, uMohd SA, et al. I-Sub-MICs zeCarum Copticum kunye neThymus Vulgaris Impembelelo yeZinto eziShukumayo kunye noQeqesho lweBiofilm kwiCandida Spp. IBMC yokuGqibezela kunye neNyango elingelinye , Kwi-BioMed Central, nge-15 kaSeptemba ngo-2014, www.ncbi.nlm.nih.gov/pubmed/25220750.
UKim, uGil-Hah, et al. Ukwenziwa kweKhemikhali, iNtshukumo yeLarvicidal, kunye nokuThintela abantu abadala kuTymus Magnus ngokuchasene neAedes Albopictus. Ijenali yoMbutho oLawula iMiyane eMelika , Umbutho woLawulo lweMiyane eMelika, nge-1 kaSeptemba ngo-2012, www.bioone.org/doi/abs/10.2987/12-6250R.1.
IPalaniappan, uKavitha, kunye noRichard A. Holley. SeUkusetyenziswa kwee-Antimicrobial zendalo ukonyusa ukuSoleka kweAntibiotic yeBacteria eXhathisa iziyobisi. Ijenali yaMazwe ngaMazwe yokutya kweMicrobiology , Elsevier, 13 Epreli 2010, www.sciencedirect.com/science/article/pii/S0168160510001868.
Iqela, i-WHO. Oonobangela abalishumi abaphambili bokufa World Health Organization , Umbutho wezeMpilo weHlabathi, nge-24 kaMeyi 2018, www.who.int/mediacentre/factsheets/fs310/en/.
Wong, uCathy. UseUkusetyenziswa kwe-Thyme kwiNyango eNye Impilo entle kakhulu , Impilo kakhulu, 28 Epreli 2020, www.verywellhealth.com/the-benefits-of-thymus-vulgaris-88803.
I-Yin, D., iDu, uE, uYuan, uJokqhubekayo. I-thymol eyongezelelweyo kunye ne-carvacrol yonyusa ileum Lactobacillus Inani labemi kunye nokunciphisa ukusebenza kwe-necrotic enteritis ebangelwa ngu-I-Clostridium perfringes KwinkukhuSci Rep 7, 7334 (2017). doi.org/10.1038/s41598-017-07420-4
IYunivesithi ibonelela ngeendlela ezahlukeneyo zobungcali bobuchwephesha bokusebenza kunye nokudibanisa amayeza. Injongo yabo kukwazisa abantu abafuna ukwenza umahluko kwiinkalo zonyango ezisebenzayo ngolwazi abanokulunikezela.
VIDEO
by UGqr Alex Jimenez LweMpilo , impilo , Heart Health , IIrbs , isondlo , nezongezo , Ukuphila
Ngaba uziva:
Isiyezi xa usukuma ngokukhawuleza? Ukuqala kancinci? Edema kunye nokudumba emaqatheni nasezandleni? Ukunyibilika kwemisipha? Ngaba udiniwe okanye uvila?
Ukuba ufumana naziphi na kwezi meko, kunokubakho ukungasebenzi kakuhle kwinkqubo yomzimba wakho, kubandakanya amajoni omzimba. Kutheni ungazami imifuno yaseTshayina, i-astragalus ukunceda ukunciphisa iimpawu.
Astragalus
Kwimichiza yesiTshayina yesiqhelo, i-herb astragalus isetyenziselwe amawaka eminyaka kwaye yaziwa ukomeleza i-chi okanye i-qi amandla obomi emzimbeni. Oku herb yaziwa ukuba uqashwe rhoqo kwiimeko ezinxulumene nobuthathaka ngokubanzi emzimbeni njengokukhathala, isifo sokuqaqamba kwamalungu omzimba, ukungabi namdla wokutya, izifo zentliziyo, kunye nezinye iimeko ezinokwenza buthathaka emzimbeni. Kuyamangalisa, nangona kunjalo, i-astragalus ingasetyenziselwa ukwenza impilo yezintso kwaye, ngokudityaniswa kwe-ginseng kunye ne-echinacea, inokunyusa amajoni omzimba. Kukho iintlobo ngeentlobo zeeastragalus eziyinzalelwane yasempuma-mpuma yeAsia, kwaye iingcambu zayo zifuna ukuba zome kwaye zifakwe kumgubo ukuze ziguqulwe ukuze zichithwe njenge-capsule okanye njengeti.
IiPropathi eziXhamlayo ze-Astragalus
Izifundo zifumene ukuba isiphumo se-astragalus's pharmacological sinokuqulatha izinto ze-phytochemical, ezibandakanya uninzi lwe-saponins polysaccharides kunye ne-flavonoids ekufuneka amajoni omzimba asebenze ngokuchanekileyo. Olunye uphononongo olufunyenweyo ukuba i-astragalus iqulethe malunga namashumi amabini eetreyini zokutsala abaluleke kakhulu emzimbeni. Ukukhupha i-astragalus, ineepropati zokuguqula amandla omzimba kwi-vivo kunye ne-vitro kwizilwanyana nakubantu, kwaye uphando lubonisa ukuba i-herb ivuselela kwaye inefuthe kwi-cytokines yokuphendula amajoni omzimba ngelixa ishiya ii-cytokines ezosulelekileyo zingachaphazeleki.
Ezinye zeepropathi eziyinzuzo ukuba i-astragalus enokuba nayo emzimbeni isaphandwa; nangona kunjalo, le herb yesiTshayina inokunceda umzimba ukuba usebenze ngokuchanekileyo kwaye usebenze.
Ukuphuculwa kwenkqubo yokugonya
Uphononongo lubonise ukuba i-astragalus iqulethe ezinye iikhompawundi zesityalo eziyinzuzo ezinokuphucula amajoni omzimba. Izifundo zibonakalisa ukuba eyona ndima iphambili yomzimba yokuzikhusela kukuba inceda ukukhusela umzimba kwizifo zangaphandle ezifana neebacteria eziyingozi kunye neentsholongwane ezinokubangela umntu agule. Uphando lufumanisile ukuba bukhona ubungqina bokuba i-astragalus inokunyusa ukuveliswa komzimba kweeseli ezimhlophe zegazi, eziya kuthi zincede ukuthintela izifo ukuba zingene emzimbeni. Kwi nezinye izifundo zophando , kufunyenwe ukuba ingcambu ye-astragalus yaziwa ukunceda umzimba bulala iintsholongwane kunye neentsholongwane ezibangelwa lusulelo. Nangona uphando lusenokulinganiselwa, zikhona Izifundo ezibonisa ukuba i-astragalus iyakwazi ukulwa nokusulelwa yintsholongwane efana nokubanda okuqhelekileyo kunye nosulelo lwesibindi emzimbeni womntu.
Ukuphucula ukuSebenza kweentliziyo
Uphando lubonisa ukuze i-astragalus ikwazi ukuphucula ukusebenza kwentliziyo ngokwandisa imithambo yegazi kwaye yandise inani legazi elimpompa liphuma entliziyweni. Kwisifundo sophando lwezonyango , ibonakalise ukuba abaguli banikwe ubuncinci i-2.25 gram ye-astragalus kwiiveki ezimbini kwaye babone ukuphucuka okubonakalayo ekusebenzeni kwentliziyo yabo. Kwesinye isifundo , ikwabonisa ukuba i-astragalus inokunceda ukunciphisa iimpawu ze-myocarditis, imeko yokosuleleka entliziyweni.
Ukuphucula ukuSebenza kweentso
I-Astragalus inokunceda ukuxhasa impilo yezintso emzimbeni ngokuphucula ukuhamba kwegazi ukuya ezintso kunye nokulinganisa iproteni kumchamo. Uphononongo lubonakalisile ukuba iproteinuria ikwimeko apho kukho inani elingaqhelekanga leprotheni efumaneka kumchamo, kwaye kunokuba luphawu lokuba izintso azisebenzi ngokuqhelekileyo okanye zinokwenzakala. Okumangalisayo kukuba, zazikho esinye isifundo esibonisiweyo ukuba i-astragalus inokuphucula iimpawu ze-proteinuria kubantu abanesifo sezintso. Izifundo sele zifumene ukuba i-astragalus inokunceda ukukhusela ukosuleleka nakubani na onomsebenzi wokunciphisa izintso kunye nokunciphisa umngcipheko wokuphazamiseka kwezintso okwaziwa njenge-nephrotic syndrome.
isiphelo
I-Astragalus yinto ekhethekileyo yemifuno enokunceda amajoni omzimba ukuba asebenze ngokuchanekileyo. Nangona kukho inani elilinganiselweyo lophando kule-herb, kodwa iipropathi eziyinzuzo ezibonelela ngayo emzimbeni ziyamangalisa ngokwenene. I-Astragalus inokutyiwa ziicaphule okanye iveliswe njengeti, ukuze ngaloo ndlela, abantu banokonwabela iipropathi eziyinzuzo kwaye imizimba yabo isebenza ngokugqwesileyo empilweni nasempilweni. Abanye iimveliso inika inkxaso kumandla omzimba kwaye uncede ekujongeni i-amino acid enzelwe ukuxhasa amathumbu ngelixa unika inkxaso enkulu kwinkqubo ye-metabolic.
Ubungakanani bolwazi lwethu lukhawulelwe kwi-chiropractic, musculoskeletal, kunye nemicimbi yezempilo yovalo okanye amanqaku amayeza asebenzayo, izihloko kunye neengxoxo. Sisebenzisa iiprothokholi zempilo ezisebenzayo ukunyanga ukwenzakala okanye ukuphazamiseka kwenkqubo yemusculoskeletal. Iofisi yethu yenze umzamo oqinisekileyo wokubonelela ngezikhokelo ezixhasayo kwaye ichonge isifundo sophononongo esifanelekileyo okanye izifundo ezixhasa izithuba zethu. Sikwenza iikopi zezifundo zophando ezixhasayo ziya kufumaneka ebhodini okanye kuluntu xa luceliwe. Ukuqhubeka nokuxoxa ngomxholo ongentla, nceda ukhululeke ukubuza uGqirha Alex Jimenez okanye unxibelelane nathi apha 915-850-0900 .
Iingxelo:
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UPeng, TQ, et al. Impembelelo kunye noMatshini weAstragalus Membranaceus kwiCoxsackie B3 Virus RNA kwiimpuku. UZhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Ijenali yeTshayina yoNyango oluManyeneyo kunye neNtshona , I-US National Library of Medicine, ngoNovemba 1994, www.ncbi.nlm.nih.gov/pubmed/7703635.
I-Piao, i-Yuan-lin, kunye ne-Xiao-chun Liang. Inaliti yeAstragalus Membranaceus edityaniswe nonyango oluqhelekileyo lweMiyocarditis yentsholongwane: uphononongo olucwangcisiweyo lweemvavanyo ezilawulwa ngokungahleliwe Ijenali yaseTshayina yeMayeza aDibeneyo , I-US National Library of Medical, Oct. 2014, www.ncbi.nlm.nih.gov/pubmed/25098261.
Iqela, iDFH. Astragalus: Igama elihlekisayo Iziphumo eziBalulekileyo Uyilo lwezeMpilo I-9 Oct. 2018, blog.designsforhealth.com/astragalus-funny-name-sential-result.
Iqela, iNCBI. IAstragalus Membranaceus. Monograph ograph Ukuphononongwa kwakhona ngoNyango: Ijenali yeNyango yoNyango , I-US National Library of Medicine, ngoFebruwari 2003, www.ncbi.nlm.nih.gov/pubmed/12611564.
UWang, uDeqing, et al. Isifundo seZiphumo zeTotal Flavonoids zeAstragalus kuQeqesho lweAtherosclerosis kunye neendlela ezinokubakho. Unyango lwe-Oxidative kunye nokuPhila ixesha elide , I-Hindawi Publishing Corporation, 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3306992/.
Wu, Hong Mei, okqhubekayo. Ungenelelo lokuThintela usulelo kwiNephrotic Syndrome I-Cochrane Database yeeNkqubo eziPhononongo , UJohn Wiley kunye noonyana, Ltd, 18 Epreli 2012, www.ncbi.nlm.nih.gov/pubmed/22513919.
