I-Gastro Health Intestinal
Iqela lezonyango eliSebenzayo leKlinikhi yeGastro yamathumbu eSebenzayo. I-gastrointestinal okanye (GI) iphecana lenza okungakumbi kunokwetyisa ukutya. Inegalelo kwiinkqubo ezahlukeneyo zomzimba kunye nemisebenzi. UDkt Jimenez ujonga iinkqubo eziye zenziwa ukunceda ukuxhasa impilo kunye nomsebenzi we-GI iphecana, kunye nokukhuthaza ukulinganisela kwe-microbial. Uphando lubonisa ukuba i-1 kwi-4 abantu base-US banesisu okanye iingxaki zamathumbu ezinzima kangangokuthi ziphazamisa imisebenzi yabo yemihla ngemihla kunye nendlela yokuphila.
Iingxaki zamathumbu okanye ukugaya zibizwa ngokuba yi-Gastrointestinal (okanye i-GI) Disorders. Injongo kukufikelela kwimpilo yokwetyisa. Xa inkqubo yokwetyisa esebenza kakuhle isendleleni, kuthiwa umntu usempilweni entle. Iphecana le-GI likhusela umzimba ngokukhupha i-toxins eyahlukeneyo kunye nokuthatha inxaxheba kwiinkqubo ze-immunological okanye xa amajoni omzimba asebenzisana nama-antibodies kunye nama-antigens. Oku kudityaniswa nokuxhasa ukwetyisa kunye nokufunxa izondlo ezisuka kukutya komntu ngamnye.
by UGqr Alex Jimenez | Chiropractic, Ubuhlungu obungapheliyo, Iimeko eziPhathwayo, I-Gastro Health Intestinal, I-Gut ne-Intestinal Health, impilo, Unyango, yokuzonwabisa, I-Viscerosomatic Reflex, Ukuphila
intshayelelo
UDkt Jimenez, DC, ubonisa indlela uxhulumaniso lwe-metabolic olungapheliyo njengokuvuvukala kunye nokuxhatshazwa kwe-insulin kubangela ukusabela kwekhonkco emzimbeni kule nxalenye ye-2. Izinto ezininzi zihlala zinendima kwimpilo nakwimpilo yethu. Kwinkcazo yanamhlanje, siza kuqhubeka malunga nokuba ezi zifo ze-metabolic zichaphazela njani amalungu abalulekileyo kunye neenkqubo zamalungu. Ingakhokelela kwimiba egqithileyo yengozi ehambelana neempawu ezinjengeentlungu kwimisipha, amalungu, kunye namalungu abalulekileyo. Icandelo 1 ivavanye indlela iiprofayili zomngcipheko ezityhutyhayo ezifana nokunganyangeki kwe-insulin kunye nokudumba okuwuchaphazela ngayo umzimba kwaye kubangele izihlunu kunye namalungu iimpawu ezinjengeentlungu. Sikhankanya izigulana zethu kubaboneleli bezonyango abaqinisekisiweyo ababonelela ngonyango olufumanekayo kubantu abaneemeko ezingapheliyo ezinxulumene noqhagamshelo lwe-metabolic. Sikhuthaza isigulane ngasinye xa kufanelekile ngokuthumela kubaboneleli bezonyango abanxulumeneyo ngokusekelwe kukuxilongwa okanye iimfuno zabo. Siyayiqonda kwaye siyayamkela into yokuba imfundo yindlela engummangaliso xa sibuza imibuzo ebalulekileyo yababoneleli bethu ngokwesicelo sesigulana kunye nokuvuma. UDkt Alex Jimenez, DC, usebenzisa olu lwazi njengenkonzo yemfundo. isikhanyeli
Indlela isibindi esiNxulumaniswa ngayo neZifo zeMetabolic
Ke sinokujonga esibindini ukufumana iindlela zangaphambili zomngcipheko wentliziyo. Sinokukwenza njani oko? Ewe, masiqonde i-biochemistry yesibindi. Ngoko kwi-hepatocyte yesibindi sesibindi esinempilo, xa uye wandisa i-insulin efihliweyo ngenxa yokuba kwakukho isidlo esasifuna ukuba i-glucose ifakwe, yintoni okulindeleyo ukuba i-insulin receptor isebenza kukuba i-glucose iya kungena. Emva koko i-glucose yayiza kufumana i-oxidized kwaye yajika yaba ngamandla. Kodwa nantsi ingxaki. Xa i-hepatocyte ine-insulin receptors engasebenziyo, unayo loo insulin ngaphandle, kwaye i-glucose ayizange iyenze. Ngena. Ke into eyenzayo kukucima iasidi enamafutha, ucinga, “Madoda, akufuneki sitshise iiasidi zethu ezinamafutha. Kungene iglucose."
Ke xa i-glucose ingekho, kwaye awutshisi i-acids enamafutha, ixhaphake kakhulu ukuba abantu bazive bediniwe kuba akukho nto itshisa amandla. Kodwa nantsi i-sequela yesibini; ziya phi zonke ezo asidi ezinamafutha, akunjalo? Ewe, isibindi sinokuzama ukuwapakisha kwakhona njenge-triglycerides. Ngamanye amaxesha, bahlala kwi-hepatocyte okanye batshintshelwe ngaphandle kwesibindi ukuya egazini njenge-VLDL okanye i-lipoprotein ephantsi kakhulu. Unokuyibona njengokutshintsha kwe-triglyceride ephezulu kwiphaneli yelipid esemgangathweni. Ke, xa sonke sithetha ngokufumana inqanaba le-triglyceride ukuya malunga nama-70 njengenjongo yakho ye-8+, xa ndiqala ukubona i-triglycerides inyuka, silinda de ibeyi-150, nangona ikukunqunyulwa kweelebhu zethu. Xa siyibona kwi-150, siyazi ukuba bakhupha i-triglycerides ngaphandle kwesibindi.
Ke oko kuya kwenzeka amaxesha amaninzi ngaphambi kokuba sifumane i-glucose engasebenzi kakuhle. Ke jonga i-triglycerides yakho, ukuzila i-triglycerides, njenge-biomarker evelayo okanye yokuqala yokungasebenzi kakuhle kwe-insulin. Ngoko ke lo ngomnye umzobo othi ukuba i-triglycerides iyadalwa ngenxa yokuba i-acids enamafutha i-oxidized, inokuhlala esibindi. Ke loo nto yenza i-steatosis okanye isibindi esinamafutha, okanye zinokukhutshelwa ngaphandle, kwaye ziguquke zibe lipoprotein. Siza kuthetha ngaloo nto ngomzuzwana nje. Umzimba unje, "Siza kwenza ntoni ngala ma-acids anamafutha?" Asinakuzama ukuzityhala kwiindawo kuba akukho mntu uzifunayo. Ukuza kuthi ga ngelo xesha, isibindi sifana nokuthi, “Andizifuni, kodwa ndiza kuhlala ndinazo.” Okanye isibindi besiya kuthuthwa la mafutha anamafutha aze ancamathele kwiindonga zemithambo yegazi.
Ke ngoko imithambo yegazi kunye nemithambo ifana, “Ke, andiyifuni; Ndiza kuzifaka ngaphantsi kwe-endothelium yam. Kwaye yile ndlela ufumana i-atherogenesis. Imisipha ifana, "Andizifuni, kodwa ndiza kuthatha." Yiloo ndlela ofumana ngayo amanqatha kwizihlunu zakho. Ke xa isibindi sixinga yi-steatosis, ukudumba kwenzeka emzimbeni kwaye kuvelisa lo mjikelo wokutyisa ngaphakathi kwe-hepatocyte, ukonakalisa isibindi. Ufumana ukufa kweseli; ufumana i-fibrosis, elulwandiso nje lwento eyenzekayo xa singajongi imiba engundoqo yesibindi esinamafutha: ukudumba kunye nokunganyangeki kwe-insulin. Ke, sijonge ukunyuka okuchuliweyo kwi-AST, ALT, kunye ne-GGT; khumbula ukuba yi-enzyme esekwe esibindini.
IHormone Enzymes & Ukudumba
Ii-enzymes ze-GGT esibindini zizichongi zomsi kwaye zisixelela ukuba lungakanani uxinzelelo lwe-oxidative oluqhubekayo. Ngaba siya kujonga kwi-HSCRP kunye ne-APOB ukuze sibone ukuveliswa kwesi sibindi? Ngaba iqala ukulahla i-acids enamafutha amaninzi nge-VLDL, i-APOB, okanye i-triglycerides? Kwaye indlela ekhethwa ngayo yimfuzo nje, ngokunyanisekileyo. Ke ndikhangela abamakishi besibindi ukuba bandixelele ukuba kuqhubeka ntoni esibindini njengophawu lwento eyenzekayo kuyo yonke indawo. Kuba loo nto inokuba yindawo ebuthathaka yemfuza yomntu, abanye abantu basengozini ngokwemfuza nje ngokweprofayili zabo zelipid. Ukuza kuthi ga ngoku, sinokujonga into ebizwa ngokuba yi-metabolic dyslipidemia. Uyazi oku njenge-triglycerides ephezulu kunye ne-HDL ephantsi. Unokujonga ngokuthe ngqo umlinganiselo; ibhalansi eyiyeyona ntathu nangaphantsi. Iqala ukusuka kwisithathu ukuya kwisihlanu kwaye emva koko ezintlanu ukuya kwisibhozo, njengesibhozo siphantse sibe yi-pathognomonic yokumelana ne-insulin. Ufikelela ekubeni uxhathise i-insulin ngakumbi nangakumbi.
Njengoko inani linyuka kwi-trig phezu komlinganiselo we-HDL, leyo yindlela elula, elula yokukhusela i-insulin. Ngoku abanye abantu bajonge i-3.0 kule nto kodwa basenokumelana ne-insulin. Ngoko kukho ezinye iimvavanyo ozenzayo. Le yindlela yokufumana abo babonisa ukunganyangeki kwe-insulin ngeelipids. Kwaye khumbula, wonke umntu wahlukile. Abasetyhini abane-PCOS banokuba ne-lipids emangalisayo kodwa banokubonisa ukwanda okanye ukuncipha kwamahomoni ahambelana ne-insulin, i-estrogen, kunye nokuvuvukala. Ngoko khangela enye into ngaphandle kovavanyo olunye okanye umlinganiselo ukubonisa ukuba bayifumene na. Ujonge ukubona ukuba yeyiphi indawo apho siya kufumana khona umkhondo.
Ngoko ke masisebenzise igama elithi impilo. Umntu osempilweni uneVLDL ebonakala isempilweni eqhelekileyo kumlinganiselo oqhelekileyo emizimbeni yakhe, yaye uneLDL neHDL eqhelekileyo. Kodwa ngoku jonga into eyenzekayo xa ufumana ukuxhathisa kwe-insulin. Ezi VLDL ziqala ukumpompa ngeetriglycerides. Yiyo loo nto betyeba. Yi-lipotoxicity. Ke ukuba uqala ukujonga amanani amathathu e-VLDL kwiprofayili ye-lipoprotein, uya kubona ukuba elo nani liyarhubuluza, kwaye zininzi, kwaye ubukhulu bawo bukhulu. Ngoku nge-LDL, into eyenzekayo kukuba isixa se-cholesterol ngaphakathi nasezantsi siyafana. Ukuba ndikhupha zonke ezi bhaloni zamanzi, ngumlinganiselo ofanayo we-cholesterol ye-LDL. Nangona kunjalo, eso sixa se-LDL cholesterol ekuxhathiseni i-insulin sipakishwa kwakhona kwi-LDL encinci exineneyo.
