I-Gastro Health Intestinal
Iqela lezonyango eliSebenzayo leKlinikhi yeGastro yamathumbu eSebenzayo. I-gastrointestinal okanye (GI) iphecana lenza okungakumbi kunokwetyisa ukutya. Inegalelo kwiinkqubo ezahlukeneyo zomzimba kunye nemisebenzi. UDkt Jimenez ujonga iinkqubo eziye zenziwa ukunceda ukuxhasa impilo kunye nomsebenzi we-GI iphecana, kunye nokukhuthaza ukulinganisela kwe-microbial. Uphando lubonisa ukuba i-1 kwi-4 abantu base-US banesisu okanye iingxaki zamathumbu ezinzima kangangokuthi ziphazamisa imisebenzi yabo yemihla ngemihla kunye nendlela yokuphila.
Iingxaki zamathumbu okanye ukugaya zibizwa ngokuba yi-Gastrointestinal (okanye i-GI) Disorders. Injongo kukufikelela kwimpilo yokwetyisa. Xa inkqubo yokwetyisa esebenza kakuhle isendleleni, kuthiwa umntu usempilweni entle. Iphecana le-GI likhusela umzimba ngokukhupha i-toxins eyahlukeneyo kunye nokuthatha inxaxheba kwiinkqubo ze-immunological okanye xa amajoni omzimba asebenzisana nama-antibodies kunye nama-antigens. Oku kudityaniswa nokuxhasa ukwetyisa kunye nokufunxa izondlo ezisuka kukutya komntu ngamnye.
by UGqr Alex Jimenez Chiropractic , LweMpilo , I-Gastro Health Intestinal , I-Gut ne-Intestinal Health , Impilo Yesikhumba , I-Viscerosomatic Reflex , Ukuphila
intshayelelo
Njengoko wonke umntu esazi, amathumbu anceda umzimba ukuba udibanise izondlo kunye neevithamini ekufuneka zisebenze ngokuchanekileyo. I Inkqubo yamathumbu kwakhona ivumela umzimba ku khusela ukwenza ngelixa uhlala unxibelelana ne ngengqondo . Amathumbu anceda ukuthumela imiqondiso emva naphambili ukulawula iihomoni zomzimba imiqondiso kunye nezinye izinto eziluncedo ezifunwa ngumzimba. Amathumbu nawo anxibelelana nelona lungu likhulu emzimbeni, elulusu. Xa izinto ezinganyamezelekiyo ziqala ukonakalisa amathumbu kwaye zibangele isiphithiphithi ngaphakathi kwinkqubo yamathumbu, iphazamisa imiqondiso yobuchopho kwinkqubo ye-nervous kwaye inokuthatha umonakalo eluswini. Inqaku lanamhlanje liza kugxila kwimeko yolusu eyaziwa ngokuba yi-rosacea, ukuba iyichaphazela njani inkqubo yamathumbu, kwaye yintoni unxibelelwano lwesikhumba. Ukubhekisa izigulana kubaboneleli abaqinisekisiweyo, abanezakhono abaziingcali kunyango lwe-gastroenterology. Sinikezela ngesikhokelo kwizigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo ibalulekile ekubuzeni imibuzo eqondayo kubaboneleli bethu. UDkt Alex Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli
Ngaba i-inshorensi yam ingayihlawula? Ewe, kunokwenzeka. Ukuba akuqinisekanga, nali ikhonkco kubo bonke ababoneleli beinshorensi esibakhuselayo. Ukuba unemibuzo okanye iinkxalabo, nceda ufowunele uDkt Jimenez kwi-915-850-0900.
Yintoni iRosacea?
Ngaba ukhe waziva nakuphi na ukuphazamiseka kwamathumbu okufana ne-IBS, amathumbu avuzayo, okanye iGERD echaphazela icandelo lakho eliphakathi? Kuthekani ngobubomvu obujikeleze ubuso bakho, ngakumbi iimpumlo nezidlele? Ngaba ulusu lwakho lubonakala luthambile kwindawo ethile? Uninzi lwezi mpawu zinxulumene nesifo esingapheliyo sokudumba esaziwa ngokuba yi-rosacea. Ngokuqhelekileyo kuboniswa ngamacandelo ofuzo kunye nokusingqongileyo okunokubangela ukuqaliswa kwe-rosacea eluswini. I-Rosacea ngokuqhelekileyo yenziwa mandundu kukunganyangeki kakuhle kwenkqubo yomzimba yokulwa izifo ezizalwa nayo. Uphando lophando lukhankanyile ukuba i-rosacea idla ngokuphuhliswa yi-lymphatic dilation kunye nemithambo yegazi evezwe kumaqondo obushushu agqithisileyo, iziqholo, okanye utywala obubangela ukuba i-rosacea ichaphazele izidlele kunye neempumlo. Akunjalo kuphela, kodwa i-genetics, i-immune reaction, i-microorganisms, kunye nezinto ezisingqongileyo zikhokelela kubalamli abahlukeneyo njenge-keratinocytes, iiseli ze-endothelial, iiseli ze-mast, i-macrophages, uhlobo lomncedisi we-T 1 (TH1), kunye neeseli ze-TH17.
Ichaphazela Njani Inkqubo Yamathumbu?
Ekubeni i-rosacea iphuhliswa ngokuvezwa kwamaqondo aphezulu, iziqholo, okanye utywala, izifundo zophando zibonisile oko kutya kunye neziselo ezithile kubangela ukuba i-cytokines evuthayo iqalise ebusweni. Ukongezelela, izinto ezininzi ezibangela ukuba zikwazi ukunxibelelana ngokuthe ngqo kwinkqubo ye-nervous cutaneous; I-neurovascular and neuro-immune neuropeptides esebenzayo ikhokelela ekubonakalisweni kwezilonda ze-rosacea. Ezinye zezinto ezibangela ukuba i-rosacea ikhule yinkqubo yamathumbu engenampilo. A uphononongo lubonisiwe ukuba ngaphezu kwe-50% ine-asidi yesisu ephantsi phakathi kwezigulane ezine-rosacea kunye ne-dyspepsia. Ibhaktheriya i-H.pylori ihlala esiswini kwaye iye yaqatshelwa ukuba iqalise ukuvutha kunye nokugungxula okubangelwa yi-gastrin, oko kubangela i-rosacea. Izifundo ezongezelelweyo zikhankanyiwe ukuba abantu be-rosacea baya kufumana ukuphazamiseka kwamathumbu ukuba kwenzeke. Kuba inkqubo yamathumbu inokunikezela kwizinto ezahlukeneyo, inokuchaphazela ukubunjwa kwamathumbu kwaye ibangele i-rosacea. Kuba i-gut microbiota inefuthe kwi-homeostasis yomzimba, inokuchaphazela ulusu. Xa kukho izinto ezibangela umqobo wamathumbu emathunjini, unokuchaphazela ulusu, okubangela ukuba i-cytokines evuthayo iqhubeke nokuphuhliswa kwe-rosacea.
Ukutyhila uQhagamshelwano lweGut-Skin-Video
VIDEO
Ngaba ulusu lwakho luziva lugungxulwe ngenxa yobushushu obugqithisileyo okanye ukutya okuneziqholo? Ngaba ukhe wafumana ukuphazamiseka kwamathumbu okufana ne-SIBO, i-GERD, okanye amathumbu avuzayo? Ngaba ulusu lwakho lubonakala lugqabhuka ngakumbi kunokuba lufanele? Ulusu lwakho lunokuchatshazelwa yi-gut microbiota yakho, njengoko le vidiyo ingasentla ibonisa ukuba yintoni unxibelelwano lwesikhumba samathumbu kunye nendlela abasebenza ngayo omnye komnye. Izifundo zophando zibonisile kuba i-microbiome yamathumbu ingumlawuli ophambili wokhuselo lomzimba, idlala indima ebalulekileyo kwiziphazamiso ezahlukeneyo zolusu. Oku kuthetha ukuba xa izinto zokusingqongileyo zichaphazela i-microbiome yamathumbu, ichaphazela ulusu nge-dysbiosis.
Yintoni uQhagamshelwano lweGut-Skin?
Njengoko bekutshiwo ngaphambili, inkqubo yamathumbu ilikhaya leetriliyoni zemicroorganisms ezinceda ukuhlaziya i-homeostasis yomzimba, kubandakanya nelona lungu likhulu, ulusu. Izifundo zophando zifumene ukuba xa amathumbu microbial kunye nolusu ukunxibelelana omnye komnye. Yenza uxhulumaniso lweendlela ezimbini. I-gut microbiome ikwangumlamli obalulekileyo wokudumba emathunjini kwaye ichaphazela ulusu. Xa kukho izinto ezinje ngokumelana ne-insulin, ukungalingani kwiihomoni zesini, ukudumba kwamathumbu, kunye ne-microbial dysbiosis eyonakalisayo inkqubo yamathumbu, iziphumo zinokubangela i-pathology yokuphazamiseka kokudumba okuchaphazela ulusu. Naluphi na utshintsho emathunjini lunokuchaphazela ulusu njengoko amathumbu etya ukutya ukuze kuguqulwe i-biotransform ibe izondlo ezifunwa ngumzimba. Kodwa xa ukutya kunye nobuthathaka kuchaphazela amathumbu, ulusu nalo luyabandakanyeka, lubangela ukuphazamiseka kolusu njengerosacea.
isiphelo
Ngokubanzi amathumbu aqinisekisa ukuba umzimba usebenza ngokuchanekileyo ngokugalela izondlo kukutya okusetyenzisiweyo. Inkqubo yamathumbu inonxibelelwano kungekuphela nje kwingqondo kunye ne-immune system kodwa kunye nolusu. Uqhagamshelo lolusu luhamba kunye njengoko izinto ezichaphazela amathumbu zinokuchaphazela ulusu ekuphuhliseni ukuphazamiseka kwesikhumba njengerosacea. Xa umntu enengxaki yokuphazamiseka kwamathumbu, ulusu lwakhe lonakaliswa zizinto ezifana noxinzelelo, ubuthathaka bokutya, kunye nokuphazamiseka kolusu olunokuba yinkathazo. Oku kunokuncitshiswa ngotshintsho oluncinci olunjengokunciphisa uxinzelelo, ukutya ukutya okunempilo, kunye nokwenza umthambo, okuluncedo ekuthomalaliseni amathumbu kunye nokuphazamiseka kolusu kubantu abafuna ukubuyisela impilo yabo.
