IMetabolic Syndrome echaphazela uMzimba | El Paso, TX (2021)

Kwi-podcast yanamhlanje, uDkt Alex Jimenez, umqeqeshi wezempilo uKenna Vaughn, u-Astrid Ornelas, uTruide Torres, kunye ne-biochemist u-Alexander Isaiah Jimenez baxoxe ngesifo se-metabolic syndrome kunye namanyathelo okulungisa.

UGqr. Alex Jimenez DC*:  Kulungile, bafana, size kwenye ipodcast, kwaye samkelekile kuGqr. Jimenez kunye ne-Crew podcast. Wamkelekile, kwaye unosapho apha. Siza kujonga i-metabolic syndrome namhlanje. Isifo seMetabolic sisifo esichaphazela abantu abaninzi. Kwaye okwenzekayo kukuba, ichaphazela enye yabona bantu baninzi abachaphazela i-El Paso, kakhulu kulo mmandla. Kwaye into esinayo ayisosifo, Kulungile? Okokuqala, yindibaniselwano yeenkcazo-ntetho apho oogqirha bezonyango kunye noMbutho wezeMpilo weHlabathi baye bamisela imiba esemngciphekweni omkhulu wokuba sibe ne-stroke, ukuphazamiseka kwezintso, kunye neengxaki zokuphazamiseka kwengqondo. Kodwa iyonke, intle kakhulu ukuba une-metabolic syndrome, uziva ukrummy. Ke namhlanje, into esizakuyenza kukuba siza kuxoxa ngemiba, kwaye singathanda ukuyinikezela kuwe ukuze ibe luncedo kuwe kwaye ulwazi esilunikeziweyo luya kuba luncedo kuwe. wena okanye ilungu losapho. Ke ukuba unalo ithuba kunye nento oyonwabelayo, nceda uye phambili kwaye kwindawo esezantsi. Kukho intsimbi encinci yokubhalisela. Kwaye ibhanti elincinci kwiimarike ukuze ube ngumntu wokuqala ukufumana ulwazi kwixesha elizayo xa sakha sathumela. Kwaye ikuvumela ukuba ubonise okanye usibuze izinto ezibalulekileyo kuwe kwindawo enxulumene nempilo. Ngoku, siza kwenza ntoni namhlanje? Igama lam nguGqr. UAlex Jimenez. Ndinabasebenzi bam bonke apha. Siza kuhamba, kwaye siza kubonisa ngamnye wabo ngamaxesha ahlukeneyo. Kwaye siza kwenza iintshukumo ezinomdla. Siza kuba nesazi sebhayokhemisti esihlala kwiDyunivesithi yeSizwe yeSayensi yezeMpilo, oya kuthi angene ngaphakathi kwaye asinike isiseko sebhayochemistry. Olu lwazi luya kuba luncedo. Siza kuzama ukuyenza ibelula kodwa ibe luncedo kangangoko. Ngoku, khumbula yonke into esiza kuthetha ngayo kwaye namhlanje ijikeleza kwi-metabolic syndrome. I-Metabolic syndrome yinto eyenziwa yimibutho yokunakekelwa kwempilo, kwaye amasebe enhliziyo aneempawu ezintlanu ezinkulu. Ngoku kufuneka ube nezintathu kuzo, ubuncinci ukuze zichazwe njenge-metabolic syndrome. Kulungile, ngoku into yokuqala kukubuza… Uziva njani? Uziva ngathi ukhohlakele, Kulungile? Kwaye ayisiyomvakalelo ilungileyo ukuziva ngale ndlela, kodwa uya kubona ukuba ukuba unazo ezi ntetho, uya kuqaphela ukuba ugqirha wakho unokukunika uxilongo lwe-metabolic syndrome. Ngoku, into yokuqala eyenzekayo udla ngokuba nentwana yamafutha esiswini. Ngoku, esiswini amanqatha abantu abanawo, abantu bayayilinganisa. Kumadoda, sisisu esifana nelonja, isisu esijingayo, kwaye simalunga nokulungileyo, ndingathi, malunga nee-intshi ezingama-40 okanye ngaphezulu kwinkunzi. Kwabasetyhini yi-35 intshi okanye ngaphezulu. Ngoku le yenye yeenkcazo-ntetho zokuqala. Ngoku enye ipresentation luxinzelelo lwegazi oluphezulu. Ngoku uxinezeleko lwegazi abalusebenzisayo li-135 milligrams ngaphezu kwedesilitha. Uxolo, ewe. Miller Mercury yeemilimitha zemercury phezu kwezi nkokeli ukumisela ngokuchanekileyo kwi-diastolic kunye ne-systolic. Ke idiastolic iya kwi systolic izakuba ngu 135, diastolic izakuba ngaphaya kwama 85. Ngoku ayiphindi yenzeke loo nto; uya kuqaphela into. Le ayingoluhlu olugqithisileyo ukusuka ku-OK. I-Metabolic syndrome ine-triglycerides ephezulu. Ngoku i-triglycerides ephezulu iya kuphawulwa egazini. Kulungile, ngoku enye yezinto ezinokumiselwa kwangethuba luxinzelelo lwegazi oluphezulu, olukwanxulunyaniswa nesifo semetabolism. Ke enye yokugqibela kukunyuswa okanye ukuncipha kwe-HDL. HDL okanye amaqhekeza amahle cholesterol. UAlexander uya kuba ngumhlali we-biochemist kwaye athethe nathi ngakumbi malunga naloo nto kwinxalenye yokugqibela yomboniso. Ngoku, khumbula, ndinike izinto ezintlanu a. amanqatha, b. Uxinzelelo lwegazi oluphezulu, c. amanqanaba eswekile yegazi, kunye ne-triglycerides, kunye nokuhla kwee-HDLs. Umbuzo ngowokuba, siza kukwazi njani ukuyilawula le nto ngoku? Ndiza kukunika iindlela ezilungileyo zokwenyani ezisisiseko onokuthi ulawule isifo semetabolism. Ngeli xesha senziwe ngalo namhlanje, sizokwazi ukuvavanya imeko. Kwaye nokuba unayo, ngokusisiseko uya kuba nakho ukuyilawula. Kukho izifo ezinqabileyo onokuthi uphazamiseke. Kwaye kwakhona, esi ayisosifo; yindibaniselwano ye-syndromes okanye iimpawu ezibizwa ngokuba yi-syndrome ngokudibeneyo. Ke i-metabolic syndrome inokuchazwa. Ngoku uya kuqaphela ukuba izinga le-glucose yegazi liya kunyuswa, ngokuqhelekileyo ngaphezu kwe-100; la ngamanani aphakathi kwabantu abanawo. Kodwa ukuba baphezulu kunoko, bayayidala imiba ngoku. Kwakhona, xa unamafutha esiswini 40, kwaye akukho nto ingako, abantu abaninzi banayo. Abantu bakwanazo namazinga eswekile yegazi aphezulu kuno-5.6 kwiglucose yegazi labo i-A1C. La manani kunye ne-150 mg ngedesilitha nganye ye-triglycerides zonke ziqhelekileyo kodwa zidibene. Ngokudibeneyo, ekugqibeleni benza imeko engathandekiyo kwimicimbi yentliziyo. Imicimbi yentliziyo ibonakalisa njengesiphumo. Ke into esiza kuzama ukuyenza kukuzama ukuwisa nokulawula le miba. Ngoku, zeziphi izinto ezinokubangela isifo se-metabolic? Enye yezinto luxinezeleko, ukutshaya, ukuhlala uhleli, kwaneengxaki zokulala neziphazamiso. Singacacisa ngazo zonke kwezi siza kuchaza kabanzi ngazo kwiipodcasts ezizayo. Nangona kunjalo, siza kukwazi ukuxela ngokuthe ngqo okwenzekayo ngendlela engcono. Sikwanayo nemiba yokuvuvukala kunye nokutya okucutshungulwayo. Kweyona nto iphambili ye-metabolic syndrome, eyona nto iphambili yimiba yobuntununtunu kwi-insulin kunye nemiba yoxinzelelo oluphezulu lwegazi, kunye nokudumba. Ke masenze ntoni ukulawula oko? Ndifuna ukuba wazi ukuba yonke le miba mihlanu, nokuba iswekile yegazi, i-triglycerides ephezulu, izibalo eziphantsi ze-HDL, okanye iswekile yegazi, zonke zihambelana nengxaki enye. Bubuntununtunu kwi-insulin. Ubuzaza be-insulin bulawula yonke le miba ukusuka ekunyuseni uxinzelelo lwegazi. Izintso zilawulwa yi-insulin, ebangela ukwanda koxinzelelo lwegazi, kwaye siza kuxubusha loo mbandela kunye nokulungelelaniswa kwayo. Ke ukuba siyakwazi ukulawula iswekile yegazi, ekugqibeleni sineyona ndlela ikhawulezayo neqinisekileyo yokubonelela ngeyona ndlela ikhawulezayo yokuphilisa kunye nokulungisa umntu one-metabolic syndrome. Ke masiqhubele phambili malunga nemiba ezakuba sisiphumo soko. Ngoku, njengoko ndinayo le nto, siza kuqaphela ukuba ixesha elithile uqhubeka nendlela yokuphila enamanqanaba aphezulu ezi zinto zintlanu, uya kuqaphela ukuba uya babe nemingcipheko ephezulu yentliziyo. Ngoku sineqela apha, kwaye ndifuna ukwazisa ngalinye. SinoKenna Vaughn, ongumqeqeshi wethu wezempilo. Umqeqeshi wethu wezempilo ndiyeza ukuba ibe yiyo echaza izigulana zethu ukuba kuqhubeka ntoni. Ndizomngenisa. Sikwanalo nonxibelelwano lwezonyango, oluyiTrudy. UTrudy ngumntu oya kukwazi ukukhupha imibuzo kwaye abone ukuba yeyiphi imiba ekulungeleyo. Ke siza kuthetha ngezinto. Kwaye sinomhleli wethu oyintloko ongumhlali, uAstrid Ornelas, oya kuba nguye ocacisa izifundo ezikuyo. Ukusuka e-Illinois, sikwanaye noAlexander, esinaye ngasemva apho ungamboniyo, kodwa uyabonisa kwaye athi, Molo, Alex, ungabafumana apho? Mholo. Konke kulungile. Ke ulapha phandle, kwaye uza kuxoxa ngemiba kunye necala le-biochemistry yezinto, kwaye sijonge phambili ekuchazeni loo miba. Ngoku, enye yezinto ekufuneka sizenzile kukubuyela kwimiba yokuziva nge-insulin. Uvakalelo lwe-insulin lusisiseko sayo yonke le micimbi. Ke into esiza kuyenza kukuxoxa ngokuthe ngqo ukuba i-insulin inokulawulwa njani. Kodwa oko sikufundileyo kwezi zifundo, kwaye ndiza kungenisa uNkskz. Ornelas, ulapha ukuxoxa ngezifundo malunga nendlela yokulawula iswekile yegazi kunye novakalelo lwegazi.

