Umsebenzi we-Nrf2 Ukuqalisa

Uninzi lweengxelo zophando ngokuphathelele umdlavuza ziye zavumela ootitshala bezempilo ukuba baqonde indlela umzimba uchithe ngayo. Ngokuhlalutya izakhi zofuzo ezisemgangathweni kwiiseli ezixhamlayo, abaphandi bafumene i-nyukliya erythroid I-2 enxulumene ne-2 yokubonisa indlela, eyaziwayo njengeNrf2. I-NRF2 yinto ebalulekileyo yenguqu ebhaliweyo eyenza umzimba womzimba iindlela zokukhusela i-antioxidant ukuze kulawulwe i-oxidation kwizinto zombini zangaphakathi kunye zangaphakathi ukukhusela amanqanaba okwandisa uxinzelelo.

Iimigaqo zeNrf2

I-NRF2 ibalulekile ekugcineni impilo yonke nokuba sempilweni kwayo kuba iyayisebenzisa eyona njongo iphambili yokulawula indlela esilawula ngayo yonke into esijongana nayo yonke imihla kwaye singaguli. Ukusebenza kwe-NRF2 kudlala indima kwinkqubo yesixokelelwano sokuxutywa kwentsholongwane. Kwinqanaba I.

Ukusebenza kwe-NRF2 kuncitshisa i-oxidation jikelele kunye nokuvuvukala komzimba womntu ngefuthe elibi. Ukubangela i-NRF2, ukuphendula okuvuthayo ngenxa ye-oxidation kufuneka kwenzeke ukwenzela ukuba iiseli zivelise impendulo eguquguqukayo kwaye zenze i-antioxidants, njenge glutathione. Ukuphula umgaqo we-Nrf2, ngokukodwa, ukunyanzeliswa kwengcinezelo kusebenze i-NRF2 leyo leyo isebenzayo impendulo ye-antioxidant emzimbeni womntu. Imisebenzi ye-NRF2 ukulinganisela ukubonakaliswa kwe-redox, okanye ukulingana kwamanqanaba akhuphayo kunye ne-antioxidant kwiseli.

Umzekeliso omkhulu wendlela le nkqubo isebenza ngayo ingabonakaliswa ngokwenza umthambo. Kuwo wonke umsebenzi, umsipha uhlengahlengiso ukuze ukwazi ukufumana enye iseshoni yokuzilolonga. Ukuba i-NRF2 iba ngaphantsi okanye ichazwe ngaphezulu ngenxa yosulelo olunganyangekiyo okanye ukonyuka kokuvezwa kwetyhefu, enokuthi iqatshelwe kwizigulana ezinesifo esinganyangekiyo sokuphendula ngokudumba, okanye i-CIRS, imiba yezempilo inokuba mandundu - ngokulandela ukusebenza kwe-NRF2. Ngaphezu kwako konke, ukuba i-DJ-1 iba ne-oxidized engaphezulu, ukusebenza kwe-NRF2 kuya kuphela ngokukhawuleza.

Iimpembelelo ze-NRF2 Ukuqalisa

Ukusebenza kwe-NRF2 kubonakaliswe kakhulu kwimiphunga, isibindi kunye neentso. I-nuclear erythroid i-2 enxulumene ne-2, okanye i-NRF2, ngokuqhelekileyo isebenza ngokunciphisa amanqanaba okwanda kwe-oxidation emzimbeni womntu onokubangela uxinzelelo lwe-oxidative. Ukuqalisa ukusebenza kwe-Nrf2 kunokunceda ukuphatha iinkalo ezahlukeneyo zempilo, nangona kunjalo, ukusetyenziswa ngokugqithiseleyo kwe-Nrf2 kunokudambisa iingxaki ezahlukeneyo, eziboniswa ngezantsi.