I-Functional Medicine iyidlala njani indima yayo?
Ngoku siyaqonda ukuba kusenokubakho abanye benu abangakwaziyo okanye abangakwaziyo ukufikelela kolu vavanyo, okanye abaguli bakho abanako ukuyifikelela, yiyo loo nto siyiphendule imibuzo kwaye sijonge ezinye iindlela zokunganyangeki kwe-insulin kwaye sinyange ingcambu engunobangela okhoyo. echaphazela umzimba. Jonga iimpawu zokudumba kunye nezinye iiprofayili ezihambelanayo zokunganyangeki kwe-insulin. Inani lesuntswana liphezulu xa bexhathisa i-insulin. Ngoko i-cholesterol iyafana, ngelixa inani lamasuntswana liphezulu, kwaye i-LDL encinci exineneyo inamandla ngakumbi. Yiphathe ngenxa yokuba nokuba unakho ukufikelela ekwazini i-LDL, kufuneka kubekho into entloko yakho ethi, "Mntu, nangona i-cholesterol ye-LDL yomntu ibonakala ilungile, banetoni zokudumba kunye nokuxhathisa i-insulin; Andiqinisekanga ukuba abanalo inani eliphezulu lamasuntswana.” Usenokucinga ukuba benza oku ukuze bakhuseleke.
Enye into eyenzekayo kukumelana ne-insulin kukuba i-HDL okanye i-cholesterol esempilweni ithande ukuba ncinci. Ke akulunganga kakhulu kuba umthamo we-efflux we-HDL uyancitshiswa xa incinci. Ke siyayithanda i-HDL enkulu, ukuba uyathanda. Ukufikelela kolu vavanyo kuya kukunika isalathiso esiluqilima sento eyenzekayo ngesigulana sakho ngokwembono ye-cardiometabolic.
Xa kuziwa kolu vavanyo, kubalulekile ukuzisebenzisa ukujonga ixesha lesigulana xa sinokudumba okanye ukuxhathisa kwe-insulin emizimbeni yabo, okuchaphazela umgangatho wobomi babo. Nangona kunjalo, abantu abaninzi badla ngokuchaza ukuba olu vavanyo luyabiza kwaye luya kuhamba nomgangatho wegolide wovavanyo lokufikeleleka kwaye bakwazi ukwenza isigqibo sokuba kufanelekile ukwenza ngcono impilo kunye nempilo yabo.
Jonga iipateni zoMngcipheko weCardiometabolic
Ke xa kufikwa kwiipatheni zomngcipheko we-cardiometabolic, sijonga inkalo ye-insulin kunye nendlela enxibelelana ngayo ne-mitochondrial dysfunction ehambelana nokuxhathisa kwe-insulin kunye nokudumba. Inqaku lophando likhankanya indlela ukungasebenzi kakuhle kwemitochondrial kunokuchaphazela ngayo umzimba. Kulungile, masithethe ngomba wokuqala, ongumba wobungakanani. Enye inokuba yi-endotoxins esidibana nayo kwindawo esihlala kuyo, okanye ezimbini; inokudluliselwa ngokwemfuza ukusuka kwisizukulwana ukuya kwesinye. Ke ezi ntlobo zimbini zinokubonisa ukuba awunayo imitochondria eyaneleyo. Ngoko ke ngumba wobungakanani. Enye ingxaki ngumba womgangatho. Unazo zininzi; ayisebenzi kakuhle, ngoko ke ayinayo imveliso ephezulu okanye iziphumo eziqhelekileyo. Ngoku le nto idlala njani emzimbeni? Ke ngaphandle kwi-periphery, izihlunu zakho, i-adipocytes, kunye nesibindi, une-mitochondria kwezo seli, kwaye ngumsebenzi wabo ukunika amandla eso sitshixo kunye ne-jiggle. Ke ukuba i-mitochondria yakho ikwinani elichanekileyo, unokuninzi kokunika amandla i-insulin ye-cascade lock kunye ne-jiggle.
Inika umdla, akunjalo? Ke nantsi isishwankathelo, ukuba awunayo i-mitochondria eyaneleyo, eyingxaki kwiperiphery, ufumana uxhathiso lwe-insulin ngenxa yokuba isitshixo kunye ne-jiggle ayisebenzi kakuhle. Kodwa ukuba awunayo i-mitochondria esebenza kakuhle kwi-pancreas, ngakumbi kwiseli ye-beta, awuyikhuphi i-insulin. Ngoko usenokufumana i-hyperglycemia; awunayo imeko ephezulu ye-insulin. Xa oku kusenzeka, siyazi ukuba ingqondo yakho kufanele ukuba ibebuhlungu, kodwa ngethemba, iyakuhlangana kancinane.
Elinye inqaku likhankanya ukuba lidibanisa ukungasebenzi kakuhle kwe-mitochondrial kunye nohlobo lwesibini seswekile, kwaye ukondleka kukamama okungahambi kakuhle kunokuphambili. Lo uthetha malunga nendlela isibindi esinamafutha anxulumene ngayo ne-lipotoxicity, akunjalo? Yiyo loo nto yanda i-asidi enamafutha, kunye noxinzelelo lwe-oxidative, leyo, khumbula, yimveliso yokudumba. Ukuchithwa kwe-ATP kunye nokungasebenzi kakuhle kwe-mitochondrial. Xa oku kusenzeka, kunokusichaphazela isibindi, esithi ke sijike sibe sisibindi esinamafutha, kwaye sinokunxulunyaniswa nokungasebenzi kakuhle kwamathumbu, okukhokelela ekudumbeni okungapheliyo, ukuxhathisa kwe-insulin, ukungasebenzi kakuhle kwe-mitochondrial, kunye nokunye okuninzi. Ezi zifo zemetabolism ezingapheliyo zidibene, kwaye kukho iindlela zokunciphisa ezi mpawu zichaphazela umzimba.
isiphelo
Xa bencokola noogqirha babo, izigulana ezininzi ziyazi ukuba kwa abaqhubi abafanayo bachaphazela inkitha yezinye iiphenotypes, zonke ziqhele ukudumba, i-insulin, kunye netyhefu. Ke xa abantu abaninzi beqonda ukuba ezi zinto zingunobangela, oogqirha baya kusebenza nababoneleli bezonyango abanxulumeneyo ukuphuhlisa izicwangciso zonyango olusebenzayo lomntu. Ke khumbula, kufuneka usoloko usebenzisa umda wexesha kunye ne-matrix kuhlobo loncedo olwaziyo ukuba uqala phi ngesi sigulana, kwaye kwabanye abantu, inokuba uzakwenza kancinci indlela yokuphila kuba bonke Umsebenzi wabo kukutshintsha inani lemizimba yabo. Ngoko ke yenye yeentsikelelo amayeza asebenzayo ukuba sakwazi ukucima ukudumba emathunjini, nto leyo enceda ukunciphisa impembelelo eyityhefu umthwalo isibindi. Ikwavumela umntu ukuba afumanise ukuba yintoni esebenzayo okanye engasebenziyo ngemizimba yakhe kwaye athathe la manyathelo mancinci ukuphucula impilo yakhe.
Siyathemba ukuba unamehlo amatsha malunga nokudumba, i-insulin, kunye netyhefu kunye nendlela eyingcambu yeemeko ezininzi ezijongene nezigulana zakho. Kwaye indlela yokuphila elula kakhulu kunye nesebenzayo kunye nongenelelo lwezondlo, unokutshintsha oko kubonakaliswa kwaye utshintshe ikhondo leempawu zabo namhlanje kunye nobungozi abanabo ngomso.
isikhanyeli
by UGqr Alex Jimenez | Chiropractic, Ubuhlungu obungapheliyo, Iimeko eziPhathwayo, I-Gastro Health Intestinal, I-Gut ne-Intestinal Health, impilo, Unyango, yokuzonwabisa, I-Viscerosomatic Reflex, Ukuphila
intshayelelo
UDkt Alex Jimenez, DC, ubonisa indlela uxhulumaniso lwe-metabolic lubangela ukusabela kweketane kwizifo eziphambili ezingapheliyo kule nxalenye ye-2. Izinto ezininzi zihlala zinendima kwimpilo nakwimpilo yethu. Ingakhokelela kwimiba egqithileyo yengozi ehambelana neempawu ezinjengeentlungu kwimisipha, amalungu, kunye namalungu abalulekileyo. Icandelo 2 liza kuqhubeka nenkcazo malunga noqhagamshelwano lwe-metabolic kunye nezifo ezingapheliyo. Sikhankanya izigulana zethu kubaboneleli bezonyango abaqinisekisiweyo ababonelela ngonyango olufumanekayo kubantu abaneemeko ezingapheliyo ezinxulumene noqhagamshelo lwe-metabolic. Sikhuthaza isigulane ngasinye xa kufanelekile ngokuthumela kubaboneleli bezonyango abanxulumeneyo ngokusekelwe kukuxilongwa okanye iimfuno zabo. Siyayiqonda kwaye siyayamkela into yokuba imfundo yindlela engummangaliso xa sibuza imibuzo ebalulekileyo yababoneleli bethu ngokwesicelo sesigulana kunye nokuvuma. UDkt Jimenez, DC, usebenzisa olu lwazi njengenkonzo yemfundo. isikhanyeli
Indlela Ukuvuvukala Okuwuchaphazela Ngayo Umzimba
UGqr. Alex Jimenez, DC, unikezela: Ke apha uneseti ebhityileyo yee-adipocytes ngasekhohlo, kwaye xa ziqala ukutyeba ngobunzima beselula obuninzi, unokubona ezo macrophage, ii-boogies eziluhlaza zijikeleza zijonga, zisithi, “Heyi, kuqhubeka ntoni apha? Ayibonakali ilungile.” Ngoko bayaphanda, kwaye oku kubangela ukufa kweeseli zendawo; yinxalenye nje yokudumba kwebhola. Ke kukho enye indlela eyenzekayo apha. Ezo adipocyte azikho nje ukuba zibe manzi ngempazamo; ihlala inxulumene ne-calorie surfette. Ke oku kugqithiswa kwezondlo kuyonakalisa i-endoplasmic reticulum, okukhokelela ekudumbeni ngakumbi. Yintoni ezi seli kunye ne-adipocytes ezizama ukuyenza kukuzikhusela kwi-glucose kunye ne-lipo toxicity.