 

Astrid Ornelas: Kulungile, okokuqala, njengoko usazi, njengoko ukhankanyile, i-metabolic syndrome, yingqokelela yemicimbi yezempilo enokunyusa umngcipheko wokuba nesifo sentliziyo, isifo sohlangothi, kunye nesifo seswekile. Ngokusisiseko ifana, uyazi, inokuchaphazela impilo yethu iyonke kunye nokuphila kakuhle. Kwaye ndenze uphando oluninzi, kwaye ndibafumene kwiZiko leSizwe loLwazi lweBiotechnology, iNCBI. Uphando olwahlukeneyo luchaza ukuba isifo se-metabolic syndrome okanye abantu abane-metabolic syndrome, enye yezona zinto zilula, uyazi, ukucaphula-ukucaphula okulula okanye enye yeendlela ezilungileyo ezinokuthi zisetyenziswe ukunceda ... Buyisela? Ewe, ukunceda ukubuyisela okanye ukubuyisela umva yonke i-syndrome ye-metabolic iya kuba ngokutya kwe-ketogenic. Ke ukutya kwe-ketogenic okanye ukutya kwe-keto yi-carbohydrate ephantsi, ukutya okunamafutha aphezulu, okuthi, ngokwezifundo zophando, kubonelele ngezibonelelo ezininzi kubantu abane-metabolic syndrome. Inokukunceda ukuphucula okanye ukukhuthaza ukunciphisa umzimba, kwaye kunokunceda ukunciphisa isifo seswekile.

 

UGqr. Alex Jimenez DC*: Uyazi, ndifuna ukukhankanya apho, andifumananga nto ngokukhawuleza ukunciphisa i-glucose yegazi kunye nokubuyisela imiba ye-triglycerides kunye nemiba ye-HDL kunokutya kwe-ketogenic. Ke, eneneni, ukuba ufuna ukuyenza ngokukhawuleza, iyamangalisa isantya apho ibuyisela umzimba kwinto oyiyo. Yintoni enye ekhoyo?

 

Astrid Ornelas: Ewe. Ke, njengomzimba womntu, ngokuqhelekileyo, sisebenzisa iswekile okanye iswekile. Ifanele ukuba ngowona mthombo wethu uphambili wamandla, owona mthombo wethu wamandla. Kodwa ke, kubantu abane-metabolic syndrome, abantu abatyebe kakhulu, ukunganyangeki kwe-insulin, isifo seswekile, okanye ukonyuka komngcipheko wesifo seswekile. Ukutya kwe ketogenic kunokuba luncedo kakhulu kuba kukutya okunekhabhohayidrethi ephantsi, iicarbohydrates zijika zibe yiswekile okanye iswekile, kwaye asiyifuni loo nto. Njengaye ukuba abantu bane-metabolic syndrome, bayazi, isifo seswekile kunye nokumelana ne-insulin. Awufuni iswekile emzimbeni wakho kuba ivelisa kakhulu. Baneswekile eninzi kakhulu egazini. Kwaye ngokunyusa ubude bakho, ngokunyusa inani lamafutha owatyayo, kunye nokunciphisa inani le-carbohydrates, ugcina inani eliphantsi. Ugcina i-insulin iphantsi, kwaye wena, ngokutya amanqatha amaninzi, eyona nto ubuya kuyenza kukwenza umzimba ungene kwimeko ye-ketosis.