Ukusebenza kwesikhashana kweNrf2 kunokukunceda:

• Ukuguga (oko kukuthi ubude)
• Ukuzimela ngokuzenzekelayo kunye nokuvutha okubanzi (oko kukuthi iArthritis, Autism)
• I-Cancer kunye ne-Chemoprotection (oko kukuthi i-EMF Exposure)
• Ukuxinezeleka kunye nokuxhalabisa (oko kukuthi i-PTSD)
• Ukuboniswa kweziyobisi (i-Alcohol, i-NSAID)
• Ukuzivocavoca nokuSebenza koMonde
• Izifo ze-Gut (ie i-SIBO, iDysbiosis, Ulcerative Colitis)
• Izifo Zeengso (oko kukuthi Kukho ukulimala kweentso, i-Lupus Nephritis)
• Izifo zesibindi (oko kukuthi isifo soTywala, i-Acute hepatitis, i-Nonalcoholic Fatty Liver Disease, i-Nonalcoholic Steatohepatitis, i-Cirrhosis)
• Izifo eziLungile (okt Asthma, Fibrosis)
• I-Metabolic and Vascular Disease (ie Atherosclerosis, Hypertension, Stroke, Isifo sikashukela)
• I-neurodegeneration (okt i-Alzheimer's, i-Parkinson, i-Huntington kunye ne-ALS)
• Ubuhlungu (oko kukuthi i-Neuropathy)
• Izifo zesikhumba (okt Psoriasis, UVB / Sun Protection)
• I-Toxin Exposure (Arsenic, Asbestos, Cadmium, i-Fluoride, i-Glyphosate, i-Mercury, i-Sepsis, i-smoke)
• Umbono (oko kukuthi ukukhanya okuKhanya, ukuKhathazeka, iiCataracts, iCorneal Dystrophy)

Ukucatshulwa kwe-Nrf2 kunokugqithisa:

• Atherosclerosis
• I-Cancer (oko kukuthi ubuchopho, isisu, intloko, i-neck Pancreatic, iprostate, intsholongwane, i-Thyroid)
• Isifo Sengqondo Esiphefumulayo Sempendulo (CIRS)
• Ukufakelwa kwenhliziyo (ngelixa i-NRF2 evulekile ingaba yingozi, i-NRF2 inokukunceda ukulungisa)
• hepatitis C
• I-Nephritis (iimeko ezinzima)
• Vitiligo

Ngaphaya koko, i-NRF2 inokunceda ekwenzeni izongezo ezithile zesondlo, iziyobisi, kunye nomsebenzi wamayeza. Izixhobo ezininzi zendalo zinokunceda ukubangela i-NRF2. Ngophando lwangoku lophando, abaphandi babonakalisile ukuba inani elikhulu leekhompawundi ekwakukholelwa ukuba zii-antioxidants zazizezinyani ngokwenene. Kungenxa yokuba phantse zonke zifuna i-NRF2 ukuze isebenze, nokuba zincedisa njenge-curcumin kunye neoyile yeentlanzi. I-cocoa, umzekelo, ibonakalisiwe ukuvelisa iziphumo ze-antioxidant kwiimpuku ezine-NRF2 gene.

Iindlela zokuqalisa i-NRF2

Kwimeko yezifo ezingenayo i-neurodeergenerative njenge-Alzheimer's disease, isifo sika-Parkinson, isifo okanye isifo se-autoimmune, mhlawumbi kungcono ukuba ne-Nrf2 iphakanyiswe, kodwa ngeendlela ezivuthayo. Ukuxuba i-activators ye-NRF2 ingaba nesiphumo esongezelelweyo okanye isistim, njengokuba ngezinye izihlandlo sinokuxhomekeka kwimizi. Izindlela eziphezulu zokunyusa iNrf2 ibonakaliso zidweliswe ngezantsi:

• I-HIST (Ukuzivocavoca) + CoQ10 + Ilanga (le synergize kakuhle)
• I-Broccoli ihluma + i-LLLT entlokweni nasemathambo
• Butyrate + Super Coffee + Morning Sun
• Ukwenziwa kwe-Acupuncture (le ndlela yindlela enye, i-laser acupuncture ingasetyenziswa kwakhona)
• Ukuzila
• Cannabidiol (CBD)
• I-Lion's Mane + i-Melatonin
• I-Alpha-lipoic acid + DIM
• Umhlonyane
• Ukuqaliswa kwe-PPAR-gamma

Uluhlu olulandelayo olupheleleyo oluqulethe ezinye iindlela ze-350 zokuqalisa i-Nrf2 ngokutya, indlela yokuphila kunye nezixhobo, iiprobitics, izongezo, iifrimbi kunye namafutha, ama-hormone kunye ne-neurotransmitters, izidakamizwa / imichiza kunye neekhemikhali, iindlela kunye neendlela zokubhala, kunye nezinye iindlela isikhokelo esifutshane malunga noko kunokubangela iNrf2. Ngenxa yokukhawuleza kweli nqaku, siye sishiya ngaphezu kwe-500 nezinye ukutya, izongezelelo zondlo kunye nezixhobo ezinokunceda ukuvula iNrf2. Ezi zilandelayo zidweliswe ngezantsi:

Ukutya:

• Acai Berries
• Utywala (iwayini elibomvu lungcono, ngakumbi ukuba kukho ikhoksi kuyo, njengokuba iprotocatechuic aldehyde kwi-coorks inokuphinda isebenze i-NRF2. Ngokuqhelekileyo, utywala alunyanzelwanga, nangona ukunyusa okuninzi kukunyusa i-NRF2. Ukutya okungapheliyo kunokunciphisa i-NRF2.
• Algae (kelp)
• IiApile
• Ihoyi emnyama
• Nutshontsho zaseBrazil
• I-Broccoli Ihluma (kunye nezinye i-isothiocyanates, i-sulforaphane kwakunye nemifuno e-cruciferous efana ne-bok choy ene-D3T)
• I-Blueberries (0.6-10 g / imini)
• Iidroth (falcarinone)
• I-Cayenne Pepper (iCapsaicin)
• I-Celery (i-Butylphthalide)
• Chaga (Betulin)
• I-Chamomile Tea
• Chia
• Potato yaseTshayina
• Chokeberries (Aronia)
• Icoleta (Ubumnyama okanye iCocoa)
• Cinnamon
• Ikhofi (njenge-chlorogenic acid, iCafestol neKahweol)
• Cordyceps
• Intlanzi (kunye neShellfish)
• I-Flaxseed
• Garlic
• Ghee (mhlawumbi)
• I-Ginger (neKaramonin)
• Gojiberries
• I-Grapefruit (Naringenin - 50 mg / kg / d naringenin)
• Amagilebhisi
• Iti eluhlaza
• guava
• Intliziyo yePalm
• Hijiki / Wakame
• I-honeycomb
• ikiwi
• Imifuno
• I-Lion's Mane
• Mahuwa
• Mangos (Mangiferin)
• Mangosteen
• Ubisi (ibhokhwe, inkomo - ngokusebenzisa umgaqo we-microbiome)
• I-Mulberries
• Ioli yeOlive (ipomace - hydroxytyrosol kunye ne-Oleanolic acid)
• I-Omega 6 Fatty Acids (i-Lipoxin A4)
• Osange Oranges (Morin)
• Amashroom Oyster
• Ipapaya
• Amanqatha
• IiPigeon Peas
• Igromegranate (iPunicalagin, iAlilagic Acid)
• IPolisi (iPinocembrin)
• AmaPatates aMnandi
• IRambutan (iGeraniin)
• Anyanisi
• Reishi
• Rhodiola Rosea (Salidroside)
• I-Bran Bran (i-cycloartenyl ferulate)
• Riceberry
• IRooibos Tea
• IRosemary
• umba-
• Umgcini
• I-Sesame yeOyile
• I-Soy (kunye neeoflavones, Daidzein, Genistein)
• I-squash
• Ierberberries
• I-Tartary buckwheat
• Thyme
• iitumato
• Ubhontshisi be Tonka
• nethamarikhi
• Wasabi
• Ujodo

Indlela yokuphila kunye namadivayisi:

• Ukwenziwa kwe-Acupuncture kunye ne-Electroacupuncture (nge-collagen i-ECM)
• Isibane esiluhlaza
• Imidlalo yeBongo (yandisa i-NRF2 kwi-hippocampus)
• Ukukhawulwa kweCaloric
• Ubunzima (imvula, i-plunges, ibhanti ye-ice, igesi, i-cryotheraphy)
• EMFs (i-frequency ephantsi, njenge-PEMF)
• Ukuzivocavoca umzimba (Ukuzivocavoca okunamandla njenge-HIST okanye i-HIIT kubonakala kuluncedo ekuphembeleleni i-NRF2, ngelixa umthambo omde ungayenzi i-NRF2, kodwa inyusa amanqanaba e-glutathione)
• Ukutya okuphezulu okutya (ukutya)
• Ukushisa okuphakamileyo (iSauna)
• Hydrogen Inhalation kunye ne-Hydrogen Water
• Unyango lwe-Oxygen Hyperbaric
• Utyholongwane olwenziwe kakubi (njengoJovvv)
• Intravenous Vitamin C
• Isidlo seKetogenic
• Ozone
• Ukubhema (akunyanzelwanga - ukwanda kokutshaya kwe-NRF2, ukutshaya okungapheliyo kunciphisa i-NRF2. Ukuba ukhetha ukutshaya, i-Holy Basil inokukunceda ukukhusela ukuhlaselwa kwe-NRF2)
• Ilanga (UVB kunye ne-Infrared)