Kwaye yonke iseli, iseli ye-adipocyte, idala ezi caps zizama ukuthi, "Nceda uyeke, asinakuthatha enye i-glucose, asinakuthatha ezinye iilipids." Yindlela yokukhusela eyaziwa ngokuba kukunganyangeki kwe-insulin. Asiyonto nje eyenzekileyo. Yindlela yomzimba yokuzama ukuthintela iswekile kunye ne-lipotoxicity. Ngoku ukuba i-alamu yokuvuvukala iyenzeka ngaphezu kwe-adipocytes, ifumana inkqubo. Ezinye izicubu kunye namalungu aqala ukuva umthwalo ofanayo wekhalori surfette, ebangela ukuvuvukala kunye nokufa kweeseli. Ke i-glucose kunye ne-lipotoxicity zibukeka njengesibindi esinamafutha xa sisebenza nesibindi. Kwaye unokuba nayo kanye njengokuba isibindi esinamafutha siqhubela phambili kwi-cirrhosis ngokufa kwe-hepatocyte. Indlela efanayo eyenzekayo kwiiseli zezihlunu. Ke iiseli zethu ze-skeletal muscle zibona ngokuthe ngqo ukufa kweeseli emva kokudumba kwaye zibone ukubekwa kwamafutha.
Eyona ndlela ingcono yokucinga ngayo, umzekelo, iinkomo ezikhuliselwa ukutyiwa kunye nendlela eziye zabhatalwa ngayo. Ngoko ke loo nto yokubeka amanqatha. Kwaye ebantwini, unokucinga malunga nendlela abantu ababa ngayo i-sarcopenic njengoko besiya bexhathisa i-insulin. Yinto efanayo xa izicubu zomzimba zizama ukuzikhusela kwi-glucolipotoxicity, ebangela impendulo yendawo yokudumba. Iba yimpendulo ye-endocrine xa iqala ukujolisa kwezinye izicubu kwi-periphery, nokuba isibindi, imisipha, ithambo, okanye ingqondo; yinto nje eyenzekayo; bakwi-visceral adipocytes enokuthi yenzeke kwezinye izihlunu. Ke leyo yimpembelelo yakho yeparacrine. Kwaye ke inokuhamba yintsholongwane, ukuba uyathanda.
Ukuvuvukala okuNxulunyaniswe noKuchasa i-insulin
UGqr. Alex Jimenez, DC, unikezela: Ufumana le mpendulo yasekhaya kunye nenkqubo yepro-ukudumba edityaniswa nokuxhathisa kwe-insulin, ubuyela kule ndlela yokukhusela ngokuchasene neglucose kunye ne-lipotoxicity. Apha ubona ukuba imithambo yegazi kwimithambo yethu ibanjwa njani kwi-loop yokufaka amafutha kunye nokufa kweeseli. Ke uya kubona imithambo yegazi evuzayo kunye neediphozithi ezinamafutha, kwaye uya kubona umonakalo kunye ne-pro-atherogenesis. Ngoku, le yinto esiyichazile kwi-AFMCP yemodyuli ye-cardiometabolic. Kwaye leyo yiphysiology emva kwe-insulin receptor. Oku kwaziwa njengobuchule bokutshixa kunye ne-jiggle. Ke kuya kufuneka utshixe i-insulin kwi-insulin receptor phezulu phezulu., eyaziwa ngokuba sisitshixo.
Kwaye ke kukho i-phosphorylation cascade ebizwa ngokuba yi-jiggle ethi emva koko idale le cascade ekugqibeleni ibangele i-glucose-4 channels ukuba ivule i-glucose-4 receptors ukuba ingene kwiseli ukuze ibe yi-glucose, ethi ke isetyenziswe amandla. ukuveliswa yi-mitochondria. Ewe, ukuxhathisa kwe-insulin kulapho i-receptor ingancangathi okanye iphendule. Kwaye ke awupheleli nje ekusileleni ukufumana i-glucose kwiseli yokuvelisa amandla, kodwa unikezela ngemeko ye-hyper insulin kwi-periphery. Ke ufumana i-hyperinsulinemia kunye ne-hyperglycemia kule ndlela. Yintoni ke esinokuyenza ngaloo nto? Ewe, izondlo ezininzi zibonakaliswe ukuphucula ukutshixa kunye nokuxubha izinto ezinokuphucula i-glucose-4 abathuthi abaza beza kwi-periphery.
Izongezelelo ezichasayo eziNcincisa ukuDumba
UGqr. Alex Jimenez, DC, unikezela: Uyabona ezi zidweliswe apha: vanadium, chromium, cinnamon alpha lipoic acid, biotin, kunye nomnye umdlali omtsha, berberine. I-Berberine yibhotanical enokuthi ithobe zonke iimpawu eziphambili zokudumba. Ke yintoni eyandulela ezi zi-comorbidities rhoqo kwaye kukungasebenzi kakuhle kwe-insulin. Ewe, yintoni eyandulela ukungasebenzi kakuhle kwe-insulin amaxesha amaninzi? Ukudumba okanye ubuthi. Ke ukuba i-berberine inceda umba ophambili wokudumba, iya kujongana nokunganyangeki kwe-insulin esezantsi kunye nazo zonke izinto ezinokuthi zenzeke. Ke jonga iberberine njengokhetho lwakho. Ke kwakhona, oku kukubonisa ukuba ukuba unokunciphisa ukudumba apha phezulu, unokunciphisa iziphumo ezininzi ze-cascade ezantsi. IBerberine ibonakala isebenza ngokuthe ngqo kumaleko we-microbiome. Imodareyitha i-gut microbiota. Isenokwenza unyamezelo lwe-immune, ngoko ke ayinikezeli ukuvuvukala okuninzi.
Ke jonga i-berberine njengenye yezixhobo onokuzisebenzisa ukuxhasa ukungasebenzi kakuhle kwe-insulin kunye ne-insulin enxulumene nokuxhathisa. I-Berberine ibonakala inyusa i-insulin receptor expression, ngoko ke ukutshixa kunye ne-jiggle isebenza ngokufanelekileyo kwaye iphucule i-cascade kunye nabathuthi be-glucose-4. Le yenye indlela onokuthi ngayo uqalise ukufumana oyena nobangela weemeko ezininzi ebesixoxile ngazo xa ubona i-paracrine kunye ne-endocrine glucose toxicity, umonakalo we-lipotoxicity organ. Ngoku enye indlela omawuyithathele ingqalelo kukusebenzisa iNF kappa B. Ngoko ke injongo kukugcina iNF kappa B isekelwe kuba okoko ingafuduki, inkitha yemiqondiso yokudumba ayiqali.
Ngoko ke injongo yethu kukugcina iNF kappa B ihleli. Sinokukwenza njani oko? Ewe, sinokusebenzisa i-NF kappa B inhibitors. Ke kulo mboniso wokhetho lonyango lwazo naziphi na izinto ezidibene nokungasebenzi kakuhle kwe-insulin, zininzi iindlela zokunciphisa ezi meko zigqubanayo zichaphazela imizimba yethu. Ke unokuchaphazela ngokuthe ngqo ukunganyangeki kwe-insulin ngokusebenzisa izongezo ezichasene nokudumba okanye ngokungathanga ngqo uncede ukuxhathisa kwe-insulin okanye ukungasebenzi kakuhle kwe-insulin ngokunyusa izinto ngokuchasene nokudumba. Isizathu ukuba uyakhumbula, ukungasebenzi kakuhle kwe-insulin yinto ebangela zonke ezo zinto zidibene. Kodwa yintoni ebangela ukungasebenzi kakuhle kwe-insulin ngokuqhelekileyo kukuvuvukala okanye ityhefu. Ke injongo yethu kukujongana nezinto ezibangela ukudumba. Kuba ukuba sinokujongana nezinto ezi-pro-ukudumba kunye nokungasebenzi kakuhle kwe-insulin kwi-bud, sinokuthintela wonke umonakalo welungu elisezantsi okanye ukungasebenzi kakuhle kwamalungu.
Ukunciphisa Ukuvuvukala Emzimbeni
UGqr. Alex Jimenez, DC, unikezela: Masiqhubele phambili kwicandelo elilandelayo onokuthi unciphise okanye unciphise ukudumba kunye nomonakalo wesuphu ye-insulin ukuba uyathanda, ukuba iijini zihlamba emzimbeni. Le yile uya kuhlala uyiva kwiprizenteyishini yethu, kwaye kungenxa yokuba, eneneni, kumayeza asebenzayo, siyanceda ukulungisa amathumbu. Ngokuqhelekileyo kulapho kufuneka uye khona. Kwaye le yi-pathophysiology yokuba kutheni sisenza oko kumayeza e-cardiometabolic. Ke ukuba unokutya okungalunganga okanye okulusizi, oko kutya kwanamhlanje kwasentshona okunamafutha amabi, kuya kuyonakalisa ngqo i-microbiome yakho. Olo tshintsho kwi-microbiome lunokwenza ukwanda kwamathumbu emathunjini. Kwaye ngoku i-lipopolysaccharides inokudluliselwa okanye ivuze egazini. Ukuza kuthi ga ngelo xesha, amajoni omzimba athi, “Owu hayi mfondini. Akufanelanga ukuba ube apha." Unazo ezi endotoxins apho, kwaye ngoku kukho impendulo yokuvuvukala yasekhaya kunye nenkqubo yokuba ukudumba kuya kuqhuba ukungasebenzi kakuhle kwe-insulin, okuya kubangela ukuphazamiseka kwemetabolism ezayo emva koko.
Nokuba yeyiphi na imfuzo yomntu ethambekele kuyo, icofa kwi-epigenetically. Ke khumbula, ukuba unokukuphelisa ukudumba kwi-microbiome, oku kuthetha ukuba wenze le microbiome inonyamezelo kwaye yomelele, unokunciphisa ithowuni yokukrala yomzimba wonke. Kwaye xa unciphisa oko, kubonisiwe ukuba ibeka ubuntununtunu be-insulin. Ke okukhona usezantsi ukudumba, kokukhona kunyuka uvakalelo lwe-insulin olunxulumene ne-microbiome. Okothusayo, kubonisiwe ukuba iiprobiotics zinxulunyaniswa nokuphuculwa kobuntununtunu kwi-insulin. Ngoko iiprobiotics ezifanelekileyo ziya kudala ukunyamezela komzimba. Amandla e-Microbiome kunye nokumodareyitha kwenzeka ngeeprobiotics. Ke ngoko ubuntununtunu be-insulin bugciniwe okanye bufunyanwa kwakhona ngokusekwe kwindawo okuyo. Ke nceda uqwalasele oko njengenye indlela engathanga ngqo okanye ukhetho lonyango lokuphucula impilo ye-cardiometabolic kwizigulana.
Probiotics
UGqr. Alex Jimenez, DC, unikezela: Ke xa kufikwa kwiiprobiotics, siya kuzisebenzisa kumntu onokuthi ngaxeshanye abe nesifo samathumbu esicaphukisayo okanye aleji yokutya. Singakhetha iiprobiotics ngaphezu kwe-NF kappa B inhibitors ukuba nazo zinemiba yokumelana ne-insulin. Kodwa ukuba baneengxaki ezininzi ze-neurocognitive, sinokuqala nge-NF kappa B. Ngoko ke, yindlela onokuthi ukhethe ngayo. Ngoku, khumbula, xa uthetha nezigulana, kubalulekile ukuxoxa ngendlela ukutya kwazo okubangela ngayo ukudumba emizimbeni yazo. Kukwabalulekile ukuqaphela ukuba ayiyoncoko nje esemgangathweni; yincoko yobuninzi kunye nencoko yomzimba.
