I-Bifidobacteria kunye neNkqubo ye-Gut

Ngaba uziva:

• Ubuhlungu besisu, ukutsha, okanye ukuqaqanjelwa kwe1-4 iiyure emva kokutya?
• Ngaba iingxaki zokutya zidla ngokuphumla okanye ukuphumla?
• Ukuqunjelwa kunye nokuzaliswa kudlule iiyure ezingama-2-4 emva kokutya?
• Ngaba ugobe kakhulu, ukugqobhoza, okanye ukuqhuma?
• Ukucaphuka kwesisu emva kweeprobiotic ezithile okanye izongezo zendalo?

Ukuba uhlangabezana nazo naziphi na kwezi meko, ke oko kungabangelwa kukuncipha kwenkqubo yakho yeBifidobacteria.

I-microbiome yomzimba likhaya kwiintlobo ezininzi zebhakteriya ezinceda ukuba negalelo kwizinto zazo ezikhuthaza impilo. Ezi ntlobo zebhakteriya zinceda umzimba ngokuqinisekisa ukuba ilungu ngalinye kunye nenkqubo yomzimba isebenza njengewotshi. Xa umzimba uqukethe iibhaktheriya eziyingozi ze-pathogenic, unokubangela ukungasebenzi kakuhle emzimbeni, kwaye izifo ezinganyangekiyo ziya kuqala ukubumba zize zonakalise umzimba.

Izifundo zophando zifumene ukuba inani leentlobo zebhaktiriya ezikwi-gut microbiota yomntu lingadlula kwi-10⁴. Oku kuthetha ukuba ubuncinci iishumi zeebacteria ezingaphezulu kweyishumi kwisisu somntu kunenani leeseli zabantu. Kukho nangaphezulu kwamaxesha ali-100 inani le-genomic microbiome njenge-genome yomntu. Kuyamangalisa, nangona kunjalo nezifundo ezingaphezulu ifumanise ukuba kukho umlinganiso olinganayo wabantu kwiiseli zebacteria.

IBifidobacteria

Nokuba lithini na inani, isisu esiswini sinobona bunzima obuninzi obuninzi emzimbeni. Xa amathumbu kunye nomzimba ulungelelene kakuhle, kukho iindidi ezahlukeneyo zeetsholongwane ezinokuthi zinike umzimba womelele kwaye womeleze enokuxhasa amajoni omzimba, ulwe nosulelo olungene emzimbeni. Iintsholongwane zinokubonelela esiswini esisithintelo kwiintsholongwane, kwaye sincede ekufukuleni nasekuveliseni izakha mzimba ezibalulekileyo ukuze umzimba usebenze. Ngamanani amaninzi eentlobo zebhakteria kuwo omabini esiswini kunye nomzimba, kukho enye yeentlobo zebhakteriya ebaluleke kakhulu kumzimba osempilweni. Yaziwa ngokuba yiBifidobacteria, kwaye ezi ntlobo zebhakteria zidlala indima enkulu kwi-micobiome yomzimba.

I-Bifidobacteria luhlobo lwendabuko lwendalo oluyintabalala yale ntlobo yebhaktiriya elele esiswini, kwaye amanani ayo, kunye nohlobo lwazo, anokutshintshwa ngobudala. I-Bifidobacteria ilawulwa ngokuqaqambileyo emathunjini. Kuyamangalisa, nangona kunjalo, iintlobo zeBifidobacteria zingafunyanwa kwiintsana ezincancisiweyo kwaye zikwamathumbu. Kuba i-oligosaccharides ye-fucosylated kubisi lwebele inceda umntwana ukuba akhule, iya kuba yindawo ephantsi kwe-B ubude. Nge-Bifidobacteria colony kwiintsana ziye zaqhelaniswa kakuhle de indalo B. catenulatum kunye no-B. tegenis apho ikhoyo kwiminyaka yobudala, kwaye kubonakala ngathi iB.B longum ihlala iyintabalala kulo lonke ixesha lobomi bomntu.

Izibonelelo zeBifidobacteria kwiintsana

Xa umntu obhinqileyo ekhulelwe, iBifidobacteria iba luhlobo lokuqala lwebhaktiriya ezigqithiselweyo. Le bacterium iqinisekisa ukuba idluliselwa kumngxunya wesibeleko sowesifazane, ubisi lwebele, iplacenta, kunye neamniotic fluid ukuya kumntwana okhula kumama. Xa le nkqubo ithatha inkqubo, ibalaselisa ukubaluleka kokuzalwa kunye nokuncancisa ukumisela isetyhula esempilweni. Uphando lubonisa ukuba oku kusungulwa kweBifidobacteria elusaneni kungalibazisa ukuba umama womntwana okhulayo une-polymorphism ku-FUT2 (Fucosyltransferase 2) gene. Into eyenziwa yile gene kukuba ifaka i-enzymes ukuhambisa i-fucose kwi-glycans kwisibele, emva koko i-glycan ke ilungiswa yi-Bifidobacteria ukuze umzimba ukhule kwaye ube sempilweni.