Probiotics:

• Bacillus subtilis (fmbJ)
• I-Clostridium butyricum (MIYAIRI 588)
• Lactobacillus brevis
• I-Lactobacillus casei (i-SC4 ne-114001)
• Lactobacillus collinoides
• I-Lactobacillus gasseri (OLL2809, L13-Ia, kunye neSBT2055)
• I-Lactobacillus helveticus (NS8)
• I-Lactobacillus paracasei (NTU 101)
• I-Lactobacillus plantarum (C88, CAI6, FC225, SC4)
• I-Lactobacillus rhamnosus (GG)

Izibonelelo, iiHerbs, namafutha:

• I-Acetyl-L-Carnitine (ALCAR) neCarnitine
• Allicin
• I-Alpha-lipoic acid
• Amentoflavone
• Andrographis paniculata
• Agmatine
• Apigenin
• Arginine
• I-Artichoke (i-Cyanropicrin)
• Ashwaganda
• Astragalus
• Bacopa
• Beefsteak (Isogemaketone)
• Berberine
• I-Beta-caryophyllene
• UBidiens Pilosa
• I-Black Cumin Imbewu ye-Oil (Thymoquinone)
• Boswellia
• Butein
• Bhoxisa
• Cannabidiol (CBD)
• I-Carotenioids (njenge-Beta-carotene [i-synergy ne-Lycopene – 2 � 15 mg/d lycopene], i-Fucoxanthin, i-Zeaxanthin, i-Astaxanthin, ne-Lutein)
• Chitrak
• Chlorella
• Chlorophyll
• Chrysanthemum zawadskii
• Cinnamomea
• Common Sundew
• ubhedu
• ECoptis
• CoQ10
• Curcumin
• Damiana
• UDan Shen / uSage obomvu (iMiltirone)
• DIM
• Dioscin
• Dong Ling Cao
• I-Dong Quai (i-female ginseng)
• Ecklonia Cava
• EGCG
• Elecampane / Inula
• Eucommia Bark
• Feric acid Acid
• Fisetin
• Ioyile yeentlanzi (i-DHA / i-EPA-3 1 g / d yeoyile yentlanzi ene-1098 mg EPA kunye ne-549 mg DHA)
• Galangal
• Gastrodin (Tian Ma)
• Gentiana
• IGeranium
• UGinkgo Biloba (Gink gold B)
• Glasswort
• Gotu Kola
• Imbewu yeMbewu yeMbewu
• Agrimony enoboya
• Haritaki (Triphala)
• Hawthorn
• Helichrysum
• IHenna (iJuglone)
• Hibiscus
• Higenamine
• I-Basil engcwele / iTulsi (i-Ursolic Acid)
• Hops
• I-Horny Goat Weed (Icariin / Icariside)
• Indigo Naturalis
• Intsimbi (ayikhuthazwa ngaphandle kokuba ibalulekile)
• I3C
• Iinyembezi zikaYobhi
• UMoringa Oleifera (njengoKafferol)
• Inchinkoto (i-combo yeZhi Zi kunye ne-Wormwood)
• I-Kudzu Root
• Rootice Root
• I-Lindera Root
• I-Luteolin (amanani aphezulu ekusebenziseni, amanani aphantsi awanqanda i-NRF2 kumhlaza nangona kunjalo)
• Magnolia
• Manjistha
• Maximowiczianum (i-Acerogenin A)
• Arnica waseMexico
• Ingxube Yamanzi
• MitoQ
• Mu Xiang
• Mucuna Pruriens
• Nicotinamide kunye neNAD +
• Panax Ginseng
• I-Passionflower (njenge-Chrysin, kodwa i-chyrisin inganciphisa iNRF2 nge-dysregulation ye-PI3K / Akt ukubonisa)
• I-Pau dcoarco (Lapacho)
• Phloretin
• Piceatannol
• PQQ
• Procyanidin
• Pterostilbene
• Pueraria
• I-Quercetin (amanani aphezulu kuphela, amanani aphantsi awanqanda i-NRF2)
• Qiang Huo
• Red Clover
• I-Resveratrol (i-Piceid kunye nezinye i-phytoestrogens ngokwenene, i-Knotweed)
• Rose Hips
• Rosewood
• Rutin
• Sappanwood
• Sarsaparilla
• Saururus chinensis
• I-SC-E1 (iGypsum, Jasmine, i-Licorice, iKudzu, kunye neBhalon Flower)
• Schisandra
• UkuPhilisa (i-prunella)
• Skullcap (Baicalin noWogonin)
• Inkunzi yeSerrel
• Si Wu Tang
• Sideritis
• ISpikenard (Aralia)
• Spirulina
• ISt John's Wort
• ISulfrafa
• Sutherlandia
• Tao Hong Si Wu
• Taurine
• Iindudumo zikaThixo iVine (i-Triptolide)
• I-Tocopherols (njenge-Vitamin E okanye i-Linalool)
• Tribulus R
• Tu Si Zi
• TUDCA
• I-Vitamin A (nangona ezinye i-retinoids zivimbela i-NRF2)
• I-Vitamin C (idosi ephezulu kuphela, idosi ephantsi iyanqanda�NRF2)
• I-Vitex / Umthi ococekileyo
• I-White Peony (i-Paeoniflorin esuka ePaeonia lactiflora)
• Umhlonyane (Hispidulin noArtemisinin)
• Xiao Yao Wan (I-Free and Easy Wanderer)
• Yerba Santa (uEliodictyol)
• Yuan Zhi (Tenuigenin)
• I-Zi Cao (iya kunciphisa i-NRF2 emdlalweni)
• Izinki
• Ziziphus Jujube

