Ukujongwa kwi-Autonomic Neuropathy kunye ne-Gut Disorders

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Umzimba unemithambo-luvo emininzi edibanayo kwaye iphuma ngaphandle umqolo kwi kwinkqubo yomnatha. Ezi mithambo-luvo zibonelela ngemisebenzi emininzi ekufuneka umzimba usebenze ngokuchanekileyo, ukusuka ekusebenzeni kwemoto ezingalweni, emilenzeni, nasentanyeni ukuya kwimisebenzi yeemvakalelo efana nokuqonda ukuba kungakanani ukukhanya okuza emehlweni, loo mvakalelo yokugcwala emehlweni. inkqubo yamathumbu, naxa kukho into echukumisa ulusu. Umzimba udinga le mithambo-luvo kwimisebenzi yemihla ngemihla kwaye xa umntu esiva intlungu kwiingozi kunye nokulimala. Xa kukho izinto ezenza umonakalo we-nerve okanye imiba yamathumbu echaphazela ngaphakathi emzimbeni, inokubangela iimpawu ezininzi kwaye ibangele ukuba umntu azive edakumbile. Inqaku lanamhlanje lijonga inkqubo ye-nervous parasympathetic, ukuba iyichaphazela njani i-gut microbiota, kunye nendlela i-autonomic neuropathy ephazamisa ngayo inkqubo yamathumbu kubantu abaninzi. Thumela izigulana kubaboneleli abaqinisekisiweyo, abanezakhono ezikhethekileyo kunyango lwamathumbu kubantu abaphethwe yi-autonomic neuropathy. Sikhokela izigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo ibalulekile ekubuzeni imibuzo eqondayo kubaboneleli bethu. UDkt Alex Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli

 

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Yintoni iParasympathetic Nervous System?

 

Ngaba ukhe wahlangabezana nemiba yamathumbu echaphazela umzimba wakho? Kuthekani ngokuziva unesiyezi okanye isiqaqa xa umile? Ngaba kubonakala kunzima ukulungisa amehlo akho ukusuka kubumnyama ukuya ekukhanyeni? Okanye ngaba ukhe wadumba amathumbu? Ezi zibonakaliso kunye neempawu zihlala zichaphazeleka xa i-parasympathetic nerves yonakalisiwe kwaye ibangela imiba yamathumbu emzimbeni. Inkqubo ye-nervous parasympathetic. njengoko uphando luchazile yona, igcina amandla omzimba ukuba asetyenziswe kwixesha elizayo ngelixa ilawula imisebenzi yomzimba. Ezi ngqungquthela zinceda umzimba ukuba ungene "kwimeko yokuphumla" evumela ukuba umzimba usebenze kwindawo engaphantsi koxinzelelo kunenkqubo ye-nervous system enovelwano, eqhuba impendulo "yokulwa okanye indiza". Iintsholongwane ze-parasympathetic nazo zinceda kunye nephecana le-GI, njengoko uphando olongezelelweyo lubonisa inkqubo ye-nervous parasympathetic inceda ukukhupha i-excitatory kunye ne-inhibitory control GI kunye ne-motility emathunjini. Imithambo-luvo yeparasympathetic kunye ne-gut microbiota zidityanisiwe njengoko zinceda ukuphembelela i-homeostasis yomzimba.

 

Ichaphazela njani iGut Microbiota?

Ke ingqondo kunye namathumbu ziqhagamshelwe emzimbeni njengoko zinceda ukuthumela ulwazi emva naphambili ukubonelela nge-homeostasis yomzimba kunye nomsebenzi wokuzikhusela ekuthinteleni izifo. Ke kwinkqubo ye-nervous parasympathetic kunye nendlela eyichaphazela ngayo i-gut microbiota, konke kungenxa ye-vagus nerve egcina i-gut microbiota isebenza kwaye yenza umsebenzi wayo ukuxhasa umzimba. Izifundo zophando zibonisile ukuba i-vagus nerve iyona nxalenye ephambili yenkqubo ye-nervous parasympathetic. I-vagus nerve inceda ngonxibelelwano lwe-bi-directional phakathi kwengqondo kunye nenkqubo yamathumbu ngokubeka esweni imisebenzi ebalulekileyo yomzimba. Eminye yemisebenzi eyenziwa yi-parasympathetic nervous system kwi-gut microbiota ibandakanya:

• Ukulawula imo
• Impendulo yomzimba
• Inqanaba lentliziyo
• Ukugonywa
• Ichaphazela umgaqo we-homeostasis yesisu
• Qhagamshela iindawo zovakalelo kunye nezokuqonda kwengqondo

 

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Isishwankathelo kwiVidiyo yeParasympathetic Nerves

Ukuziva iziphumo ezivuthayo ngaphakathi kwamathumbu akho? Kuthekani ngokuziva unesiyezi ngokuma nje kancinci? Ngaba unengxaki yokutya okanye awukuthandi ukutya? Uninzi lwale miqondiso ye-parasympathetic nerves iyachaphazeleka, ibangela ukungaqhelekanga kwi-gut microbiota. Ividiyo engentla ichaza ukuba yintoni inkqubo ye-nervous parasympathetic eyenzayo kunye nendlela edlala ngayo indima yayo kuwo wonke umzimba. Inkqubo ye-nervous parasympathetic nayo inobambiswano kunye ne-gut microbiota. Uphononongo lophando lukhankanyiwe ukuba intsebenziswano phakathi kwenkqubo ye-nervous parasympathetic kunye ne-gut microbiome iqinisekisa ukugcinwa okufanelekileyo kwe-homeostasis kunye nemisebenzi yokuqonda yomzimba. I-axis ye-gut-brain inceda ukukhuthaza ukusebenza kakuhle komzimba ngelixa iqinisekisa ukuba amalungu e-motor-sensory ayayenza imisebenzi yawo.