Oku kukukhumbuza ukuba xa ulungisa amathumbu ngokuwondla kakuhle kunye nokunciphisa ithoni yayo yokuvuvukala, ufumana inkitha yezinye izibonelelo zokuthintela; uyeka okanye ubuncinci ukunciphisa amandla okungasebenzi. Kwaye uyayibona loo nto, ekugqibeleni inokunciphisa umngcipheko wokutyeba, isifo seswekile, kunye nesifo se-metabolic. Sizama ukuqhubela ekhaya ukuba i-endotoxemia ye-metabolic, okanye ukulawula nje i-microbiome, sisixhobo esinamandla sokunceda izigulana zakho ezinganyangekiyo kwi-insulin okanye i-cardiometabolic. Idatha eninzi isixelela ukuba asinakwenza nje incoko malunga nokutya ngokufanelekileyo kunye nokwenza umthambo.
Kungaphezulu koko. Ke okukhona sinokuphucula i-gut microbiota, sinokutshintsha imiqondiso yokudumba ngokutya okufanelekileyo, umthambo, ukulawula uxinzelelo, ukulala, zonke ezinye izinto ebesithetha ngazo, kunye nokulungisa iintsini namazinyo. Okukhona ukudumba kuncinci, kokukhona ukungasebenzi kakuhle kwe-insulin kwaye, ngenxa yoko, iyancipha zonke ezo ziphumo zesifo esisezantsi. Ke into esifuna ukuqiniseka ukuba uyazi kukuya emathunjini kwaye uqiniseke ukuba i-microbiome yamathumbu iyonwabile kwaye iyanyamezela. Yenye yeendlela ezinamandla zokuphembelela impilo ye-cardiometabolic phenotype. Kwaye ngaphandle, nangona yayiyinto enkulu kwishumi leminyaka eyadlulayo, ii-sweeteners ezenziwe nge-caloric zenza njengoko zisenokungabi yi-caloric. Kwaye ke abantu banokukhohliswa ukuba bacinge ukuba yi-zero yeswekile.
Kodwa nantsi ingxaki. Ezi sweeteners ezenziweyo zinokuphazamisana nokuqamba kwe-microbiome esempilweni kwaye zenze uhlobo olungakumbi lweephenotypes ezimbini. Ke, nangona ucinga ukuba ufumana inzuzo ngaphandle kweekhalori, uya kwandisa umngcipheko wesifo seswekile ngempembelelo yaso kwi-gut microbiome. Kulungile, siphumelele kwinjongo yokuqala. Ngethemba, uye wafunda ukuba i-insulin, ukuvuvukala, i-adipokines, kunye nazo zonke ezinye izinto ezenzeka kwimpendulo ye-endocrine zichaphazela amalungu amaninzi. Ke ngoku makhe siqale ukujonga iimpawu zomngcipheko ezivelayo. Kulungile, sithethe kancinci nge-TMAO. Kwakhona, oko kusengumbono ofanelekileyo apha ngamathumbu kunye nokumelana ne-insulin. Ke sifuna ukuqiniseka ukuba ujonga i-TMAO hayi njengesiphelo sonke kodwa njengenye i-biomarker esakhulayo enokunika umkhondo malunga nempilo ye-microbiome ngokubanzi.
Ukukhangela iimpawu zokukrala
UGqr. Alex Jimenez, DC, unikezela: Sijonge kwi-TMAO ephakamileyo ukunceda isigulane siqonde ukuba sitshintshe indlela yokutya. Uninzi lwexesha, sinceda izigulana zokunciphisa iiprotheyini zezilwanyana ezingenampilo kunye nokwandisa izondlo ezisekelwe kwizityalo. Ngokuqhelekileyo bangaphi oogqirha abayisebenzisayo kunyango oluqhelekileyo. Kulungile, ngoku enye i-biomarker evelayo, kulungile, kwaye kuvakala kuhlekisa ukuyibiza ngokuba iyavela kuba ibonakala icacile, kwaye yi-insulin. Umgangatho wethu wokunyamekela uphakathi kwi-glucose, i-glucose yokuzila, kwi-postprandial glucose yethu ye-A1C njengomlinganiselo weglucose. Siyi-glucose ephakathi kwaye sifuna i-insulin njenge-biomarker evelayo ukuba sizama ukuthintela kunye nokusebenza.
Kwaye njengoko ukhumbula, sithethile izolo ukuba i-insulin yokuzila ukutya ezantsi kwekota yokuqala yoluhlu lwakho lwereferensi ye-insulin yokuzila inokuba apho ufuna ukuya khona. Kwaye kuthi e-US, oko kuthande ukuba phakathi kwesihlanu kunye nesixhenxe njengeyunithi. Ke qaphela ukuba le yi-pathophysiology yohlobo lwesibini seswekile. Ngoko chwetheza isifo seswekile esibini sinokwenzeka ngenxa yokunganyangeki kwe-insulin; inokuthi yenzeke nakwiingxaki zemitochondrial. Ke i-pathophysiology yohlobo lwesibini seswekile inokuba kungenxa yokuba i-pancreas yakho ayikhuphi i-insulin eyaneleyo. Ke kwakhona, le yilaa 20% incinci sithetha ngayo uninzi lwabantu abafumana uhlobo lwesibini seswekile; kukunganyangeki kwe-insulin, njengoko sinokukrokrela, kwingxaki ye-insulin ephezulu. Kodwa kukho eli qela labantu elonakalise i-mitochondria, kwaye abayikhuphi i-insulin.
Ke iswekile yegazi iyanyuka, kwaye bafumana isifo seswekile esibini. Kulungile, ke umbuzo ngulo, ukuba kukho ingxaki ngeeseli ze-beta ze-pancreatic, kutheni kukho ingxaki? Ngaba i-glucose iyenyuka ngenxa yokuba izihlunu zinokumelana ne-insulin, ngoko ke azikwazi ukubamba kunye nokuzisa i-glucose? Ke ngaba sisibindi esixhathisa i-insulin esibindini esingakwaziyo ukufaka iswekile ukuze sibe namandla? Kutheni le glucose ijikeleza egazini? Yiloo nto ke le nto ithetha ngayo. Ngoko indima enegalelo, kufuneka ujonge i-adipocytes; kufuneka ujonge i-visceral adiposity. Kuya kufuneka ubone ukuba lo mntu sisisu esikhulu esityebileyo esifana ne-catalyst. Yintoni esinokuyenza ukunciphisa oko? Ngaba ukudumba kuvela kwi-microbiome?
isiphelo
UGqr. Alex Jimenez, DC, unikezela: Nkqu nezintso zinokudlala indima kule nto, akunjalo? Njengokungathi mhlawumbi intso iye yonyusa i-glucose reabsorption. Ngoba? Ngaba kungenxa yoxinzelelo lwe-oxidative olubethe kwizintso, okanye ngaba ikwi-axis ye-HPA, i-hypothalamus pituitary adrenal axis apho ufumana le mpendulo ye-cortisol kunye nale mpendulo yenkqubo ye-nervous inovelwano eyenza ukudumba kunye nokuqhuba i-insulin yegazi kwaye ukuphazamiseka kweswekile yegazi? KwiCandelo 2, siza kuthetha apha ngesibindi. Ingumdlali oqhelekileyo kubantu abaninzi, nokuba abanaso isifo sesibindi esinamafutha; sidla ngokuba ngumdlali ofihlakeleyo noqhelekileyo kubantu abanokungasebenzi kakuhle kwe-cardiometabolic. Ke khumbula, sine-visceral adiposity ebangela ukudumba kunye nokunganyangeki kwe-insulin kunye ne-atherogenesis, kwaye isibindi sifana nalo mntu ubukeleyo umsulwa ubanjwe kumdlalo weqonga. Kwenzeka ngaphambi kokuba ngamanye amaxesha i-atherogenesis iqale.
isikhanyeli
by UGqr Alex Jimenez | I-Gastro Health Intestinal, I-Gut ne-Intestinal Health
Umzimba ufuna ukutya okuphehla amafutha, amandla, ukukhula nokulungisa. Inkqubo yokwetyisa iqhekeza ukutya kube yindlela umzimba onokufunxa ngayo kwaye usebenzise amafutha. Ukutya okuqhekekileyo kungena egazini ukusuka emathunjini amancinci, kwaye izondlo zithwalwa kwiiseli kuwo wonke umzimba. Ukuqonda indlela amalungu asebenza ngayo kunye nokugaya ukutya kunokunceda ngeenjongo zempilo kunye nempilo yonke.
Inkqubo yokwetyisa
Amalungu enkqubo yokwetyisa zezi zilandelayo:
- umlomo
- I-Esophagus
- Isisu
- Pancreas
- Ibindi
- Gallbladder
- Ndibonise uthando
- Amathumbu amakhulu
- I-Anus
Inkqubo yokwetyisa iqala ngokulindela ukutya, ivuselela amadlala emlonyeni ukuba avelise amathe. Imisebenzi ephambili yesixokelelwano sokwetyisa ibandakanya:
- Ukuxuba ukutya
- Ukuhambisa ukutya ngomgudu wokwetyisa – i-peristalsis
- Ukuqhekeka kweekhemikhali zokutya kube zizinto ezincinci ezifunxayo.
Inkqubo yokwetyisa iguqula ukutya kube yeyona ndlela ilula, equka:
- IGlucose - iswekile
- Amino acids - iprotheni
- Amafutha acids - amafutha
Ukwetyisa okufanelekileyo kukhupha izondlo zokutya kunye nolwelo ukugcina impilo kunye nokusebenza ngokufanelekileyo. Izakha mzimba ziquka:
- I-carbohydrate
- Iiprotheni
- Amafutha
- iivithamini
- izimbiwa
- amanzi
Umlomo kunye nommizo
- Ukutya kucolwa ngamazinyo kwaye kumanziswe ngamathe ukuze ukuginye lula.
- Kwakhona amathe aneenzayim ekhethekileyo yemichiza eqalisa ukwahlula iicarbohydrates zibe yiswekile.
- Ukucutheka kwemisipha yommizo kuphulula ukutya ukuya esiswini.
Isisu
- Ukutya kudlula ngendandatho encinci yezihlunu ukuya esiswini.
- Ixutywa neekhemikhali zesisu.
- Isisu siyakrazula ukutya ukuze sikuqhekeze ngakumbi.
- Ukutya ke kucinezelwe kwinxalenye yokuqala yamathumbu amancinci, i i-duodenum.
Ndibonise uthando
- Kanye kwi-duodenum, ukutya kuxutywa kunye ne-enzymes yokugaya ngakumbi evela kwi-pancreas kunye inyongo ukusuka esibindini.
- Ukutya kudlula kwiindawo ezisezantsi zamathumbu amancinci, abizwa ngokuba yi ijejunum kwaye i ileum.