IiHormones kunye namaNeurotransmitters:

• Adiponectin
• Adropin
• I-Estrogen (kodwa inganciphisa i-NRF2 kwiisisu zebele)
• Melatonin
• Progesterone
• I-Quinolinic Acid (ekuphenduleni ukukhusela i-excitotoxicity)
• Serotonin
• IiHormone zeTyroid ezifana ne-T3 (inokwandisa i-NRF2 kwiiseli ezinempilo, kodwa iyancipha ngomhlaza)
• Vitamin D

Iziyobisi / iMichiza kunye neekhemikhali:

• Acetaminophen
• Acetazolamide
• Amlodipine
• I-Auranofin
• Bardoxolone methyl (BARD)
• Benznidazole
• bha
• CDDO-imidazolide
• I-Ceftriaxone (kunye ne-beta-lactam antibiotics)
• Cialis
• Dexamethasone
• IDiprivan (Propofol)
• UEliodictyol
• Exendin-4
• Ezetimibe
• Fluoride
• Fumarate
• HNE (oxidized)
• Idazoxan
• I-arsenic engaqhelekanga kunye ne-sodium arsenite
• I-JQ1 (inokuvimbela i-NRF2 kwakhona, engaziwa)
• Governmentiris
• UMelphalan
• Methazolamide
• I-Methylene Blue
• Nifedipine
• NSAID
• Oltipraz
• Ii-PPIs (njenge-Omeprazole kunye neLansoprazole)
• Iiprotandim - iziphumo ezinkulu kwi vivo, kodwa zibuthathaka / azikhoyo ekusebenziseni i-NRF2 kubantu
• Probucol
• Rapamycin
• Reserpine
• IRuthhenium
• Sitaxentan
• Izitatimende (ezifana ne-Lipitor neSimvastatin)
• Tamoxifen
• Tang Luo Ning
• tBHQ
• I-Tecfidera (i-Dimethyl fumarate)
• I-THC (engaqiniseki njenge-CBD)
• Theophylline
• Umbelliferone
• Ursodeoxycholic Acid (UDCA)
• IVerapamil
• Viagra
• 4-Acetoxyphenol

Iindlela / Izinto zokuTshintshe:

• ?7 NAChR isebenze
• AMPK
• Bilirubin
• CDK20
• CKIP-1
• CYP2E1
• EAATs
• Gankyrin
• Gremlin
• GJA1
• H-ferritin ferroxidase
• I-HDAC inhibitors (njenge-valproic acid kunye ne-TSA, kodwa ingabangela ukungazinzi kwe-NRF2)
• Iiprotheni ezithusayo
• IL-17
• IL-22
• IKlotho
• mvumele-7 (uyakhonkca phantsi i-BX1 RNA)
• MAPK
• Abamkeleki bakaMichael (abaninzi)
• miR-141
• miR-153
• i-miR-155 (idibanisa i-MBach1 RNA kwakhona)
• i-miR-7 (ebuchosheni, inceda umdlavuza kunye ne-schizophrenia)
• Notch1
• Uxinzelelo lwe-Oxyidative (njengeROS, RNS, H2O2) kunye ne-Electrophiles
• I-PGC-1?
• I-PKC-delta
• I-PPAR-gamma (iziphumo zentsebenziswano)
• I-Sigma-1 receptor inhibition
• I-SIRT1 (yandisa i-NRF2 ebuchosheni nasemiphungeni kodwa inganciphisa yonke)
• SIRT2
• ISIRT6 (kwisibindi kunye nengqondo)
• SRXN1
• I-TrxR1 inhibition (ukucinywa okanye ukuchithwa kwakhona)
• Zinc protoporphyrin
• 4-HHE

Okunye:

• Ankaflavin
• Asbestos
• Avicins
• Bacillus amyloliquefaciens (esetyenziswe kwezolimo)
• ICarbon Monoxide
• Daphnetin
• Ukuncipha kweGlutathione (ukuncipha kwe80%�90% kunokwenzeka)
• Gymnaster koraiensis
• hepatitis C
• Herpes (HSV)
• Umthi womlotha waseNdiya
• Indigowoad Root
• Isosalipurposide
• Isorhamentin
• I-Monascin
• I-Omaveloxolone (eqinile, aka RTA-408)
• PDTC
• Ukwehla kweSelenium (ukusilela kwe-selenium kunokunyusa iNRF2)
• Luberia waseLiberia
• Sophoraflavanone G
• Tadehagi triquetrum
• Ukubona sinensis (7-DGD)
• ICilongo Flower
• 63171 kunye ne63179 (eqinile)

I-nyukliya ye-erythroid i-2 ehambelana ne-2 indlela yokubonisa, eyaziwa ngokuba ngu-Nrf2, yinto ebhaliweyo eyenza indima enkulu yokulawula iindlela zokukhusela i-antioxidant body body, ngokukodwa ukwenzela ukulawula uxinzelelo lwe-oxidative. Nangona amazinga okwandisa uxinzelelo lwe-oxidative angasebenzisa i-Nrf2, iimpembelelo zalo ziphakanyiswa ngokugqithiseleyo ngokufumaneka kwamacandelo athile. Ukutya okunye kunye nezongezelelo kukunceda kusebenze iNrf2 emzimbeni womntu, kubandakanywa isothiocyanate sulforaphane zivela kwi-broccoli. UDkt Alex Jimenez DC, i-CCST Insight

I-Sulforaphane kunye neZiphumo zayo kuMhlaza, ukusweleka, ukuGuga, uBongo kunye nokuziphatha, isifo sentliziyo kunye nokunye

I-Isothiocyanates zizinye zezona zibalulekileyo zityalo zezityalo onokuzifumana kwisondlo sakho. Kule vidiyo ndiyenzela iimeko ezinzulu kunazo zonke eziye zenziwa. Ukufutshane okufutshane? Dlulela kwisihloko ozithandayo ngokuchofoza enye yeengongoma zangezantsi. Umgca wexesha eliphantsi.

Amacandelo aphambili:

• 00: 01: 14 - I-cancer kunye nokufa
• 00: 19: 04 - Ukuguga
• 00: 26: 30 - Ubunono nokuziphatha
• I-00: I-38: 06 - I-recap yokugqibela
• 00: 40: 27 - Dose