 

UGqr. Alex Jimenez DC*: Uyakwazo oko? Makhe ndikubuze into. Ndiza ukondla oku ngoku kwi-Kenna, kwaye ndiza kubuza uKenna kumava akho kunye nemiba yeswekile yegazi. Kwenzeka njani ukuba siqulethe kwaye sifunde ukukwazi ukulawula iswekile yegazi lomntu? Ukukhawuleza ngowona ukhawulezayo. Yintoni oyenzayo malunga nokuqeqesha abantu ngabanye, ukubanceda?

 

Kenna Vaughn: Ukuqeqesha abantu ngabanye. Ndihlala ndivavanya ukutya kwabo, kwaye eyona nto iphambili ndithanda ukugxila kuyo yimfundo kuba abantu abaninzi abafundanga malunga, njengoko u-Astrid wayesitsho, i-carbs kunye nendlela abafaka ngayo umzimba wakho. I-Big Mac inokuba ne-54 carbs, kunye nebhatata inokuba ne-30 carbs, kwaye abantu abaqondi ukuba bahluke, kwaye babona amanqaku angama-20 okanye into enjalo. Kodwa indlela i-carbohydrate ehla ngayo emzimbeni inkulu kakhulu. Yiyo loo nto ukutya kwe-ketogenic kusebenza kakuhle kuba usebenzisa ezo carbs zilungileyo eziya kuba neprotheyini ngokunjalo. Kwaye ke kuya kunceda ukuyophula kade xa ithelekiswa neBig Mac, eya kuthi inyuse i-insulin yakho.

 

UGqr. Alex Jimenez DC*: Kwaye yeyiphi indawo yeBig Mac eyona nto inyusa iswekile? Ndiya kuthetha, malunga naloo nto?

 

Kenna Vaughn:  Kunene. Ke isonka, iikhabhu ezikwisonka, ziqhekeka ngokwahlukileyo emzimbeni wakho kunebhatata. Kwaye yiloo nto eza kukunika elo nqanaba liphezulu leglucose. Kwaye emva koko, uya kuba nokuwa kwezinga leglucose, nto leyo iswekile yakho esegazini inyuka inyuka ayiziva imnandi. Ngoko yinto ofuna ukuyiphepha.

 

UGqr. Alex Jimenez DC*: Ndinombuzo kuwe. Yeswekile. Xa ubuza iintlobo zeeswekile onazo, ukhankanye nje ukuba iindidi zecarbohydrates zibalulekile. Ewe. Ndixelele kancinane ngaloo nto.

 

Kenna Vaughn: Umgangatho, njengoko benditshilo, iibhatata, iiavokhado, izinto ezinjalo. Baza kuba neecarbohydrates ezingcono kuwe, oko kuthetha ukuba uya kuziqhekeza ngokwahlukileyo kunokuba ubuya kwenza. Iiswekile ezikhawulezayo njenge-sucrose kunye nezinto ezinjalo.

 

UGqr. Alex Jimenez DC*: Iiswekile ezilula ziphumile, ngokusisiseko, yiyo loo nto, okokuqala, i-metabolic syndrome yayingekho kwangaphambi kokufika kokutya okusulungekisiweyo. Ke iiswekile ezisulungekileyo ziye zabangela le ngxaki. Ke into esifuna ukuyenza iswekile ikhokelela ekudumbeni. Iswekile ikhokelela kwimiba ye-triglyceride. Imiba yeswekile okanye i-insulin sensitivity zizinto ezisisiseko sale nkqubo. Zonke iindlela zikhokelela kubuntununtunu be-insulin kule nkqubo. Kwaye ilungu elisinika i-insulin, elona xabiso libalulekileyo yi-pancreas. Udakada alupheli. Kwaye kuxhomekeke kwindlela i-pancreas esabela ngayo kule drama yeswekile yegazi, imisela ikamva lomntu ngamnye. Iya kutshintsha i-triglycerides. Iya kuguqula uxinzelelo lwegazi ngokubamba ngokuthe ngqo isodiyam kwizintso, izintso umzimba uzilungiselela. Igcina i-sodium, kwaye ngokobume besodium, uxinzelelo lwegazi luyenyuka. Ngoko indlela ekhawulezayo yokunciphisa uxinzelelo lwegazi kukutya kwe-ketogenic. Kwaye oku kuyamangalisa kuba kulula. Ayintsokothanga kangako. Sinokugqithisa. Kwaye ndiyazi ukuba i-Astrid yayinoxwebhu olubalaseleyo lophando kuloo nto. Ndixelele kancinci ngento oyiqapheleyo.

 

Astrid Ornelas: Ewe, eyona nto yayithethwa nguKenna. Ngaphambili, abantu abaninzi bebengawazi umahluko phakathi kohlobo lwekhabhohayidrethi abafuna ukuyitya, njengomzekelo, njengoko ubutshilo, uyazi, abantu abaninzi baya kudla i-Big Mac, kwaye baya kuyitya le bhatata. , kwaye abawazi umahluko phakathi kwecarbohydrate elungileyo; ngokusisiseko, sifuna ukutya into oyibiza ngokuba ziicarbohydrates ezintsonkothileyo, oku kufana nokuba sifuna ukutya njengengqolowa epheleleyo okanye sifuna ukutya okufana nesitatshi esilungileyo ngenxa yokuba abo balapho baqhekeza emzimbeni bawaphule abe yiglucose, abe yiswekile. Kodwa zisetyenziswa ngokucothayo ukuya kwindawo engayi kuzo. Umzimba awuyi kuzisebenzisa ngokuthe ngqo. Kwaye ke uyakufumana oko kuntlitheka, loo nto yeswekile.

 

UGqr. Alex Jimenez DC*: Ngenxa ye-insulin spike, akunjalo? Ilawula i-insulin spike. Uyakwazo oko? Ndifuna ukuzisa i-biochemist yethu yokuhlala apha. Kulungile, ke i-biochemist yethu ekrelekrele nguAlexander. Uneprezenteyishini apha, eneneni, ukuba ndiyakwazi ukuyibona phaya kwaye ndibone ukuba ndiyavela na apha. Nanko ke. Alex, ungasixelela kancinci malunga nento ozama ukuyichaza apha kwicala le-biochemistry yezinto?