- Izondlo zifunxwa kwi-ileum, zifakwe kwizigidi ze-villi okanye iminwe efana nentambo eyenza ukuba kube lula ukufunxa.
- I-villus nganye iqhagamshelwe kwi-mesh ye iicapillaries, yindlela izondlo ezifunxwa ngayo egazini.
Pancreas
- I-pancreas lelinye lamadlala amakhulu.
- Ikhupha iijusi zokwetyisa kunye nehomoni ebizwa ngokuba yi-insulin.
- I-insulin inceda ukulawula umthamo weswekile egazini.
- Iingxaki ngokuveliswa kwe-insulin kunokukhokelela kwiimeko ezifana nesifo seswekile.
Ibindi
Isibindi sineendima ezininzi ezahlukeneyo ezibandakanya:
- Ukuqhawula amanqatha usebenzisa i-bile egcinwe kwi-gallbladder.
- Iiprotheni kunye neecarbohydrates.
- Izihluzi kunye neenkqubo zokungcola, amayeza, kunye neetyhefu.
- Ivelisa iswekile yamandla exeshana elifutshane kwiikhompawundi ezifana nelactate kunye neeamino acids.
Amathumbu amaninzi
- I-reservoir enkulu yee-microbes kunye neebhaktheriya eziphilileyo zihlala emathunjini amakhulu kwaye zidlala indima ebalulekileyo ekugayweni okunempilo.
- Emva kokuba izondlo zifunnyiwe, inkunkuma idluliselwa kumathumbu amakhulu okanye emathunjini.
- Amanzi ayasuswa, kwaye inkunkuma igcinwa kwi-rectum.
- Emva koko ikhutshwa emzimbeni ngombhobho.
Ukutya kweMpilo yeNkqubo yokugaya
Iindlela zokugcina inkqubo yokwetyisa kunye nenkqubo yokugaya isempilweni ziquka:
Sela Amanzi Ngakumbi
- Amanzi anceda ukuba ukutya kuhambe ngokulula kwindlela yokwetyisa.
- Izixa eziphantsi zamanzi / ukuphelelwa ngamanzi emzimbeni zizinto eziqhelekileyo zokuqunjelwa.
Yongeza iFayibha Engakumbi
- Ifayibha iluncedo ekutyiseni kwaye inceda ngokuhambisa amathumbu rhoqo.
- Dibanisa zombini ifayibha enyibilikayo nenganyibilikiyo.
- Ifayibha enyibilikayo inyibilika emanzini.
- Njengoko ifayibha enyibilikayo inyibilika, yenza ijeli enokuphucula ukwetyisa.
- Ifiber enyibilikayo inokunciphisa i-cholesterol yegazi kunye neswekile.
- Inceda umzimba wakho ukuba uphucule ulawulo lwe-glucose yegazi, enokunceda ekunciphiseni umngcipheko wesifo seswekile.
- Ifayibha engenakunyibilika ayinyibiliki emanzini.
- Ifayibha enganyibilikiyo itsala amanzi kwisitulo, isenza ukuba ithambe kwaye kube lula ukudlula ngaphandle koxinzelelo oluncinci kwizibilini.
- Ifiber enganyibilikiyo inokunceda ekukhuthazeni impilo yamathumbu kunye nokuqheleka kwaye ixhasa uvakalelo lwe-insulin olunokunceda ukunciphisa umngcipheko wesifo seswekile.
Isondlo esilungeleleneyo
- Yitya iziqhamo nemifuno yonke imihla.
- Khetha iinkozo ezipheleleyo ngaphezu kweenkozo ezigayiweyo.
- Kuphephe ukutya okucutshungulwayo ngokubanzi.
- Khetha iinkukhu kunye neentlanzi ngaphezu kwenyama ebomvu kwaye unciphise inyama esetyenzisiweyo.
- Yehlisa iswekile.
Ukutya ukutya okuneProbiotics okanye Sebenzisa iiProbiotic Supplements
- Iiprobiotics ziibhaktheriya eziphilileyo ezinceda ukulwa neebhaktheriya ezingenampilo emathunjini.
- Zikwavelisa izinto ezisempilweni ezondla amathumbu.
- Sebenzisa iiprobiotics emva kokuthatha i-antibiotics ehlala ibulala zonke iibhaktheriya emathunjini.
Yitya Ngengqondo kwaye Uhlafune Ukutya Kancinci
- Ukuhlafuna ukutya ngokucokisekileyo kunceda ukuqinisekisa ukuba umzimba unamathe awoneleyo okwetyisa.
- Ukuhlafuna ngokucokisekileyo ukutya kwenza kube lula ukufunxa isondlo.
- Ukutya kancinci inika umzimba ixesha lokwetyisa ngokucokisekileyo.
- Ikwavumela umzimba ukuba uthumele iimpawu zokuba igcwele.
Isebenza njani inkqubo yokugaya ukutya
Ucaphulo
GREENGARD, H. “Inkqubo yokwetyisa.” Uphononongo lonyaka lwefiziyoloji vol. 9 (1947): 191-224. doi:10.1146/annurev.ph.09.030147.001203
Hoyle, T. "Inkqubo yokwetyisa: ingcamango edibanisayo kunye nokusebenza." Ijenali yaseBritane yobunesi (Mark Allen Publishing) vol. 6,22 (1997): 1285-91. doi:10.12968/bjon.1997.6.22.1285
www.merckmanuals.com/home/digestive-disorders/biology-of-the-digestive-system/overview-of-the-digestive-system
www.niddk.nih.gov/health-information/digestive-diseases/digestive-system-how-it-works
Martinsen, uTom C et al. "I-Phylogeny kunye neBiological Function yeGastric Juice-Microbiological Consequences yokususa iGastric Acid." Ijenali yamazwe ngamazwe yenzululwazi yeemolekyuli vol. 20,23 6031. 29 Nov. 2019, doi:10.3390/ijms20236031
URamsay, uPhilip T, kunye noAaron Carr. "I-asidi yesisu kunye ne-digestive physiology." Iiklinikhi zoTyando zaseMntla Melika vol. 91,5 (2011): 977-82. doi:10.1016/j.suc.2011.06.010
by UGqr Alex Jimenez | LweMpilo, Probiotics
Kombucha yiti enegwele ebikho malunga neminyaka engama-2,000. Yaqala ukuthandwa eYurophu ekuqaleni kwenkulungwane yama-20. Ineenzuzo ezifanayo zempilo njengeti, izityebi kwiiprobiotics, iqulethe i-antioxidants, kwaye inokutshabalalisa ibhaktheriya eyingozi. Iintengiso zeKombucha ziyakhula kwi bangaliboni ngenxa yeenzuzo zayo zempilo namandla.
Kombucha
Ngokuqhelekileyo yenziwe ngeti emnyama okanye eluhlaza, iswekile, ibhaktheriya enempilo kunye negwele. Inencasa ngokugalela iziqholo okanye iziqhamo kwiti ngelixa ibilayo. Ibiliswa kangangeveki, xa kuveliswa iigesi, i-0.5 ekhulwini yotywala, iintsholongwane eziluncedo neacetic acid. Inkqubo yokuvundisa yenza ukuba iti isebenze kancinci. Iqulethe Iivithamini ze-B, i-antioxidants, kunye neeprobiotics, kodwa umxholo wezondlo uya kwahluka ngokuxhomekeke kwi uphawu kunye nokulungiswa kwayo.
benefits
Izibonelelo zibandakanya:
- Ukuphuculwa kokucolwa kwesisu kwinto yokuba ukuvundiswa kwenza iiprobiotics.
- Inceda kwisifo sorhudo kunye ne-irritable bowel syndrome/IBS.
- Ukususwa kwetyhefu
- Ukunyuka kwamandla
- Ukuphucula impilo ye-immune system
- Ukuhla ukusinda
- Inceda kuxinzelelo lwegazi oluphezulu
- Isifo sentliziyo
Kombucha, eyenziwe nge iti eluhlaza, iquka uncedo lwe:
Probiotics
Iibhaktheriya eziluncedo zaziwa ngokuba ziiprobiotics. Ezi probiotics ezifanayo zifumaneka kwezinye ukutya okunegwele, njengeyogathi kunye sauerkraut. Iiprobiotics zinceda ukugcwalisa amathumbu kunye neebhaktheriya eziphilileyo ezinceda ukugaya, ukunciphisa ukuvuvukala, kunye nokuvelisa iivithamini eziyimfuneko ze-B kunye ne-K. Iiprobiotics ziphucula ukunyakaza kwamathumbu kunye nokunciphisa isicaphucaphu, ukuqunjelwa, kunye nokunyanzeliswa.
Antioxidants
Izibonelelo ze-antioxidants kunye ne-polyphenols ziquka:
- Ukonyuka kwezinga le-metabolic
- Ukunciphisa uxinzelelo lwegazi
- Yehlisa i-cholesterol
- Ukuphucula ukusebenza kwengqondo
- Ukunciphisa umngcipheko wezifo ezingapheliyo - isifo senhliziyo, uhlobo lwe-2 yeswekile, kunye nomhlaza othile.
IiPropathi ezichasene neeBhaktheriya
- Inkqubo yokuvundisa ivelisa iacetic acid etshabalalisa iintsholongwane eziyingozi njengebhaktiriya ehlaselayo kunye negwele, ukuthintela usulelo.
- Impembelelo ye-anti-bacterial nayo igcina ibhaktheriya enenzuzo.
Ukukhutshwa kweSibindi
- Inokunceda ukukhupha ityhefu esibindini, oku:
- Ukuphucula impilo yesikhumba ngokubanzi
- Ukuphucula ukusebenza kwesibindi
- Yehlisa ukudumba kwesisu kunye neentlungu
- Ukuphucula ukugaya kunye nokusebenza kwesinyi
Inkxaso yePancreatic
- Inokuphucula ukusebenza kwe-pancreatic, enokunceda ukukhusela umzimba kwizifo kunye nezifo ezinjenge:
- Acidx
- Ukubetha kwesisu
- Ubungqina
- Umhlaza wePancretic
Inkxaso edibeneyo
- The iti iqulethe iikhompawundi ezifana ne-glucosamines eziye zaboniswa ukuphucula impilo edibeneyo kunye nokunciphisa intlungu edibeneyo.
- I-Glucosamines yandisa i-hyaluronic acid, i-lubricating joints, enceda ukukhusela nokuwomeleza.
Yanelisa Umnqweno weSoda
- Iintlobo ezahlukeneyo ze-flavour kunye ne-carbonation yendalo inokwanelisa umnqweno we-soda okanye ezinye iziphuzo ezingcolileyo.
I-Chiropractic yezoNyango zeChiropractic kunye ne-Functional Medicine Clinic ibandakanya izinto zonyango oludibeneyo kwaye ithatha indlela eyahlukileyo kwimpilo kunye nokuphila kakuhle.. Iingcali zithatha imbono ebanzi ngempilo yomntu, ziqonda imfuneko yesicwangciso sonyango lomntu siqu ukunceda ukuchonga oko kufunekayo ukuze ube sempilweni. Iqela liya kwenza isicwangciso esilungiselelweyo esihambelana neshedyuli kunye neemfuno zomntu ngamnye.