Ucaphulo
Daou, Hala, et al. "IRosacea kunye neMicrobiome: Uphononongo olucwangcisiweyo." I-Dermatology kunye noNyango , Springer Healthcare, Feb. 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC7859152/ .
De Pessemier, Britta, et al. "I-Gut-Skin Axis: Ulwazi lwangoku lokuNxibelelana phakathi kweMicrobial Dysbiosis kunye neeMeko zolusu." Iintsholongwane , MDPI, 11 Feb. 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC7916842/ .
Farshchian, uMehdi, kunye noSteven Daveluy. "Rosacea." Ku: StatPearls [Internet]. Isiqithi saseTreasure (FL) , StatPearls Publishing, 30 Dec. 2021, www.ncbi.nlm.nih.gov/books/NBK557574/ .
Kim, Hei Sung. "I-Microbiota eRosacea." Ijenali yaseMelika yeClinical Dermatology , iSpringer International Publishing, ngoSeptemba 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7584533/ .
Mikkelsen, Carsten Sauer, et al. "IRosacea: Uphononongo lweKlinikhi." Iingxelo zeDermatology , IPHEPHAPress Publications, Pavia, Italy, 23 Juni 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC5134688/ .
Salem, Iman, et al. "I-Gut Microbiome njengoMlawuli oMkhulu we-Gut-Skin Axis." Imida kwi Microbiology , Frontiers Media SA, 10 Julayi 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6048199/ .
isikhanyeli
by UGqr Alex Jimenez Chiropractic , I-Gastro Health Intestinal , I-Gut ne-Intestinal Health , I-Viscerosomatic Reflex , Ukuphila
intshayelelo
The Inkqubo yamathumbu likhaya leetriliyoni zeebhaktheriya eziluncedo ezinceda ukutya okuguqulwe ngebhayoloji kube izondlo ukuze umzimba usebenze ngokuchanekileyo. Amathumbu nawo ahlala enxibelelana nengqondo njengoko imiqondiso ye-neuron ikwi- ubude bemaza obu-bi-directional oko kunceda ukuhambisa izondlo kwiindawo zabo ezichongiweyo emzimbeni. Ezi ndawo zichongiweyo zinceda umzimba ngokunjalo, njengoko zineseti yazo yemiyalelo yokusebenza ngokuchanekileyo ngelixa umzimba usashukuma. Xa ukuphazamiseka kwamathumbu okufana ne-metainflammation kuqala ukuphazamisa imiqondiso ebuyela umva naphambili phakathi kwengqondo kunye namathumbu, kunokubangela imiba eyahlukeneyo enokubangela ukuba umzimba ungasebenzi kakuhle kwaye uqhubele phambili ekudumbeni okungapheliyo. Inqaku lanamhlanje lixoxa ngento eyenziwa yi-metainflammation kwi-axis ye-gut-brain kunye nendlela ii-inflammasomes ezidlala ngayo indima yazo kwi-axis yesibindi emzimbeni. Ukubhekisa izigulana kubaboneleli abaqeqeshiweyo, abanezakhono abaziingcali kunyango lwe-gastroenterology. Sinikezela ngesikhokelo kwizigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo ibalulekile ekubuzeni imibuzo eqondayo kubaboneleli bethu. UDkt Alex Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli
Ngaba i-inshorensi yam ingayihlawula? Ewe, kunokwenzeka. Ukuba akuqinisekanga, nali ikhonkco kubo bonke ababoneleli beinshorensi esibakhuselayo. Ukuba unemibuzo okanye iinkxalabo, nceda ufowunele uDkt Jimenez kwi-915-850-0900.
I-Metainflammation echaphazela i-Gut-Brain Axis
Ngaba ukhe waphawula ukwanda kokungadibani nokutya okanye ukunganyamezeli okukuchaphazelayo? Kuthekani ngokuziva iingxaki zokwetyisa zinyuka ngamaxesha amaninzi? Uninzi lwezi mpawu zibangelwa kukuphazamiseka kwamathumbu okufana ne-metainflammation, enokuthi ichaphazele i-axis yobuchopho emzimbeni. Uphando lophando lukhankanyile ukuba inkqubo ye-nervous ichaphazela ngokuthe ngqo amathumbu ngokusebenzisa abalamli be-endocrine abasebenzisana ne-microbial receptors. Xa i-metainflammation iqala ukuchaphazela amathumbu, iba sisiphumo se-dysbiosis yamathumbu ehlukeneyo njenge:
Ukunyuka kokulala kunye nokuphazamiseka kwemizwelo Ukukhathala Ukunciphisa ukusebenza kunye nekhono lokuzilolonga Ukunqongophala kwezondlo - i-vitamin D, iivithamini B Ukungalingani kwedlala lengqula
Ezinye izifundo zophando zibonisile ukuba ekubeni ukudumba kuyinto eqhelekileyo kwiziphazamiso ezahlukeneyo ezichaphazela umzimba, kunokwenza umonakalo omkhulu xa ii-cytokines ezivuthayo zichaphazela i-axis ye-gut-brain kunye ne-immune system. Ukudumba kwe-Meta kubangela ukuncipha kokufunxa kwamathumbu kunye nokucutheka, kodwa kunokonyusa iindawo ezixineneyo ezineziphene kunye nokungena kwamathumbu. Oku kubangela ukuba imiba yamathumbu ikhule njenge-Crohn's kunye nesifo se-celiac, ebangela ukunyuka kwe-insulin kunye nokukhubazeka komzimba kunye nemiba yengqondo efana nokulala, ukuqonda, ukuphazamiseka kwemizwelo, ukuxhalaba kunye nokuphazamiseka kwengqondo.
Isishwankathelo kwividiyo ye-Gut-Brain-Axis-Video
VIDEO
Ngaba ufumene ubunzima malunga necandelo lakho eliphakathi? Kuthekani ngokunyuka kwenkumbulo kunye nokuncipha kwengqondo? Ngaba ukhe waziva ukunyuka kokudumba okungapheliyo okanye iingxaki zokhuselo lomzimba? Zonke ezi zimpawu ziimpawu zokuba unokuba ne-metainflammation echaphazela i-axis yobuchopho emzimbeni wakho. Le vidiyo ingasentla icacisa i-axis ye-gut-brain kunye nokuba ukuphazamiseka kwe-neurodevelopment kunokuchaphazela njani ingqondo. Izifundo zophando zifumene ukuba umxube we-dysbiosis kunye nokuvuvukala kuchaphazela amathumbu, kwaye kunokubangela ukuba ingqondo idibaniswe nezifo ezininzi ze-neurological. Ngonxibelelwano lwe-bi-directional ingqondo kunye namathumbu analo, izinto ezininzi zihlala zicela umngeni kuzo zombini ii-microbiomes ezinokuqhubela phambili iimpawu zokuvuvukala ukuba zinyuke emzimbeni.
Yintoni I-Inflammasomes?
I-Inflammasomes yintsapho yeeprotheni ezijongene nokuqalisa inkqubo yokuvuvukala ngexesha lokuphendula kwe-immune. I-Inflammasomes ziziintsholongwane ezikhuselayo ezibangela iziphumo zokudumba ngokuchasene nosulelo kwaye zinokuchaphazela i-axis yesibindi emzimbeni ukuba ijika ingapheli. Yintoni eyenziwa yi-inflammasomes kukuba inceda i-receptors yokuqaphela ipateni ukwazi xa umzimba uziva ucinezelekile okanye usengozini, njengoko bengabadlali ababalulekileyo kwi-metaflammation construct. Izifundo zophando zibonisile ukuba i-inflammasomes emzimbeni inokunceda ukukhupha i-toxins kwii-microbes ezihlaselayo ezibangela ukuphazamiseka kwamathumbu.
I-Inflammasome iyichaphazela njani i-Gut-Liver Axis?