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Indlela i-Autonomic Neuropathy ichaphazela ngayo iSistim yeGut

 

Ukulimala okuchaphazela i-gut microbiota kunye nenkqubo ye-nervous parasympathetic kunokubangela ukuvutha kwamathumbu emathunjini kunye nomonakalo we-nerve kwinkqubo ye-nervous. Oku kwaziwa ngokuba yi-autonomic neuropathy, kunye uphando lubonisa ukuba olu hlobo lwe-neuropathy lubangela imiba yomzimba kunye namathumbu afana nesifo sikashukela kunye ne-gastrointestinal motility kwaye igalelo kwezinye iimpawu ze-GI. Olunye uphononongo lophando lufumene ukuba i-autonomic neuropathy inokutshintsha umgaqo we-homeostasis we-gut microbiota. Xa oku kusenzeka, umzimba uya kuqalisa ukuba neempawu ezahlukeneyo ezichaphazela ilungu ngalinye kwaye zibenze bangasebenzi kakuhle. Umzimba uya kuphuhlisa iimpawu ezininzi xa i-gut microbiota ichaphazeleka. Ezi mpawu zibangela ukuhla kwe-vagal outflow okanye ukwanda komsebenzi onovelwano, oya kuhambelana nokuhla kancinci kwe-gastrointestinal motility.

 

isiphelo

Amathumbu kunye neenkqubo ze-nervous zinonxibelelwano lwe-bi-directional olunceda ukubonelela umzimba ngenkxaso efanelekileyo yokuzivikela komzimba kunye ne-metabolizing homeostasis yokusebenza. Iimbilini kwinkqubo ye-nervous zixutywe kwintambo yomgogodla kwaye zinceda ukunika imisebenzi emininzi kwiingalo, izitho, imilenze kunye nezicubu zomzimba. Imithambo-luvo yeparasympathetic kwinkqubo yemithambo-luvo inceda umzimba ukuba uphumle kwaye wetyise izondlo ezinikwa umzimba. Xa imithambo-luvo okanye amathumbu echaphazeleka kumonakalo, kunokubangela iingxaki ezahlukeneyo ezibangela ukungasebenzi kakuhle kwemisebenzi ye-motor-sensory yomzimba. Xa oku kusenzeka, abantu abaninzi banokufumana unyango olwahlukeneyo lokubuyisela imisebenzi yomzimba emathunjini kunye nemithambo-luvo yeparasympathetic kunye nokunciphisa iimpawu eziza nayo.

 

Ucaphulo

Breit, Sigrid, et al. "I-Vagus Nerve njengeModyuli ye-Brain-Gut Axis kwi-Psychiatric and Inflammatory Disorders." Frontiers kwi-Psychiatry, Frontiers Media SA, nge-13 kaMatshi 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5859128/.

Browning, Kirsteen N, kunye noR Alberto Travagli. "Ukulawulwa kweNkqubo yeNervous yeNervous yeGastrointestinal Motility kunye neMfihlo kunye nokuModareyitha kweMisebenzi yeGastrointestinal." IPhysiology eBanzi, Ilayibrari yeSizwe yaseMelika yoNyango, Okthobha 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4858318/.

Kornum, Ditte S, et al. "Uvavanyo lweGastrointestinal Autonomic Dysfunction: Iimbono zangoku kunye nezexesha elizayo." Ijenali yamayeza onyango, MDPI, 31 kuMatshi 2021, www.ncbi.nlm.nih.gov/pmc/articles/PMC8037288/.

Mayer, uEmeran A. “Iimvakalelo zamathumbu: Ibhayoloji esakhulayo yoNxibelelwano lweGut-Brain.” UPhononongo lweNdalo. I-Neuroscience, ILayibrari yeSizwe yezeMithi yase-US, nge-13 Julayi 2011, www.ncbi.nlm.nih.gov/pmc/articles/PMC3845678/.

Tindle, Jacob, kunye noPrasanna Tadi. "I-Neuroanatomy, iParasympathetic Nervous System-Statpearls-NCBI Bookshelf." Ku: StatPearls [Internet]. Isiqithi saseTreasure (FL), StatPearls Publishing, 5 Nov. 2021, www.ncbi.nlm.nih.gov/books/NBK553141/.

Tougas, G. Ijenali yaseKhanada yeGastroenterology = Ijenali Canadien De Gastroenterologie, ILayibrari yeSizwe yaseMelika yoNyango, Mar. 1999, yentshutshiso.ncbi.nlm.nih.gov/10202203/.

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