I-Dietitian Ichaza i-Kombucha
Ucaphulo
UCortesia, uClaudia et al. “IAcetic Acid, eyona nxalenye isebenzayo yeviniga, sisibulali-ntsholongwane se-tuberculocidal esisebenzayo.” mBio vol. 5,2 e00013-14. 25 Feb. 2014, doi:10.1128/mBio.00013-14
Costa, Mirian Aparecida de Campos et al. "Impembelelo yokutya kwe-kombucha kwi-gut microbiota kunye ne-comorbidities ehambelana nokutyeba: uphononongo olucwangcisiweyo." Ukuphononongwa okubalulekileyo kwisayensi yokutya kunye nesondlo, i-1-16. 26 Okt. 2021, doi:10.1080/10408398.2021.1995321
Gaggìa, Francesca, et al. “Isiselo seKombucha esiphuma kwiTea eziLuhlaza, eziMnyama kunye neRooibos: Uphononongo oluthelekisayo oluJonga iMicrobiology, iKhemistri kunye neAntioxidant Activity.” Izondlo vol. 11,1 1. 20 Dec. 2018, doi:10.3390/nu11010001
UKapp, uJulie M, kunye noWalton Sumner. "I-Kombucha: uphononongo olucwangcisiweyo lobungqina obubonakalayo benzuzo yempilo yabantu." Annals of epidemiology vol. 30 (2019): 66-70. doi:10.1016/j.annepidem.2018.11.001
Villarreal-Soto, Silvia Alejandra, et al. "Ukuqonda i-Kombucha Tea Fermentation: Uphononongo." Ijenali yenzululwazi yokutya vol. 83,3 (2018): 580-588. doi:10.1111/1750-3841.14068
by UGqr Alex Jimenez | Chiropractic, LweMpilo, I-Gastro Health Intestinal, I-Gut ne-Intestinal Health, impilo, I-Viscerosomatic Reflex, Ukuphila
intshayelelo
The inkqubo yomzimbaIndima 'kukuba "ngabakhuseli" bomzimba ngokuhlasela abahlaseli abangena emzimbeni, ukucoca iiseli ezindala, kunye nokwenza indawo yeeseli ezintsha ukuba zichume emzimbeni. Umzimba udinga amajoni omzimba ukuze asebenze kwaye abe sempilweni kwabaninzi izinto ezibangela imekobume umzimba uboniswa yonke imihla. Xa izinto ezibangela ukusingqongileyo zidibana nomzimba, zinokubangela izinto ezininzi eziphazamisayo ngokuhamba kwexesha kwaye zibangele amajoni omzimba ukuba ahlasele ngempazamo, iiseli eziqhelekileyo njengoko zibona njengomhlaseli wangaphandle, oko kubangela ukuba umzimba ukhule. izifo. Ezinye izinto ezibangela indalo ezifana neentsimbi ezinetyhefu zinokunxulunyaniswa nezifo ze-autoimmune ezinokuchaphazela umzimba, ezibangela ukuba iimpawu ezahlukeneyo zichaphazele umzimba. Inqaku lanamhlanje lijonga iziphumo zesinyithi ezinetyhefu emzimbeni, ukuba zichaphazela njani amajoni omzimba, kunye neendlela zokulawula ifuthe lesinyithi esinetyhefu kumajoni omzimba. Sithumela izigulana kubaboneleli abaqinisekisiweyo abaziingcali kunyango lwe-autoimmune ukunceda abantu abaninzi abanezifo ezizimelayo ezihambelana nezinyithi ezinetyhefu. Sikwakhokela izigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo sisisombululo sokubuza ababoneleli bethu imibuzo ecacileyo. UDkt Alex Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli
Iziphumo zezinyithi ezinetyhefu kuMzimba
Ngaba uziva uqaqanjelwa sisisu emathunjini akho? Ngaba unayo incasa yentsimbi ekrakra emlonyeni wakho? Kuthekani ngokufumana ukuvuvukala okuchaphazela kungekuphela nje amalungu akho kodwa amathumbu akho ngokunjalo? Uninzi lwezi mpawu luphawu olunxibelelanisa ukuba unokuba unengxaki yesinyithi esinetyhefu emzimbeni wakho. Umzimba uhlala uboniswa kwizinto ezahlukeneyo zokusingqongileyo ezichaphazela abantu abaninzi ngokuhamba kwexesha. Isenokuba kukutya okusetyenzisiweyo, indawo ahlala kuyo umntu, kunye nomsebenzi wakhe womzimba. Uphando lutyhila ukuba ungcoliseko lwentsimbi enzima olusuka kungcoliseko lokusingqongileyo lunokungena emzimbeni womntu ngeendlela ezahlukeneyo ezifana neendlela zokuphefumla, zesikhumba, nezamathumbu kwaye ziqale ukuqokelelana kumalungu ahlukeneyo. Xa umzimba uphethwe zizifo ezizimelayo ezihambelana nezinyithi ezinetyhefu, iimpawu zokudumba ziya kuqala ukuchaphazela amalungu omzimba. Ukuza kuthi ga ngelo xesha, izinyithi ezinobuthi ziya kuqalisa ukuququzelela ukusebenzisana kwazo kunye ne-immune system, ebangela ukuphuhliswa kweempawu zesifo somzimba.
Iyichaphazela Njani Inkqubo Yokhuselo Lomzimba
Ke iintsimbi ezinetyhefu ziyichaphazela njani inkqubo yomzimba yokuzikhusela, ngaloo ndlela ibangela iimpawu ezinxulumene ne-autoimmunity? Njengoko bekutshiwo ngaphambili, amajoni omzimba ngumkhuseli womzimba kwaye, xa evezwe kwiziphazamisi zokusingqongileyo ngokuhamba kwexesha, kukhokelela kuphuhliso lwezifo ezizimelayo. Kwisinyithi esinetyhefu, abantu abaninzi bahlala bevezwa kumanqanaba aphantsi esinyithi ngokutya iintlanzi kunye neshellfish (eziqulathe amanqanaba aphantsi emercury). Nangona kunjalo, xa abantu bevezwa kumanqanaba aphezulu esinyithi esinzima, izifundo zityhila ukuba izinyithi ezithile zinokuchaphazela kakhulu amajoni omzimba ngokuvuselela izicubu zemisipha ezahlukeneyo kunye nabalamli abanyibilikayo ababangela ukudumba okungapheliyo okuhambelana neentsimbi ezinzima. Ezinye ze iimpawu ezinxulumene ngesinyithi esinetyhefu ebangela ukuzimela komzimba emzimbeni kubandakanya:
- Ubungqina
- Imvakalelo ebuhlungu phantsi kwezandla okanye ezinyaweni
- Intlungu zesisu
- Ukuvutha
- intlungu Joint
- Ubuthakathaka obuthathaka
Intshayelelo Yenkqubo Yamajoni omzimba-Ividiyo
Ngaba uye wafumana ukudumba kumalungu akho? Kuthekani ngokuziva ubuthathaka kwizihlunu emqolo, ezingalweni, emilenzeni, okanye entanyeni? Okanye ngaba ubuziva ungakhululekanga ngokupheleleyo emzimbeni wakho? Uninzi lwezi mpawu ziimpawu zezifo ezizimelayo ezihambelana nesinyithi esinetyhefu. Le vidiyo ingasentla yazisa amajoni omzimba kunye nendlela adlala ngayo indima yawo emzimbeni. Xa umzimba utyhileka kwizinto ezisingqongileyo njengesinyithi esinetyhefu enzima, kunokubangela ukukhula kwezifo ezizimelayo ezinxulunyaniswa nemicimbi engapheliyo efana nokudumba kwamalungu kunye neentlungu zemisipha. Iintsimbi ezinobuthi ezinobunzima ezahlukeneyo zinokuchaphazela amanye amalungu omzimba, njengoko izifundo zityhila ukuba ezi zinyithi zahlukeneyo zinetyhefu ziyityhefu esebenzayo ebangela iziphumo ezibi empilweni emzimbeni. Xa umntu evezwe kumanqanaba aphezulu esinyithi esinetyhefu enzima, imiba engapheliyo efana nokudumba kwamalungu inokubangela iintlungu ngokuthe ngcembe ngaphandle kokuba inyangwe kwangoko. Ngethamsanqa, unyango luyafumaneka ukunceda ukulawula iimpembelelo zetsimbi eziyityhefu kumajoni omzimba anxulumene nokudumba kwamalungu.
Ukulawula iZiphumo zezinyithi ezinetyhefu kwi-Immune System
Ekubeni umzimba ubonakaliswe kwizinto ezisingqongileyo rhoqo, ukuba awuphathwa ngokukhawuleza, kunokukhokelela kwi-autoimmunity ehambelana neempawu ezingapheliyo ezifana nokuvutha kwamalungu. Ngethamsanqa, kukho iindlela zokulawula iziphumo zezinto zokusingqongileyo, njengokuthoba impembelelo yesinyithi esinetyhefu kwinkqubo yomzimba. Uphando lutyhila ukuba ukudibanisa iiminerali ezibalulekileyo kukhusela ulandelelwano lwe-DNA kumonakalo ongakumbi we-oxidative kwinkqubo yomzimba yokuzikhusela. Olunye unyango olufana nokhathalelo lwe-chiropractic lusebenzisa ukuguqulwa komgogodla kumqolo ukuchukumisa okanye ukungahambi kakuhle komgogodla kumalungu ukunciphisa ukuvuvukala okuhambelana ne-autoimmunity yensimbi enetyhefu. Ekubeni kukho iindlela ezininzi zokuthi i-autoimmunity inokuchaphazela umzimba ngokubangela indalo, iimpawu ezinxulumene ne-autoimmunity ziphathwa ngononophelo lwe-chiropractic. Ukhathalelo lweChiropractic alusebenzisi kuphela ukunyanzelwa komgogodla kodwa lunokunceda ukuphucula amajoni omzimba emzimbeni ngokunyusa ukujikeleza kwe-lymphatic fluid kunye nokukhulula imisipha eqinile ejikeleze amalunga. Ukuza kuthi ga ngoku, ivumela umzimba ukuba ukhuphe i-toxins kunye nenkunkuma esemzimbeni. Ukubandakanya unyango olufana nokhathalelo lwe-chiropractic lunokunceda ukubuyisela umzimba kwimeko yawo yokusebenza.
isiphelo
Amajoni omzimba akhusela umzimba kubahlaseli bangaphandle abangena emzimbeni. Xa kukho izinto ezibangela ukusingqongileyo ukuba umzimba ubonakaliswe kuzo, unokubeka umzimba emngciphekweni wokuphuhlisa isifo esizimelayo esihambelana neempawu ezingapheliyo ezifana nokuvutha kwamalungu. Izinto ezibangela indalo ezifana neentsimbi ezinzima zinokudibaniswa nokuvuvukala kwamalungu kwaye kubangele intlungu emzimbeni. Xa oku kusenzeka, umzimba ufumana intlungu kunye nokungasebenzi kakuhle ngenxa yamalungu avuthayo. Ngethamsanqa, unyango lwe-chiropractic lusebenzisa ukunyanzeliswa komgogodla kwi-subluxation (i-spinal misalignment) ukunciphisa ukuvuvukala kwamalungu kunye nokuphucula ukujikeleza kwe-lymphatic system. Olu nyango lunokunceda umzimba ulawule i-autoimmunity ehambelana nesinyithi esinzima kunye neempawu zabo.