I-axis yesibindi se-gut idityaniswe namathumbu nge-bile acid metabolism. I-Bile acid dysregulation ingakhokelela kwi-intestinal dysbiosis, evumela ukuba i-gram-negative erogenous pathogenic bacteria kunye ne-LPS ukuba ingene esibindini. Xa oku kwenzeka, kubangela ukuvuvukala kwesibindi nge-inflammasomes. Izifundo zophando zibonisile ukuba ukuvuvukala okungapheliyo okuchaphazela i-axis yesibindi se-gut kunokubangela ukuba i-inflammasomes ichaphazele ingqibelelo yodonga lwe-epithelial kwaye ibangele nokuveliswa kwe-cytokine ye-pro-inflammatory, ebangela imiba emininzi emzimbeni. Ngokwahlukileyo, i-NLRP3 inflammasome ngokuyintloko yenza i-IL-1beta ngokubangela i-bile acids ukuba isebenze i-NLRP3 inflammasome kwi-macrophages. Oku kubangela ukudluliselwa kwebhaktheriya ukuvumela iintsholongwane, okt, i-Bacteroidetes (ibhaktheriya ye-Gram-negative) kunye ne-LPS, kwisibindi.
isiphelo
Ngokubanzi, i-axis ye-gut-brain ivumela unxibelelwano lwe-bi-directional kuwo wonke umzimba njengoko uncedo lwamathumbu lulawula umsebenzi we-metabolic womzimba. Kwangaxeshanye, ingqondo ilawula imiqondiso kunye neenkqubo ezidibana nomzimba. Xa imiba engapheliyo efana ne-metainflammation okanye i-inflammasomes engapheliyo iqala ukuchaphazela amathumbu, inokuphazamisa unxibelelwano lwe-bidirectional kwingqondo, ebangela ukuba umzimba ungasebenzi. Ukubandakanya utshintsho oluncinci kukhetho lobomi oluqinisekileyo njengokongeza izongezo kunye nezakhamzimba ukuthomalalisa ukudumba, ukutya okunempilo, kunye nokwenza umthambo kunokunceda ukukhulula amathumbu. Xa abantu abaninzi besenza olu tshintsho luncinci kuhambo lwabo lwezempilo kunye nokuba sempilweni, banokuziva benamandla angakumbi, bazive ukudumba okuncinci okuchaphazela amathumbu abo, kwaye bajikeleze ngakumbi.
Ucaphulo
UClapp, uMegan, kunye nabanye. "Impembelelo yeGut Microbiota kwiMpilo yengqondo: I-Gut-Brain Axis." Iiklinikhi kunye nokuziqhelanisa , IPHEPHAPress Scientific Publications, Pavia, Italy, 15 Sept. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5641835/ .
de Zoete, Marcel R, et al. "Izinto ezivuthayo." Iingqungquthela zeCold Spring Harbour kwi-Biology , iCold Spring Harbour Laboratory Press, 16 Okt. 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4292152/ .
Herradon, Gonzalo, et al. "Ukudibanisa i-Metainflammation kunye ne-Neuroinflammation ngokusebenzisa i-PTN-Mk-Rptpβ / ζ i-Axis: Ukufaneleka kuPhuhliso lwezoNyango." Imida kwi-Pharmacology , Frontiers Media SA, 12 Epreli 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6474308/ .
Osadchiy, Vadim, et al. "I-Gut-Brain Axis kunye neMicrobiome: Iinkqubo kunye neeMpembelelo zoNyango." I-Clinical Gastroenterology kunye ne-Hepatology: iJenali yokuSebenza yeKlinikhi esemthethweni ye-American Gastroenterological Association , ILayibrari yeSizwe yezeMithi yase-US, uJanuwari 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6999848/ .
Wang, Junfeng, et al. "Iindima ze-Inflammasome kwi-Gut-Liver Axis (Uphononongo)." Iingxelo zeMolekyuli yamayeza , DA Spandidos, ngoJan. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6297761/ .
isikhanyeli
by UGqr Alex Jimenez Chiropractic , LweMpilo , I-Gastro Health Intestinal , I-Gut ne-Intestinal Health , nezongezo , I-Viscerosomatic Reflex
intshayelelo
The Inkqubo yamathumbu sisixokelelwano esikhulu sendalo esinceda ekulungiseni umzimba inkqubo yomzimba kwaye utshintsho lwemetabolism ukuba umzimba ngokwawo udlulayo. Inkqubo yamathumbu ibonelela umzimba ngezondlo eziyimfuneko ukuze usebenze ngokuchanekileyo kwaye uhambisa ezi zondlo ukuya kumacandelo awo ahlukeneyo njenge inkqubo ye endocrine , i luvo , kwaye i inkqubo yemisipha ukwenza imisebenzi yabo. Xa ukuphazamiseka kwamathumbu kuqala ukuchaphazela iindonga zamathumbu, kunokubangela ukuba ii-cytokines ezivuthayo zihlasele iindonga zamathumbu ngenxa yeebhaktheriya kunye nezondlo eziphuma kwiindawo eziqinileyo. Ngethamsanqa, kukho iindlela zonyango zokunceda inkqubo yamathumbu kunye nokuthintela ukuvuvukala kubangele imiba emininzi emathunjini. Inqaku lanamhlanje lijonga kwi-gut metainflammation kunye nendlela i-nutraceuticals enokubanceda ngayo abantu abaninzi abane-gut metainflammation. Ukubhekisa izigulana kubaboneleli abaqeqeshiweyo, abanezakhono abaziingcali kunyango lwe-gastroenterology. Sinikezela ngesikhokelo kwizigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo ibalulekile ekubuzeni imibuzo eqondayo kubaboneleli bethu. UDkt Alex Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli
Ngaba i-inshorensi yam ingayihlawula? Ewe, kunokwenzeka. Ukuba akuqinisekanga, nali ikhonkco kubo bonke ababoneleli beinshorensi esibakhuselayo. Ukuba unemibuzo okanye iinkxalabo, nceda ufowunele uDkt Jimenez kwi-915-850-0900.
Yintoni iGut Metainflammation?
Ngaba inkqubo yakho yamathumbu ivakala ibuhlungu okanye ithenda xa uyibamba? Ngaba izinto eziqhelekileyo ezifana noxinzelelo, iingxaki zokulala, ukungalingani kwehomoni, kunye nemiba ye-cardiovascular kuchaphazela ngaphezu kokuba kufuneka babe nayo? Ngaba ukhe wahlangabezana nemiba yokukrala kwamathumbu njenge-IBS okanye amathumbu avuzayo? Ukuba naluphi na ukuphazamiseka kwamathumbu akukho nto ihlekisayo kwimpilo yakho. Xa inkqubo yamathumbu ifumana i-sequela engapheliyo yokuvuvukala okukwibakala elisezantsi, yile nto i-gut metainflammation ikuyo emzimbeni. I-Gut metainflammation ichazwa njengokusebenza ngokugqithisileyo kokugonyeka emathunjini okukhokelela ekwandeni kwemveliso ye-cytokines evuthayo, ngaloo ndlela ibhekisa kwi-metabolism-induced inflammation. Izifundo zophando zibonisile ukuba xa amathumbu efumana i-metainflammation, ibangela ukuphazamiseka kwiindlela ze-neurometabolic. Oku kubangela ukwanda kweenkqubo zokuguga kunye nemiba yokubonakaliswa kwe-metabolic amathumbu azama ukubonelela umzimba. Ezinye izifundo zophando zibonisile ukuba i-metainflammation yenye yeempawu eziphambili zokuphazamiseka kwemetabolism njengokutyeba, uhlobo lwe-2 yeswekile, kunye ne-NAFLD (isifo sesibindi esinamafutha e-nonalcoholic). I-Gut metainflammation ikwabangela ukonyuka kwe-peripheral kunye nokudumba okuphakathi okunokubangela ukuphazamiseka kwamathumbu njengokuvuza kwamathumbu ukuvumela iibhaktheriya kunye ne-toxins ukuba zingene egazini, nto leyo ekhokelela ekudumbeni kwe-peripheral kunye nombindi womzimba.
Unyango lwe-GI Disorders-Ividiyo
VIDEO
Ngaba ukhe wadibana namathumbu avuzayo? Ngaba uziva udiniwe imini yonke? Ngaba ukhe wanamava obuthathaka okutya emathunjini akho? Le miba yamathumbu ibangelwa kukudumba kwe-metainflam enokuthi ibe nefuthe kwimpilo yomntu kunye nomgangatho wobomi. Xa oku kusenzeka, umzimba uya kuba ungasebenzi, kwaye eminye imiba iya kuvela ngaphandle kokuba inyangwe kwangoko. Le vidiyo ingasentla ibonisa ukuba lufumaneka njani unyango lokunciphisa ukuphazamiseka kokuhamba kunye nokuphazamiseka kwe-GI okuchaphazela inkqubo yamathumbu. Ukusebenzisa unyango oluluncedo kwinkqubo yamathumbu kunokunceda ukuthomalalisa iziphumo ze-metainflammation kunye nolunye ukuphazamiseka kwamathumbu ekuqhubeleni phambili emzimbeni. Olunye unyango olunokunceda ngokukhupha i-metainflammation kwi-gut system inokufumaneka ngokuguqula indlela yokutya kunye nokubandakanya i-nutraceuticals enenzuzo emathunjini.
Ukulawula i-Gut Metainflammation ngokusebenzisa i-Nutraceuticals
Izifundo zophando zibonisile ekubeni iitriliyoni zeeseli ze-microbial zenza i-gut microbiota xa izinto ezifana nokutyeba, i-metainflammation, kunye nokuphazamiseka komsebenzi we-insulin kuchaphazela amathumbu, kunokubangela ukuba iiseli zokuzivikela ziphinde zisebenze kwaye zomeleze inkqubo yokuvuvukala ukuhlasela inkqubo yamathumbu. Xa inkqubo yamathumbu ingasebenzi, abantu abaninzi bazama ukufumana iindlela zokuphelisa ukudumba kwamathumbu. Olunye lonyango kukubandakanya i-nutraceuticals ukunika isiqabu kwi-gut metainflammation. Uphando lophando lukhankanyile ezidityaniswe nokutya okusebenzayo kunokunceda ukunika impembelelo entle kwimetabolism yomzimba kunye ne-gut microbiota. I-Nutraceuticals inceda ukunika umzimba izondlo eziyimfuneko kwaye incede ekudambiseni naziphi na iziphumo zokuphazamiseka okuchaphazela amathumbu omzimba, amajoni omzimba, kunye namalungu e-metabolic. I-nutraceuticals ezimbini zinokunceda ukulawula i-metainflammation yamathumbu: i-curcumin kunye ne-peptides.