Yang, Qing-wena, et al. Iziphumo ze-Astragalus kwiCardiac Function kunye neSerum Tumor Necrosis Factor-Alpha Level kwizigulana ezinesifo sentliziyo esinganyangekiyo. UZhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Ijenali yeTshayina yoNyango oluManyeneyo kunye neNtshona , I-US National Library of Medicine, kuJulayi 2010, www.ncbi.nlm.nih.gov/pubmed/20929124.
UZhang, Hong Wei, et al. I-Astragalus (iyeza leMveli laseTshayina) lokuNyanga iZifo zeZintso ezingapheliyo I-Cochrane Database yeeNkqubo eziPhononongo , I-US National Library of Medicine, i-22 Oct. 2014, www.ncbi.nlm.nih.gov/pubmed/25335553.
IYunivesithi ibonelela ngeendlela ezahlukeneyo zobungcali bobuchwephesha bokusebenza kunye nokudibanisa amayeza. Injongo yabo kukwazisa abantu abafuna ukwenza umahluko kwiinkalo zonyango ezisebenzayo ngolwazi abanokulunikezela.
VIDEO
by UGqr Alex Jimenez LweMpilo , impilo , IIrbs , isondlo , Ukuphila
Ngaba uziva:
Ukuvuvukala kumdibaniso kunye nomlomo? Amanqanaba eglucose akho akhuphuka kancinane? Ukuqunjelwa okungafunekiyo esiswini? Ukungalingani kweHormone? Ukutyeba kwakho?
Ukuba uhlangabezana naziphi na kwezi meko, ke kutheni ungazami ukongeza ezinye i-sage kwizitya zakho.
umba-
Kwihlabathi liphela kubugcisa beCoriyon kunye nehlabathi lezempilo, ukutya ngokwesiko kunye neendlela zokupheka ezinencasa zihlala zifuna iziqholo ezithile kunye namayeza anokongeza incasa yezitya umntu azityayo. Njengomzekelo, iitapile ezibhityileyo ngesinamon, kufana nokungcamla izulu. Naziphi na iimveliso zenyama okanye imifuno ziyachuma xa umntu ezohlwayela ezi mveliso ngamayeza amaninzi kunye neziqholo. I-herb salvia officinalis okanye i-sage igcwalisa umoya ngevumba layo kunye nokuphucula incasa yokutya okuninzi.
Njengawo nawuphi na amanye amayeza, i-sage yindlu enamandla emhlabeni wokutya okunesondlo. Izifundo zibonisa ukuba ingakanani inani leesaji ezinokuba nayo inani elincinci le micronutrients xa ilayita inkukhu kunye neentlobo ezahlukeneyo zeemveliso zenyama yezilwanyana. Yintoni emangazayo le herb kukuba ayisiyokwenza nje i-inkukhu yokunkcenkceshela umlomo, kodwa i-sage inokusetyenziswa njengeoyile efanelekileyo. Uphando lubonisa isoyile eyimfuneko yeoyile inokubonisa iziphumo ezichasayo nakweyiphi na intsholongwane eyingozi engena emzimbeni. Ikwanazo iipropathi ze-antioxidant ukukhusela umzimba kwi-lipid peroxidation.
Izibonelelo zeSage
Nazi Ezininzi iinzuzo ukuba i-sage inokubonelela umzimba kwaye inokukhusela iiseli zomzimba kwii-radicals zamahhala ezinokuthi zonakalisa umzimba kwaye ziphazamise kungekuphela nje ukhuselo lomzimba kodwa lunokuphuhlisa izifo ezingapheliyo. Ezinye zeepropathi eziluncedo ezinokubonelelwa yi-sage zezi:
Ukunyanga i-Alzheimer
I-Sage inokuba nefuthe elihle kwizakhono zokuqonda zomntu kwaye inokukhusela ubuchopho kukuphazamiseka kwemithambo-luvo, njengesifo i-Alzheimer's. Kuphando olutshanje , ibonakalise ukuba i-sage yi-arhente eyongezelelweyo yokwazisa ukwandisa ukusebenza kwengqondo. Ukusukela isheji isetyenziswe kunyango lwesintu ukunyanga uluhlu olubanzi lweengxaki kumgudu wokugaya ukutya kunye nokujikeleza komzimba. Inokonyusa ukusebenza kwengqondo kunye nengqondo ngokuphucula inkumbulo yomntu, ukukhawulezisa amandla abo okuqonda, kunye nokulibazisa naziphi na izifo ezinxulumene nobudala.
Iiglucose ezisezantsi kunye neCholesterol
I-Sage inokunceda ukunciphisa i-glucose yomzimba kunye namanqanaba e-cholesterol. Olunye uphando lubonakalisile indlela abathathi-nxaxheba abangama-40 abanesifo seswekile kunye ne-cholesterol ephezulu bathathe igqabi elinamagqabi angaphantsi kweenyanga ezintathu, kwaye iziphumo zimangalisa. Iziphumo zabonisa ukuba abathathi-nxaxheba babenomgangatho ophantsi weglucose kunye neqondo eliphantsi le cholesterol.
Olunye uphononongo olufunyenweyo ukuba abantu abanesifo seswekile se-2 basebenzisa i-sage ukunciphisa amanqanaba eswekile yegazi ukukhusela i-DKA (isifo seswekile ketoacidosis). Uphononongo lugqibe kwelokuba i-sage inokuba luncedo kuye nabani na onesifo seswekile ukunciphisa amanqanaba eglucose. Ngokusebenzisa i-sage ekutyeni komntu kuyamangalisa ngenxa yeepropathi ezibonelela kuye nabani na onokuba nenqanaba le-glucose ephezulu okanye iqondo eliphezulu le-cholesterol.
Iyanciphisa ukuvuvukala
Kukho ubungqina obungaphezulu bokuba isage inezinto ezithile ezinento yokwenza nokuchasana nokuvuvukala. Izifundo zibonisa loo sage inezibonelelo ezichasayo zokuchasana nokuvuvukala kwimizimba exhumeneyo yeentsini emlonyeni. Ipropathi yokuchasana nokuvuvukala kukaSage isetyenzisiwe eofisini yamazinyo kuba isetyenziswa njengesixhobo sokulwa umlomo ukubulala iintlungu ze-gingival fibroblasts.
Ukunciphisa iimpawu zokuyeka ukuya esikhathini
Xa umzimba ufumana ukwehla okungokwemvelo kwamahomoni, omabini amadoda kunye nabasetyhini banokuva ukuya esikhathini, kwaye oku kunokubangela uluhlu olubanzi lweempawu ezingathandekiyo nakubani na. Ukusuka kumalangatye ashushu, ukujuluka ngokugqithileyo, amanqanaba asezantsi e testosterone kunye ne-estrogen, ukutshintsha kwemozulu, nokuba nokuba nomsindo. Izifundo zibonise laa sage iqhelekileyo iye yasetyenziswa njengeyeza lemveli ukunciphisa iimpawu zokuya esikhathini ukuya emzimbeni. Nazi Izifundo ezininzi ziboniswa ukuba i-sage ineempawu ezifana ne-estrogen eziza kuvumela iikhompawundi ukuba zibophe kwi-neurological receptors kwingqondo ukuphucula imemori yokuqonda kunye nokusebenza komzimba.
isiphelo
Kukho izinto ezininzi ezisetyenziswayo ze-sage njengoko le herb iyindlu yombane xa kufikwa kwimveliso yemihla ngemihla. Isage inokude isetyenziselwe ukucoca ityhefu esemoyeni kunye neenkukhu ezinamaxesha kunye neentlobo ezahlukeneyo zenyama. Ngepropathi yayo yokuchasana nokuvuvukala, inokuthoba ukunganyangeki kwaye ithintele ekuguqukeni okungapheliyo emzimbeni. Ke ngoko ukongeza i-sage kwisitya akunakuphakamisa kuphela izitya ezifuna i-sage kwiindlela zokupheka kodwa kunokunika iipropati eziluncedo emzimbeni. Abanye iimveliso inokunceda ukuxhasa amajoni omzimba kwaye yenzelwe uzinzo olugqwesileyo, umsebenzi we-bioavailability, kunye nokugaya ukutya.
Ubungakanani bolwazi lwethu lukhawulelwe kwi-chiropractic, musculoskeletal, kunye nemicimbi yezempilo yovalo okanye amanqaku amayeza asebenzayo, izihloko kunye neengxoxo. Sisebenzisa iiprothokholi zempilo ezisebenzayo ukunyanga ukwenzakala okanye ukuphazamiseka kwenkqubo yemusculoskeletal. Iofisi yethu yenze umzamo oqinisekileyo wokubonelela ngezikhokelo ezixhasayo kwaye ichonge isifundo sophononongo esifanelekileyo okanye izifundo ezixhasa izithuba zethu. Sikwenza iikopi zezifundo zophando ezixhasayo ziya kufumaneka ebhodini okanye kuluntu xa luceliwe. Ukuqhubeka nokuxoxa ngomxholo ongentla, nceda ukhululeke ukubuza uGqirha Alex Jimenez okanye unxibelelane nathi apha 915-850-0900 .
Iingxelo:
Bozin, Biljana, et al. �IiPropati zeAntimicrobial kunye ne-Antioxidant yeRosemary kunye neSage (Rosmarinus Officinalis L. kunye neSalvia Officinalis L., Lamiaceae) i-Oli eziBalulekileyo.� Umbhalo wezoLimo lwezoLimo noLimo , I-US National Library of Medicine, i-19 Septemba. 2007, www.ncbi.nlm.nih.gov/pubmed/17708648.
Fawzi, Muntaha, et al. �Impembelelo yeSage echasene nokudumba (Salvia officinalis) iCwangcisa i-ABSTRACT kwiMpilo yoMlomo.� Ijenali yamazinyo e-Iraqi , Ngo-2017, iraqidentaljournal.com/index.php/idj/article/view/111/69.
Kargozar, Rahele, et al. �Uphononongo lwamaYeza asebenzayo eHerbal ekulawuleni iimpawu zokuya exesheni.� Ugqirha we-Elektroniki , Ugqirha we-Elektroniki, nge-25 Novemba.I-2017, www.ncbi.nlm.nih.gov/pubmed/29403626.
Lopresti, Adrian L. �Salvia (Sage): Uphononongo lweZiphumo ezinokuthi zibeKho zokuPhumelela kwengqondo kunye noKhuseleko.� Iziyobisi kwiR & D , Ukupapashwa kwe-Springer International, ngoMatshi 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5318325/.
Rahte, Sinikka, et al. �ISalvia Officinalis yeeFlushi ezishushu: ejolise ekuMiseni inkqubo yoMsebenzi kunye neMigaqo eSebenzayo.� Planta Medica , I-US National Library of Medicine, ngo-Juni 2013, www.ncbi.nlm.nih.gov/pubmed/23670626.
Iqela, DFH. �I-Sage yiyo yonke ingqumbo (okanye ubuncinane imele ibenjalo!).� Uyilo lwezeMpilo I-23 ngoDisemba ngo-2019, ibhlog.designsforhealth.com/node/727.
Ware, uMegan. �Sage: IiNzuzo zeMpilo, iiNyaniso, kunye noPhando.� News Today , I-MediLexicon International, i-10 Jan. 2018, www.medicalnewstoday.com/articles/266480.php.
Intsebenzo yanamhlanje kunye nokuSebenza kakuhle- Esse How Videri
VIDEO
Ngokwazisa umntu malunga neDyunivesithi yeSizwe yezeNzululwazi yezeMpilo ibonelela ngolwazi kwizizukulwana ezizayo ezifuna ukwenza umohluko emhlabeni. IYunivesithi ibonelela ngeendlela ezahlukeneyo zobungcali bobuchwephesha bokusebenza kunye nokudibanisa amayeza.
by UGqr Alex Jimenez LweMpilo , impilo , IIrbs , isondlo , Ukuphila
Ngaba uziva:
Ukuqunjelwa okungafunekiyo esiswini? Ukungalingani kweHormone? Uxinzelelo ngamanye amaxesha? Ukudumba emathunjini? Ukutyeba kwakho?