Ucaphulo
Ebrahimi, Maryam, et al. "Iimpembelelo zeLead kunye neCadmium kwi-Immune System kunye nokuPhucula koMhlaza." Ijenali yeNzululwazi ngeMpilo yokuSingqongileyo kunye nobuNjineli, iSpringer International Publishing, 17 Feb. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7203386/.
Jan, Arif Tasleem, et al. "Iintsimbi ezinzima kunye neMpilo yoMntu: iMechanistic Insight kwi-Toxicity kunye ne-Counter Defense System ye-Antioxidants." I-International Journal ye-Molecular Sciences, MDPI, 10 Ngomhla wama-2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4691126/.
Lehmann, Irina, et al. "Iioni zeMetal ezichaphazela inkqubo yokugonyeka komzimba." Ioni zeMetal kwiiSayensi zoBomi, ILayibrari yeSizwe ka-US yamayeza, 2011, yentshutshiso.ncbi.nlm.nih.gov/21473381/.
Tchounwou, uPaul B, et al. "Ityhefu yeMetal enzima kunye nokusingqongileyo." I-Experientia Supplementum (2012), ILayibrari yeSizwe ka-US yamayeza, 2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC4144270/.
isikhanyeli
by UGqr Alex Jimenez | Umqolo obuhlungu, Chiropractic, Ubuhlungu obungapheliyo, LweMpilo, I-Gastro Health Intestinal, I-Gut ne-Intestinal Health, I-Viscerosomatic Reflex
intshayelelo
The inkqubo yokugaya emzimbeni inceda kwinkqubo yokwetyisa ukutya okutyayo ngumninimzi. Ukutya okugaywayo kuhamba nge-bio-transformation apho ijika ibe izondlo kwaye igcinwe kwi amathumbu, isibindi, kunye ne-gallbladder, apho ijika ibe yi-bile ukuba ikhutshwe ngaphandle kwenkqubo ukuze kuqinisekiswe inkqubo ephilileyo yokusebenza kwamathumbu kunye nomzimba. Kodwa xa izinto eziphazamisayo ezifana nemikhwa engafanelekanga yokutya okanye imiba yamathumbu qala ukuchaphazela umzimba kunye ne-gallbladder, oku kubangela iingxaki ezininzi ezinokubangela ukuba umntu abe lusizi. Oku kuchaphazela umgangatho wobomi babo kuba bejongana nemicimbi ebuhlungu emizimbeni yabo etyhutyha iiprofayili zomngcipheko ezingundoqo. Inqaku lanamhlanje lijonga i-gallbladder, indlela esebenza ngayo kunye nomzimba kunye nenkqubo ye-nervous parasympathetic, kunye nendlela ekubhekiselwa ngayo intlungu yegxalaba kunye nokungasebenzi kakuhle kwe-gallbladder. Sithumela izigulane kubaboneleli abaqinisekisiweyo abakhethekileyo kwi-gastroenterology kunye nonyango lwe-chiropractic olunceda abo banemiba echaphazela amahlombe abo kunye ne-gallbladder. Sikwakhokela izigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo sisisombululo sokubuza ababoneleli bethu imibuzo ecacileyo. UDkt Alex Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli
Yintoni I-Gallbladder?
The inkqubo yokugaya iquka umlomo, izitho zangaphakathi ukusuka kwiphecana le-GI, isibindi, i-gallbladder, kunye ne-anus, apho ukutya kudliwe, kugaywe, kwaye kukhutshwe ngaphandle komzimba ukuze kugcinwe impilo. I senyongo lilungu elincinane eligcina kwaye likhuphe inyongo ngexesha elifanelekileyo lingene emathunjini ukuze lixutywe nokutya okucoliweyo okuza kukhutshelwa ngaphandle komzimba. Eli lungu limile okweperile livuthela kwaye lijike njengebhaluni xa ligcina kwaye likhupha inyongo ngelixa linobudlelwane obuqhelekileyo kunye nemithambo-luvo kunye namahomoni anceda ukulawula i-gallbladder ngokufanelekileyo. Uphando lutyhila ukuba i-ganglia ibe yinto ekujoliswe kuyo yokubangela ukuba ihomoni ye-cholecystokinin kunye ne-nerve ye-parasympathetic inyuse okanye ithobe ukuhanjiswa kwe-neurotransmission kwi-gallbladder. Oku kubangela ukuba i-gallbladder isebenze emzimbeni.
Yeyiphi imisebenzi yayo kwiNkqubo yeNervous yeParasympathetic?
Ke yeyiphi imisebenzi eyenziwa yi-gallbladder kumzimba? Ukuqala, i inkqubo ye-nervous parasympathetic ivumela umzimba ukuba uphumle kwaye wetyise ukutya okusetyenzisiweyo ukujikwa kube zizondlo. Inkqubo ye-nervous parasympathetic ikwabonelela ngokuvuselela i-gallbladder njengoko izifundo zityhila ukuba i-gallbladder ifumana i-innervation kwinkqubo ye-nervous parasympathetic edityaniswe kwi-vagus nerve ehambisa ulwazi kumqolo kunye nengqondo. Ukugcina kunye nokukhulula i-bile kule nxalenye efana nepeyari inceda ukulawula i-gastrointestinal tract. Obu budlelwane be-causal phakathi kwe-gallbladder kunye ne-parasympathetic nerve ibalulekile kuba umzimba kufuneka wazi ukuba uyigcina nini kwaye uyikhulule nini inyongo kwi-gallbladder, okanye inokubangela imiba ethile enokwenza umonakalo omkhulu emzimbeni kwaye ichaphazele nenyongo ngokwayo.
Ngaba Uyaqaqanjelwa Ngamagxa?- Ividiyo
Ngaba ukhe waneengxaki zamathumbu ezibangela i-ache ebukhali okanye ebuhlungu emqolo okanye emacaleni? Kuthekani ngeentlungu zegxalaba ezithandabuzekayo ezibonakala ngathi aziphumi ndawo? Okanye ngaba ufumana ukudumba kwindlela yakho yokwetyisa? Uninzi lwezi mpawu ziimpawu intlungu ye-visceral-somatic ichaphazela i-gallbladder. Intlungu ye-Visceral-somatic ichazwa xa kukho umonakalo kwilungu, kwaye iqala ukuchaphazela imisipha kwindawo eyahlukileyo emzimbeni. Ividiyo engentla inika umzekelo obalaseleyo weentlungu ze-visceral-somatic kwi-gallbladder kunye negxalaba. Ngoku abantu abaninzi bayazibuza ukuba intlungu yegxalaba ngumlamli we-gallbladder njani? Ewe, ukudumba kwesibindi kunye ne-gallbladder kubangela ukuba iingcambu zemithambo-luvo zibe ne-hypersensitive kwaye zicinezeleke. Oku kukhokelela kwi iiprofayili ezidibanayo, ukubangela intlungu kwimisipha yegxalaba kwaye ihambelana nentlungu ephakathi kwe-back back.
Iintlungu eziBonelekileyo zamagxa kunye nokungasebenzi kakuhle kwe-Gallbladder
Ngoku yithi umntu uva iintlungu zamagxa; Noko ke, xa bejikeleza igxalaba, akukho ntlungu? Uphi umthombo weentlungu zegxalaba zendawo, kwaye yintoni ebangela umcimbi? Kwaye kutheni ihambelana ne-gallbladder? Oku kwaziwa ngokuba iintlungu ezibhekisiweyo, apho umthombo wentlungu ungabikho kakuhle xa ubekwe kwenye indawo. Uphando lutyhila ukuba i-gallbladder dysfunctions efana ne-cholecystitis inokunxulunyaniswa neentlungu ezibukhali ze-thoracolumbar. Kuthetha ukuthini ke oku? Kuthetha ukuba nayiphi na intlungu ebhekiswayo eyimbangela yeentlungu zegxalaba inika ingcamango yokuba kukho into engalunganga nge-gallbladder. Oku kuya kunika ulwazi oluyimfuneko xa abantu bexilongwa ngoogqirha babo.
isiphelo
Umzimba udinga inkqubo yokugaya ukuze uncede ukucubungula ukutya okudliwa ngumninimzi kunye nokukhupha inkqubo ephilileyo yokusebenza. I-gallbladder igcina kwaye ikhuphe inyongo ekutyeni okucoliweyo. Oku kuqinisekisa ukuba izondlo kunye nenyongo ziyathuthwa kwaye zigqithiselwe ngaphandle komzimba. Xa izinto eziphazamisayo zibangela imiba yamathumbu kwaye zichaphazela i-gallbladder, zinokunxulumana neengxaki ezahlukeneyo ezichaphazela umzimba. Umzekelo uya kuba yimiba ye-gallbladder ehambelana neentlungu zegxalaba. Oku kubizwa ngokuba yintlungu, evela kwilungu elichaphazelekayo kwaye lihambelana nesisipha kwindawo eyahlukileyo. Oku kunokwenza umntu azive ebuhlungu kwaye azibuze ukuba kuqhubeka ntoni ngamagxa abo xa inokuba yinto ehambelana ne-gallbladder yabo. Unyango olukhoyo lunokubonelela ngolwazi olungcono lokumisela ingxaki kunye nendlela yokunciphisa imiba.
Ucaphulo
UCarter, uChris T. "Intlungu ebuhlungu ye-Thoracolumbar ngenxa ye-Cholecystitis: i-Case Study." IChiropractic & Manual Therapy, KwiBioMed Central, nge-18 kaDisemba 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4683782/.
Jones, Mark W, et al. "I-Anatomy, isisu kunye ne-Pelvis, i-Gallbladder." Ku: StatPearls [Internet]. Isiqithi saseTreasure (FL), StatPearls Publishing, 8 Nov. 2021, www.ncbi.nlm.nih.gov/books/NBK459288/.
UMawe, uGary M., et al. "IiNerva kunye neeHormones ziyasebenzisana ukulawula umsebenzi weGallbladder." Physiology, 1 kuTshazimpuzi 1998, iijenali.physiology.org/doi/full/10.1152/physiologyonline.1998.13.2.84.