Umgca wexesha elipheleleyo

• 00: 00: 34 - Ukuqaliswa kwe-sulforaphane, ingqwalasela ephambili yevidiyo.
• I-00: I-01: 14 - Ukusetyenziswa kwemifuno yeCruciferous kunye nokunciphisa kuzo zonke izizathu zokufa.
• I-00: 02: 12 - Umngcipheko womhlaza we-prostate.
• I-00: 02: 23 - Ingozi yomhlaza wesibeletho.
• I-00: 02: 34 - Umdlavuza womlenze kwingozi yokubhema.
• 00: 02: 48 - Ingozi yomhlaza wesifuba.
• I-00: 03: 13 - I-Hypothetical: kuthekani ukuba unomdlavuza? (ukungenelela)
• I-00: I-03: 35 - Indlela engabonakaliyo yokuqhuba umhlaza kunye nokufa kwedatha yokudibanisa.
• 00: 04: 38 - Sulforfane nomhlaza.
• I-00: 05: 32 - Ubungqina benkomo obonakalisa impembelelo enamandla ye-broccoli inhluma ehluthwayo ekuphuculweni kwe-tumor kwi-rats.
• I-00: I-06: 06 - Impembelelo yokuxhaswa ngokuthe ngqo kwe-sulforaphane kwizigulane zomhlaza wesibeletho.
• I-00: I-07: 09 - Ukuqokelela i-isothiocyanate i-metabolites kwimizimba yesisu.
• I-00: 08: 32 - Ukuvinjelwa kweeseli zomhlaza zesisu.
• 00: 08: 53 - Isifundo somlando: i-brassicas yasungulwa njengezakhiwo zezempilo nakwiRoma lasendulo.
• I-00: 09: 16 - I-Sulforfane ikhono lokuphucula ukwanda kwe-carcinogen (benzene, acrolein).
• I-00: 09: 51 - NRF2 njengenguqu yokuguqula izakhi nge-antioxidant response elements.
• I-00: 10: 10 - Indlela eyenziwa ngayo i-NRF2 isebenzise ukwanda kwe-carcinogen nge-glutathione-S-conjugates.
• I-00: I-10: I-34 - i-Brussels ihluma iyakhuphula i-glutathione-S-transferase kwaye iyanciphisa umonakalo we-DNA.
• I-00: 11: I-20 - i-Broccoli ihluma isiselo iphakamisa ibhenene ngaphandle kwe-61%.
• I-00: I-13: I-31 - I-Broccoli ihluma i-homogenate ikwandisa i-enzymes e-antioxidant ephezulu.
• I-00: I-15: 45 - Ukusetyenziswa kwemifuno yeCruciferous kunye nokufa kwesifo senhliziyo.
• I-00: I-16: I-55 - i-Broccoli ihluma i-powder iphucula i-lipids yegazi kunye nesifo sengqondo senhliziyo yesifo se-2.
• 00: 19: 04 - Ukuqala kwecandelo lokuguga.
• I-00: I-19: I-21 - I-Sulforaphane-ukutya okunomsoco kwandisa ubomi be-beetles ukusuka kwi-15 ukuya ku-30% (kwiimeko ezithile).
• I-00: 20: 34 - Ukubaluleka kokuvuvuka okuphantsi kwexesha elide.
• I-00: I-22: I-05 - Imifuno e-Cruciferous kunye ne-broccoli ihlumela i-powder ibonakala iyanciphisa iindidi ezahlukahlukeneyo zokumangalisa abantu.
• I-00: 23: 40 - Ukuhlaziywa kwe-mid-video: umdlavuza, izigulane eziguga
• I-00: I-24: I-14 - Iziphumo zemouse zibonisa ukuba i-sulfurephane inokuphucula ukusebenza kwe-immune ngexesha lokuguga.
• I-00: I-25: I-18 -Sulforaphane ithuthukise ukunyuka kweenwele kwimodeli ye-mouse yokukhangela. Umfanekiso kwi-00: 26: 10.
• 00: 26: 30 - Ukuqala kwecandelo lobuchopho kunye nokuziphatha.
• I-00: 27: 18 - Impembelelo ye-broccoli ihluma i-autism.
• 00: 27: 48 - Umphumo we-glucoraphanin kwi-schizophrenia.
• I-00: I-28: 17 - Ukuqala kwengxoxo yokudandatheka (iindlela kunye nezifundo).
• I-00: 31: 21 - Uvavanyo lweMouse usebenzisa i-10 imizekelo eyahlukeneyo yokuxinezeleka okubangelwa uxinzelelo kubonisa ukuba i-sulforaphane efana neyofana ne-fluoxetine (prozac).
• I-00: I-32: I-00 - Ukufundiswa kubonisa ukungena ngokuthe ngqo kwe-glucoraphanin kwiimicebe kusebenza ngokufanayo ekukhuseleni ukudandatheka kwindlela yokuxhatshazwa kwentlalo.
• I-00: I-33: 01 - Ukuqala kwecandelo lokuvelisa i-neurodegeneneration.
• 00: 33: 30 - Sulforaphane kunye nesifo se-Alzheimer.
• 00: 33: 44 - Sulforaphane kunye nesifo sikaParkinson.
• 00: 33: 51 - iSulforaphane nesifo sikaHongtington.
• I-00: 34: I-13 - I-Sulforfane iphakamisa ama-proteins.
• 00: 34: 43 - Ukuqala kwecandelo lokulimala kwengqondo elibuhlungu.
• I-00: I-35: I-01 - I-Sulforaphane injected ngokukhawuleza emva kwe-TBI iphucula imemori (isifundo se mouse).
• I-00: 35: 55 - iSulforaphane kunye ne-plastic neuronal.
• I-00: I-36: I-32 - I-Sulforfane iphucula ukufunda kwi-type II yesifo sikashukela kwiimiceba.
• I-00: 37: 19 - iSulforaphane kunye ne-duchenne i-dystrophy muscular.
• I-00: 37: 44 - I-Myostatin inhibition kwiiseli ze-satellite ze-muscle (in vitro).
• I-00: 38: 06 - Ukuhlaziywa kwexesha elide: i-mortality kunye nomhlaza, umonakalo we-DNA, uxinzelelo lwe-oxidative kunye nokuvuvukala, i-benzene excretion, isifo se-cardiovascular, uhlobo lwesi-2 seswekile, iimpembelelo kwingqondo (ukudandatheka, autism, schizophrenia, neurodegeneration), indlela ye-NRF2.
• I-00: I-40: 27 - Iingcamango zokuqikelela umthamo wamahlumela e-broccoli okanye i-sulforfane.
• I-00: I-41: I-01 - i-Anecdotes xa ihluma ekhaya.
• I-00: 43: 14 - Ekuphekeni kwamaqondo okushisa kunye nomsebenzi we-sulforaphane.
• I-00: 43: 45 - Gut bacteria ukuguqulwa kwe-sulforaphane kwi-glucoraphanin.
• I-00: I-44: I-24 - I-Supplements isebenza ngcono xa idibene ne-myrosinase esebenzayo kwimifuno.
• I-00: I-44: I-56 - Amasu okupheka kunye nemifuno e-cruciferous.
• 00: 46: 06 - Isothiocyanates njenge-goitrogens.