Ukuba ufumana nayiphi na yezi meko, kutheni ungazami ezi zityalo zebhotani kwisitya sakho sokutya.
Ixesha leeholide lizisa uvuyo kubantu abanezithethe zeeholide kunye nokutya okukhethekileyo, okuqhelekileyo, iziselo, imifuno yonyaka, neziqholo etafileni. Amaxesha onyaka abandayo kulapho wonke umntu wase-US ezonwabisa ngeesuphu ezityebileyo, iimveliso zeziqholo zamathanga, imifuno yeengcambu, kunye nentsalela ye-turkey. Izinto ezininzi zemenyu yeeholide ziza kubandakanya imifuno emnandi kunye ne-savory kunye neziqholo kwizitya zabo zokutya. Into abantu abangayiqondiyo kukuba nangona ezi zityalo kunye neziqholo ziphucula incasa yokutya, zikwabonelela ngentaphane yeenzuzo zempilo kumzimba. Ngoko ukusebenzisa ezi zityalo neziqholo ekhitshini kunokunceda ekwandiseni amathuba omntu okufumana iimpawu zawo eziluncedo, kungoko “okukhona kusiba mnandi.”
Ukutyhubela iinkulungwane, izityalo zonyango ziye zasetyenziswa ngokwesiko ziinkcubeko ezahlukeneyo. Ezinye zezityalo ezinamandla kakhulu zendalo zisetyenziselwa izitya zokupheka, ngelixa zibonelela ngeempawu ezincedo kumzimba womntu; zi rosemary, sage, kunye clove.
IRosemary
Ekubeni isetyenziswa ngokuqhelekileyo njenge-condiment kunye ne-preservative yokutya, i-rosemary sisityalo somthonyama kummandla weMeditera. Uphengululo wenza uphando lwezilwanyana kwi-vivo kunye ne-in vitro ebonisa ukuba i-rosemary ibonise iziphumo eziluncedo ezifanayo kuwo nawaphi na amayeza eentlobo ezahlukeneyo zokuphazamiseka komzimba. Ezinye zeengxaki ze-physiological ziquka:
Lead hepato-nephrotoxicity istres Ukuxhalabisa Ubunzima bomzimba kunye ne-dyslipidemia Ubuhlungu Cerebral ischemia
Olunye uphononongo yayijonge ukuba irosemary ineempawu ze-antimicrobial kunye ne-antioxidant kwaye ubuninzi bayo kwi-isoprenoid quinones. Uphononongo luchaze ukuba i-rosemary inokuthi �isebenze njengee-terminators ze-chain for radicals zamahhala kunye ne-chelators ye-ROS (iintlobo ze-oksijini ezisebenzayo.) "Iipropati ze-antioxidative kwi-rosemary zinobuninzi be-phenolic diterpenes; njenge-carnosic acid kunye ne-carnosol, ezinoxanduva malunga ne-90% yale mifuno. Ekubeni inqanda i-lipid peroxidation, i-scavenge radicals, kwaye inceda ukunciphisa i-cytochrome c ngokuvula iindlela zokubonisa ezixhomekeke kwi-redox emzimbeni.
Nge-carnosic acid, ibonakaliswe ukubonelela ngezenzo eziphezulu ze-antimicrobial kwezinye izinto ezibalulekileyo ezifumaneka kwi-rosemary. Ngapha koko, kukho izifundo ezibonisiweyo ukuba irosemary inamandla okulwa ne-antibacterial ngokuchasene neebhaktheriya ezixhathisayo emzimbeni.
umba-
ISage yenye imifuno eyinzalelwane yeMeditera nakuMbindi Mpuma kwaye isetyenziswe kumayeza esintu ukunyanga izifo ezahlukeneyo emzimbeni. Nantsi lapho uphando lwangoku ecebise ukuba i-sage inokuba noluhlu olubanzi lweepropathi eziluncedo kumzimba ngenxa yobukho be-carnosic acid kunye ne-carnosol kule mifuno. Olunye uphando ibonise ukuba i-sage iqulethe imixholo ephezulu ye-glycosidic flavones enika amandla okuthintela umsebenzi ngokuchasene nomsebenzi we-xanthine oxidase emzimbeni. Ezinye zeempawu eziluncedo ziquka:
Ulwaphulo-mthetho I-Antinociceptive Intsholongwane I-Hypoglycemic I-Antioxidative
Kukho uphando olongezelelweyo olubonisa ukuba i-sage ineepropathi ezinamandla zokuphucula ingqondo kunye ne-neuroprotective. Izifundo zibonisa ukuba izigulane ezine-Alzheimer's disease zithatha i-4-month supplementation ye-sage, kwaye iziphumo ziyamangalisa. Izigulana ze-Alzheimer ziye zafumana ukuphucuka okubalulekileyo ekusebenzeni kwazo kwengqondo kunye nokuphucula imo. Kwesinye isifundo, isicatshulwa se-sage sinokunceda ukunciphisa ubunzima beenkqubo zomzimba nezengqondo ezifunyenwe kwi-premenstrual syndrome emzimbeni.. Inqaku lakutshanje liye labonisa amagqabi e-sage asandul' ukuvunwa anokuba yimodyuli enamandla yeendlela ze-neuroreceptor ezibandakanya abathuthi be-serotonin abanokuthi bancede ukuqhelanisa i-thermoregulation kunye nokuphazamiseka kwengqondo kwabasetyhini abakwi-menopausal.
Okumangalisayo kukuba, zombini irosemary kunye ne-sage zibonakalisiwe kwaye zibonisiwe ukuba zinokunceda ukuphucula iindlela ze-gabaergic kwingqondo kwaye zinokunceda ukunciphisa imisebenzi ye-neuronal ehambelana nokuphazamiseka kwexhala. Izifundo zibonisa ukuba i-rosemary kunye ne-sage extracts zinendima ye-hepatoprotective kunye ne-antioxidative enokunyusa i-catalase kunye namanqanaba e-glutathione kunye nokunciphisa i-lipid peroxidation emzimbeni.
Iingubo
I-clove buds yafunyanwa ekuqaleni kwimpuma ye-Indonesia, kwaye idlala indima njengoko imifuno ine-antimicrobial enamandla kunye ne-antioxidative botanical. Uphando lubonisa ukuba ioyile ye-clove inefuthe le-bactericidal ngokuchasene neentlobo ze-pathogenic ezinokwenzakalisa umzimba. Ekuqaleni kwalo nyaka, isifundo sophando yafumanisa ukuba i-clove yeoli ye-clove inokunyusa umsebenzi wokuchasana nokuvuvukala ngokunciphisa umsebenzi we-myeloperoxidase kwi-neutrophils yabantu kakhulu. Le mifuno inokunceda ukunciphisa i-ROS kunye neentlobo ezahlukeneyo zabalamli abavuthayo abanokukhuthaza umonakalo omkhulu kumzimba kwindawo yokuvuvukala.
isiphelo
Ngoko ngeeholide, ukongeza ezi zityalo ezintathu ezinamandla kwisidlo esilandelayo seeholide azikho nje ukunceda ukunyusa i-flavour yezitya, kodwa ziluncedo kumzimba. Ekubeni banikezela ngeempawu ezichasayo kumzimba ngokunciphisa iimpendulo ezivuthayo. Ke kumaxesha onyaka abandayo, yongeza i-dash eyongezelelweyo yemifuno kwiresiphi yesitya iya kwenza ukuba imini yakhe yonwabe. Abanye iimveliso zikhethekileyo ekubaleni iziphumo ze-metabolic zoxinzelelo lwexeshana kwaye zinokuxhasa umzimba.
Ubungakanani bolwazi lwethu lukhawulelwe kwi-chiropractic, musculoskeletal, kunye nemicimbi yezempilo yovalo okanye amanqaku amayeza asebenzayo, izihloko kunye neengxoxo. Sisebenzisa iiprothokholi zempilo ezisebenzayo ukunyanga ukwenzakala okanye ukuphazamiseka kwenkqubo yemusculoskeletal. Iofisi yethu yenze umzamo oqinisekileyo wokubonelela ngezikhokelo ezixhasayo kwaye ichonge isifundo sophononongo esifanelekileyo okanye izifundo ezixhasa izithuba zethu. Sikwenza iikopi zezifundo zophando ezixhasayo ziya kufumaneka ebhodini okanye kuluntu xa luceliwe. Ukuqhubeka nokuxoxa ngomxholo ongentla, nceda ukhululeke ukubuza uGqirha Alex Jimenez okanye unxibelelane nathi apha 915-850-0900 .
Iingxelo:
Chniguir, Amina, et al. �I-Syzygium Aromaticum i-Aqueous Extract inqanda i-Neutrophils yoMntu i-Myeloperoxidase kwaye ikhusela iimpuku kwi-LPS-Induced Lung Inflammation.� Biyeza , Taylor & Francis, Dec. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6366422/#!po=2.63158.
Choukairi, Zineb, et al. �Impembelelo yeSalvia Officinalis L. kunye noRosmarinus Officinalis L. Amagqabi aKhethiweyo kwiNgxaki kunye noMsebenzi weNeural.� Ulwazi lwebhayoloji , i-Biomedical Informatics, nge-15 kaMatshi 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6637401/.
de Oliveira, Jonatas Rafael, et al. �Rosmarinus Officinalis L. (Rosemary) njenge-Arhente yoNyango kunye neProphylactic.� Ijenali yeSayensi yeBiomedical , BioMed Central, 9 Jan. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6325740/.
Lopresti, Adrian L. �Salvia (Sage): Uphononongo lweZiphumo ezinokuthi zibeKho zokuPhumelela kwengqondo kunye noKhuseleko.� Iziyobisi kwiR & D , Ukupapashwa kwe-Springer International, ngoMatshi 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5318325/.
UNieto, uGema, et al. �IiPropathi zeAntioxidant kunye neAntimicrobial yeRosemary (Rosmarinus Officinalis, L.): Uphononongo.� Amayeza (Basel, Switzerland) , MDPI, 4 Septhemba. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6165352/.
Pavi?, Valentina, et al. �Ukutsalwa kweCarnosic Acid kunye neCarnosol kwiSage (Salvia Officinalis L.) Amagqabi ngeSupercritical Fluid Extraction kunye nomsebenzi wabo weAntioxidant kunye neAntibacterial.� Izityalo (eBasel, eSwitzerland) , MDPI, 9 kaJanuwari ka-2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6359053/.
Pereira, Ol�via R, et al. �USalvia Elegans , USalvia Greggii kwaye ISalvia Officinalis I-Decoctions: Imisebenzi ye-Antioxidant kunye nokuThintelwa kweCarbohydrate kunye ne-Lipid Metabolic Enzymes. IMolekyuli (iBasel, eSwitzerland) , MDPI, 1 Dec. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6321363/.
Iqela, DFH. �Sinonge iiHolide ngeZityalo zaMayeza.� Uyilo lwezeMpilo I-25 Nov. 2019, blog.designsforhealth.com/node/1156.
UTober, uCarsten, kunye noRoland Schoop. �Ukumodareyithwa kweNdlela zeNeurological nguSalvia Officinalis kunye nokuxhomekeka kwayo kwiNkqubo yokuVelisa kunye neZityalo ezisetyenzisiweyo.� IBMC yokuGqibezela kunye neNyango elingelinye , I-BioMed Central, nge-13 kaJuni ngo-2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6567565/.
by UGqr Alex Jimenez LweMpilo , impilo , IIrbs , isondlo , Ukuphila
Ngaba uziva:
Unexhala okanye awukwazi ukugxila kwimisebenzi? Ngaba iingxaki zokwetyisa ziyehla xa uphumla okanye uphumle? Ubuhlungu besisu, ukutsha, okanye ukuqaqanjelwa kwe1-4 iiyure emva kokutya? Ulusu olubomvu? Isicaphucaphu okanye ukugabha?
Ukuba ujongene nazo naziphi na kwezi meko, ngoko usenokuba noxinzelelo lokwetyisa. Zama i-chamomile ukunciphisa ukuba uxinzelelo kunye nengqondo exhalabileyo.