I-Curcumin kunye neePeptides zeGut Metainflammaion
Ukusuka kwi-turmeric (i-Curcuma longa) ingcambu / irhizome kwaye isetyenziswa ngokwesiko kwiimeko ze-dyspeptic, uphando lophando lukhankanyile ukuba i-curcumin kunye ne-anti-inflammatory metabolites inokunceda ukuchaphazela i-gut microbiota. Yintoni eyenziwa yi-curcumin emathunjini kukuba inceda ukunciphisa ukubonakaliswa kwe-inflammasome ngelixa inciphisa uxinzelelo lwe-oxidative nge-Nrf2-keap1 indlela. I-Curcumin inokunceda ukuphucula ukuguquguquka kunye nokuhamba emzimbeni ngelixa inqanda ukusebenza kwe-peroxisome proliferator-activated receptor-gamma indlela. Ulwazi olongezelelweyo lunikiwe ukuba i-curcumin ayinakunceda kuphela ukunciphisa uxinzelelo lwe-oxidative kunye nokukhusela i-neurodegeneration.
Iipeptides okanye i-BPC-157 (iCompound yoKhuseleko loMzimba) ziphuma kwijusi yesisu somntu ene-cytoprotective kunye ne-anti-inflammatory enceda ukuxhasa i-gut mucosal lining. Izifundo zophando zibonisile ukuba i-peptides idlala indima ebalulekileyo ekugcineni i-homeostasis yamathumbu ngelixa isebenza kakuhle ekunciphiseni ukubonakaliswa kwe-metainflammatory kwi-gut microbiota. Xa kukho i-metainflammation emathunjini, iipeptides zinokunceda ukuphucula ukusinda kweeseli phantsi kweemeko zoxinzelelo lwe-oxidative ngokuthoba i-TNF-alpha emzimbeni. Ukubandakanya iipeptide kunokunceda ukuphucula ingqibelelo ye-mucosal ye-GI ukusuka kwi-meta yokuvuvukala kunye nokunceda amathumbu asebenze ngokuqhelekileyo.
isiphelo
Amathumbu likhaya leetriliyoni zeemicroorganisms ezinceda ukugcina ukusebenza komzimba kunye nokulawula ukhuseleko kwizifo ezahlukeneyo. Xa izinto ezingafunekiyo ezifana ne-metainflammation iqala ukungena emathunjini, inokukhokelela kwi-dysbiosis kwaye ichithe iindonga zamathumbu. I-Nutraceuticals efana ne-curcumin kunye ne-peptides ineepropathi eziluncedo ezinceda ukulungisa iindonga zamathumbu ngelixa zithomalalisa iziphumo ezivuthayo ezivela ekuqhubeleni phambili kwinkqubo yamathumbu. Ukubandakanya i-nutraceuticals luncedo kubantu abaninzi abanengxaki yokuphazamiseka kwamathumbu kunye nokuphucula impilo yabo ngokuzalisa izondlo zabo emzimbeni.
Ucaphulo
Boulangé, Claire L, et al. "Impembelelo yeGut Microbiota ekuKhumbeni, ukutyeba, kunye neSifo seMetabolic." Amayeza eGenome , BioMed Central, 20 Epreli 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4839080/ .
UDi Meo, uFrancesco, kunye nabanye. "I-Curcumin, i-Gut Microbiota, kunye ne-Neuroprotection." Amanzi , MDPI, 11 Okt. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6835970/ .
Gubatan, John, et al. "I-Peptides ye-Antimicrobial kunye ne-Gut Microbiome kwiSifo sokuKhuleka kwamathumbu." Ijenali yehlabathi ye-Gastroenterology , Baishideng Publishing Group Inc, 21 Nov. 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8613745/ .
Laparra, JM, kunye noY Sanz. "Intsebenziswano ye-Gut Microbiota kunye nezixhobo eziSebenzayo zokutya kunye neNutraceuticals." Uphando lwezeMpilo , Ilayibrari yeSizwe yaseMelika yoNyango, nge-13 kaNovemba 2009, yentshutshiso.ncbi.nlm.nih.gov/19914380/ .
Scazzocchio, Beatrice, et al. "Intsebenziswano phakathi kwe-Gut Microbiota kunye ne-Curcumin: Isitshixo esitsha sokuqonda kwiimpembelelo zeMpilo ye-Curcumin." Amanzi , MDPI, 19 Agasti 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7551052/ .
Scheithauer, Torsten PM, et al. "I-Gut Microbiota njengeNtshukumo yokuKhuleka kweMetabolic kuKutyeba kakhulu kunye noHlobo lwesi-2 seswekile." Imida e-Immunology , Frontiers Media SA, 16 Okt. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7596417/ .
Tilg, Herbert, et al. "I-Intestinal Microbiota iFakela ukudumba kweMetabolic." UPhononongo lweNdalo. Ugonyo , Ilayibrari yeSizwe yezeMithi yase-US, nge-6 ka-Agasti 2019, yentshutshiso.ncbi.nlm.nih.gov/31388093/ .
isikhanyeli
by UGqr Alex Jimenez Chiropractic , LweMpilo , I-Gastro Health Intestinal , I-Gut ne-Intestinal Health , I-Viscerosomatic Reflex , Ukuphila
intshayelelo
Xa kuziwa kwi Inkqubo yamathumbu , eyona nto iphambili kuyo kukuqinisekisa ukuba umzimba unikwa izondlo kwaye wetyise ukutya okusetyenzisiweyo okutyiwa ngumntu. Izondlo eziluncedo zinceda umzimba ukuba uhlale ushukuma, ngelixa inkqubo yamathumbu inxibelelana rhoqo omzimba kwaye i kwinkqubo yomnatha . I-gut microbiota ikwagcina iibhaktheriya eziluncedo ezinceda ukugcina amathumbu esebenza kwaye ajike ukutya okutyiwayo kube zizondlo kunye neevithamini ukuze zisasazwe kuwo wonke umzimba. Xa izinto eziphazamisayo ziqala ukuchaphazela i-gut microbiota, inokubangela iimpawu ezingafunekiyo, ezibangela ukuba umzimba ungasebenzi. Inqaku lanamhlanje liza kuxoxa ngendlela i-gut microbiota inceda ngayo umzimba kunye nendlela izondlo ezinempilo ezifana ne-probiotics kunye nokutya okuvundisiweyo kunceda ukuxhasa inkqubo yamathumbu. Ukubhekisa izigulana kubaboneleli abaqeqeshiweyo, abanezakhono abaziingcali kunyango lwe-gastroenterology. Sinikezela ngesikhokelo kwizigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo ibalulekile ekubuzeni imibuzo eqondayo kubaboneleli bethu. UDkt Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli
Ngaba i-inshorensi yam ingayihlawula? Ewe, kunokwenzeka. Ukuba akuqinisekanga, nali ikhonkco kubo bonke ababoneleli beinshorensi esibakhuselayo. Ukuba unemibuzo okanye iinkxalabo, nceda ufowunele uDkt Jimenez kwi-915-850-0900.
IGut Microbiota iwunceda njani umzimba?
Ngaba ukhe waziva ungakhululekanga emathunjini akho? Kwi-gut microbiota yakho, ngaba ufumana ukungonwabi ukudumba okunje IBS , SIBO , okanye I-GERD ? Ngaba uziva uphantsi okanye uziva utyhafile imini yonke? Uninzi lwezi mpawu athe umntu wadibana nazo zinxulunyaniswa nenkqubo yamathumbu kwaye inokuqhubeka ixesha elide xa inganyangwa kwangoko. Izifundo zophando ziye zachaza I-gut microbiota njengenkqubo yelungu elintsonkothileyo elinabantu abaguqukayo beentsholongwane eziphembelela umzimba ngexesha le-homeostasis kunye nezifo ezidibana nazo. Umzimba udinga inkqubo yamathumbu kuba idlala indima ebalulekileyo ekugcineni ukhuselo lomzimba kunye ne-metabolic stasis ngelixa ukhusela usulelo. Izifundo ezongezelelweyo zibonisiwe ukuba xa umzimba usenza utshintsho olwahlukileyo njengeendlela zokutya, utshintsho lwendlela yokuphila, okanye imisebenzi yomzimba inokuchaphazela i-gut microbiota. Naluphi na olu tshintsho lunokuchaphazela inkqubo yamathumbu ngokuguqula ukubunjwa kunye nokuxinana kwamathumbu. Xa utshintsho luyingozi emathunjini, lunokubangela iimpawu ezingafunekiyo ezibangela ukungasebenzi kakuhle emathunjini; nangona kunjalo, xa utshintsho lulungile, lunokunceda inkqubo yamathumbu ngeendlela ezininzi ezinceda umzimba.