Ngokophando oluninzi lwangoku, inyukliya erythroid 2-enxulumene ne-2 indlela yokubonisa, eyaziwa ngokuba yi-Nrf2, yinto ebalulekileyo ekhutshelweyo eyenza ukuba iiseli zikhusele iindlela zokulwa nokukhusela umzimba womntu kwizinto zangaphandle nangaphakathi kunye nokuthintela ukwanda amanqanaba oxinzelelo lwe-oxidative. Ubungakanani bolwazi lwethu lukhawulelwe kwimicimbi ye-chiropractic kunye nempilo yomqolo. Ukuxoxa ngomxholo, nceda ukhululeke ukubuza uGqirha Jimenez okanye unxibelelane nathi ku915-850-0900 .

Ikhutshwe nguDkt. Alex Jimenez

Ingxoxo yesihloko esongezelelweyo: cBuhlungu obuBuhlungu

Umqolo obuhlunguSesinye sezona zinto zixhaphakileyo zokukhubazeka kunye neentsuku eziphosiweyo emsebenzini kwihlabathi liphela. Iimpawu ezibuhlungu zangasemva kwisizathu sesibini esiqhelekileyo sokutyelelwa kweofisi kagqirha, ngaphezulu kwenani losulelo oluphezulu lokuphefumla. Ngokumalunga neepesenti ezingama-80 zabemi baya kuba neentlungu zentlungu emva kanye ebomini babo. Umqolo sisakhiwo esintsonkothileyo esenziwe ngamathambo, amalungu, iigaments, kunye nezihlunu, phakathi kwezinye izicwili ezithambileyo. Ukwenzakala kunye / okanye iimeko ezixhonyiweyo, ezinje ngedisni, ekugqibeleni inokukhokelela kwiimpawu zentlungu emva. Ukulimala kwezemidlalo okanye ukulimala kwengozi yemoto kudla ngokuba yimbangela eqhelekileyo yeentlungu zangasemva, nangona kunjalo, ngamanye amaxesha ukunyakaza okulula kunokuba neziphumo ezibuhlungu. Ngethamsanqa, ukhetho olulolunye unyango, olufana nokunyamekela kwe-chiropractic, lunokunceda ukunciphisa intlungu emva kokusetyenziswa kohlengahlengiso lomqolo kunye nokunyanzeliswa kwezandla, ekugqibeleni kuphuculwe intlungu. �

I-EXTRA EXTRA | ISIHLOKO ESIBALULEKILEYO: Kunconywe i-El Paso, TX I-Chiropractor

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