I-Chamomile kunye neemveliso zayo ziyaziwa ngokukhuthaza isimo sengqondo esiphilileyo kunye nokuphucula umgangatho wokulala omangalisayo kuye nabani na othatha eli sityalo. Le ntyatyambo imhlophe kunye netyheli, nangona kunjalo, ineenzuzo ezininzi zempilo ezithandekayo eziluncedo kuye nabani na oziva exhalabile kubomi bakhe bemihla ngemihla, obuxakekileyo kwaye inokubonelela ngolunye uncedo kumzimba onezigulo ezithile.
Yintoni iChamomile?
IChamomile sisityalo sakudala samayeza sosapho lwe Asteraceae kwaye isoloko isaziwa njenge "apile lomhlaba phantsi" ngenxa yevumba elimnandi elifana ne-apile eliyivelisayo. Iintyatyambo zineempawu ezikhethekileyo ezinokomeleza impilo-ntle yomntu kunye nokubonelela ngezondlo eziluncedo eziphawuleka ukuba umzimba uphumle kwaye uzive uzolile. Esi sityalo sele sikhona kangangeenkulungwane kwaye sivela empuma nakumazantsi eYurophu. Iitoni zophando zibonisile ukuba i-chamomile isetyenziswe kumayeza emifuno kumaxesha amandulo ngexesha lamaRoma, ixesha lamaGrike kunye neYiputa. Esi sityalo sinesiqu esicekethekileyo esimile okwe-spindle esivelisa iintyatyambo ezincinci ezifana nedaisy.
Iinzuzo zeChamomile
Imichiza ye-chamomile inokusebenza njenge-antioxidants emzimbeni womntu kwaye inokuthintela ukuvutha ukuba kwenzeke. Ngenxa yoku, xa umntu esitya iimpahla ze-chamomile; Iipropathi zempilo zinokunceda ukuthintela ukubanda okuqhelekileyo, ukuphazamiseka kwamathumbu emathunjini, ukudumba kunye nezigulo ezininzi zomzimba ezinokuchaphazela umzimba womntu ukuba usebenze ngokufanelekileyo. Kukho iintlobo ezimbini ze-chamomile ezineempawu ezimangalisayo eziye zasetyenziselwa amayeza endalo yi-chamomile yaseJamani kunye ne-chamomile yaseRoma.
Chamomile yaseJamani : Olu hlobo lwe-chamomile luthandwa kwihlabathi jikelele kwaye luzalelwa kumazantsi nasempuma yeYurophu. Izifundo zibonise ukuba abantu baya kuthatha i-chamomile ngomlomo ukukhulula izigulo ezibangelwa yimiba yokusingqongileyo. Kukho abanye abantu abaya kuthi basebenzise i-chamomile eluswini lwabo njenge-ointment. Kukho ubungqina besayensi bokuba ukusebenzisa i-chamomile yaseJamani njengerinse yomlomo kunokuba luncedo kwizigulana ezinomhlaza ezine-mucositis, ekukudumba kunye nokudumba kwenwebu ye-mucosal ekwindlela yokwetyisa okubangelwa yichemotherapy kunye neradiotherapy.I-Chamomile yaseRoma : Olu hlobo lwe-chamomile lubonelela ngeenzuzo ezifanayo njenge-German Chamomile njengoko ikhulula izifo ezifanayo ezibangelwa yimeko yendalo kodwa inika uncedo olungakumbi kumzimba. I-chamomile yamaRoma ineempawu ze-hypnotic ezinceda umntu ukuba aphumle kwaye alale ngokukhawuleza. Zikhona ibe zizifundo ukuba le mifuno inika iziphumo ze-hypnotic kwizilwanyana kwaye xa idliwe, yanciphisa ixesha lokuba balale.
Izibonelelo ezibonelelwa ngesityalo se-chamomile kukuba ikhuthaza umzimba ukuba uphumle kunye nezinye izibonelelo eziyimfuneko kumzimba. Xa isetyenziswa njengeoyile ebalulekileyo yearomatherapy, isigulana sinokuziva sixhalabile kancinci xa siphefumla umphunga kwaye ekugqibeleni sivumele ingqondo yabo exhalabileyo iphumle.
Ukunciphisa Iintlungu
Impembelelo echasayo yokuba zombini ioli efunekayo kunye nentyatyambo ye-chamomile ngokwayo inokunceda umzimba ngokunciphisa intlungu edibene nayo. Ukusukela ukuba isityalo se-chamomile sisetyenziselwe amakhulu, abantu bebesebenzisa esi sityalo ukunceda ukunciphisa iintlungu ezivela kwiimpawu ezinxulumene nokudumba emzimbeni abanokuba nazo.
Izifundo zibonise ukuba abantu abasebenzisa iti ye-herbal ngenxa yokudumba kwabo ngokudibeneyo baye babonisa ukuphucuka ngokukodwa emadolweni kunye nomqolo ophantsi. I-antioxidant kunye ne-anti-inflammatory properties le tea ye-herbal ivelisa i-polyphenols echaphazela ukuvuvukala kwenkqubo kunye nomsebenzi odibeneyo emzimbeni. Olunye uphando lubonisa ukuba abaguli abane-knee osteoarthritis basebenzisa ioli ye-chamomile ukunciphisa ukuqina kwamalungu abo kwaye banike iziphumo eziluncedo kumsebenzi wabo womzimba.
Uphilisa kwaye Ukhuthaza iMpilo yolusu
Nabani na onesifo se-eczema kwaye asebenzise iikhrimu ze-topical ukunciphisa ububomvu, banokufuna ukuzama ukusebenzisa i-chamomile ioli ebalulekileyo. Iinzuzo zokusebenzisa i-chamomile ioli efunekayo kukuba inokunceda ukunciphisa ulusu olunomsindo. Umntu unokuxuba i-chamomile ioli efunekayo kunye neoli ye-carrier okanye i-lotion kwaye uyifake esikhumbeni sabo njengoko i-anti-inflammatory kunye ne-antibacterial properties ingathomalalisa isikhumba esibomvu, esomileyo, esicaphukileyo ngelixa inciphisa ukuqhambuka ukuba kwenzeke.
Kwezinye iimeko, kuye kwakho iingxelo zokuba i-chamomile isebenze ngakumbi kune-hydrocortisone lotion yezilonda zesikhumba. Abaphandi bafunyenwe kwi uphando lwe-2010 , ukuba ioli yaseJamani i-chamomile isetyenziselwe ukudambisa i-atopic dermatitis, eyona ngxaki yesikhumba engapheliyo, ngokuqulatha izinto ezintathu eziphambili ze-sesquiterpene (i-azulene, i-bisabolol, kunye ne-farnesene) ngokuphilisa ulusu ngokuthe ngcembe.
Ukuphucula Ukwetyisa
Olunye usetyenziso oluxhaphakileyo lwe-chamomile, ngakumbi xa luxutywa kwiti, lunciphisa iimpawu ezingafunekiyo ezihambelana nokungacoci kakuhle kwindlela yokugaya. Ngeti ye-chamomile, inokuthomalalisa isisu esibuhlungu, ukukrala, ukuqunjelwa, kunye norhudo. Iikhompawundi zonyango ezifumaneka kwi-chamomile zinokusebenza njenge-digestive relaxant.
Ukuphucula ukulala kunye nokuPhumla
Xa igalelwe iti, i-chamomile inokukhuthaza isakhelo somntu engqondweni kwaye inokuphucula umgangatho wabo wokulala ukuze ibanike iiyure ezi-8 eziyimfuneko zokulala. Uphando lubonisa ukuba abantu abasela iti ye-chamomile ngaphambi kokuba balale, balale ngcono ebusuku kwaye baphumle kancinci. I-Apigenin ibonelela ngesiphumo esivuselelayo esivela kwiti ye-chamomile kwaye ibopheleleka kunye ne-benzodiazepine receptors kwingqondo, ibonelela ngeenzuzo ezinokunceda ukunciphisa uxinzelelo oluvela emzimbeni ngelixa ikwakhuthaza ukulala kamnandi ebusuku.
In uphando lwe-2017 , Uphando lubonisa ukuba abantu abadala abangaphezu kweminyaka engama-60 badla iti ye-chamomile ngaphambi kokuba balale. Iziphumo zibonise ukuba umgangatho wabo wokulala uphuculwe ngokunciphisa iingxaki zokulala ezifana ne-apnea yokulala kunye nokusetyenziswa kweyeza lokulala ngelixa bephucula iimvakalelo zabo kakhulu ngokuhamba kwexesha.
Ukuphucula impilo yengqondo
Ukusebenzisa iimveliso ze-chamomile kunokunceda umntu ukuba aphile. Ekubeni i-chamomile ineepropathi ezinenzuzo yokwenza umzimba ukhululeke, inokunceda ukunciphisa ukuvakalelwa kokudakumba kunye nokuxhalaba kumntu xa idliwe. Izifundo zithe ukuba ukuthatha ixesha elide kwe-chamomile kukhuselekile kwaye kunokunciphisa kakhulu imiphumo ye-GAD ephakathi ukuya kwiimpawu ezinzima emzimbeni. Kwanokusebenzisa ioyile yearomatherapy kunokuthathwa njengenye indlela yonyango kwizigulana.
isiphelo
Ngaloo ndlela i-chamomile sisityalo esisebenzayo nesikhuselekileyo esiye sasetyenziswa ngabantu abaye bafumana inani leempawu. Ekubeni i-chamomile igqwesileyo ekunciphiseni intlungu, ibe nolusu olungcono, ukuphucula impilo yengqondo kunye nokubonelela ngezinto ezininzi ezincedo. Xa isetyenziswa kwi-aromatherapy okanye idliwe emzimbeni, i-chamomile lunyango lwendalo lwengqondo yovalo. Ezinye iimveliso idityaniswe ne-chamomile zenzelwe ukunika inkxaso kwindlela yesisu kunye nokuqinisekisa ukuba i-metabolism yeswekile isebenza ngokufanelekileyo.
Ubungakanani bolwazi lwethu lukhawulelwe kwi-chiropractic, musculoskeletal, kunye nemicimbi yezempilo yovalo okanye amanqaku amayeza asebenzayo, izihloko kunye neengxoxo. Sisebenzisa iiprothokholi zempilo ezisebenzayo ukunyanga ukwenzakala okanye ukuphazamiseka kwenkqubo yemusculoskeletal. Iofisi yethu yenze umzamo oqinisekileyo wokubonelela ngezikhokelo ezixhasayo kwaye ichonge isifundo sophononongo esifanelekileyo okanye izifundo ezixhasa izithuba zethu. Sikwenza iikopi zezifundo zophando ezixhasayo ziya kufumaneka ebhodini okanye kuluntu xa luceliwe. Ukuqhubeka nokuxoxa ngomxholo ongentla, nceda ukhululeke ukubuza uGqirha Alex Jimenez okanye unxibelelane nathi apha 915-850-0900 .
Iingxelo:
Abdullahzadeh, Mehrdad, et al. �UPhando lweMpembelelo yeChamomilla yoMlomo kuMgangatho wokuLala kubantu abaDala e-Isfahan: Uvavanyo olungenamkhethe lolawulo.� Ijenali yeMfundo kunye nokuKhuthazwa kwezeMpilo , Medknow Publications & Media Pvt Ltd, 5 June 2017, www.ncbi.nlm.nih.gov/pubmed/28616420.
Charosaei, Firuzeh, et al. � Ukusebenzisa i-Chamomile Solution okanye i-1% ye-Topical Hydrocortisone Ointment kuLawulo lwe-Peristomal Skin Lesions kwi-Colostomy Patients: Iziphumo zoPhononongo lweKlinikhi oluLawulwayo.� Ulawulo lwe-Ostomy / Inxeba , I-US National Library of Medicine, ngoMeyi 2011, www.ncbi.nlm.nih.gov/pubmed/21617262.