Iingcebiso zokugcina iMicrobiota esempilweni-Ividiyo
VIDEO
Ngaba uziva udiniwe imini yonke? Ngaba uye wanovelwano kukutya okutyayo? Ngaba ukhe wahlangabezana neenkqubo zokudumba kwamathumbu ezifana neGERD, IBS, okanye SIBO ezichaphazela ubomi bakho? Abantu abaninzi abaneengxaki zamathumbu bazama ukufumana iindlela zokuyithoba kunye nokutshintsha indlela abatya ngayo. Ngamanye amaxesha ukubandakanya ukutya okunempilo emathunjini kunye nezongezo ziluncedo ekukhuleni kwakhona kweflora emathunjini ngelixa kuthomalalisa iziphumo zokudumba ezibangelwa yimiba enxulumene namathumbu. Isondlo esinempilo kunye ne-nutraceuticals enceda i-gut microbiota inokulungisa udonga lwamathumbu emathunjini kwizinto ezivuthayo ezihlasela amathumbu. Le vidiyo ingasentla inika inkcazo-ntetho egqwesileyo kwiingcebiso ezintlanu zokugcina i-microbiota yamathumbu esempilweni. Xa abantu abaninzi beqala ukutshintsha indlela abatya ngayo ukuze baphucule inkqubo yabo yamathumbu, baya kufumana amandla angakumbi kunye nethumbu elonwabileyo.
Izondlo ezisempilweni zeNtumbu
Xa kuziwa kwinkqubo yamathumbu kunye nokuzama ukuyigcina iphilile, eyona ndlela ingcono umntu anokuyenza ngayo ngokufumanisa ukuba kukuphi ukutya okunempilo okunenzuzo emathunjini kwaye kunika amandla emzimbeni. Kuba abantu abaninzi bafuna ukutshintsha indlela abatya ngayo ukusuka ekutyeni ukutya okucoliweyo ukuya kukutya okunesondlo ngokupheleleyo, uphando lophando lufumene ukuba ekubeni i-gut microbiota iyinkqubo eguqukayo yendalo, izicwangciso zokutya umntu ahamba phantsi kwazo zinokunceda ukukhusela izifo kunye nokugcina amathumbu anempilo. Enye yeendlela ezilungileyo umntu anokuthi azenze ukuze aqinisekise ukuba amathumbu asempilweni kukutya ukutya okutyebileyo kwe-prebiotic, ukutya okubilisiweyo, kunye nokutya okukhulisiweyo ukulinganisa iintsholongwane zamathumbu. Ezi zondlo zimbini zinceda ukuzinzisa amathumbu xa iibhaktheriya ezinobungozi ziqala ukugcwala ngaphakathi kwamathumbu kwaye zinciphise iibhaktheriya eziluncedo kwinkqubo yamathumbu.
Iiprobiotics kunye noKutya okuGqilisiweyo
Iiprobiotics zichazwa njenge-substrate ekhethwa ngokukhethekileyo yi-microorganisms ekhoyo enika inzuzo yezempilo kwinkqubo yamathumbu. Izifundo zophando ziye zachaza iiprobiotics ziphila iibhaktheriya eziluncedo ezinceda ukuthoba iziphumo ezivuthayo kwiindonga zamathumbu kunye nokunceda ukuzalisa i-flora yamathumbu kwinkqubo yamathumbu. Uphando olongezelelweyo nalo lubonisile ukuba i-pro kunye ne-prebiotics inceda ukuvuselela ukukhula okuncedo kwee-microorganisms emathunjini. Iiprobiotics zinokunciphisa iingxaki ezininzi ezichaphazela amajoni omzimba, intliziyo, kunye nemiba yamathumbu umntu ajongana nayo.
Kanye njengeprobiotics, ukutya okubilisiweyo kunokukhuthaza i-microbiome enempilo yamathumbu. Ukutya okuvundisiweyo kugaywa ngakumbi ngelixa kuvelisa i-peptides ye-bioactive efana ne-CLA kunye ne-bacteriocins emathunjini. Ukutya okuvundisiweyo kukwavumela iipolyphenols zibe kwimeko esebenzayo ebandakanya iivithamini, umsebenzi we-enzyme, kunye nemveliso ye-amino acid ngelixa uphucula ukufunxa kwamaminerali. Izifundo zophando zibonisile ukuba ukutya okubilisiweyo kunceda ukulungelelanisa i-microbial yamathumbu kunye nokusebenza kwengqondo. Ukutya okuvundisiweyo kukwaphucula ulungelelwaniso kunye nemisebenzi yokuqina kwamathumbu ngelixa ugcwalisa i-antioxidant, i-antifungal, kunye ne-anti-inflammatory factor. Ulwazi olongezelelweyo lubonisiwe ukuba xa abantu befaka ukutya okuvundisiweyo kwizidlo zabo, kunokuphucula impilo yomntu ngokutshintsha inani leebhaktheriya eziluncedo kwinkqubo yamathumbu. Oku kuya kunceda ukubuyisela ukusebenza kweflora yamathumbu kunye nokunceda ukunciphisa ukudumba kwamathumbu umntu ahlangabezana nakho.
isiphelo
Inkqubo yamathumbu inceda ukugcina umzimba usebenza ngokukhulula izondlo kunye neeminerali kumalungu abalulekileyo, izicubu kunye nezihlunu ezinceda ukugcina umzimba uhamba. Inkqubo yamathumbu iphinda inxibelelane ne-immune kunye nenkqubo yobuchopho ekudluliseni ulwazi lokuba ukutya kuguqulwa kube izondlo. Xa umntu ephethwe yimiba yamathumbu kunye nemiphumo yokudumba, eyona ndlela ingcono yokunciphisa ezi mpawu kukutshintsha ngokuthe ngcembe imikhwa yokutya ngokufaka iiprobiotics kunye nokutya okuvundisiweyo kukutya okunempilo ukulungisa inkqubo yamathumbu kunye neendonga zamathumbu. Xa abantu benza olu tshintsho luncinci kwizidlo zabo, inkqubo yabo yamathumbu iya kuzalisa i-flora yamathumbu kwaye ibe nethumbu elonwabileyo.
Ucaphulo
Bell, Victoria, et al. "Impilo enye, ukutya okuvundisiweyo, kunye neGut Microbiota." Ukutya (Basel, Switzerland) , MDPI, 3 Ngomhla wama-2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6306734/ .
Ferraris, Cinzia, et al. "I-Gut Microbiota yeMpilo: Ukutya kunokusigcina njani iGut Microbiota esempilweni?" Amanzi , MDPI, 23 Nov. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7700621/ .
Rinninella, Emanuele, et al. "Amacandelo oKutya kunye neZiqhelo zokuTya: Izitshixo zeMicrobiota ephilileyo yeGut." Amanzi , MDPI, 7 Okt. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6835969/ .
UStiemsma, uLeah T, kunye nabanye. "Ngaba ukutyiwa kokutya okuvundisiweyo kuyayitshintsha i-Human Gut Microbiota?" Umbhalo weZondlo , Oxford University Press, 1 kaJulayi 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7330458/ .
NgoLwesine, uElizabhete, kunye noNathalie Juge. "Intshayelelo kwiMicrobiota yaBantu." Ijenali ye-Biochemical , Portland Press Ltd., 16 May 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5433529/ .
Wieërs, Grégoire, et al. "Indlela iiProbiotics ezichaphazela ngayo iMicrobiota." Imida kwiSellula kunye ne-Infection Microbiology , Imithombo yeendaba yeFrontiers SA, nge-15 Jan. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC6974441/ .
isikhanyeli
by UGqr Alex Jimenez Chiropractic , LweMpilo , I-Gastro Health Intestinal , I-Gut ne-Intestinal Health , I-Viscerosomatic Reflex
intshayelelo
Umzimba womntu ufuna ukutya okunesondlo okunempilo ukunika amandla kwicandelo ngalinye, njengemisipha kunye nezicubu zokuhamba. I Inkqubo yamathumbu ithatha izondlo izise kumalungu ahlukeneyo, iinkqubo, kunye namalungu omzimba adinga ezi zondlo ukuze zisebenze ngokuchanekileyo. Inkqubo yamathumbu nayo ikunxibelelwano ne ngengqondo kwaye i inkqubo yomzimba , apho bathumela ulwazi omnye komnye emva naphambili kwaye bancede umzimba uhlale usempilweni. Xa imiba engapheliyo iqala ukuhlasela inkqubo yamathumbu, inokulahla umzimba ngokubangela ukukrala , ukuphuphuma kweebhaktheriya zamathumbu, kunye neminye imiba yamathumbu enokuchaphazela amathumbu kunye nomzimba. Inqaku lanamhlanje lijonga ukuba ukufumana ukutya okufanelekileyo kunokunceda njani i-gut microbiome kunye nomzimba kunye nendlela amacandelo ahlukeneyo okutya okuchaphazela ngayo i-gut microbiome. Ukubhekisa izigulana kubaboneleli abaqeqeshiweyo, abanezakhono abaziingcali kunyango lwe-gastroenterology. Sikhokela izigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo ibalulekile ekubuzeni imibuzo eqondayo kubaboneleli bethu. UDkt Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli
Ngaba i-inshorensi yam ingayihlawula? Ewe, kunokwenzeka. Ukuba akuqinisekanga, nali ikhonkco kubo bonke ababoneleli beinshorensi esibakhuselayo. Ukuba unemibuzo okanye iinkxalabo, nceda ufowunele uDkt Jimenez kwi-915-850-0900.
Ingaba Ukutya Kunceda Njani Amathumbu?