Ubungcali bezoNyango, iKliniki yaseCleveland. "I-Gallbladder: Yintoni, Umsebenzi, Indawo kunye neAnatomy." Kliniki yaseCleveland, Nge-28 kaJulayi 2021, my.clevelandclinic.org/health/body/21690-gallbladder.
isikhanyeli
by UGqr Alex Jimenez | Chiropractic, LweMpilo, I-Gastro Health Intestinal, I-Gut ne-Intestinal Health, I-Viscerosomatic Reflex
intshayelelo
Enye yeempawu ezikhethekileyo zomzimba kuxa i lungile kwaye iinkqubo ze-nervous yiba nale ntsebenziswano yonxibelelwano apho ulwazi luthuthwa ngapha nangapha kuwo wonke umzimba. Idatha idluliselwe kwingqondo kwaye amathumbu ahamba nge Iingcambu ze-nerve isasazeka kuyo yonke imisipha, izicubu, kunye nemigqaliselo elawula imisebenzi ye-motor-sensory yomzimba. Xa iingcambu zemithambo-luvo zonakele okanye xa kukho imiba yamathumbu echaphazela amalungu akwinkqubo yamathumbu okanye ukuphazamiseka kwemithambo-luvo kunokubangela ukuba umzimba ungasebenzi kakuhle kwaye kubangele eminye imiba echaphazela izihlunu emilenzeni, ezingalweni, ngasemva, nasentanyeni. Inqaku lanamhlanje lijonga ukusebenza kwe-axis ye-gut-brain, ukuba olu nxibelelwano luwunceda njani umzimba, kunye nendlela ukuphazamiseka okufana nokudumba kunye ne-dysbiosis yamathumbu kubangela iingxaki emzimbeni kunye ne-axis ye-gut-brain. Bhekisela izigulana kubaboneleli abaqinisekisiweyo, abanezakhono ezikhethekileyo kunyango lwamathumbu kubantu abanengxaki ye-dysbiosis yamathumbu kunye nokudumba okungapheliyo. Sikhokela izigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo ibalulekile ekubuzeni imibuzo eqondayo kubaboneleli bethu. UDkt Alex Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli
Ngaba i-inshorensi yam ingayihlawula? Ewe, kunokwenzeka. Ukuba akuqinisekanga, nali ikhonkco kubo bonke ababoneleli beinshorensi esibakhuselayo. Ukuba unemibuzo okanye iinkxalabo, nceda ufowunele uDkt Jimenez kwi-915-850-0900.
Ukusebenza kwe-Gut-Brain Axis
Ngaba unengxaki yokudumba emathunjini akho? Kuthekani ngokuziva udiniwe rhoqo imini yonke? Ngaba nawaphi na kumalungu akho okanye izihlunu zakho ezibuhlungu okanye uzive uqina? Uninzi lwezi zibonakaliso zokuba i-axis ye-gut-brain ichatshazelwa zizinto eziqhelekileyo oye wadibana nazo umzimba. Kukho ubungqina bokuba i-bi-directional signaling phakathi kwe-gastrointestinal tract kunye nengqondo idibene ne-vagus nerve. Uphando lophando lukhankanyile ukuba i-vagus nerve yimodyuli ye-gut-brain axis kwaye ithathwa njengeyona nto iphambili kwinkqubo ye-nervous parasympathetic ebalulekileyo ekugcineni i-homeostasis emzimbeni. I-vagus nerve inceda umzimba ngokujonga yonke imisebenzi yomzimba efana nesantya sentliziyo, iimpendulo zokugaya, iimpendulo zokhuselo lomzimba, kunye nokuthumela ulwazi lwengqondo malunga nemeko yamalungu angaphakathi. I-vagus nerve ikwabandakanyeka kwi-etiology ye-metabolic kunye nengqondo engasebenziyo / ukuphazamiseka okuhlangana nomzimba okuchaphazela izihlunu kunye namalungu angaphakathi. Uphononongo olongezelelweyo lophando luye lwabonisa ukuba i-vagus nerve ineepropathi ezichasayo eziye zavulwa kwi-axis ye-HPA kwaye ikhulule i-cortisol yehomoni emzimbeni. I-macrophages kwi-spleen yenza i-tumor necrosis factor (TNF) i-molecule enamandla yokuvelisa ukuvutha xa i-vagus nerve ivuselela imveliso ye-TNF kwi-spleen, ibangela ukuba iyancipha. Ngexesha elifanayo, inxalenye yokusinda iyanda emzimbeni.
I-Gut-Brain Axis iwunceda njani uMzimba?
Nge-bi-directional ukuba amathumbu kunye nengqondo inalo emzimbeni, kuyabonakala ukuba izinto zokusingqongileyo ezifana noxinzelelo lwe-oxidative, ukudumba, kunye nokuphazamiseka kwemeko yeemvakalelo kubangela utshintsho kwiindlela ze-glutamatergic kunye neurotrophins emzimbeni. Uphando lophando lukhankanyile ukuba i-axis ye-gut-brain inceda ukuphembelela inkqubo ye-nervous autonomic ngokuvula amajoni omzimba. Xa amajoni omzimba esebenza, umzimba unokusebenza ngokubanzi njengonyamezelo lwemisipha, unikeze ii-SCFAs ze-microbiota-derived kwi-blood-brain barrier, kwaye ulawule i-homeostasis yomzimba. Xa i-axis ye-gut-brain iqala ukungasebenzi, amajoni omzimba aya kuqala ukwandisa imveliso yawo ye-cortisol enokubangela ukuqina kwemisipha kunye ne-spasms ukuchaphazela umzimba. Xa kukho ukuvuvukala kwinkqubo yamathumbu, kunokubangela ukuba izihlunu emzimbeni zibe buthathaka, kwaye kunokuchaphazela umqolo obangela ukuba imiba yeentlungu ezisezantsi ziphuhle ngokuhamba kwexesha. Nanini na xa i-axis ye-gut-brain ichaphazeleka yimiba yokusingqongileyo, umzimba uya kuqalisa ukubangela ingxaki ngezi mpawu kwaye wenze umntu abe lusizi.
IMicrobiome ichatshazelwa kuKudumba-Ividiyo
Ngaba ufumana ukuqina kwemisipha okanye ubuthathaka kumqolo wakho ophantsi, intamo, okanye amanye amalungu omzimba? Ngaba ukhe waziva uguquguquka okanye uziva unexhala rhoqo? Uninzi lwezi mpawu udibana nazo yi-axis yobuchopho engasebenzi kakuhle echaphazela umzimba wakho. Ividiyo engentla ichaze ukuba kwenzeka ntoni xa i-gut microbiome ichatshazelwa zizinto ezivuthayo ezibangela i-dysbiosis yamathumbu kunye nokuphazamiseka kwemithambo-luvo. Uphando lophando lukhankanyile ukuba ukwakheka phakathi kwamathumbu kunye nengqondo njengoko zinxibelelana kunceda ukubumba umzimba. Xa umntu eqala ukutshintsha indlela abatya ngayo kunye nendlela abaphila ngayo, amathumbu abo awayi kuchaphazeleka kuphela, kodwa inkqubo yabo yemithambo-luvo iqala nokutshintsha. Izinto ezingafunekiyo zinokubangela ukuphazamiseka okuninzi emzimbeni kwaye, ukuba zingaphathwa ngokukhawuleza, zinokukhula zibe yimiba engapheliyo echaphazela amalunga, imisipha kunye nezicubu.
Ukuvuvukala kunye ne-Gut-Brain Dysbiosis
Xa inkqubo ye-gut-brain ichatshazelwa zizinto ezingafunekiyo, iimpawu ezahlukeneyo ziya kuqala ukunyuka emzimbeni kwaye ziqale ukonakalisa amalungu athile, izicubu, izihlunu, kunye namalungu adinga i-axis ye-gut-brain ukuze ugcine umzimba usebenza. Ayisiyiyo kuphela into enokuthi ukudumba kubangele ezi zinto zingafunwayo, kodwa i-dysbiosis yamathumbu inokuchaphazela ii-T-cells kwi-immune system. Uphando lophando lukhankanyile ukuba xa iimpawu ezivuthayo ziqala ukuhambisa iibhaktheriya ezinobungozi kumqobo we-gut-epithelial kwisithintelo segazi-ingqondo, inokuba negalelo kwi-multiple sclerosis kumqolo. Uphononongo olongezelelweyo lophando lufumene ukuba ukungasebenzi kakuhle kwamathumbu okubangelwa sistrowuku emzimbeni kuvumela ibhaktheriya e-commensal ukuba yosulele izicubu ze-peripheral, ibangele usulelo olufana nenyumoniya kunye nosulelo lomjelo womchamo. Xa abantu beqala ukufumanisa ukuba yintoni ebangela ukuba i-axis yabo ye-gut-brain ingasebenzi, banokuqala ukuphilisa imizimba yabo.
isiphelo
Amathumbu kunye neenkqubo ze-nervous zinonxibelelwano olukhethekileyo lwe-bi-directional eyaziwa njenge-axis ye-gut-brain. I-axis ye-gut-brain inceda umzimba usebenze ngokumisa amajoni omzimba kunye nokulawula i-homeostasis nge-vagus nerve. I-vagus nerve yinxalenye yenkqubo ye-nervous parasympathetic evumela wonke umsebenzi womzimba njengokubetha kwentliziyo, ukugaywa, kunye nokuphendula komzimba ngelixa uthumela ulwazi malunga nemeko yamalungu angaphakathi kwingqondo. I-vagus nerve ikwaqinisekisa ukuba amalungu angaphakathi asebenza ngokuchanekileyo. Xa izinto ezingafunekiyo zokusingqongileyo ezifana nokudumba okanye i-dysbiosis yamathumbu iqala ukuchaphazela i-axis ye-gut-brain, inokonakalisa amalungu angaphakathi kwaye ibangele ukuba umzimba ungasebenzi. Xa abantu beqaphela ukuba imizimba yabo ingasebenzi kakuhle, baya kulufumana unyango olukhoyo lokukhulula le miba emizimbeni yabo kwaye baqhubeke nohambo lwabo lwempilo kunye nokuba sempilweni.
Ucaphulo
Appleton, uJeremy. "I-Gut-Brain Axis: impembelelo yeMicrobiota kwiMood kunye nempilo yengqondo." Unyango oludibeneyo (Encinitas, Calif.), InnoVision Health Media Inc., ngo-Agasti 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6469458/.
Bonaz, Bruno, et al. "I-Vagus Nerve Stimulation kwi-Interface ye-Brain-Gut Interface." Cold Spring Harbour Ukujonga kwiNyango, iCold Spring Harbour Laboratory Press, 1 Aug. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6671930/.
Breit, Sigrid, et al. "I-Vagus Nerve njengeModyuli ye-Brain-Gut Axis kwi-Psychiatric and Inflammatory Disorders." Frontiers kwi-Psychiatry, Frontiers Media SA, nge-13 kaMatshi 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5859128/.
Gwak, Min-Gyu, kunye ne-Sun-Young Chang. "UQhagamshelwano lwe-Gut-Brain: I-Microbiome, i-Gut Barrier, kunye ne-Environmental Sensors." Uthungelwano lwe-Immune, Umbutho waseKorea wee-Immunologists, 16 Juni 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8263213/.
UGünther, uClaudia, et al. "I-Gut-Brain Axis kwi-Inflammatory Bowel Disease-Iimbono zangoku kunye nezexesha elizayo." I-International Journal ye-Molecular Sciences, MDPI, 18 Agasti 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8396333/.
Stopińska, Katarzyna, et al. "I-Microbiota-Gut-Brain Axis njengeSitshixo kwi-Neuropsychiatric Disorders: Uphononongo oluncinci." Ijenali yamayeza onyango, MDPI, 10 Okt. 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8539144/.
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