UChristiansen, uSherry. �IiNzuzo zeMpilo zeRoman Chamomile.� Impilo entle kakhulu , Verywell Health, 14 Jan. 2019, www.verywellhealth.com/roman-chamomile-4571307.
Drummond, Elaine M, et al. �Uphononongo lweVivo oluvavanya iZiphumo ezichasene nokudumba kweChamomile, iMeadowsweet, kunye ne-Willow Bark kwiNoveli yesiSiselo esiSebenzayo.� Ijenali yezongezo zokutya , I-US National Library of Medicine, ngoDisemba 2013, www.ncbi.nlm.nih.gov/pubmed/24237191.
Iqela lezeMpilo, i-eMedicine. �IChamomile yaseJamani:Ukusetyenziswa, iZiphumo ezisecaleni, uThamo, ukuSebenzisana kunye neeNzuzo zeMpilo.� EMedicineHealth , EMedicineHealth, 17 Septemba 2019, www.emedicinehealth.com/german_chamomile/vitamins-supplements.htm.
UMao, uJun J, kunye nabanye. �Unyango lweChamomile lweXesha elide (i-Matricaria Chamomilla L.) Unyango lweSifo sokuxhalaba ngokuBanzi: uLwango loNyango lwezonyango.� I-Phytomedicine : Ijenali yeHlabathi yePhytotherapy kunye nePhytopharmacology , ILayibrari yeSizwe yezoNyango yase-US, i-15 Dec. 2016, www.ncbi.nlm.nih.gov/pubmed/27912875.
Shoara, Ruhollah, et al. �Ukusebenza kunye noKhuseleko lwe-Topical Matricaria Chamomilla L. (Chamomile) I-Oli ye-Knee Osteoarthritis: Ulingo lweKlinikhi oluLawulwayo ngokungenamkhethe.� Unyango olugqibeleleyo kwiKliniki yokuziQhelanisa , I-US National Library of Medical, Aug. 2015, www.ncbi.nlm.nih.gov/pubmed/26256137.
Singh, Ompal, et al. �Chamomile (Matricaria Chamomilla L.): Isishwankathelo.� UPhononongo loPhando , I-Mednow Publisher Pvt Ltd, Jan. 2011, www.ncbi.nlm.nih.gov/pmc/articles/PMC3210003/.
Srivastava, Janmejai K, et al. �IChamomile: Iyeza Lezityalo Lakudala Elinekamva Eliqaqambileyo.� Iingxelo zeMolekyuli yamayeza , ILayibrari yeSizwe yeSizwe yezoNyango yase-US, i-1 Nov. 2010, www.ncbi.nlm.nih.gov/pmc/articles/PMC2995283/.
by UGqr Alex Jimenez Ubuhlungu obungapheliyo , IIrbs , nethamarikhi
Intlungu engapheliyo yenye yezona meko zixhaphakileyo eMelika, ichaphazela uqikelelo 100 izigidi zaseMerika ngonyaka nganye. Ukubeka loo nto ngokwembono, lingaphezulu kwenani labantu abanomhlaza, isifo sentliziyo kunye nesifo seswekile, zidibene .
Uninzi lwaba bantu baneentlungu ezinganyangekiyo bajonge uncedo ngaphandle kwamayeza anokuba nemiphumo emibi engalunganga. Oku kubazisile kwiindlela zokulawulwa kweentlungu zendalo njengokukhathalela i-chiropractic kunye nezinto zendalo ezinje nge-curcumin. Kubantu abaninzi, ezi ndlela zonyango zibazisele isiqabu kwintlungu kwaye zabanceda babuyela kwindlela eqhelekileyo.
Isebenza njani kodwa? Kwaye, okubaluleke ngakumbi, ngaba inokusebenza kuwe?
Yintoni i-Curcumin?
I-herbal yemvelo Iicotmeric zeetapile ezinamagqabi amatsha e-herb kunye ne-curcumin eyomileyo ephepheni
I-Curcumin sisinongo esisihlobo se-ginger kwaye siyinxalenye ye-turmeric. Rhoqo e-US, amagama athi i-curcumin kunye ne turmeric asetyenziswa ngokuchaseneyo. Nangona kunjalo, i-curcumin yinto enika i-turmeric umbala wayo ophuzi ophuzi.
Ngelixa ihlala ifumaneka kwii-curries kunye nokunye ukutya kwendabuko kwaseIndiya, kudala isetyenziselwa ukunyanga imiba eyahlukeneyo yezempilo kubandakanya ukuvuvukala okubangela intlungu emzimbeni. La mabango axhaswe zizifundo ezininzi ezibonisa ukuba izinongo zakhe zinambitheka kakhulu.
Olu phononongo lubonise ukuba i-curcumin inayo iipropathi ezichasene nokuvuvukala nangona kutheni isebenza ingekaqondwa ngokupheleleyo. Olu lwazi luvuselele izifundo ezizezinye ukufumanisa ukusebenza kwe-curcumin kunyango lweemeko ezahlukeneyo kubandakanya neentlungu ezinganyangekiyo.
Olunye uphononongo luphonononge iziphumo zeziqholo kubantu abanesifo samathambo okanye iintlungu zamalungu. Iziphumo zafumanisa ukuba i-turmeric extract (curcumin) izongezelelo zilungile Isebenza njenge ibuprofen ekunciphiseni iintlungu kwizigulana ezinamalungu edolo. Incede ekunciphiseni ukuvuvukala okwakubangela intlungu, kusizisela abaguli uncedo oluyidingayo.
Ukuthatha i-Curcumin yeMpilo eNgcono
Unokufumana i-curcumin okanye i-turmeric supplements, kodwa akukho lwazi lomgangatho olukhoyo. I-chiropractor yakho inokucebisa malunga nokuthatha kwaye yeyiphi i-brand eyongezelelweyo ehamba phambili.
Unokusebenzisa nesiqholo kukutya okutyayo kwaye ufumane ubuncinci bepropathi yempilo ngaloo ndlela. Nangona kunjalo, kunokuba yinto efanelekileyo kwaye ikhululekile ngakumbi ukuthatha i-curcumin okanye i-turmeric supplements, ngakumbi xa unyanga ukuvuvukala kunye nentlungu.
I-Curcumin ikhuselekile ngokubanzi ineziphumo ezimbalwa ebezingalindelekanga. Njengalo naluphi na amayeza okanye izongezo, abanye abantu banolwazelelelo ngesinongo kwaye banokufumana urhudo kunye nesipaphu.
Nangona kunjalo, oko kudla ngokwenzeka kwiidosi eziphezulu okanye emva kokuba isiguli sizisebenzise ixesha elide. Amayeza aphezulu anokubeka emngciphekweni ukuba umntu unezilonda. Inokukwacaphukisa ulusu isetyenziswe ngokuphezulu.
Ukuba ucinga ukufaka i-curcumin kwisidlo sakho semihla ngemihla njengesongezelelo sezempilo, kufuneka uqale uthethe nogqirha wakho okanye i-chiropractor ukuze uqiniseke ukuba ikhuselekile. Abasetyhini abakhulelweyo okanye abancancisayo akufuneki bathathe izongezo.
Abantu abaneemeko ezinje ngesifo seswekile, imbandezelo ye-gallbladder, ukuphazamiseka kwegazi, isifo sezintso, okanye iingxaki zokungakhuseki kufuneka bathabathe ukhathalelo olukhethekileyo xa besebenzisa izongezelelo. Kananjalo iyakwazi ukusebenzisana namayeza afana ne-NSAIDs, i-aspirin, iziyobisi zesifo seswekile, ii-statins, igazi elincinci, kunye neyeza zoxinzelelo lwegazi ngoko ke thetha nengcali yakho yezempilo, enje nge-chiropractor yakho, ngaphambi kokuba uthathe. Banokuyihlengahlengisa i-dosage yakho okanye bacebise unyango oluthile lwesondlo ukuxhasa ngcono isongezelelo.
akho chiropractor inokukunceda uphile ubomi bendalo obungaphaya kobuhlungu, ngaphandle kwentlungu kwaye izongezo ezinje nge-curcumin zinokuba yinxalenye yesicwangciso. Banokukunceda ukuba usendleleni eya kubomi obuphilwa kakuhle.
Ukwelashwa Kwangaphantsi kwemivuzo
VIDEO
by UGqr Alex Jimenez Ukuguga , Ukuxutyushwa , Ukutya , LweMpilo , impilo , IIrbs , Medicine Holistic , WeMpilo yeNdalo , isondlo , Uxinzelelo oluxhasayo , ulungiso , nezongezo , Unyango , Ukuphila
The i-nyukliya erythroid I-2 enxulumene ne-2 yokubonisa indlela , eyaziwa ngokuba ngu-Nrf2, yindlela yokukhusela esebenza "njengomlawuli oyintloko" wempendulo yomzimba womntu olwa ne-antioxidant response. I-Nrf2 ivala amanqanaba okuxinwa kwe-oxidative ngaphakathi kweeseli kwaye ibangela iindlela ezikhuselayo zokukhusela i-antioxidant. Nangona i-Nrf2 isebenze inokufumana inzuzo eninzi, i-Nrf2 "ukugqithiseleka" inokuba nemingcipheko emininzi.
Kubonakala ukuba i-NRF2 ibaluleke kakhulu ekuthintela ukuphuhliswa jikelele kwezifo ezahlukeneyo ngaphezu kokuphucula ngokubanzi le micimbi yezempilo. Nangona kunjalo, i-NRF2 inokubangela iingxaki. Isizathu esibangeleyo emva kwe-NRF2 "ukugqithisa kakhulu" ngenxa yokuguquka komzimba okanye ukuqhubela phambili okungapheliyo kwimizi yeciksi okanye ukuxinzezeleka kwengcinezelo, phakathi kwabanye. Ngezantsi, siza kuxubusha ukuhlaselwa kwe-Nrf2 ngokugqithiseleyo nokubonisa iindlela zayo zokusebenza ngaphakathi komzimba womntu.
Cancer
Izifundo zophando zifumanise ukuba iimpuku ezingachazi i-NRF2 zithambekele ngakumbi ekuphuhliseni umhlaza ekuphenduleni ukuvuselela komzimba kunye neekhemikhali. Izifundo ezifanayo zophando, nangona kunjalo, zibonise ukuba ukusebenza kwe-NRF2 ngaphezulu, okanye ukungasebenzi kwe-KEAP1, kunokubangela ukonyuka komhlaza othile, ngakumbi ukuba ezo ndlela ziphazamisekile. I-NRF2 egqithisileyo inokubakho ngokutshaya, apho ukusebenza okuqhubekayo kwe-NRF2 kukholelwa ukuba kungunobangela womhlaza wemiphunga kubantu abatshayayo. I-Nrf2 overexpression inokubangela ukuba iiseli ezinomhlaza zingazonakalisi, ngelixa ukusebenza kwe-NRF2 okwethutyana kunokuthintela iiseli ezinomhlaza ekuvuseleleni ukwenziwa kwe-toxin.
Ukongeza, ngenxa yokuba i-NRF2 overexpression inyusa amandla e-antioxidant omzimba womntu okusebenza ngaphaya kwe-redox homeostasis, oku kukonyusa ukwahlulwa kweseli kwaye kuvelise ipateni engaqhelekanga ye-DNA kunye ne-histone methylation. Oku ekugqibeleni kunokwenza i -chemotherapy kunye ne-radiotherapy zingasebenzi kakuhle kumhlaza. Ke ngoko, ukunciphisa umda ekusebenzeni kwe-NRF2 ngezinto ezinjenge-DIM, iLuteolin, i-Zi Cao, okanye i-salinomycin inokuba zilungele izigulana ezinomhlaza nangona i-Nrf2 yokunyanzeliswa kokusebenza kungathathwa njengeyona nto ibangela umhlaza. Ukusilela kwesondlo kunokuchaphazela ii-genes, kubandakanya i-NRF2. Oku kunokuba yindlela enye yokuba ukusilela kunegalelo njani kwizidumbu.
