Contents
intshayelelo
Ulusu kunye namathumbu anonxibelelwano olulodwa. I Inkqubo yamathumbu likhaya leetriliyoni zeemicroorganisms ezinceda ukuguqula i-homeostasis yomzimba ngelixa ugcina inkqubo yomzimba ukusebenza ukuze umzimba usebenze ngokuchanekileyo. Ulusu luneseti yemisebenzi kunye nokuba lelona lungu likhulu kwaye linceda ukukhusela umzimba kwizinto zangaphandle kwingozi. Xa ezi zinto ziphazamisayo ziqala ukuchaphazela amathumbu okanye ulusu, kunokukhokelela kwiimeko ezininzi ezibangela ukuba umzimba ungasebenzi. Xa amathumbu echaphazeleka kwezi zinto ziphazamisayo, kunokubangela ukuphazamiseka kwamathumbu kunye nokudumba, kuchaphazela ulusu kwaye kubangele ukuphazamiseka. Inqaku lanamhlanje liza kuxoxa ngengxaki yolusu eyaziwa ngokuba yi-psoriasis kunye nokuba unxibelelwano lwe-gut-skin luchatshazelwa njani yi-psoriasis. Ukubhekisa izigulana kubaboneleli abaqinisekisiweyo, abanezakhono abaziingcali kunyango lwe-gastroenterology. Sinikezela ngesikhokelo kwizigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo ibalulekile ekubuzeni imibuzo eqondayo kubaboneleli bethu. UDkt Alex Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli
Ngaba i-inshorensi yam ingayihlawula? Ewe, kunokwenzeka. Ukuba akuqinisekanga, nali ikhonkco kubo bonke ababoneleli beinshorensi esibakhuselayo. Ukuba unemibuzo okanye iinkxalabo, nceda ufowunele uDkt Jimenez kwi-915-850-0900.
Yintoni Psoriasis?
Ngaba urhawuzeleleka kakhulu ebusweni nasezingalweni zakho? Ngaba ukutya okuthile kuwenza mandundu umthambo okanye ulusu lwakho? Okanye ngaba ukhe waneengxaki zamathumbu ezichaphazela impilo yakho? Uninzi lwezi mpawu luphawu lwemiba yokukrala echaphazela amathumbu kwaye inyanyaniswa nengxaki yolusu eyaziwa ngokuba yi-psoriasis. Izifundo zophando ziye zachaza i-psoriasis njengesifo esingapheliyo solusu yinkqubo yokuzimela apho ukuhlukana okungaqhelekanga kunye nokunyuka kwe-hyper-proliferation ye-epidermis kwenzeka ngokubomvu kunye nokunyuka. I-Psoriasis ichaphazela malunga ne-2% yabemi ngokubanzi emhlabeni kwaye yinkqubo ye-autoimmune eqhutywa ziiseli ze-T ezisebenza ngokungaqhelekanga. Izifundo ezongezelelweyo zikhankanyiwe ukuba i-psoriasis ixhaswa kukudumba okubangela ukuba ukwanda kwe-keratinocyte kungalawuleki kwaye kunokwahlukana okungasebenziyo. Iindlela zokukrala zenza ukuba i-psoriasis isebenze kwiindawo ezahlukeneyo zomzimba, ibangela ukuba umntu abe lusizi ngenxa yokuba uyarhawuzelela kwaye abe lusizi.
Isishwankathelo sePsoriasis-Ividiyo
Ngaba unamaxolo, amabala anezilonda kwiindawo ezithile zomzimba wakho? Ngaba uziva naziphi na iingxaki zamathumbu ezikuchaphazela rhoqo? Ngaba uziva iziphumo ezivuthayo eziphazamisa amathumbu akho kunye nolusu? Uninzi lwezi meko ziimpawu zokuba ufumana ukuphazamiseka kwamathumbu okunxulunyaniswa nengxaki yolusu eyaziwa ngokuba yipsoriasis. Ividiyo engentla ichaza indlela amathumbu kunye nolusu oluchaphazeleka ngayo ngenxa ye-psoriasis kunye nendlela yokuyiphilisa ngokwemvelo. Uphando lophando lukhankanyile ukuba xa umntu ephethwe yi-psoriasis yesikhumba, kungenxa yokutshintshwa kwe-gut microbiota. Xa umntu ekrwela indawo apho i-psoriasis yakheka khona, inokonakalisa ulusu kwaye ibangele ukuba ibhaktheriya ibe koloni ngelixa ibiza ukudumba ukuba kwenzeke kwindawo echaphazelekayo. Uphando olongezelelweyo lufumene ukuba iziphazamiso zamathumbu ezifana ne-IBD (isifo samathumbu esivuthayo) kunye ne-psoriasis zidibene ngenxa yokwanda kwentsebenziswano ye-receptor pathogens yokuvuvukala ephazamisa iiseli zomzimba zomzimba.