 

Alexander Isaya: Njengoko nitshilo, ngokubanzi, i-glucose ngowona mthombo wamandla ophambili ngendlela esiwusebenzisa ngayo ukuwohloka. Ukuqhekeka kwayo ekusebenziseni amandla kubizwa ngokuba yi-glycolysis. Ngoko ngaphandle kokungena kakhulu kuyo, injongo yethu yokugqibela apha yi-pyruvate, ethi ke ingene kumjikelezo we-citric acid ukuze iguqulwe ibe yi-acetylcholine. Kwiimeko eziqhelekileyo, oku kulungile ukuba ube nesidlo se-carbohydrate, kodwa xa ugqithise, ngaba uvelisa i-acetylcholine eninzi? Isetyenziswa nini i-acetylcholine eninzi? Ugqiba ekubeni wenze i-fatty acid synthesis, eyenziwa ngamanqanaba abalulekileyo e-insulin. Ngoko ngokwenza njalo, une-acetylcholine, egqiba ukujika ibe yi-palmitate. Kwaye enye into eyakhankanywa nguKenna kukuba ayikuko konke ukutya okusemgangathweni. Ke apha, sinokubona zonke iintlobo ezahlukeneyo zeasidi ezinamafutha. Ke ngaphandle kokungena kakhulu kwi-biochemistry, kodwa ukukunika nje umbono wokuba kuqhubeka ntoni apha? La manani kwicala lasekhohlo amele inani lekhabhoni emgceni, kwaye amanani ngasekunene kwesemikholoni linani leebhondi eziphindwe kabini. Kwaye ngokuqhelekileyo, iibhondi eziphindwe kabini azidlali indima ebalulekileyo de ungene kwi-digestion kunye nendlela umzimba ozisebenzisa ngayo ezi. Ke ngokuba neebhondi eziphindwe kabini, kumanzi ngakumbi. Ngoko uyawuphawula umahluko phakathi kweqhekeza leoli yehagu kunye neoli yomnquma. Yintoni umahluko? Ukwahlukana kuphela linani lekhabhoni kunye nenani leebhondi ezimbini. Ke apha sineasidi ye-oleic, ioli yomnquma, kwaye ke sinamafutha ahluthayo. Siyabona ukuba umehluko uvelele kwinani lekhabhoni kunye neebhondi ezimbini. Iibhondi eziphindwe kabini zivumela indawo ephantsi yokunyibilika. Yiyo loo nto ioyile yomnquma ilulwelo olukwiqondo lobushushu begumbi xa ithelekiswa ne-fatty acids, kwaye oku kudlala indima ebalulekileyo kwindlela umzimba ozisebenzisa ngayo ezi ntlobo zezinto.

 

UGqr. Alex Jimenez DC*: Alex, utsho njalo? Sonke siyazi ukuba umsebenzi ogqwesileyo weoli yeoli, ioyile yeeavokhado, kunye neoyile yekhokhonathi yeyona nto ilungileyo, kungenxa yoko le nto isenzeka.

 

Alexander Isaya: Ngokuchanekileyo. Ngoko ke xa benabo iibhondi eziphindwe kabini, kokukhona kuya kuba kumanzi ngakumbi emzimbeni kwaye kuvumele umzimba ukuba usebenzise loo mafutha ngexesha ngokuchasene nokuvala imithambo yemithambo kunye nokudala amacwecwe ngaphakathi kwaloo mithambo.

 

UGqr. Alex Jimenez DC*: Egqwesileyo. Uyakwazo oko? Enye yezinto ezenziwa yi-insulin, ipakisha iicarbohydrates kumandla akwiseli. Ukuba wenza oko, kwenzeka ntoni ngale swekile yegazi? Ekugqibeleni, i-insulin iyayikhupha kwaye iyifake kwiiseli. Ekugqibeleni, iseli iyakhula, kungoko isisu sityeba. Ekugqibeleni, isisu siqala luhlaza kwaye sizuze iiseli ezinamafutha, kwaye ziqala ukuba zikhulu, zibe zikhulu, zibe zikhulu ngenxa yokuba zitofwa apho. Loo nto iqala ukuphumela ngaphandle, kwaye xa ingasakwazi ukungena, iphelela kwiindawo ezifana nepancreas. Iphelela kwiindawo ezifana nesibindi. Iphela kwi-intramuscular kwi-tissue ye-muscular. Yiyo loo nto sinengqokelela. Kwaye xa unesisu esikhulu, yiloo nto iingcebiso kugqirha, kungekhona kuphela nge-triglycerides kumanqanaba eglucose yegazi kodwa kunye namafutha esisu. Kwaye yenye yezinto ekufuneka sizivavanye. Ke ezi ngoku ezi fatty acids? Zeziphi iiasidi ezinamafutha asetyenziselwa, ngokuqhelekileyo, uAlexander?

 

Alexander Isaya: Iiasidi ezinamafutha zisetyenziswa phantse kuyo yonke into engaphakathi emzimbeni, ngakumbi ukusetyenziswa kwamandla. Kufana nokuthi, ungakhetha ukukwazi ukuhamba imayile ezintlanu okanye iimayile ezili-10? Uhlala ufuna ukuhamba iimayile ezili-10, akunjalo? Ke igram yamafutha egram njengomthombo wamandla inamandla ngakumbi kune-glucose okanye i-carbs. Ke iicarbs zibonelela ngeegremu zethu ezine zeekhalori ezine kwigram nganye kwaye amafutha ajikeleze alithoba. Ngoko ke iphantse yangaphezulu kokuphindwe kabini kumthamo wamandla owuvelisayo kwezi asidi ezinamafutha. Inxalenye ekhohlisayo kukwazi nje ukuba zeziphi ezilungileyo. Ngoko ke ukungena kwi-fatty acids emihle, eya kuba yibo kunye neebhondi ezimbini. Ngoko ke ndiyathetha, naziphi na ioli yezityalo, amafutha ezilwanyana, kuxhomekeke kwiziphi na, sivame ukufuna ukuhlala kude nenani elikhulu le-ionic acid engafanelekanga, njengoko idla ngokubangela iimpendulo zokuvuvukala ngendlela yokuvuvukala. Kodwa ezinye zezi zilungile, ngakumbi i-EPA kunye ne-DHEA. Ngoko i-DHEA isetyenziswa ngaphakathi kwenkqubo ye-nervous. Ijikwe yaba yi-neurotic acid kunye ne-EPA ngokunjalo. Ke ukufumana ezi oyile zaselwandle ziya kulungele inkqubo yakho nje ngokubanzi.

 