Ngaba ubuziva uphantsi ngamandla imini yonke? Ngaba ukhe waziva iimpawu zokuvuvukala ezifana ne-acid reflux okanye i-IBS eyenzekayo emathunjini akho? Okanye ngaba uye wavakalelwa kukuba unokuba nolwazelelelo kuhlobo lokutya olukuthandayo? Xa ufumana ezi mpawu rhoqo, kwenzeka ukuba kuchaphazele i-microbiome yakho yamathumbu. Izinto ezininzi zinokuchaphazela i-gut microbiome; ezinye zilungile ngelixa ezinye zimbi. Enye yeempembelelo ezilungileyo kwi-gut microbiome enempilo kukutya okunesondlo. Ukutya kudlala indima enkulu kwi-gut microbiota njengoko inceda ukumisela ukubunjwa kwamathumbu kunye notshintsho. Kuba ukutya kuneyona mpembelelo inamandla kuluntu lwe-microbial esiswini kwimizimba yabantu esempilweni, uphando lophando lufumene I-gut microbiota ithathwa njengenkqubo eguqukayo. Ukubandakanya ukutya okufanelekileyo kunokuba nempembelelo enkulu.
Ekubeni malunga ne-75% yokutya kwi-Western diet eqhelekileyo ilinganiselwe okanye ayinazo izondlo ezinenzuzo kwi-microbiota emathunjini angaphantsi, uninzi lwayo lubandakanya ngokucacileyo i-carbohydrates ecocekileyo esele ifakwe kwi-GI ephezulu. Emva kokuba ukutya kudliwe, ekugqibeleni kuya kufikelela kumathumbu amakhulu aqukethe kuphela amanani amancinci amaminerali afunekayo kunye namavithamini ukugcina i-gut microbiota. Uphononongo olongezelelweyo lophando lufumene ukuba ekubeni iipateni ezahlukeneyo zokutya zihambelana nokwakheka kwe-gut microbiota, kuxhomekeke kwimikhwa yomntu ukubona ukuba yintoni ebasebenzelayo kunye nengenzekiyo xa kufikwa ekutyeni okunempilo.
Iwuchaphazela njani uMzimba?
Uphando lophando lukhankanyile ukuba kunye ne-microorganisms ezininzi kwiphecana le-GI, ukutya okufanelekileyo kunye nomlinganiselo ofanelekileyo weqela lokutya okunomsoco kunokunceda ukulungelelanisa kunye nefuthe kwiprofayili yomzimba we-microbial. Masithi, ngokomzekelo, amaqela amabini awahlukeneyo atya inyama, amaqanda, kunye netshizi usuku olunye aza atshintshela kwiinkozo ezipheleleyo, imifuno, kunye neembotyi ngosuku olulandelayo. Yintoni eyenzekayo kukuba malunga neentsuku ze-1-2, kukho utshintsho oluphawulekayo kwi-gut microbiome eyalinganiswa nge-16S rRNA ngokulandelelana kuwo omabini amaqela. Umsebenzi we-microbial ubonisa umahluko phakathi kwe-herbivorous kunye ne-carnivorous diet, kwaye ibonisa urhwebo phakathi kwe-carbohydrate kunye ne-protein fermentation emzimbeni. Ezinye izifundo zophando nazo zikhankanyile ukuba imikhwa yexesha elide yesondlo isisiseko kwisimo sempilo yomntu kunye nendlela eyibumba ngayo i-gut microbiota.
Yeyiphi indima edlalwa amathumbu kukutya okusempilweni-iVidiyo
VIDEO
Ngaba ubuzama ukutya okunempilo? Ngaba uziva udangele kwaye uphelelwa ngamandla ngokukhawuleza? Ngaba ukhe wanamava obuthathaka bokutya kohlobo lwakho lokutya oluthandayo? Le vidiyo ingasentla ichaza indlela i-gut microbiome edlala ngayo indima yayo xa umntu esitya impilo enempilo. Kuba iintlobo ezahlukeneyo zokutya okunesondlo zihamba kunye ne-gut microbiota, kubalulekile ukwazi ukuba ukudibanisa ukutya okunempilo emathunjini kunokubonelela ngeevithamini eziyimfuneko kunye nezondlo kumzimba wonke. Xa ukhetho olubi luphembelela imikhwa yendlela yokuphila, kuba lucelomngeni ukufumana inkuthazo yokusetha kwakhona umzimba kunye nokubandakanya izondlo eziluncedo ezifunwa ngumzimba. Imikhwa engafanelekanga inokuchaphazela amathumbu ngokubangela ukuvuvukala kunye neminye imiba yamathumbu enokubangela ukuba umntu abe phantsi koxinzelelo kunye neentlungu rhoqo. Ngokufumanisa ukuba yintoni ebangela le miba kunye nokutya ukutya okufunekayo okuzaliswe ngezakhamzimba ezifana neevithamini kunye neeminerali, umzimba kunye namathumbu unokuqalisa ukuphilisa ngokufanelekileyo.
Amacandelo okutya okuchaphazela amathumbu
Kuba i-gut microbiota inoxanduva lokuphembelela umzimba, kubalulekile ukwazi ukuba zeziphi izinto ezigaywayo emathunjini ezinokuchaphazela ngokuthe ngqo umntu. Ukusukela oko uphando lophando lufumene ukuba ukutya okunempilo sesinye sezimodyuli ezibalulekileyo eziphembelela ngokuthe ngqo ukwakheka kwe-microbial yamathumbu ngokuguqula ngokupheleleyo inkqubo yebhayoloji yokubilisa izondlo kunye nokuchaphazela imisebenzi yesithintelo samathumbu. Ukunyuka kweziqhamo, imifuno, kunye nokusetyenziswa okuphezulu kwefayibha kunxulunyaniswa nobutyebi bebhaktheriya emathunjini aphezulu. Uphando olongezelelweyo lubonelele ukuba abantu abohlukeneyo kwi-microbial yamathumbu banokude balamle isiphumo esiluncedo sokubilisa iintsinga zokutya ukuvelisa ii-SCFAs (i-short-chain fatty acids) ukunciphisa iziphumo zokudumba emathunjini. Ezinye iinxalenye zezondlo ezinokuchaphazela amathumbu ziquka:
Ukutya kwezityalo protein I-Polyunsaturated Fatty Acids kunye ne-CLA (ecetywayo) I-carbohydrate
IFayibha enyibilikayo/eNganyangekiyo Isitatshi (iMicrobiotaaccessible carbohydrate =MACS)
iswekile Prebiotics Polyphenols Ukutya okuKhulisiweyo kunye noKuvundisiweyo
isiphelo
Ukubandakanya ukutya okunempilo kunokubonelela ngempembelelo enenzuzo kwi-gut microbial system. Xa izinto ezingafunekiyo ezifana nokungahambi kakuhle, ukutya okungenampilo, uxinzelelo, kunye nemiba yamathumbu iqala ukuchaphazela umzimba, inokubangela ukuba umntu abe nentlungu kwaye achaphazele impilo yakhe yonke. Ukwenza utshintsho oluncinci kunokuba nempembelelo enkulu kumntu xa ezama ukuba nempilo kwaye abuyisele ubomi bakhe. Xa udibanisa ukutya okupheleleyo, umzimba uya kuqala ukuziphilisa ngokufanelekileyo, kwaye umntu uya kuba namandla amaninzi kuhambo lwakhe lwezempilo kunye nokuphila kakuhle.
Ucaphulo
UConlon, uMichael A, kunye no-Anthony R Bird. "Impembelelo yokutya kunye nendlela yokuphila kwi-Gut Microbiota kunye neMpilo yoLuntu." Amanzi , MDPI, 24 Ngomhla wama-2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4303825/ .
Ferraris, Cinzia, et al. "I-Gut Microbiota yeMpilo: Ukutya kunokusigcina njani iGut Microbiota esempilweni?" Amanzi , MDPI, 23 Nov. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7700621/ .
Hills, uRonald D, kunye no-al. "I-Gut Microbiome: Iimpembelelo ezinzulu kukutya kunye neSifo." Amanzi , MDPI, 16 Julayi 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6682904/ .
Leeming, Emily R, et al. "Impembelelo yokutya kwi-Gut Microbiota: Ukucinga kwakhona ukungenelela ngexesha." Amanzi , MDPI, 22 Nov. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6950569/ .
Moszak, Małgorzata, et al. "Uyinto oyityayo-ubudlelwane phakathi kokutya, iMicrobiota, kunye nokuphazamiseka kweMetabolic-Uphononongo." Amanzi , MDPI, 15 kuMatshi 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7230850/ .
Rinninella, Emanuele, et al. "Amacandelo oKutya kunye neZiqhelo zokuTya: Izitshixo zeMicrobiota ephilileyo yeGut." Amanzi , MDPI, 7 Okt. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6835969/ .
isikhanyeli
by UGqr Alex Jimenez Chiropractic , I-Gastro Health Intestinal , I-Gut ne-Intestinal Health , I-Viscerosomatic Reflex
intshayelelo
The Inkqubo yamathumbu likhaya kwiibhaktheriya ezininzi eziluncedo eziqinisekisa ukuba yonke into isebenza ngokuchanekileyo. Amalungu enza inkqubo yamathumbu ancedisa ukuthutha izondlo kunye negazi eline-oxygen kwimisipha, izicubu, iinqanawa kunye neengcambu zemithambo-luvo ezivumela umzimba ukuba usebenze. Amathumbu nawo anxibelelana ne ngengqondo kwaye i inkqubo yomzimba ukunika amandla ayimfuneko ukwenza umzimba uhambe ukusuka kwindawo ukuya kwenye. Xa izinto eziphazamisayo ziqala ukuphazamisana ne-gut microbiota, kunokubangela izinto ezivuthayo kunye neminye imiba enxulumene namathumbu ukutshabalalisa iindonga zamathumbu emathunjini kwaye zichaphazele impilo yonke yomntu. Inqaku lanamhlanje lizakugxila kwindima ye-gut microbiome emzimbeni, ukusebenza kwemetabolism yeebhaktheriya zamathumbu, kunye nendlela izinto ezahlukeneyo ezinokuchaphazela ngayo amathumbu ekusebenzeni ngokuchanekileyo. Ukubhekisa izigulana kubaboneleli abaqeqeshiweyo nabanezakhono abaziingcali kunyango lwe-gastroenterology. Sikhokela izigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo ibalulekile ekubuzeni imibuzo ecacileyo kubaboneleli bethu. UDkt Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli
Ngaba i-inshorensi yam ingayihlawula? Ewe, kunokwenzeka. Ukuba akuqinisekanga, nali ikhonkco kubo bonke ababoneleli beinshorensi esibakhuselayo. Ukuba unemibuzo okanye iinkxalabo, nceda ufowunele uDkt Jimenez kwi-915-850-0900.