Ibindi
Ukugqithiswa kwe-Nrf2, kunokuchaphazela nokusebenza kwamalungu athile emzimbeni womntu. Ukugqithiswa kwe-NRF2 kunokukhawulela ekugqibeleni ukuveliswa kwe-insulin-efana nokukhula kwe1, okanye i-IGF-1, esesibindi, esibalulekileyo ekuhlaziyweni kwesibindi.
intliziyo
Nangona i-Nrf2 ingenakuncedo, ukugqithisa okuqhubekayo kwe-NRF2 kunokudala iziphumo ezinobungozi kwixesha elide entliziyweni, njenge-cardiomyopathy. Inkulumo ye-NRF2 inganyuswa ngamazinga aphezulu e-cholesterol, okanye ukusetyenziswa kwe-HO-1. Oku kukholelwa ukuba yisona isizathu sokuba amazinga aphezulu angama-cholesterol angabangela iimeko zempilo yengqondo.
Vitiligo
Ukugqithiswa kwe-NRF2 kuye kwabonakaliswa ukuba kuvimbele ukukwazi ukuguqulwa kwi-vitiligo njengoko kunokuthintela iTyrosinase, okanye i-TYR, isenzo esibalulekileyo ekuguqulweni kwe-melaninogenesis. Ucwaningo luye lwabonisa ukuba le nkqubo ingaba esinye sezizathu eziphambili zokuba kutheni abantu abane-vitiligo bengabonakali ukuvuselela i-Nrf2 ngokufanelekileyo njengabantu abangenayo i-vitiligo.
Kutheni i-NRF2 ingaSebenzi kakuhle
EHormesis
I-NRF2 kufuneka ivulwe ngokwe-hormetically ukuze ikwazi ukuthatha inzuzo yayo. Ngamanye amazwi, i-Nrf2 akufuneki iqalise yonke imzuzu okanye yonke imihla, ngoko ke, luluvo olukhulu ukuthatha ikhefu kuyo, ngokomzekelo, iintsuku ezi-5 ngeentsuku ezi-5 zokuphumla okanye yonke enye imini. I-NRF2 kufuneka kwakhona ifezekise umda othile wokuqalisa impendulo yayo ye-hormetic, apho i-stressor encinci ingenako ngokwaneleyo ukuyiqalisa.
I-DJ-1 Oxidation
Iprotheni deglycase DJ-1, okanye nje i-DJ-1, ebizwa ngokuba yi-protein ye-Parkinson, okanye i-PARK7, ngumlawuli oyintloko kunye nomtshina we-redox kwisimo somzimba. I-DJ-1 ibalulekile ekulawuleni indlela i-NRF2 enokuyenza ngayo umsebenzi wayo kwaye ivelise impendulo ye-antioxidant. Kwimeko apho i-DJ-1 iba ngaphezulu, iiseli ziya kwenza iprotheni ye-DJ-1 ingafinyeleleki.
Le nkqubo yenza ukuba ukusebenza kwe-NRF2 kuphelelwe ngokukhawuleza njengoko i-DJ-1 ibaluleke kakhulu ukugcina amanqanaba alinganiselayo we-NRF2 kwaye ikhusela ukuba iphulwe phantsi kwiseli. Ukuba ngaba iprotheni ye-DJ-1 ayikho okanye ingaphezulu, i-NRF2 ibonakaliso iya kuba yinto encinci, mhlawumbi isebenzise i-DIM okanye ezinye i-activation NRF2. I-DJ-1 ibonakaliso imele ukubuyisela isenzo se-NRF2 esingakwaziyo.
Ukugula okungapheliyo
Ukuba unesifo esingapheliyo, kuquka i-CIRS, izifo ezingapheliyo / i-dysbiosis / i-SIBO, okanye i-heavy metal build up, efana ne-mercury kunye / okanye ukusuka kwiingcambu zeengcambu, ezi zinokuthintela iinkqubo ze-NRF2 kunye nesigaba sesibini sokutshatyalaliswa. Kunokuba uxinzelelo lwe-oxidative luguqule i-NRF2 ibe yi-antioxidant, i-NRF2 ayiyi kubangela kwaye uxinzelelo lwe-oxidative lunokuhlala kwiseli kwaye lubangele umonakalo, oku kuthetha ukuba akukho mpendulo ye-antioxidant. Esi sisizathu esibalulekileyo sokuba kutheni abantu abaninzi abane-CIRS benovelwano oluninzi kwaye bafikelele kwizinto ezininzi. Abanye abantu bakholelwa ukuba banokuba nempendulo ye-herx, nangona kunjalo, le ndlela yokusabela inokuba yonakalisa iiseli kude.
Ukunyanga izifo ezingapheliyo, nangona kunjalo, kuya kuvumela isibindi ukuba sikhuphe i-toxins kwi-bile, ngokuthe ngcembe siphuhlise impendulo ye-hormetic ye-activation ye-NRF2. Ukuba i-bile ihlala inetyhefu kwaye ayikhutshwanga emzimbeni womntu, iya kuphinda ivuselele uxinzelelo lwe-oxidative ye-NRF2 kwaye ibangele ukuba uzive ubi nakakhulu xa iphinda ihlanjululwe kwi-gastrointestinal, okanye i-GI, iphecana. Ngokomzekelo, i-ochratoxin A inokuvala i-NRF2. Ngaphandle kokunyanga ingxaki, i-histone deacetylase inhibitors inokuthintela ukusabela kwe-oxidative ukusuka kwizinto ezininzi ezibangela ukusebenza kwe-NRF2 kodwa kunokuthintela i-NRF2 ekubeni ibangele - ngokuqhelekileyo, enokuthi ekugqibeleni isilele ukukhonza injongo yayo.
I-Fish Oil Dysregulation
I-Cholinergics yizinto ezikhuthaza i-acetylcholine, okanye i-ACh, kwaye i-choline ebuchosheni ngokunyuka kwe-ACh, ngokukodwa xa ikhubaza ukuwa kwe-ACh. Izigulane ezine-CIRS zihlala zifumana iingxaki ngokuchithwa kwamanqanaba e-acetylcholine emzimbeni womntu, ingakumbi kwingqondo. Ioli yeentlanzi ivuselela i-NRF2, isebenzise indlela yayo yokukhusela i-antioxidant ngaphakathi kweeseli.
Abantu abanezigulo ezinganyangekiyo banokuba neengxaki zoxinzelelo lwengqondo kunye ne-acetylcholine excitotoxicity, ukusuka ekuqokelelekeni kwe-organophosphate, enokubangela ukuba i-oyile yeentlanzi idale ukudumba emzimbeni womntu. Ukusilela kweCholine ukongeza ukusebenza kwe-NRF2. Kubandakanya i-choline kwisidlo sakho, (i-polyphenols, amaqanda, njl. Njl.) Inokunceda ekuphuculeni iimpembelelo ze-cholinergic dysregulation.
Yintoni eyehlisa i-NRF2?
Ukunciphisa i-NRF2 ukugqithisa kakhulu kukulungele abantu abanomhlaza, nangona kunokuba luncedo kwiintlobo zeminye imiba yempilo.
Ukutya, iziNcediso, kunye namayeza aqhelekileyo:
Apigenin (amanani aphezulu)
Brucea javanica
Chestnuts
I-EGCG (iindleko eziphezulu zanda iNRF2)
Fenugreek (Trigonelline)
UHiba (Hinokitiol / ?-thujaplicin)
Isidlo seTyuwa esiphezulu
I-Luteolin (i-Celery, i-pepper eluhlaza, i-parsley, i-perilla leaf, kunye ne-chamomile tea - i-dose ephezulu iyakwandisa i-NRF2-40 mg / kg luteolin kathathu ngeveki)
I-Metformin (ukungadliyo okungapheliyo)
I-N-Acetyl-L-Cysteine (i-NAC, ngokuthintela impendulo ye-oxidative, i-doses ephezulu)
I-Orange Peel (i-polymethoxylated flavonoids)
I-Quercetin (amanani aphezulu anganyusa iNRF2 - 50 mg / kg / d quercetin)
Salinomycin (iziyobisi)
I-retinol (yonke i-ac retinoic acid)
I-Vitamin C xa idibene neQuercetin
I-Zi Cao (i-Purple Gromwel i-Shikonin / i-Alkannin)
Iindlela kunye nezinye:
Bach1
ukubheja
Biofilms
Brusatol
Camptothecin
DNMT
DPP-23
EZH2
I-Glucocorticoid I-Receptor ukusayinwa (i-Dexamethasone ne-Betamethasone kunye)
I-GSK-3? (ingxelo elawulayo)
Kusebenze kwe-HDAC?
Halofuginone
I-Homocysteine (i-ALCAR ingakwazi ukuguqula le homocysteine yenza amazinga aphantsi a-NRF2)
IL-24
Keap1
MDA-7
I-NF? B.
I-Ochratoxin A (i-aspergillus neepeniciclium species)
Leprothemia ye-Promyelocytic
p38
p53
p97
I-alpha receptor alpha
Selenite
SYVN1 (Hrd1)
STAT3 inhibition (njenge-Cryptotanshinone)
I-Testosterone (kunye ne-Testosterone propionate, nangona i-TP intranasally inokunyusa iNRF2)
Trecator (Ethionamide)
I-Trx1 (ngokunciphisa iCys151 eKeep1 okanye kwiCys506 kwingingqi ye-NLS yeNrf2)
Trolox
Vorinostat
Ukunqongophala kweZinc (kwenza kube nzima nakubungqondo)
Indlela ye-Nrf2 yeNtsebenzo
Uxinzelelo lwe-oxidative lubangela i-CUL3 apho i-NRF2 esuka ku-KEAP1, inhibitor engafanelekanga, ingena kwinucleus yale seli, ivuselela ukubhalwa kwe-ARE, ijika i-sulfuridi ibe yi-disulfide, ibe iguqula ibe yi-geneticidants genes, ekhokelela ekuphuculweni kwe-antioxidants, njenge-GSH, i-GPX, i-GST, i-SOD, njl. Ezinye ezinye ziyakubonwa kwiluhlu olungezantsi:
Ukwandisa i-AKR
U kwandisa
Ukwandisa i-ATF4
Ukwandisa iBcl-xL
Ukwandisa iBcl-2
Ukwandisa iBDNF
Ukwandisa i-BRCA1
Ukwandisa c-Juni
Ukwandisa iCAT
Ukwandisa iCGMP
Ukwandisa i-CKIP-1
Ukwandisa i-CYP450
Ukwandisa iCul3
Ukwandisa i-GCL
Ukwandisa i-GCLC
Ukwandisa i-GCLM
Ukwandisa i-GCS
Ukwandisa i-GPx
Ukwandisa i-GR
Ukwandisa i-GSH
Ukwandisa i-GST
Ukwandisa iHIF1
Ukwandisa i-HO-1
Ukwandisa iHQO1
Ukwandisa i-HSP70
Ukwandisa i-IL-4
Ukwandisa i-IL-5
Ukwandisa i-IL-10
Ukwandisa i-IL-13
Ukwandisa i-K6
Ukwandisa i-K16
Ukwandisa i-K17
Ukwandisa iMEH
Ukwandisa uMnup2-5
Ukwandisa iNADPH
Ukwandisa i-Notch 1
Ukwandisa iNQO1
Ukwandisa iPARAR-alpha
Ukwandisa iPrx
Ukwandisa i-p62
Ukwandisa i-Sesn2
Ukwandisa i-Slco1b2
Ukwandisa i-sMafs
Ukwandisa i-SOD
Ukwandisa iTrx
Ukwandisa iTxn (d)
Ukwandisa UGT1 (A1 / 6)
Ukwandisa iVEGF
Iyanciphisa i-ADAMTS (4 / 5)
Iyancipha i-alpha-SMA
Iyancipha i-ALT
Iyancipha i-AP1
Iyanciphisa i-AST
Iyanciphisa iBach1
Iyancipha i-COX-2
Iyanciphisa i-DNMT
Iyancipha iFASN
Iyancipha iFGF
Iyanciphisa i-HDAC
Yehlisa i-IFN-?
