Ukugcina iGut Flora Ibhalansi

Kubantu abaneengxaki zesisu, ngaba ukugcina ibhalansi yeflora yamathumbu ikhuthaza kwaye iphucule impilo yamathumbu?

Amathumbu eFlora Balance

Ukugcina ulungelelwaniso lweflora yamathumbu yinxalenye yempilo yokwetyisa. I-Gut microbiota, i-gut microbiome, okanye i-gut flora, zii-microorganisms, ezibandakanya ibhaktheriya, i-archaea, i-fungi, kunye neentsholongwane ezihlala kwi-digestive tract. Uhlobo kunye nobungakanani beebhaktheriya ezikhoyo zixhomekeke kwindawo yazo emzimbeni onokuthi ube ngamathumbu amancinci kunye nekholoni. Le yindlu yokugcina inkunkuma / isitulo, kwaye ikholoni iquka amakhulu eentlobo ezahlukeneyo zebhaktheriya, ezinemisebenzi ethile kunye nemisebenzi.

UFlora ongenampilo

Ezona ntsholongwane zixhaphakileyo ziibhaktheriya ezinokubangela ukugula ukuba ziyekwa zingajongwanga, kubandakanywa iintsholongwane ezifana ne-streptococcus/strep throat okanye i-E. coli/usulelo lomgudu womchamo kunye norhudo. Ezinye iintsholongwane eziqhelekileyo ezifumaneka kwikholoni ziquka: (Elizabeth Thursby, Nathalie Juge. 2017)

I-Clostridioides Difficile

• C. diff overgrowth kunokubangela ilindle elinamanzi elinuka kakubi yonke imihla, kunye nesisu esibuhlungu kunye nokuthamba.

Enterococcus Faecalis

• I-Enterococcus faecalis ngunobangela wosulelo lwesisu lwasemva kotyando kunye nomgudu womchamo.

U-Escherichia Coli

• I-E. coli ngoyena nobangela wesifo sorhudo kubantu abadala.
• Le bhaktiriya ikhona phantse kuwo wonke umntu omdala osempilweni.

UKlebsiella

• I-Klebsiella overgrowth inxulumene nokutya kwaseNtshona okubandakanya inyama eyahlukeneyo kunye nemveliso yezilwanyana.

Bacteroides

• Ukugqithisa kwe-Bacteroide kuhambelana ne-colitis, ebangela ukuvuvukala okubuhlungu kwekholoni.

UFlora osempilweni

Iibhaktheriya ezinempilo ezifana ne-Bifidobacteria kunye neLactobacillus, zinceda ukugcina ibhalansi yeflora yamathumbu kunye nokugcina ibhaktheriya engekho mpilweni. Ngaphandle kweentyatyambo ezisempilweni, ikholoni yonke inokonganyelwa ziintyatyambo ezimbi, ezinokubangela iimpawu ezifana nesifo sohudo kunye/okanye ukugula. (Yu-Jie Zhang, et al., 2015) Ezi ntsholongwane zikhuselayo, zinemikroskopu zinemisebenzi ebalulekileyo equka:

• Ukuncedisa nge-vitamin synthesis - iivithamini B kunye ne-K kumathumbu amancinci.
• Yandisa umsebenzi we-immune system.
• Ukugcina ukuhamba kwamathumbu rhoqo.
• Ukugcina ikholoni ecocekileyo ngokwemvelo ngaphandle kwesidingo sokucoca ikholoni.
• Ukonakalisa iibhaktheriya ezingenampilo.
• Ukuthintela ukukhula kwebhaktheriya engafanelekanga.
• Ukuqhawula amaqamza erhasi ekuvubeleni kokutya.

Ukukhutshwa kweebhaktheriya

Nokuba zibhalwe njengebhaktiriya esempilweni okanye azikho mpilweni, zombini zizinto eziphilayo ezineseli enye ezinokutshatyalaliswa ngokulula. Ngamanye amaxesha, kuyimfuneko, njengaxa kufuneka uthathe i-antibiotics ukubulala usulelo lwe-strep throat. Nangona kunjalo, amayeza okubulala iintsholongwane abulala ibhaktheriya enenzuzo, enokukhokelela kwiingxaki ezidibanisayo ezinokubandakanya: (Mi Young Yoon, Sang Sun Yoon. 2018)

• Ukungahambi kakuhle kwamathumbu - urhudo kunye nokuqunjelwa.
• Ukukhula kweYeast - kunokubangela ukurhawuzelelwa, ukutshisa malunga nomngxuma wokukhupha ilindle kwaye kukhokelela kusulelo lobufazi kunye negwele lomlomo.
• I-Dysbiosis - igama lobugcisa lokungabikho kwebhaktheriya enempilo okanye ukungalingani kwebhaktheriya.
• Iingxaki kubantu abane-irritable bowel syndrome.

Kukho iindlela ezahlukeneyo zokutshabalalisa ibhaktheriya kuquka.

• Abantu abafuna ukuthatha i-antibiotics ukunyanga usulelo. (Eamonn MM Quigley. 2013)
• Ukusetyenziswa okungapheliyo kwe-laxative.
• Ukusetyenziswa ngokugqithisileyo kweFayibha.
• Uhudo oluhlala ixesha elide - lunokukhupha iibhaktheriya ezimbi kunye ezilungileyo.
• istres
• Ukugqibezela i-bowel prep, njengaleyo ifunekayo kwi-colonoscopy.

Ukuxilongwa kweMiba yeFlora yeGut

Amaxesha amaninzi, iingxaki ze-gut flora ziya kuzilungisa ngokwazo, kwaye akukho manyathelo afunekayo. Nangona kunjalo, abantu abajongene neengxaki zamathumbu ezingapheliyo, ezifana ne-colitis okanye isifo sokukrala kwamathumbu, banokufuna ungenelelo lwezonyango lwebhaktheriya yekholoni yabo.

• Uhlalutyo oluBanzi lweSitofu sokuTyeka/CDSA luvavanyo lwesitulo olujonga ukuba loluphi uhlobo kunye nobungakanani bebhaktheriya ekhoyo, amazinga okufunxa izondlo/isantya sokwetyisa, kunye nokuba kugaywa kakuhle kangakanani na ukutya.
• Ukuba kukho umahluko omkhulu kumlinganiselo webhaktiriya engafanelekanga xa ithelekiswa nenzuzo, umboneleli wezempilo unokucebisa ukuba iprobiotic okanye isongezelelo se-microbial ephilayo ukunceda ukubuyisela kunye nokugcina ibhalansi yeflora yamathumbu.

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Ukungasebenzi kakuhle kwamathumbu

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Ucaphulo

Thursby, E., & Juge, N. (2017). Intshayelelo kwi-hut gut microbiota. Ijenali ye-Biochemical, 474 (11), 1823-1836. doi.org/10.1042/BCJ20160510

Zhang, YJ, Li, S., Gan, RY, Zhou, T., Xu, DP, & Li, HB (2015). Iimpembelelo zebhaktheriya yamathumbu kwimpilo yabantu kunye nezifo. Ijenali yamazwe ngamazwe yenzululwazi yeemolekyuli, i-16 (4), i-7493-7519. doi.org/10.3390/ijms16047493

Yoon, YAM, & Yoon, SS (2018). Ukuphazamiseka kwenkqubo yendalo yamathumbu ngama-Antibiotics. Ijenali yezonyango kaYonsei, 59(1), 4–12. doi.org/10.3349/ymj.2018.59.1.4

Quigley EM (2013). Iibhaktheriya zamathumbu kwimpilo kunye nezifo. I-Gastroenterology & hepatology, 9 (9), 560-569.