Indima yeGut Microbiome eMzimbeni
Ngaba ubuziva ugula sisisu sakho? Ngaba uziva udumbile kumbindi wecandelo lomzimba wakho? Ngaba uziva unovelwano kukutya obukutyayo? Uninzi lwezi mpawu yimiba enxulumene namathumbu echaphazela i-gut microbiome. I-gut microbiota idlala indima ebalulekileyo ye-metabolic kwiinkqubo ezininzi ezinceda ukugcina umzimba usebenza ngokugcina ulungelelwano oluthambileyo kunye nokuthetha ngokunqamlezayo kunye ne-immune system. Izifundo zophando zibonisile ukuba i-gut microbiome ilikhaya kuluntu oluntsonkothileyo kwaye oluguquguqukayo lwezityalo zamathumbu eziphembelela umzimba. Kuba i-gut microbial ecosystem ithathwa njengelona lungu likhulu le-endocrine emzimbeni, inokuvelisa iikhompawundi ezahlukeneyo zebhayoloji ezisebenza ngokufanayo neehomoni. Ezi khompawundi zithwalwa ngokujikeleziswa kwaye zisasazwe kwiindawo ezikude ngaphakathi komkhosi, ziphembelela iinkqubo zebhayoloji ezibalulekileyo ezahlukeneyo. Ezinye izifundo zophando zikhankanyile ukuba i-intestinal tract in the body intestinal ecosystem ecosystem enokuphenjelelwa zizinto ezininzi ezichaphazela i-gut microbiome ekubunjweni kwayo kunye notshintsho. Olunye lolu tshintsho lunceda ukukhula kakuhle kwebhaktheriya kwi-gut microbiota.
Umsebenzi weMetabolic weBacteria emathunjini
Xa umntu esitya ukutya okunesondlo, uhamba emathunjini ukuze abe biotransformed zibe izondlo. Yenza indlela yayo emathunjini, apho igcinwa kwaye ilungele ukuhanjiswa kuwo wonke umzimba. Xa ukutya kokugaya kuhleli emathunjini, kulapho ibhaktheriya enenzuzo yamathumbu ingena kwaye inceda ukubumba i-gut microbiota. Izifundo zophando zibonisile ukuba iibhaktheriya eziluncedo emathunjini zidlala indima ebalulekileyo kwi-gut microbiome njengoko inceda ukugcina i-immune kunye ne-homeostasis ye-metabolic. Umsebenzi we-metabolism yebhaktheriya emathunjini emzimbeni inceda ukophula iifayibha zokutya ezithi emva koko zijike zibe zii-SCFAs (iiasidi ezinamafutha amafutshane). Eminye imisebenzi eyenziwa yintsholongwane yamathumbu kwi-gut microbiome ibandakanya:
Ukuveliswa kweePhenols Ukuchithwa kwe-oligosaccharides Inceda ukulawula Amafutha, TG, kunye neCholesterol Ukufunxa iivithamini Ukuveliswa kwe-mucous Ukuxutyushwa
Isishwankathelo sevidiyo ehlukeneyo yeGut
VIDEO
Ngaba ubuziva utyhafile imini yonke? Ngaba uziva uqhinile okanye udumbile? Ngaba uye wanovelwano ngokutya okuthandayo? Ukuba ubujongene nale miba kubomi bakho bonke, inokuba kungenxa ye-microbiome yakho yamathumbu ethetha nawe. Le vidiyo ingasentla icacisa indlela i-gut microbiome lelinye lamalungu abalulekileyo emzimbeni kuba inceda kwizinto ezahlukeneyo zebhayoloji kwinkqubo yamathumbu. Ukubaluleka kokwahlukahlukana okukhulu kweentsholongwane kunxulunyaniswa namandla omzimba okujongana noxinzelelo, njengeentsholongwane ezithatha amathuba okanye ukuphazamiseka kokutya okuchaphazela inkqubo yokwetyisa. Xa abantu benezifo ezinxulumene namathumbu, kunokwenzeka ukuba batshintshe i-microbiome yabo yamathumbu kunabantu abasempilweni. Ubudlelwane obuninzi phakathi kokuncipha kweyantlukwano ye-microbial kunye nokugula zirekhodwa kuncwadi ukuze abantu bafumanise ukuba kuqhubeka ntoni kwinkqubo yabo yamathumbu. Ukugcina amathumbu asempilweni kunokuthintela imingcipheko efana nezifo ze-metabolic ezifana nohlobo lwe-2 yeswekile, i-IBD (isifo samathumbu esivuthayo), i-SIBO, kunye nezinye izinto ezibeka ingozi emathunjini ekuchaphazeleni amathumbu.
Izinto ezinokuchaphazela iThumbu
Xa kukho imeko yokungalingani kwe-microbial ecology enegalelo ekuchaphazeleni umlinganiselo weebhaktheriya zamathumbu, kunokubangela izifo ezininzi ezingapheliyo ezibangela ukuba umzimba ungasebenzi. Ukukhula okugqithisileyo kwezilwanyana ezincinci kwintsholongwane ephantsi ye-intrinsic virulence kubangela isifo ngokuguqula:
Ubume besondlo Ukusabela komzimba Amandla okuphelisa umamkeli
Izifundo zophando zifumene ukuba izinto ezichaphazela i-gut microbiome zinokubangela iindlela zokukrala ezihlasela iindonga zamathumbu kwaye zivumele ibhaktheriya ukuba iphume. Ezinye izinto ezinje ngoxinzelelo okanye ukugqabhuka ngokweemvakalelo kunokubangela ukukhula kweebhaktheriya eziyingozi ukuba zigqithise iibhaktheriya ezilungileyo. Oku kubangela ukuba i-gut microbiome ingasebenzi kwaye iqhubele phambili kwimiba engapheliyo yamathumbu. Ezinye izifundo zophando zibonisile ukuba izinto zokusingqongileyo zikwadlala indima ekuguquleni i-gut microbiome. Ezi zinto zibangela utshintsho olungafunwayo olunokumenzakalisa umntu engazi nokwazi. Ukubonisa ukuba zeziphi izinto ezichaphazela amathumbu zinokuthintelwa xa umntu ebeka umsebenzi wokuphucula impilo yakhe.
isiphelo
Njengoko bekutshiwo ngaphambili kwinqaku lanamhlanje, i-gut microbiome ithathwa njengelona lungu likhulu le-endocrine elinceda ukuqinisa amajoni omzimba kunye ne-homeostasis emzimbeni. Ke ngoko, ukuzalisa i-gut microbiome ngeebhaktheriya eziluncedo kunokunceda ukusombulula uninzi lwemiba engapheliyo echaphazela umzimba. Xa izinto zokusingqongileyo zibangela umonakalo kwinkqubo yamathumbu, inokuchaphazela wonke umzimba ukuba awuphathwa ngoko nangoko. Ukuphelisa izinto eziyingozi zokusingqongileyo kubomi bemihla ngemihla bomntu kunokubonelela ngesiqabu ebesisoloko besifuna.
Ucaphulo
Al Bander, Zahraa, et al. "I-Gut Microbiota kunye noKudumba: Isishwankathelo." Ijenali yehlabathi yoPhando lwezeNdalo kunye neMpilo yoLuntu , MDPI, 19 Okt. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7589951/ .
UDurack, uJuliana, kunye noSusan V Lynch. "I-Gut Microbiome: Ubudlelwane Nezifo kunye namathuba oNyango." Ijenali yoMfuniselo woNyango , Rockefeller University Press, 7 Jan. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6314516/ .
Ferraris, Cinzia, et al. "I-Gut Microbiota yeMpilo: Ukutya kunokusigcina njani iGut Microbiota esempilweni?" Amanzi , MDPI, 23 Nov. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7700621/ .
ULobionda, uStefani, kunye nabanye. "Indima ye-Gut Microbiota kwi-Intestinal Inflammation ngokumalunga nokutya kunye neeStressors zangaphandle." Iintsholongwane , MDPI, 19 Agasti 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6722800/ .