Iyanciphisa i-IgE
Iyanciphisa i-IGF-1
Iyancipha i-IL-1b
Iyancipha i-IL-2
Iyancipha i-IL-6
Iyancipha i-IL-8
Iyancipha i-IL-25
Iyancipha i-IL-33
Iyancipha iNOS
Iyancipha i-LT
Iyanciphisa i-Keap1
Iyanciphisa i-MCP-1
Iyanciphisa iMIP-2
Iyanciphisa i-MMP-1
Iyanciphisa i-MMP-2
Iyanciphisa i-MMP-3
Iyanciphisa i-MMP-9
Iyanciphisa i-MMP-13
Iyanciphisa iNfkB
Iyancipha NO
Iyanciphisa i-SIRT1
Iyanciphisa i-TGF-b1
Iyanciphisa i-TNF-alpha
Iyanciphisa iTyr
Iyancipha i-VCAM-1
I-encoded kwi-gene NFE2L2, i-NRF2, okanye i-2 enxulumene ne-2 yenkampani ye-nerythroid, iyinqobo ye-leucine, okanye i-bZIP, i-superfamily esebenzisa iKap'n'Collar, okanye i-CNC isakhiwo.
Ikhuthaza ama-enzymes e-nitric, i-biotransformation enzymes, kunye ne-xenobiotic abathumeli bezithuthi.
Ngumlawuli obalulekileyo xa kusenziwa isigaba sesibini se-antioxidant kunye ne-detoxification enzyme genes, ekhusela iiseli kumonakalo obangelwe yi-oxidative stress kunye ne-electrophilic attack.
Ngeemeko ze-homeostatic, i-Nrf2 isetyenziswe kwi-cytosol ngokuqhotyoshelweyo komzimba we-N-terminal domain ye-Nrf2, okanye iprotheni ehlobene ne-Kelch-e-ECH okanye i-Keap1, ebizwa ngokuba yi-INrf2 okanye i-Inhibitor ye-Nrf2, yokuvimbela ukusetyenziswa kwe-Nrf2.
Inokuphinda ilawulwe yi-mammalian selenoprotein thioredoxin ukunciphisa i-1, okanye i-TrxR1, esebenza njengomlawuli ongekho.
Xa bexhatshazwa kwi-electrophilic stressors, i-Nrf2 idibanisa ne-Keap1, idlulisela kwinucleus, apho i-heterodidize idilesi yeprotheni elawulayo.
Ukusebenzisana rhoqo kunokubandakanya kunye nalawo asemagunyeni okubhalwa kwirejista uJun noFos, ezinokuba ngamalungu eproduct yentsapho yeprotini yezinto ezibhaliweyo.
Emva kokunciphisa, ezi zinkimbinkimbi zibophezela kwizinto eziphendulayo ze-antioxidant / electrophile / ARE / EPRE kwaye zisebenzise ukubhalwa kwephepha, njengoko kunjalo kwiinkomfa zakwaJun-Nrf2, okanye ukucima umbhalo, kufana ne-Fos-Nrf2.
Ukumiswa kwe-ARE, ekhutshwe okanye evinjelwe, iya kugqiba ukuba yeyiphi i-gene elawulwa ngodluliselo ngolu hlobo.
NINI ikhutshwa:
Ukusebenza kwe-thesynthesis ye-antioxidants iyakwazi ukukhupha i-ROS njenge-catalase, superoxide-dismutase, okanye i-SOD, GSH-peroxidases, GSH-reductase, GSH-transferase, NADPH-quinone oxidoreductase, okanye i-NQO1, inkqubo yeCytochrome P450 monooxygenase, thioredoxin, reductase, kunye ne-HSP70.
Ukusetyenziswa kwale synthase ye-GSH kuvumela ukukhula okuqaphelekayo kwenqanaba le-intracellular ye-GSH, ekhuselayo.
Ukongezwa kwale nxalenye kunye namazinga e-phase II enzymes efana ne-UDP-glucuronosyltransferase, i-N-acetyltransferases kunye ne-sulfotransferase.
Ukugqitywa kwe-HO-1, eyona mvume yokukhusela ekhuselekileyo yokukhula kwe CO, ngokubambisana ne-NO ivumela ukuba i-vasodilation yamaseli esicchem.
Ukunciphisa i-iron overload ngokusebenzisa i-ferritin ephakamileyo kunye ne-bilirubin njenge-lipophilic antioxidant. Zombili iiprotheni zesigaba II kunye ne-antioxidants ziyakwazi ukulungisa uxinzelelo olungapheliyo lwe-oxidative kunye nokuvuselela inkqubo eqhelekileyo ye-redox.
I-GSK3? phantsi kolawulo lwe-AKT kunye ne-PI3K, i-phosphorylates Fyn ekhokelela kulwakhiwo lwenyukliya lwe-Fyn, ethi i-Fyn phosphorylates i-Nrf2Y568 ikhokelele kuthumelo lwenyukliya kunye nokonakaliswa kwe-Nrf2.
I-NRF2 iphinda inciphise impendulo ye-TH1 / TH17 kwaye ivuselele impendulo ye-TH2.
Ii-inhibitors ze-HDAC zenze indlela yokubonakalisa iNrf2 kwaye ilawulwa phezulu ukuba i-Nrf2 iinjongo eziphantsi kwe-HO-1, i-NQO1, kunye ne-glutamate-cysteine ligase i-catalytic subunit, okanye i-GCLC, ngokukhupha i-Keap1 nokukhuthaza ukuhlukana kwe-Keap1 ukusuka kwi-Nrf2, i-Nrf2 i-transplant nuclear, ne-Nrf2 -AHA ebophayo.
I-Nrf2 ibandakanya isigxina-ubomi malunga nemizuzu ye-20 phantsi kweemeko ezisisiseko.
Ukunciphisa i-IKK? ichibi ngeKeap1 yokubopha kunciphisa I? B? Ukuthotywa isidima kwaye kunokuba yindlela engafunekiyo apho ukwenziwa kwe-Nrf2 kungqineke kuthintela ukwenziwa kwe-NF?
I-Keap1 ayisoloko idityaniswe ukuba i-NRF2 isebenze, njenge-chlorophyllin, blueberry, ellagic acid, i-astaxanthin kunye ne-tea polyphenols inokukhuthaza i-NRF2 kunye ne-KEAP1 kwi-400 ipesenti.
I-Nrf2 ilawula kakubi ngekota ye-stearoyl CoA desaturase, okanye i-SCD, ne-citrate lyase, okanye i-CL.
Genetics
KEAP1
Rs1048290
I-C allele - ibonakalise umngcipheko omkhulu kunye nefuthe elikhuselekileyo lokulwa nesifo sokuxhatshazwa kwezilwanyana (DRE)
rs11085735 (Ndiyi-AC)
idibene nenqanaba lokunciphisa ukusebenza komphunga kwi-LHS
MAPT
Rs242561
I-Tlele - ukukhusela i-Parkinsonian disorders-yayinamandla ngakumbi kwi-NRF2 / sMAF yokubopha kwaye yahlanganiswa namazinga aphezulu e-MAPT mRNA kwimimandla eyahlukeneyo ye-MAPT, kubandakanya i-cerebellar cortex (CRBL), i-cortex ye-tempte (i-TTX), into ebomvu ye-intralobula (i-WHMT)
NFE2L2 (NRF2)
rs10183914 (Ndiyi-CT)
T allele - ukwandiswa kwamanqanaba eprotheni ka-Nrf2 kunye nokulibazisa iminyaka yokuqalisa kweParkinson ngeminyaka emine
rs16865105 (Ndiyi-AC)
I-C allele - yayinobungozi obukhulu beZifo ze-Parkinson
rs1806649 (Ndiyi-CT)
I-C allele - sele ichongiwe kwaye ingaba ifanelekile kwi-etiology yomhlaza webele.
edibene nomngcipheko ophezulu wokwamkelwa esibhedlele ngexesha lamazinga aphezulu e-PM10
rs1962142 (NdingumGG)
I-allele - yayinxulumene nenqanaba eliphantsi le-cytoplasmic NRF2 ibinzana (P = 0.036) kunye ne-negative sulfiredoxin ibinzana (P = 0.042)
I-protected-left-protected from blood circulation (FEV) yokunciphisa (ukunyanzeliswa komthamo wokuphefumula kwesibini) ngokumalunga nesimo sokubhema ugwayi (p = 0.004)
rs2001350 (ndingumTT)
I-Tlele-protected-protected from FEV decline (ukunyanzeliswa komthamo wokuphefumula ngomzuzwana omnye) ngokumalunga nesimo sokubhema ugwayi (p = 0.004)
rs2364722 (NdingumAA)
Ikhuseleke ngokukhawuleza ukusuka kwi-FEV yokunciphisa (ukunyanzeliswa kwevolumu yokuphefumula kwesibini) ngokumalunga nesimo sokubhema ugwayi (p = 0.004)
Rs2364723
I-C iphela-inxulumene nokunciphisa kakhulu i-FEV kubantu baseJapan abanomdlavuza wamaphaphu
Rs2706110
G allele - ubonise umngcipheko omkhulu kunye nesiphumo esikhuselekileyo sokulwa nesifo sokuxhatshazwa kwezidakamizwa (DRE)
I-AA alleles - ibonise kakhulu incitshiso ye-KEAP1
I-AA alleles - idibene nomngcipheko wokwanda komhlaza wesibeleko (P = 0.011)
rs2886161 (ndingumTT)
I-allele - ehambelana neZifo ze-Parkinson
Rs2886162
I-allele-yayinxulunyaniswa nentetho ephantsi ye-NRF2 (P = 0.011; OKANYE, 1.988; CI, 1.162-3.400) kunye ne-AA genotype yayinxulumene nokuphila okungalunganga (P = 0.032; HR, 1.687; CI, 1.047 2.748)
rs35652124 (ndingumTT)
I-allele-ehambelana nephezulu ehambelana nobudala ekuqaleni kweSifo se-Parkinson vs G allele
I-C allele - inyuse iprotheni ye-NRF2
I-allele - yayineeprotheni ezingaphantsi kwe-NRF2 kunye nomngcipheko omkhulu wesifo senhliziyo kunye noxinzelelo lwegazi
rs6706649 (Ndiyi CC)
I-C allele - yayineeprotheni ezisezantsi ze-NRF2 kwaye yandisa ingozi yeZifo ze-Parkinson
rs6721961 (NdingumGG)
I-allele - yayineprotheni ephantsi yeNRF2
I-TT ithobela - umbutho phakathi kokubhema ugwayi kwi-smoking smokers kunye nokunciphisa izinga lomzimba
I-TT allele - yayinxulumene nomngcipheko wokwanda komhlaza webele [P = 0.008; OKANYE, 4.656; ixesha lokuzithemba (CI), 1.350�16.063] kunye ne-T allele idibaniswe nomlinganiselo ophantsi we-NRF2 inkcazo yeprotheni (P = 0.0003; OKANYE, 2.420; CI, 1.491�3.926) kunye ne-SRXN1 ibonakaliso (P = 0.047; 1.867; CI = 1.002�3.478)
I-allele - allele yadibaniswa ngokuchanekileyo ne-ALI ehlobene ne-28-day-mortality emva kwe-syicrome
I-Tlele-protected-protected from FEV decline (ukunyanzeliswa komthamo wokuphefumula ngomzuzwana omnye) ngokumalunga nesimo sokubhema ugwayi (p = 0.004)
G allele - enxulumene nomngcipheko ophezulu we-ALI olandela ingxaki enkulu kwi-Yurophu nase-Afrika-yaseMelika (umlinganiselo we-OR, X ORUMX; 6.44%
I-AA alleles - ehambelana nesifo sesifuba esisisifo
I-AA alleles - ibonakaliswe kakhulu ekunciphiseni imbonakalo ye-NRF2 yesimo somzimba kwaye ngenxa yoko, ingozi enkulu yomdlavuza wamaphaphu, ngakumbi abo babesolo
I-AA alleles - inomngcipheko ophezulu kakhulu wokuphuhlisa i-T2DM (OKANYE 1.77; 95% CI 1.26, 2.49; p = 0.011) ngokumalunga nalabo abane-CC genotype
I-AA ixhomekeke-inxulumano oluqilileyo phakathi kokulungiswa kwelinxeba kunye nobutshanje obunokutsha kweemitha-mlilo (ezinxulumene nomngcipheko ophezulu kakhulu wokuphuhlisa imiphumo emfutshane kwi-Afrika-baseMerika ngokuhamba kwiCaucasians)
ezinxulumene nomlomo we-estrogen unyango kunye nomngcipheko we-thromboembolism eneengqungquthela kubasetyhini abasemva
rs6726395 (Ndingum AG)
Ukhuselo olukhuselekileyo ukusuka kwi-FEV1 ukwehla (ukunyanzela umthamo wokuphefumula kwesibini) ngokumalunga nesimo sokubhema ugwayi (p = 0.004)
I-allele-ehambelana nokunciphisa kakhulu i-FEV1 kubantu baseJapan abanomdlavuza womphunga
I-GG alleles - yayinezinga eliphezulu leNRF2 kwaye iyancipha umngcipheko wokuhlaselwa kwe-macular
I-GG alleles - yayinomdla ophezulu kunye neCholangiocarcinoma
rs7557529 (Ndiyi-CT)
I-C iphela-ehambelana nezifo ze-Parkinson
Uxinzelelo lwe-oxidative kunye nezinye izixinzelelo zingabangela umonakalo weseli ekugqibeleni ekukhokelela kwimibandela yezempilo. Uphando luye lwabonisa ukuba ukusebenza kwe-Nrf2 kunokukhuthaza umzimba wokhuselo lomzimba wokukhusela i-antioxidant, nangona kunjalo, abaphandi baye baxubusha ukuba i-Nrf2 ukugqithisa ingxaki inokuba neyona mngcipheko omkhulu kwimpilo kunye nokuphila kakuhle. Iindidi ezahlukahlukeneyo zomhlaza zingenzeka kwakhona nge-Nrf2 yokuqhekeza.