UGqr. Alex Jimenez DC*: Uyazi ukuba yintoni, njengoko ndiqonda ezi nkqubo kwaye ndiqala ukuqonda i-biochemistry emva kwayo, ukuyizisa ekhaya kule nkqubo phantsi kwecandelo leselula elihloniphayo. Ibonisa ukuxabisa malunga nento eyenza i-fatty acid excess. Ngoku kwakhona, kwenzeka ntoni ngenxa yokuninzi kwezi asidi ezinamafutha okanye iicarbohydrates egazini? Umzimba uzama ukuyigcina. Izama ukugcina ikwimo yamanqatha, ize ityhalelwe kwi-pancreas. Ngoko ufumana la mafutha ngaphakathi kwi-pancreas. Ukuba ayinakuyenza apho, ekugqibeleni iyibeka esibindini. Kwaye njengoko besitshilo, iyifumana esiswini, okanye kuxa siyibona njengento yokugqibela. Ngoko ke ndiyathanda ukuthatha ingcaciso kwaye ndaphule enye inqaku, icandelo loxinzelelo lwegazi oluphezulu. I-insulin inefuthe elithe ngqo kwizintso. I-insulin ixelela izintso, Jonga, kufuneka sipakishe ezi zinto kumanqatha. Kwaye ngaphandle kokudlula kakhulu kwi-chemistry dynamics, unokubona ukuba into eza kwenzeka kukuba izintso ziya kuyalelwa ukuba zibambe i-sodium eninzi. Kwikhemistri, i-biochemistry, kunye nesayensi yezonyango, sifunde ukuba okukhona ugcina isodiyam, uxinzelelo lwegazi luyenyuka. Ngokwenyani, nantso indlela olukhawuleza ngayo uxinzelelo lwegazi. Ke ukwenza oko kangangexesha elithile, kwaye emva koko unyanzelise ukuqokelelwa kwee-atherosclerotic plaques kuba loo mafutha akhona, kwaye ayinakuhamba naphi na. Uzakuba nengxaki kwixesha elide, kwixesha elizayo. Ke xa sithetha ngeeoyile, njengoko uAleksandire esandula ukwenza, enye yezinto esizibuzayo kukuba, Kulungile, zeziphi iioyile esingenako ukuzazi? Sisebenzisa ioli yecanola, ioli yombona, ioyile yembewu yeesame. Ndiyazithanda iimbewu zesesame. Kodwa ingxaki kukuba ioli yembewu yesesame ibangela ukuvuvukala, njengoko watshoyo uAlex, nge-arachidonic acid. Ke into ekufuneka siyenze kukufumanisa ngokuchanekileyo ukuba zeziphi iintlobo zeoyile esinokuthi sizenze kunye neeavokhado, njengoko uKenna ebetshilo, ngumthombo omkhulu wamafutha esinokuwusebenzisa kwaye senze izinto zicutshungulwe ngakumbi. Imizimba yethu kunye nephiramidi endala yokutya imbi kakhulu kuba inzima kwiicarbohydrates. Ke enye yezinto esizijongayo kukugcina onke loo macandelo. Ngoko sathetha nge-triglycerides, amafutha esisu, ukuba adityaniswa njani. Kwaye nganye kwezi, ndifuna ukuyikhomba le kwakhona. Uxinzelelo lwegazi oluphezulu, oluyi-135 uxinzelelo lwegazi oluphezulu, aluqwalaselwa kwi-135. Ngokuqhelekileyo, yi-140. Kulungile. Ke ukuba kunjalo, kutheni sisebenzisa i-triglycerides kwi-150 ayithathwa njengento egqithisileyo. Uyazi, i-HDL ingaphantsi kwama-50 ayijongwa njengeyoyikekayo, kodwa ngokudibeneyo, ukuba unayo yonke into, ezi zintathu zezi zixhobo zintlanu. Yiloo nto ekhokelela kwindawo yokugula kunye nokuziva utyumke, singasathethi ke ngalo naliphi na ixesha elide loku kuya kukhokelela kukuphazamiseka kwemetabolism, iingxaki zentliziyo, iingxaki ze-stroke, ukuphambana okwenzekayo ngenxa ye-metabolic syndrome ethatha ixesha elide. zingaphakathi komntu. Ndifuna ukubuza uAlexander. Unezinto ezishukumisayo ezinomdla, njengoko ndifuna ukubonisa ngoku, kwaye siza kubonisa isikrini sakhe kanye apha kuba unamalungu anomdla kwinto echaphazela isifo semetabolism.

 

Alexander Isaya: Ke uhlobo lokungena kwinto eyiyo, ndiyaqikelela ketosis, kuba wonke umntu uyazibuza ukuba kuqhubeka ntoni. Ndiye ndafumana lo mzobo apha ndinizobele nina. Asiyihoyi indlela ye-ephedrine apha, kodwa nje ngokubanzi. Ke into ezakwenzeka kuqala kukuba uza kuphelisa nayiphi na i-glucose onayo. Ngoko ke, umzimba ugcina malunga ne-100 grams yeglucose esibindini kunye neegram ezingama-400 ngaphakathi kwenxalenye yezihlunu zomzimba wonke. Ke ukuba uphinda-phinda 500 amaxesha, loo nto malunga 2000 calories, leyo ngumda yakho yemihla ngemihla, ngoko ke une phantse imini yonke ixabiso glucose esoloko igcinwe ngaphakathi emzimbeni wakho. Kodwa xa sele uyigqibile loo nto, umzimba wakho uya kuqala ukukhangela ezinye izinto. Okwangoku, kuthatha iintsuku ezimbalwa ukuba umzimba wakho utshintshe kwiswekile evuthayo, eyiglucose, ukuya ekutshisweni kwemizimba yeketone kumafutha. Ke kuzokwenzeka ntoni? Okokuqala, i-adrenals yakho iya kuqalisa ukukhulula i-epinephrine, i-precursors, i-norepinephrine. Kwaye oku kungenxa yezinto ezimbalwa ezahlukeneyo. Uza kufumana i-jittery encinci kuqala, kwaye uya kuziva kakubi kwiintsuku ezimbalwa zokuqala, kodwa emva koko umzimba wakho kwaye uqalise ukutshintsha njengoko ingqondo yakho iqala ukuqalisa ukusebenzisa le mizimba ye-ketone njengomthombo wamandla. Ke njengokuba usenza i-norepinephrine, ezi zifana nje, lo ngumphezulu weseli apha. Ezi ziziphawuli nje ezandulelayo ezahlukeneyo. Ke sine B1, B2, B3, kunye ne A2. Ukwenza oku kuya kuphawula kunye nomqondiso kwiprotheni yegesi, eya kuvumela i-aminoglycosides ukuba isebenze i-ATP kwi-cyclic AMP. Ngoku, i-cyclic AMP yinxalenye ebalulekileyo yokuthotywa kwe-fatty acids. Inxalenye epholileyo kukuba ithintelwe yi-phosphodiesterase. Ngoko xa abantu beza bathi, kutheni i-caffeine isitshisi esilungileyo samafutha? Esona sizathu sibalulekileyo kukuba i-caffeine inhibits phosphodiesterase kwinqanaba elithile. Awufuni ukuphambana kakhulu nge-caffeine kwaye uqale ukwenza iikomityi ezininzi zekofu.

 

UGqr. Alex Jimenez DC*: Ingaba kufuneka ndifumane iiglasi ezisibhozo zekofu, okanye zingaphi iikomityi zekofu?