Izifundo zifumene ukuba kwezinye iintlobo ze-Bifidobacteria ezifana neB. breve, zinezinto ezibulala into kunye nezifo ezibaluleke kakhulu kumanqanaba obomi bomzimba womntu apho amajoni omzimba anganakho ukuthamba okanye nokuba sengozini. Kwiintsana, iintlobo zeBifidobacteria zibaluleke ngakumbi, kuba ziyanceda ngokuphuhliswa komzimba omtsha kwaye azikwazi ukudlulisela ukunganyangekiyo ngamayeza okubulala iintsholongwane. Oku kungabhekisa kwezinye zeentlobo ezithile zemvelo emzimbeni. Kunye neentlobo zeebhakteria zohlobo lweB. Izifundo zifumene ukuba ezi ntlobo zebhaktiriya zibalulekile ekuthinteleni iimeko ezininzi zesisu kubantwana.

Izibonelelo zeBifidobacteria kuBantu abadala

Xa kuziwa kwi-Bifidobacteria kubantu abadala, inani labo lebhakteria liyancipha ngenxa yokuguga kwendalo. Nangona kunjalo, i-Bifidobacteria isabonelela ngexabiso elilinganayo lezinto ezizuzisayo ezikhupha inani lemisebenzi yezinto eziphilayo ezinokuthi zithintele ezinye iimeko eziqhelekileyo zesisu. Izifundo zibonise ukuba i-Bifidobacteria ingabonisa iziphumo ezithembisayo zokuthintela umhlaza webala kwaye inokusetyenziswa njengonyango lwe-adjunct. Izifundo zide zibonise ukuba i-Bifidobacteria ingawubonisa njani umsebenzi we-anti-mutagenic, ukukhusela i-DNA kumonakalo obangelwa yi-carcinogen, kunye nokuthintela iziphumo ze-genotoxic ze-carcinogen.

Olunye uphando lubonakalisile ukuba i-Bifidobacteria inokuthintela kwaye inciphise urhudo olubangelwa yiClostridium ubunzima. Iziphumo zibonisa ukuba unyango lweBifidobacteria lunokulinciphisa kakhulu inani leecostridial toxin titres.

isiphelo

I-Bifidobacteria luhlobo olukhulu lweebacteria oluxanduva lokugcina umzimba usempilweni kunye nenkqubo ye-gut. Xa umzimba ujongene nokuvuvukala okanye unemicimbi yesisu, ke uhlobo lwe-bifidobacterial genus luya kuchaphazeleka. Le ntsholongwane isemzimbeni womntu ukusuka ebusaneni ukuya ebudaleni, kwaye iya kuncipha ngokwemvelo ngokwaluphala. Abanye iimveliso zenzelwe ukunceda inkqubo yesisu kunye nenkqubo yamathumbu ngokubonelela ngesondlo se-hypoallergenic, i-enzymatic cofactors, umphambili we-metabolic, kunye ne-phytonutrients ekufuneka umzimba.

Ubungakanani bolwazi lwethu lukhawulelwe kwi-chiropractic, musculoskeletal, kunye nemicimbi yezempilo yovalo okanye amanqaku amayeza asebenzayo, izihloko kunye neengxoxo. Sisebenzisa iiprothokholi zempilo ezisebenzayo ukunyanga ukwenzakala okanye ukuphazamiseka kwenkqubo yemusculoskeletal. Iofisi yethu yenze umzamo oqinisekileyo wokubonelela ngezikhokelo ezixhasayo kwaye ichonge isifundo sophononongo esifanelekileyo okanye izifundo ezixhasa izithuba zethu. Sikwenza iikopi zezifundo zophando ezixhasayo ziya kufumaneka ebhodini okanye kuluntu xa luceliwe. Ukuqhubeka nokuxoxa ngomxholo ongentla, nceda ukhululeke ukubuza uGqirha Alex Jimenez okanye unxibelelane nathi apha 915-850-0900.

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Iingxelo:

Arboleya, Silvia, et al. �IGut Bifidobacteria Abemi kwiMpilo yoLuntu kunye nokuguga.� Imida kwi Microbiology, Frontiers Media SA, 19 Aug. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4990546/.

Bozzi Cionci, Nicole, et al. �Unyango lweMicrobiology: Indima ye I-Bifidobacterium Breve njengeSongezo sokuTya kuThintelo/noNyango lweZigulo zaBantwana.� Amanzi, MDPI, 10 Nov. 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6265827/.

O'Callaghan, Amy, kunye noDouwe van Sinderen. �Bifidobacteria kunye nendima yabo njengamalungu eHuman Gut Microbiota.� Imida kwi Microbiology, Frontiers Media SA, nge-15 kaJuni ngo-2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4908950/ #

Iqela, DFH. �Iziseko zeBifidobacteria.� Uyilo lwezeMpilo, I-5 Septemba. 2019, blog.designsforhealth.com/node/1100.

Thursby, Elizabeth, kunye Nathalie Juge. �Intshayelelo kwiHuman Gut Microbiota.� Ijenali ye-Biochemical, EPortland Press Ltd., nge-16 kaMay 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5433529/.

Wei, Yanxia, ​​et al. �Iimpembelelo zoKhuseleko lweBifidobacterial Strains ngokuchasene neToxigenic IClostridium Difficile. Imida kwi Microbiology, I-Frontiers Media SA, nge-8 kaMeyi 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5952185/.

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