NgoLwesine, uElizabhete, kunye noNathalie Juge. "Intshayelelo kwiMicrobiota yaBantu." Ijenali ye-Biochemical , Portland Press Ltd., 16 May 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5433529/ .
isikhanyeli
by UGqr Alex Jimenez Chiropractic , LweMpilo , I-Gastro Health Intestinal , I-Gut ne-Intestinal Health , nezongezo , I-Viscerosomatic Reflex
intshayelelo
Ngaphakathi emzimbeni kulele amalungu angaphakathi abonelela ngezondlo kunye namandla ukuze umzimba uhlale ushukuma. I Inkqubo yamathumbu inceda amandla omzimba ngokwetyisa ukutya okutyiweyo okujikwa kube ngamandla kunye nezondlo eziluncedo kumalungu abalulekileyo, izihlunu, izicubu kunye nokukhula okudingwa ngumzimba. Inkqubo yamathumbu ikwanceda ukulawula ezinye iinkqubo zomzimba ezifana ne inkqubo yemisipha , i inkqubo yomzimba , kwinkqubo yomnatha , kwaye i inkqubo ye endocrine . Inkqubo yamathumbu isebenza ngokuhambisa ezi zondlo ukwenza umzimba usebenze, ukukhankanya iimfuno ezimbalwa. Xa imiba engafunekiyo iqala ukungena kwinkqubo yamathumbu kwaye ibangele ukuphazamiseka, kunokukhokelela kwiingxaki ezininzi ezingapheliyo eziza kubangela ukuba umzimba ube neentlungu eziqhubekayo ngelixa ubangela ezinye izinto ezichaphazela umzimba wonke. Inqaku lanamhlanje liza kujonga ukuba imiba yamathumbu eyahlukileyo iqala njani ukuchaphazela umzimba kunye nokuba i-amino acid ebizwa ngokuba yi-glutamine inokubonelela njani ngesiqabu kwimiba eyahlukeneyo yamathumbu. Ukubhekisa izigulana kubaboneleli abaqeqeshiweyo nabanezakhono abaziingcali kunyango lwe-gastroenterology. Sikhokela izigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo ibalulekile ekubuzeni imibuzo ecacileyo kubaboneleli bethu. UDkt Alex Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli
Ngaba i-inshorensi yam ingayihlawula? Ewe, kunokwenzeka. Ukuba akuqinisekanga, nali ikhonkco kubo bonke ababoneleli beinshorensi esibakhuselayo. Ukuba unemibuzo okanye iinkxalabo, nceda ufowunele uDkt Jimenez kwi-915-850-0900.
Indlela Imiba Yamathumbu Ewuchaphazela Ngayo Umzimba
Ngaba ukhe waziva iintlungu ezibekwe emathunjini akho? Ngaba amathumbu akho abonakala ebuthathaka ngakumbi emva kokutya ukutya? Ngaba ukhe wanexhala okanye ucinezelekile ukuba ibichaphazela umzimba wakho? Ukufumana ezi mpawu ziimpawu zokuba unokuba nemiba yamathumbu echaphazela umzimba wakho. Izifundo zophando zifumene ukuba imiba yamathumbu okanye iziphazamiso zidla ngokukhula xa amathumbu ethe avelisa ngaphantsi okanye avelisa kakhulu iibhaktheriya zamathumbu eziluncedo ezinokuphembelela iibhaktheriya eziyingozi ukuba zihlasele iindonga zamathumbu. Imiba yamathumbu nayo inokuphenjelelwa ngenxa yokhetho lwendlela yokuphila okanye ukuphazamiseka kwe-autoimmune okuchaphazela amathumbu kunye nawo wonke umzimba kunye neenkqubo zawo. Ulwazi olongezelelweyo lufunyenwe ukuba xa i-microbiome icelwa umngeni ngezinto ezitshintsha i-physiology ye-gut microbiome. Olu tshintsho luya kubangela ukunyuka kwamathumbu emathunjini, okuvumela ukuba iibhaktheriya ezinobungozi ziphume, ezibangela ukuba i-immune system ihlasele iibhaktheriya eziveziweyo kwiindonga zamathumbu ezikhokelela kwimiba evuthayo.
Olunye uphononongo lophando lufumene ukuba ibhaktheriya yamathumbu ibonelela ngendima ebalulekileyo emzimbeni njengoko inceda ukubonelela ngezondlo ezibalulekileyo eziluncedo kwimpilo yomzimba. Xa utshintsho olungaqhelekanga luchaphazela ibhaktheriya yamathumbu, i-ecosystem ye-gut ikhawuleza i-dysbiosis, ibangela imiba emininzi engapheliyo. Abantu abaninzi baya kuqala ukuphulukana nomgangatho wabo wobomi ngenxa yeentlungu. Ngethamsanqa, kukho iindlela zokunciphisa imiba engapheliyo echaphazela amathumbu kwaye uncede ukuthoba ibhaktheriya eyingozi ngokuzalisa iibhaktheriya eziluncedo ngelixa unciphisa iimpawu zokukrala.
Isishwankathelo malunga ne-Glutamine-Ividiyo
VIDEO
Ngaba ukhe waneengxaki ezichaphazela amathumbu akho? Ngaba indawo yakho ye-torso ibiziva ithenda xa ubamba? Kuthekani ngamabala eentlungu angaqhelekanga akwisisu sakho? Unokuba neengxaki zamathumbu ezichaphazela impilo yakho yonke kunye nokuphila kakuhle. Kutheni ungafaki i-glutamine kwisongezelelo sakho semihla ngemihla. Uphononongo lophando lukhankanyiwe ukuba i-glutamine i-amino acid eneempawu eziluncedo ekuzaliseni amajoni omzimba kunye nokuxutywa kwe-metabolizing emathunjini kunye namanye amalungu abalulekileyo adinga i-glutamine ukondla isakhiwo seselula ukuze umzimba uzive ungcono kwaye unike amandla kubantu abaninzi. Ividiyo engentla ibandakanya ulwazi malunga neenzuzo ze-glutamine kunye nendlela enokunceda ngayo umzimba.
Inceda njani iGlutamine emathunjini
Njengoko bekutshiwo ngaphambili, i-glutamine yi-amino acid eneempawu eziluncedo ezisetyenziselwa ukunika amandla kuwo wonke umzimba. Izifundo zophando zibonisile ukuba i-glutamine kwinkqubo yamathumbu inokugcina ukwakheka kwamathumbu kunye nokusebenza njengoko umzimba uguga ngelixa ulawula iiprotheni ezidibeneyo. I-Glutamine ikwancede ekumodareyitheni impembelelo yamathumbu emathunjini oxinzelelo lwe-HPA-axis echaphazela amathumbu kwaye ikhusela iiseli kwi-apoptosis kunye noxinzelelo lweselula. Izifundo zophando ezongezelelweyo zibonelele ukuba xa abantu bethatha i-glutamine njengenxalenye yolawulo lwabo lwemihla ngemihla, baya kuba nempendulo engcono yokuvuvukala kunye nokulinganisela kwe-redox emathunjini kunye nokudibanisa imisebenzi yomzimba. Ukusebenzisa i-glutamine kwimpilo yamathumbu kunokuncedisa ukuphucula ukusebenza kwamathumbu kunye nomsebenzi wokungena kwesisu kubantu abaninzi bezemidlalo.
isiphelo
Ngokubanzi, inkqubo yamathumbu isebenzisa i-glutamine kwimpilo yamathumbu egqwesileyo ekudambiseni iziphumo zemiba yamathumbu kunye nokuphazamiseka okuya kuchaphazela umzimba. Amathumbu abonelela ngokuthuthwa kwezondlo ezibalulekileyo kuzo zonke iinkqubo zomzimba ezifuna ukuba zisebenze ngokuchanekileyo. Xa izinto ezingafunekiyo okanye iindlela zokuphila ezingafanelekanga zichaphazela inkqubo yamathumbu, inokunyusa ibhaktheriya eyingozi emathunjini kwaye inciphise ibhaktheriya enenzuzo. Oku kuya kubangela ukuba i-cytokines evuthayo ihlasele iindonga zokungena emathunjini kwaye ibangele imiba emininzi eya kuchaphazela umzimba. Izongezo eziluncedo kunye nezondlo ezinceda ukuthomalalisa izinto ezibangela ukudumba okanye ukunciphisa imiba yamathumbu zikhona ukuze zibonelele ngesiqabu ngokuthomalalisa ezi ziphumo ziyingozi kunye nokulungisa umzimba. Ukubandakanya i-glutamine emathunjini akho kuya kunceda umzimba ukuba uphinde ubuyele emva kwexesha kwaye ungabi nazintlungu.
Ucaphulo
U-Almeida, u-Ewin B, kunye no-al. "I-L-Glutamine Supplementation iPhucula iiNzuzo zoQeqesho oluDityanisiweyo lokuSebenza kwi-Oral Redox ibhalansi kunye neSimo sokuvuvukala kubantu abadala." Unyango lwe-Oxidative kunye nokuPhila ixesha elide , Hindawi, 22 Jan. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7204202/ .
UClapp, uMegan, kunye nabanye. "Impembelelo yeGut Microbiota kwiMpilo yengqondo: I-Gut-Brain Axis." Iiklinikhi kunye nokuziqhelanisa , IPHEPHAPress Scientific Publications, Pavia, Italy, 15 Sept. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5641835/ .
Cruzat, Vinicius, et al. "I-Glutamine: I-Metabolism kunye noMsebenzi woMzimba, uLwaniso kunye noGuqulelo lweKlinikhi." Amanzi , MDPI, 23 Okt. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6266414/ .
UKim, uMin-Hyun, kunye noHyeyoung Kim. "Iindima zeGlutamine emathunjini kunye nefuthe layo kwizifo zamathumbu." I-International Journal ye-Molecular Sciences , MDPI, 12 Meyi 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5454963/ .
Nouvenne, uAntonio, et al. "Ukuphazamiseka kokutya kunye neMicrobiota yamathumbu." IActa Bio-Medica: Atenei Parmensis , Mattioli 1885, 17 Dec. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6502202/ .
Zhang, Yu-Jie, et al. "Iimpembelelo zeBacteria emathunjini kwiMpilo yabantu kunye neZifo." I-International Journal ye-Molecular Sciences , MDPI, 2 kuMatshi 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4425030/ .
isikhanyeli