Indlela uQhagamshelwano lweGut-Skin luchatshazelwa ngayo yiPsoriasis
Amathumbu likhaya leetriliyoni zeemicroorganisms ezinceda ukuhlaziya i-homeostasis yomzimba ngelixa ilawula amajoni omzimba. Ekubeni umzimba uhlala kwi-microorganisms kwiindawo ezahlukeneyo, kuquka ulusu kunye namathumbu, inceda ukugcina i-homeostasis. Ulusu lunceda ukukhusela umzimba kwizinto zangaphandle kwaye lunonxibelelwano lwe-bidirectional kunye nenkqubo yamathumbu. Nangona kunjalo, njengayo nayiphi na inkqubo ye-autoimmune, ihlala iqala ngamathumbu. Uphando lophando lukhankanyile ukuba i-psoriasis sisifo solusu esingapheliyo esingena kwiiseli zomzimba zomzimba, ezibangela ukwanda kokuvutha kolusu kunye nokwenza ubomi bomntu bube buhlungu. Ngenkqubo yamathumbu ekwabangelwa ziimpawu zokukrala, abantu abaninzi ababandezelekileyo baya kuba ne-IBD, SIBO, kunye nolunye ukuphazamiseka kwamathumbu okunokuphazamisa umzimba. Ulwazi olongezelelweyo lubonisiwe ukuba utshintsho kwi-microflora kwi-axis ye-gut-skin ukusuka kwimfuza okanye kwizinto ezisingqongileyo kunokufaka isandla kwizifo ezahlukahlukeneyo. Kodwa xa ezi zinto ziqala ukubangela ukwanda kwamanqaku okuvuvukala emzimbeni, kunokuchaphazela umgangatho wobomi bomntu ngemikhwa ebenza babe lusizi.
isiphelo
Umzimba udinga amathumbu kunye nolusu ukugcina i-homeostasis kunye ne-metabolize amajoni omzimba. I-gut microbiota inceda ukuthutha izondlo ezidingwa ngumzimba kwaye zilawule ukhuseleko lomzimba, ngelixa ulusu lukhusela umzimba kwizinto zangaphandle ngelixa lilelona lungu likhulu. Amathumbu kunye nolusu lunonxibelelwano lwe-bi-directional olubavumela ukuba bagcine umzimba ekubandezelekeni kwi-dysbiosis. Xa izinto eziphazamisayo zichaphazela amathumbu okanye ulusu, oko kunokukhokelela kwiziphazamiso ezininzi kwaye kwenze ubomi bomntu bube lusizi. Ulusu luthwaxwa yimeko eyaziwa ngokuba yi-psoriasis, isifo esingapheliyo sokudumba esibangela ukurhawuzelelwa, izilonda ezinamabala ezinokuchaphazela iindawo ezijikeleze umzimba. I-Psoriasis inxulunyaniswa nokuphazamiseka kwamathumbu, njengoko izinto ezininzi ziyenza ibe mandundu amaphawu okudumba kwaye inokuba yinkathazo ukuba ayiphathwa kwangoko. Ukubandakanya utshintsho oluncinci olunceda amathumbu kunye nempilo yolusu lunokunceda ukukhulula umntu kwi-psoriasis kunye nokubuyisela umgangatho wobomi babo.
Ucaphulo
UChen, uLihui, et al. "Ulusu kunye ne-Microbiome ye-Gut kwi-Psoriasis: Ukufumana ukuqonda kwi-Pathophysiology yayo kunye nokuFumana i-Novel Therapeutic Strategy." Imida kwi Microbiology, Frontiers Media SA, 15 Dec. 2020, www.ncbi.nlm.nih.gov/pmc/articles/PMC7769758/.
UDe Francesco, uMaria Antonia, kunye noArnaldo Caruso. "I-Gut Microbiome kwi-Psoriasis kunye ne-Crohn's Disease: Ngaba ukuPhathwa kwayo yiNqununu eqhelekileyo yePathogenesis yabo?" Iigonya, MDPI, 5 Feb. 2022, www.ncbi.nlm.nih.gov/pmc/articles/PMC8877283/.
Ellis, uSamantha R, et al. "Ulusu kunye neGut Microbiome kunye nendima yayo kwiiMeko zeDermatologic eziqhelekileyo." Iintsholongwane, MDPI, 11 Nov. 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6920876/.
UNair, uPragya A, kunye noTalel Badri. "Psoriasis." Ku: StatPearls [Internet]. Isiqithi saseTreasure (FL), iStatPearls Publishing, 6 Epreli 2022, www.ncbi.nlm.nih.gov/books/NBK448194/.
Olejniczak-Staruch, Irmina, et al. "Utshintsho lweLusu kunye neGut Microbiome kwiPsoriasis kunye nePsoriatic Arthritis." I-International Journal ye-Molecular Sciences, MDPI, 13 kuMatshi 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8069836/.
URendon, uAdriana, kunye noKnut Schäkel. "I-Psoriasis Pathogenesis kunye noNyango." I-International Journal ye-Molecular Sciences, MDPI, 23 kuMatshi 2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6471628/.
isikhanyeli
Umgangatho wobuchule wokuSebenza *
Ulwazi olulapha ku "Umdibaniso weGut-Skin On Relieving Psoriasis"Akujoliswanga ukuthatha indawo yobudlelwane obubodwa kunye nomntu oqeqeshiweyo wezempilo okanye ugqirha onelayisensi kwaye akusiyo isiluleko sonyango. Sikhuthaza ukuba wenze izigqibo zezempilo ngokusekelwe kuphando lwakho kunye nentsebenziswano kunye nochwepheshe bezempilo abaqeqeshiweyo.
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Iintsikelelo
UDkt Alex Jimenez D.C., I-MSACP, RN*, I-CCST, IFMCP*, I-CIFM*, I-ATN*
email: qeqeshi@elpasofunctionalmedicine.com
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Ubume obubambeneyo: ILayisensi yeeNkcazo ezininzi: Ugunyaziswe Ukuziqhelanisa I-40 States*
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