 

Alexander Isaya: Ndicinga ukuba iglasi enye yekofu ingaphezulu kokwaneleyo. Ke ngokuba ne-cyclic amp isebenze ngakumbi, uvula into ebizwa ngokuba yiprotein kinase A, eyenza i-ATP isebenze, emva koko iqale isiseko sobomi esine-hormone. Nje ukuba i-hormone-sensitive lipase isebenze, iqala ukuthotywa. Iqala ukuqhekeza iiasidi ezinamafutha. Nje ukuba la ma-acids anamafutha angenile kwaye aphulwe, angena kwi-mitochondria, kwaye i-mitochondria iya kuvelisa ubushushu kule nto. Yiyo loo nto abantu be-ketosis behlala beshushu ngokwenene. Ngoko ke ndicebisa ntoni xa abantu beqala ukwenza ukutya kwe-ketosis? Amanzi? Ukutya kwe-Keto, ngokuqinisekileyo amanzi kwaye ngokunjalo, ndingathi, L-carnitine. Ke njengoko sijonge kwi-L-carnitine apha, sinokubona ukuba ngexesha lokuthotywa kwe-asidi enamafutha, usebenzisa i-L-carnitine njengothutho oluphambili phakathi kwenwebu ye-mitochondrial yangaphandle kunye nenwebu yangaphakathi ye-mitochondrial. Ke ngokusebenzisa i-fatty acids, nantsi i-asceloca enamafutha; emva kokuba siye saphula ezi fatty acids, iya kungena CPT enye, leyo carnitine, itywina translocated ufuna okanye poly transferase enye. Iza kungena kunye nokusebenzisana ne-carnitine, kwaye emva koko iya kujika ibe yi-seal carnitine. Emva kokuba i-carnitine itywinwe iguqukela kuyo, inokungena kwi-membrane ye-mitochondrial yangaphakathi ngokusebenzisa ezi zimbini ze-enzymes translocation kunye ne-CPT ezimbini ukuba ziphulwe kwakhona kwikhowudi yesitywina, eyenza i-byproduct efanayo ne-glucose ekugqibeleni. Kwakhona, ke, i-mitochondria yakho inokusebenzisa ezi kwi-beta-oxidation. Into enye oyaziyo kukuba kufuneka usele amanzi amaninzi kuba abantu abahamba nge-ketosis baya kuba belawula umjikelo we-urea. Ngoko kufuneka uqinisekise ukuba utsala amanzi amaninzi okanye usele amanzi amaninzi imini yonke. Nabani na owenza i-keto diet namhlanje unobuncinci be-gallon yamanzi imini yonke, kungekhona yonke kanye, kodwa yonke imini.

 

UGqr. Alex Jimenez DC*: Kuyamangalisa, Alex, ukuba uyibeke kunye kuba iyavakala kum kwaye ichaza ukuba kutheni abantu besithi xa sibabeka kukutya kwe-ketogenic, bayanyusa ubushushu bomzimba kwaye amanzi akunceda ukuba ugcine yonke inkqubo. ukupompa kuba yile nto senziwe ngayo. Kwaye kwakhona, iindlela ozibonise i-hydrogen emanzini ziyimfuneko ukuze inkqubo yenzeke.

 

Alexander Isaya: Ewe. Imiba ethile phakathi kwezi zinto zivuselela enye kwenye; Yindlela edibeneyo yonke. Kodwa uya kuwulawula umjikelo we-urea ngexesha le-ketosis kakhulu kunaxa ungekho. Umzekelo, wonke umntu owaziwayo okanye iikati zaziwa ngokuba nevumba lomchamo obolileyo. Kwaye kufuneka sijonge oko kwisizathu sokuba kutheni kunjalo? Ngoko ke ngokubanzi ebantwini apho, umxholo we-urea kumchamo ziipesenti ezintathu. Kwiikati, kwelinye icala, naphi na phakathi kwesithandathu ukuya kwisithoba ekhulwini. Ngoko kufuneka ucinge ngayo. Sesiphi ekuphela kwesilwanyana esanyisayo emhlabeni esisisilwanyana esitya inyama kuphela? Kuba batya inyama kuphela, usapho lweenkazana lulawula urea lwazo kwibhayisekile, ngaloo ndlela lube ne-urea eninzi kumchamo wabo. Ngoko ukuba ungumntu otya inyama kuphela, uya kuba ne-urea eninzi. Ke ngoko kufuneka usele amanzi amaninzi ukuze uwagungxule kwizintso zakho.

 

UGqr. Alex Jimenez DC*: Iyamangalisa loo nto kuba icacisa isizathu sokuba siqiniseke ukuba wonke umntu usela amanzi amaninzi, aze ke azive engcono. Kwaye ndiyaqikelela ukuba asiyijongi ngokuchanekileyo, ukuba asiyenzi kakuhle, sifumana into ebizwa ngokuba ngumkhuhlane we-ketogenic, akunjalo? Kwaye ke umzimba uziva uhlobo lwe-crummy de ubuyisele kwaye uzinzise iswekile yegazi ngee-ketones. Ngoku, umzimba unokusebenzisa iiketoni kwiswekile, njengoko kusaziwa njalo. Ke enye yezinto esizenzayo kukufundisa abantu kanye indlela yokuqhuba inkqubo. Kwaye ndiyazi ukuba sinamanqaku ophando apha, kwaye i-Astrid ifuna ukuxoxa kancinci ngaloo nto.

 

Astrid Ornelas: Ke ngokusisiseko, njengoko u-Alex etshilo, xa abantu beqala ukuhamba, baqala ukulandela ukutya kwe-ketogenic, siyafuna, uyazi, njengoko watshoyo, sifuna ukuqiniseka ukuba bahlala benamanzi, kodwa ngaphezulu koko. Ndicinga ukuba enye into esifuna ukufundisa abantu kuyo kukuba abantu abaninzi abaziyo, uyazi, kufuneka sigcine umzimba ngamafutha amahle ukuze njengoko umzimba uhlengahlengisa, uqalise ukutshisa amanqatha njengamafutha kuneswekile okanye iswekile. Ke sifuna ukufundisa abantu, ngawaphi amanqatha amahle esifuna ukuba bawathande ukuwatya, uyazi, kuba, njengoko, kufuneka sigcine kula mafutha anokuthi umzimba ungene kwi-ketosis kwaye sinokuhamba ngayo yonke. inkqubo echazwa nguAlex.

 

UGqr. Alex Jimenez DC*: Uyakwazo oko? Ndingathanda ukuzisa uTrudy apha kuba nguye onxibelelana nezigulana okwangoku. Siyavavanya umntu ukuba une-metabolic syndrome. Ngokubhekiselele kwizibonelelo, uhamba njani kwinkqubo yokunikezela? Molo, Trudy. Trudy, siza kwenza ntoni apho? Ndizakubuza, uyizisa njani lonto? Kuba ingumnxibelelanisi wethu wezonyango, unxibelelwano lwethu lwempilo, kwaye nguye oya kuthi ngokusisiseko asinike ulwazi olunceda isigulana kwicala elifanelekileyo.

 

Trudy Torres: Ewe, molo. Kwaye mna, uyazi, olu lulo lonke ulwazi olugqwesileyo, olumangalisayo ukuba sinokulunika uluntu. Kwaye ndiyazi ukuba oku kunokuba nzima kakhulu kubantu abangenalo olu lwazi. Kulapho ke ndingena khona xa abantu besiza, uyazi, mhlawumbi bayasitsalela umnxeba okanye bangene bebuza ngeempawu zabo ezahlukeneyo. Abayazi ngokuqinisekileyo ukuba bafumana isifo se-metabolic syndrome. Kodwa uyazi, enye yezinto ezibaxhalabisayo kukuba bayavuka. Ngokusekwe kwiinkxalabo zabo, ndibanxibelelanisa kwiprayimari yethu noKenna, kwaye baya phambili bathi, kulungile, ke, ngawaphi amanyathelo ekufuneka siwathathe kwaye uKenna ngokuqinisekileyo abafundise ukuza kuthi ga ngoku, kulungile, le yilebhu. umsebenzi oza kufuneka uwuthathe. Sibadibanisa noDkt Jimenez emva kokuba sazi kakuhle inkxalabo yabo ephambili, kwaye siza kuqala ukukhupha izinto njenge-anyanisi ukuze sifike emazantsi ezinto kwaye sibenze bazive ngcono. Abayi kuhamba kuphela neziphumo ezithile, kodwa baya kuhamba nabo, njengoko u-Astrid wathi, ngawaphi amanqatha alungileyo onokuba nawo? Ndifanele nditye ntoni? Ke baya kuhamba benolwazi oluninzi, kodwa kunye nesakhiwo. Enye into esiyinikezelayo kukuba uKenna uhlala ekhona, uyazi, ukuphendula nayiphi na imibuzo kunye noGqr. Jimenez, ngoko akufuneki bazive becinezelekile ngenkqubo njengoko behamba ngcono. , ubomi obusempilweni.