UDkt Alex Jimenez DC, i-CCST Insight
I-Sulforaphane kunye neZiphumo zayo kuMhlaza, ukusweleka, ukuGuga, uBongo kunye nokuziphatha, isifo sentliziyo kunye nokunye
VIDEO
I-Isothiocyanates zizinye zezona zibalulekileyo zityalo zezityalo onokuzifumana kwisondlo sakho. Kule vidiyo ndiyenzela iimeko ezinzulu kunazo zonke eziye zenziwa. Ukufutshane okufutshane? Dlulela kwisihloko ozithandayo ngokuchofoza enye yeengongoma zangezantsi. Umgca wexesha eliphantsi.
Amacandelo aphambili:
00: 01: 14 - I-cancer kunye nokufa
00: 19: 04 - Ukuguga
00: 26: 30 - Ubunono nokuziphatha
I-00: I-38: 06 - I-recap yokugqibela
00: 40: 27 - Dose
Umgca wexesha elipheleleyo
00: 00: 34 - Ukuqaliswa kwe-sulforaphane, ingqwalasela ephambili yevidiyo.
I-00: I-01: 14 - Ukusetyenziswa kwemifuno yeCruciferous kunye nokunciphisa kuzo zonke izizathu zokufa.
I-00: 02: 12 - Umngcipheko womhlaza we-prostate.
I-00: 02: 23 - Ingozi yomhlaza wesibeletho.
I-00: 02: 34 - Umdlavuza womlenze kwingozi yokubhema.
00: 02: 48 - Ingozi yomhlaza wesifuba.
I-00: 03: 13 - I-Hypothetical: kuthekani ukuba unomdlavuza? (ukungenelela)
I-00: I-03: 35 - Indlela engabonakaliyo yokuqhuba umhlaza kunye nokufa kwedatha yokudibanisa.
00: 04: 38 - Sulforfane nomhlaza.
I-00: 05: 32 - Ubungqina benkomo obonakalisa impembelelo enamandla ye-broccoli inhluma ehluthwayo ekuphuculweni kwe-tumor kwi-rats.
I-00: I-06: 06 - Impembelelo yokuxhaswa ngokuthe ngqo kwe-sulforaphane kwizigulane zomhlaza wesibeletho.
I-00: I-07: 09 - Ukuqokelela i-isothiocyanate i-metabolites kwimizimba yesisu.
I-00: 08: 32 - Ukuvinjelwa kweeseli zomhlaza zesisu.
00: 08: 53 - Isifundo somlando: i-brassicas yasungulwa njengezakhiwo zezempilo nakwiRoma lasendulo.
I-00: 09: 16 - I-Sulforfane ikhono lokuphucula ukwanda kwe-carcinogen (benzene, acrolein).
I-00: 09: 51 - NRF2 njengenguqu yokuguqula izakhi nge-antioxidant response elements.
I-00: 10: 10 - Indlela eyenziwa ngayo i-NRF2 isebenzise ukwanda kwe-carcinogen nge-glutathione-S-conjugates.
I-00: I-10: I-34 - i-Brussels ihluma iyakhuphula i-glutathione-S-transferase kwaye iyanciphisa umonakalo we-DNA.
I-00: 11: I-20 - i-Broccoli ihluma isiselo iphakamisa ibhenene ngaphandle kwe-61%.
I-00: I-13: I-31 - I-Broccoli ihluma i-homogenate ikwandisa i-enzymes e-antioxidant ephezulu.
I-00: I-15: 45 - Ukusetyenziswa kwemifuno yeCruciferous kunye nokufa kwesifo senhliziyo.
I-00: I-16: I-55 - i-Broccoli ihluma i-powder iphucula i-lipids yegazi kunye nesifo sengqondo senhliziyo yesifo se-2.
00: 19: 04 - Ukuqala kwecandelo lokuguga.
I-00: I-19: I-21 - I-Sulforaphane-ukutya okunomsoco kwandisa ubomi be-beetles ukusuka kwi-15 ukuya ku-30% (kwiimeko ezithile).
I-00: 20: 34 - Ukubaluleka kokuvuvuka okuphantsi kwexesha elide.
I-00: I-22: I-05 - Imifuno e-Cruciferous kunye ne-broccoli ihlumela i-powder ibonakala iyanciphisa iindidi ezahlukahlukeneyo zokumangalisa abantu.
I-00: 23: 40 - Ukuhlaziywa kwe-mid-video: umdlavuza, izigulane eziguga
I-00: I-24: I-14 - Iziphumo zemouse zibonisa ukuba i-sulfurephane inokuphucula ukusebenza kwe-immune ngexesha lokuguga.
I-00: I-25: I-18 -Sulforaphane ithuthukise ukunyuka kweenwele kwimodeli ye-mouse yokukhangela. Umfanekiso kwi-00: 26: 10.
00: 26: 30 - Ukuqala kwecandelo lobuchopho kunye nokuziphatha.
I-00: 27: 18 - Impembelelo ye-broccoli ihluma i-autism.
00: 27: 48 - Umphumo we-glucoraphanin kwi-schizophrenia.
I-00: I-28: 17 - Ukuqala kwengxoxo yokudandatheka (iindlela kunye nezifundo).
I-00: 31: 21 - Uvavanyo lweMouse usebenzisa i-10 imizekelo eyahlukeneyo yokuxinezeleka okubangelwa uxinzelelo kubonisa ukuba i-sulforaphane efana neyofana ne-fluoxetine (prozac).
I-00: I-32: I-00 - Ukufundiswa kubonisa ukungena ngokuthe ngqo kwe-glucoraphanin kwiimicebe kusebenza ngokufanayo ekukhuseleni ukudandatheka kwindlela yokuxhatshazwa kwentlalo.
I-00: I-33: 01 - Ukuqala kwecandelo lokuvelisa i-neurodegeneneration.
00: 33: 30 - Sulforaphane kunye nesifo se-Alzheimer.
00: 33: 44 - Sulforaphane kunye nesifo sikaParkinson.
00: 33: 51 - iSulforaphane nesifo sikaHongtington.
I-00: 34: I-13 - I-Sulforfane iphakamisa ama-proteins.
00: 34: 43 - Ukuqala kwecandelo lokulimala kwengqondo elibuhlungu.
I-00: I-35: I-01 - I-Sulforaphane injected ngokukhawuleza emva kwe-TBI iphucula imemori (isifundo se mouse).
I-00: 35: 55 - iSulforaphane kunye ne-plastic neuronal.
I-00: I-36: I-32 - I-Sulforfane iphucula ukufunda kwi-type II yesifo sikashukela kwiimiceba.
I-00: 37: 19 - iSulforaphane kunye ne-duchenne i-dystrophy muscular.
I-00: 37: 44 - I-Myostatin inhibition kwiiseli ze-satellite ze-muscle (in vitro).
I-00: 38: 06 - Ukuhlaziywa kwexesha elide: i-mortality kunye nomhlaza, umonakalo we-DNA, uxinzelelo lwe-oxidative kunye nokuvuvukala, i-benzene excretion, isifo se-cardiovascular, uhlobo lwesi-2 seswekile, iimpembelelo kwingqondo (ukudandatheka, autism, schizophrenia, neurodegeneration), indlela ye-NRF2.
I-00: I-40: 27 - Iingcamango zokuqikelela umthamo wamahlumela e-broccoli okanye i-sulforfane.
I-00: I-41: I-01 - i-Anecdotes xa ihluma ekhaya.
I-00: 43: 14 - Ekuphekeni kwamaqondo okushisa kunye nomsebenzi we-sulforaphane.
I-00: 43: 45 - Gut bacteria ukuguqulwa kwe-sulforaphane kwi-glucoraphanin.
I-00: I-44: I-24 - I-Supplements isebenza ngcono xa idibene ne-myrosinase esebenzayo kwimifuno.
I-00: I-44: I-56 - Amasu okupheka kunye nemifuno e-cruciferous.
00: 46: 06 - Isothiocyanates njenge-goitrogens.
Ngokwezifundo zophando, i-Nrf2, yeyona nto ibalulekileyo ekhutshelweyo eyenza ukuba iiseli zikhusele iindlela zokulwa ne-antioxidant ukuze zikhuphe ubuthi emzimbeni womntu. Ukugqithiswa kwe-Nrf2, nangona kunjalo, kunokubangela imiba yezempilo. Ubungakanani bolwazi lwethu lukhawulelwe kwi-chiropractic kunye nemiba yempilo yomgogodla. Ukuxoxa ngalo mbandela, nceda uzive ukhululekile ukubuza uGqr. Jimenez okanye uqhagamshelane nathi apha915-850-0900 .
Ikhutshwe nguDkt. Alex Jimenez
Ingxoxo yesihloko esongezelelweyo: cBuhlungu obuBuhlungu
Umqolo obuhlungu Sesinye sezona zinto zixhaphakileyo zokukhubazeka kunye neentsuku eziphosiweyo emsebenzini kwihlabathi liphela. Iimpawu ezibuhlungu zangasemva kwisizathu sesibini esiqhelekileyo sokutyelelwa kweofisi kagqirha, ngaphezulu kwenani losulelo oluphezulu lokuphefumla. Ngokumalunga neepesenti ezingama-80 zabemi baya kuba neentlungu zentlungu emva kanye ebomini babo. Umqolo sisakhiwo esintsonkothileyo esenziwe ngamathambo, amalungu, iigaments, kunye nezihlunu, phakathi kwezinye izicwili ezithambileyo. Ukwenzakala kunye / okanye iimeko ezixhonyiweyo, ezinje ngedisni , ekugqibeleni unokukhokelela kwiimpawu zentlungu. Ukulimala kwezemidlalo okanye ukulimala kwengozi yeemoto ngokuqhelekileyo kubangelwa yintlungu yokubuhlungu, kodwa ngamanye amaxesha ukuhamba kwezinto ezilula kunokuba neziphumo ezibuhlungu. Ngethamsanqa, ezinye iindlela zokhathalela unyango, ezifana nokunyamekelwa kwe-chiropractic, kunokunceda ukubuyisela intlungu emva kokusetyenziswa kwemilenze kunye nokunyanzeliswa kwemigaqo, ekugqibeleni ukuphucula intlungu.
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