 

UGqr. Alex Jimenez DC*: Uyazi, ukuba enye yezinto kukho ukubhideka okuninzi phaya, kwaye kufuneka ndinyaniseke kuni. Kukho ulwazi oluninzi olungelulo phaya. Olu lwazi lungachanekanga lunokuhlelwa ngokwenjongo okanye oludala, okanye alukho ngoku, kunye nezi zinto zintlanu kunye nomntu onazo ezintathu. Kubalulekile ukuphinda ngokuchanekileyo indlela yokulungisa lo mbandela kunye nomntu kwaye utshintshe ubomi babo kuba akukho nto ikhawulezayo ukutshintsha umzimba kunokutya kwe-ketogenic. Kufuneka kwakhona sibabeke esweni abantu ngabanye kwaye sibabeke esweni ngale nkqubo. Ngoku sinoKenna Vaughn oneendlela esizisebenzisayo eofisini kwaye ziluncedo kuye. Oogqirha benza oku kwilizwe liphela, kodwa kuluncedo ekuncedeni ukukhokela kunye nokuvumela ukusebenzisana kunye nonxibelelwano phakathi kwethu, ababoneleli, kunye nesigulana. Zeziphi izinto esizinikayo, Kenna?

 

Kenna Vaughn: Sinoqeqesho lomntu omnye, olulunge kakhulu xa usaqala into. Njengoko babethetha ngokutya kwe-ketogenic. Usenokubhideka, kwaye kukho ulwazi olungachananga. Ke ngoku kuqeqeshwa komntu nomntu, kulungile kuba sinokunxibelelana ngosetyenziso esinalo, kwaye ukhuphe ifowuni yakho. Ungathumela umyalezo obhaliweyo okhawulezayo; hey, ndabona enye iwebhusayithi isithi ndingatya oku, kodwa enye yathi, le, ndingayifumana le? Izinto ezinjalo. Singakucacisa oko kubhideka ngokukhawuleza, okunokukugcina usendleleni kunokwenza loo mdlalo wokuqikelela. Sikwanazo nezikali eziqhagamshela kule app, nto leyo esivumela ukuba sijonge ubunzima bamanzi abanawo kunye namafutha abanawo. Kwaye sinokubeka esweni umsebenzi wabo nge-wristband ukuze silandelele rhoqo amanyathelo abawathathayo. Qinisekisa ukuba benza umthambo kuba imithambo ikwaluncedo kakhulu ekuncedeni ukuthoba iqondo leswekile yegazi.

 

UGqr. Alex Jimenez DC*: Uyazi, ukhankanye malunga nokubeka iliso. Senza loo nto eofisini apho sithumela abaguli ekhaya kunye nezikali zokwenyani eziyi-BIAs ezincinci kunye nezandla zabo kunye nesandla. Sinokwenza okuninzi kakhulu kwizigulana ezifuna ukunxibelelana neofisi yethu. Sinokulufumana ngokuthe ngqo ulwazi olukhutshelweyo, kwaye sinokubona ii-BIA zabo zitshintsha. Sikwasebenzisa inkqubo engaphakathi emzimbeni, apho senza uhlalutyo olunzulu lwesiseko sesiseko se-metabolic rate, kunye nezinye izinto esixoxe ngazo ngepodcast yangaphambili. Oku kusivumela ukuba sidibanise indlela enokulinganiswa yokuvavanya indlela umzimba oguquka ngayo kunye nokubuyisela ngokukhawuleza umzimba ukuya okanye kude kwisiqendu se-metabolic syndrome. Yimvakalelo engakhululekanga kakhulu enokuyenza. Akukho nto itshabalalisa umzimba kolu luhlu lwemiba ngexesha elinye. Nangona kunjalo, kulula ukubona ukuba umzimba wenza yonke into ngokukhawuleza. Ilungisa ukutya kwe-ketogenic, isusa ubunzima bomzimba, inciphisa amanqatha esibindi, inciphisa amafutha e-intramuscular, ibuyisela iswekile yegazi. Iyenza ingqondo isebenze ngcono. Iyazinceda ii-HDL ngezifundo ezithile, kwaye ndiyazi ukuba i-Astrid iyazi ukuba kukho uphononongo phaya olutsalela ulwazi malunga nokuba i-HDL inyuswa njani kunye kunye nokutya kwe-ketogenic. Sinesifundo apha. Ungayibeka kwiscreen kanye apho ndicinga ukuba ufumene ebonisa ii-HDLs. Ngaba ndilungile? Kwaye i-apolipoprotein, inxalenye ye-lipid ye-HDL, nayo iyaphakanyiswa kwaye isebenze icandelo lemfuzo. Ndixelele ngaloo nto.

 

Astrid Ornelas: Ke ngokusisiseko into eninzi yabaphandi, uninzi lweengcali zokhathalelo lwempilo phaya, oogqirha, bahlala besithi, kukuba xa abantu bene-cholesterol ephezulu, uyazi, kwaye sihlala sithetha nge-cholesterol embi. Ngokwamanqaku amaninzi ophando, ngokuqhelekileyo kudityaniswa nemfuza xa bene-cholesterol embi okanye iqhekeza le-LDL. Ukuba abazali bakho, ukuba utatomkhulu nomakhulu wakho bane-cholesterol ephezulu, kukwakho umngcipheko owonyukileyo wokuba ube nemfuza yokuba sele une-cholesterol ephezulu kunye nokongeza oko njengokutya kwakho. Kwaye ukuba ulandela indlela yokuphila yokuhlala kwaye uyazi ukuba awuwenzi ngokwaneleyo umthambo okanye ukuzivocavoca umzimba, unomngcipheko owongezelelweyo wokuba ne-cholesterol embi.

 

UGqr. Alex Jimenez DC*: Uyazi, ndiza kutsala ulwazi ukusuka ndiye ndaqaphela ukuba Alexander ukutsala into ulwazi phezulu apha kwesikrini. Ubonisa imonitha apho unokubona i-glucose yakhe yegazi kunye nezikrini aqhubekela phambili nazo kwaye ambeke apho phezulu. Nako usiya. Alex, khawutsho ukuba uthetha ngantoni kanye apho ngoba ndiyabona ukuba uthetha nge apolipoprotein, i-lipoprotein, kunye ne-HDL fragments apho.

 

Alexander Isaya: Ngoko uhlobo lokungena kancinci kuyo yonke into apha. Ke kwenzeka ntoni xa utya into eza kubangela ukwanda kwe-cholesterol? Ngoko kuqala kuzo zonke, unazo ezi zofuzo ebizwa Callum microns ngaphakathi kwilumen yamathumbu okanye iphecana yakho GI, kwaye babe apolipoprotein B 48. Bane B 48 kuba 48 ekhulwini apolipoprotein B 100, ngoko ke umahluko nje kancinci eyahlukileyo. Ezi microns ziya kuzisa ezi zinto emzimbeni kwaye zizigqithisele kwii-capillaries zisebenzisa i-apolipoprotein C kunye ne-apolipoprotein E. Nje ukuba zingene kwii-capillaries, ziya kuthotywa kwaye zivumele imiba eyahlukeneyo yomzimba ukuba zizisebenzise. Ngoko ke ndinethishu ezintathu. Sinezicubu ze-adipose, izicubu zentliziyo, kunye nezihlunu zamathambo. Ngoko izicubu zentliziyo zine-KM ephantsi, kwaye izicubu ze-adipose zine-KM ephezulu. Ke yintoni i-KM? I-KM ngumlinganiselo nje wendlela ezisetyenziswa ngayo ii-enzymes. Ngoko i-KM ephantsi ithetha ukucaciswa okuphezulu kokuzibophelela kula ma-acids anamafutha, kwaye i-Km ephakamileyo ithetha ukucaciswa okuphantsi kubo. Ngoko ke ngawaphi amalungu mathathu omzimba? Basebenzisa amandla amaninzi. Yingqondo, intliziyo kunye nezintso. Ezo zezona nxalenye ze-caloric zokusetyenziswa komzimba ukuze uhlale uphila. Ke, okokuqala, intliziyo ixhomekeke kwizixa ezikhulu kula mafutha acids apha, kwaye ukuwadlulisela entliziyweni kusebenzisa uninzi lweeasidi ezinamafutha. Ndicinga ukuba malunga nama-80 ekhulwini; Ama-70 ukuya kuma-80 ekhulwini amafutha ayo aphuma kwiiasidi ezinamafutha. Kwaye ukuhambisa ezi, umzimba wakho usebenzisa ezi Callum microns. Ke nje ukuba i-Calum microns iphume kwii-capillaries, sele iyi-LDL. Inokhetho olubini: i-LDL, Inokubuyiselwa esibindini okanye inokutshintsha iziqulatho zayo nge-HDL, kwaye izitywina zinokuzisa ngokuchanekileyo kwiindawo ezifanelekileyo. Yiyo loo nto i-HDL ibaluleke kakhulu kuba bahambisa kwiindawo ezifanelekileyo ukuba ezi zi-Callum microns okanye ezi LDLs azithunyelwanga ngokuchanekileyo esibindini. Ngoko kutheni iLDL iyingozi kangaka kwinkqubo yomzimba wethu? Nazi izizathu ezimbalwa zokuba kutheni. Ngoko njengoko i-LDL igqobhoza kuwo wonke umzimba, ibonwa njengento yasemzini ngamacrophage ethu, yaye iimacrophage zethu ziiseli zethu ezisetyenziselwa ukusabela komzimba. Ngoko i<em>macrophages ekugqibeleni igquba ezi LDLs, yaye zijika zibe zezi zinto zibizwa ngokuba ziiseli zogwebu. Iiseli ze-foam ekugqibeleni ziba yi-atherosclerotic plaque. Kodwa into abayenzayo kukuba bazibethelele ngaphakathi okanye phantsi komphezulu we-epithelial lining, ebangela ukwakheka kwezi seli zogwebu apha kwaye ekugqibeleni bavale iindlela, kubangele i-plaque. Ke ngokutya amanqatha angcono, ukuba ne-HDL ephezulu, unokuwaphepha la matye kwaye uphephe iiplagi ze-atherosclerotic, ezivala imithambo yakho.

 

UGqr. Alex Jimenez DC*: Uyazi ukuba yintoni, eneneni, ikhonkco phakathi kwe-atherosclerotic plaques kunye nesifo se-metabolic olenzile kakhulu, ngokucacileyo ngoku, kwaye sisizathu sokuba iimeko ezinde ze-metabolic syndrome zidale ezi ngxaki. Ndifuna ukuthatha umzuzwana ndibulele bonke abasebenzi balapha kuba into esiyenzayo kuzisa ulwazi oluninzi kunye namaqela amaninzi. Kwaye ukuba umntu unomcimbi, ndifuna adibane nobuso azobubona xa engena eofisini. Ke, Trudy, baxelele indlela esibabulisa ngayo kunye nento esiyenzayo ngabo xa bengena ukuba bavakalelwa kukuba banokuba lixhoba le-metabolic syndrome.

 

Trudy Torres: Ewe, sisikelelwe kakhulu ngokuba neofisi echulumancisayo nenamandla. Uyakuhlala uziva usekhaya. Ukuba asinayo impendulo echanekileyo ngelo xesha, ngokuqinisekileyo siza kuphanda. Asizukuphosa icala lakho. Sihlala sibuyela kuwe. Wonke umntu uphathwa njengomntu. Uyazi, inqanawa nganye esinayo, yahlukile ngendlela yayo. Ke ngokuqinisekileyo asenzi indlela yokusika icookie. Sihlala siqinisekisa ukuba, njengoko benditshilo, uhamba nolona khetho luxabisekileyo, olunolwazi kuwe. Simane sifowuna kude. Sicofa nje kude. Kwaye, uyazi, ungaze uzive ngathi akukho mbuzo ufanelekileyo. Sihlala sifuna ukuqiniseka ukuba yonke imibuzo kunye nokuxhalabisa uhlala ufumana impendulo engcono kakhulu.

 

UGqr. Alex Jimenez DC*: Guys, ndifuna ukunixelela, enkosi. Kwaye ndifuna ukwabelana nawe ukuba sibe kumaziko amangalisayo xa sisenza; kukho umthambo obandakanya ukubuyisela umzimba kwimeko yesiqhelo. Sisebenza ngaphandle PUSH Fitness Centre. Senza ipodcast kwiziko lokomelela. Kwaye ungalubona ulwazi apha noDanny Alvarado. Kwaye nguye lowo okanye uDaniel Alvarado, umlawuli wePush Fitness esisebenza kunye neqela lezonyango kunye nabanyangi benyama ukukunceda ubuyisele umzimba wakho apho kufuneka ube khona. Sijonge ukubuya, kwaye njengoko benditshilo, ukuba uyabulela, ngaba ufana nale nto sinayo apha, fika ezantsi emazantsi amancinci, cofa iqhosha elincinci, kwaye ucofe ukubhalisa. Kwaye ke qiniseka ukuba uyayibetha intsimbi ukuze ube ngowokuqala ukuva ukuba siqhubeke. Kulungile, enkosi, bafethu, kwaye siyanamkela kwakhona. Kwaye uThixo akusikelele. Yiba mhle.