Iintsuku ezintlanu ngeProLon kwaye uya kubona iziphumo | El Paso, TX.

Inzululwazi yakutshanje iye yavula amandla okuzila ukutya ukuze kulungiswe ukuguga komzimba kunye nokuqhawula izifo ezingapheliyo, umzekelo, ukutyeba ngokugqithiseleyo, isifo seswekile, umhlaza, ukuphazamiseka kwe-autoimmune, isifo se-Alzheimer kunye nesifo senhliziyo. E-El Paso Emva kweklinikhi, UDkt. Jimenez Injongo kukufundisa uluntu malunga neenzuzo zezempilo zokuzila ukudla. Iingcamango ukuzazisa kubo ngendlela ephephile, esebenzayo ngokusebenzisa Ukutya Ukuxilisa Ukutya (IMF).

Ucwaningo lwangaphambili lweklinikhi kunye neklinikhi luye lwafakazela ukuba ukuzila ngokukhawuleza, kwenziwe iintsuku eziliqela ezilandelelanayo, kungenelelo olunamandla kakhulu kangangokuba imizimba yethu ifunde ngokusemthethweni ukuhlangabezana nokukhusela nokuzihlaziya. Le mibini mibini yimiqathango yokulwa nokuguga enika iinkonzo ezongezelelweyo zezempilo. I-5-Day ProLon yokuzila ukutya okuxilisayo ihlolwe kwaye ifunyenwe ukukhuthaza imiphumo emihle kwiimeko ezahlukeneyo ezivela kwisisindo esithinteleyo kunye nokutya kwegazi kwi-glucose, kwiimeko zokukhula ezinxulumene nokulimala kweDNA nokuguga.

Min Wei; Sebastian Brandhorst et al.
Ukuzila ukutya? Ukulinganisa ukutya kunye neMingcipheko yokuguga, isifo seswekile, uMhlaza kunye nesifo senhliziyo.

Inkqubo ye-5-Day

Isicwangciso sokutya seProlon silandelwa iintsuku ze-5 ngenyanga. Xa umntu sele egqibile isicwangciso seentsuku ezintlanu, abuyele kwisiqhelo ukutya okunempilo iintsuku ezingamashumi amabini anesihlanu zokugqibela. Ukuzila ukutya kunye nesicwangciso seProlon kulandela isidlo esisezantsi sekhabhohayidrethi/iprotheyini kwaye iqulethe uhlobo olulungileyo lweeasidi ezinamafutha. Iresiphi ye-FMD igcina umzimba wakho ukwimo yohlobo lokuzila ukutya, nto leyo ebangela ukuba kukhuselwe amanyathelo aphuhliswe ngumzimba. Oku kubangela ukuba umzimba usebenze kakuhle, uvuselele iiseli, kwaye uphumelele.

Unboxing the ProLon Fasting Mimicking Diet

Izifo ezinxulumene nobudala: I-Revolution Is Coming

Ndandisandul 'u kufunda incwadi ebizwa ngokuthi i-Long-Diet Diet: Fumana i-New Science emva kwe-Cell Stem Activation kunye noKuvuselela Ukuguga ngokukhawuleza, ukulwa nezifo, kunye nokwandisa ubukhulu, eyabhalwa nguValter Longo, PhD, 1 ongumlawuli we-Longevity Institute kwiYunivesithi yaseSouthern California kunye nososayensi oyintloko ekuphuhliseni nasekufundeni ukutya okulingisa ukuzila (FMD). Ndilandele umsebenzi kaGqr. Longo iminyaka emininzi ngokuncoma okukhulu. Uye wapapashwa kwiijenali ezikumgangatho ophezulu. Kwincwadi yakhe, uGqr. Longo ubhala malunga nezinto ezifunyanisiweyo ezinomdla malunga neqela lophando lwe-FMD elibandakanya iimpuku ezineenyanga ezili-16 ubudala, ezichazwa njengezilingana nomntu oneminyaka engama-45 ubudala: �Inkqubo exhomekeke kwi-stem cell ivuselelwe. amajoni omzimba. Ukuhlaziywa kwakhona kwenzeka kwisibindi, izihlunu kunye nengqondo. Amanqanaba eentlobo ezininzi zeeseli ze-stem ayanda.�1 Wahlabela mgama wachaza: �Ukuzila ukutya kona kutshabalalisa iiseli ezininzi ezonakalisiweyo kunye namalungu awonakeleyo ngaphakathi kweeseli kodwa kuphinde kusebenze iiseli.

Jeffrey S. Bland, PhD, FACN, FACB, Associate Editor

Ukuzila ukutya-Ukuxilisa ukutya kukukhuthaza ukuhlaziywa kweB-Cell ukuguqula isifo sikashukela

• Ukuzila ukutya ukuxelisa ukutya kukukhuthaza ukubonakalisa ukuveliswa kokubeletha komntwana kwi-pancreas yabantu abadala
• I-FMD ikhuthaza ibinzana leNgn3 ukuvelisa iiseli ezivelisa i-insulin
• Imijikelezo ye-FMD ibuyisela ukuhluleka kwe-b-cell kunye namagundane okuhlangula kwi-T1D ne-T2Dd
• Inhibition ye-PKA okanye i-MTOR ikhuthaza i-NN3 eqhutyelwa yi-b-cell ukuhlaziywa kwiipropthi ze-T1D zabantu

Iimvavanyo zise-stem-based ziyakwazi ukuguqula izidakamizwa zesifo kunye nezifo, kodwa ukususwa kweethambo ezinokukhubazeka kunye nokuqaliswa kwenkqubo ekhokelela ekuhlaziyweni komzimba kuyimingeni emikhulu. Kwiigundane, ukuzila ukudla kwexesha le-4 yokutya okufanayo (FMD) kukhuthaza ukubonakalisa ukuhamba kwe-Sox17 kunye ne-Pdx-1, ilandelwa isizukulwana esenziwa yi-Ngn3 yeeseli ezivelisa i-insulin, efana neyabonwa ngexesha lophuhliso lwe-pancreatic. Imijikelezo ye-FMD ibuyisela ukugcinwa kwe-insulini kunye ne-homeostasis ye-glucose kwimizi yomibini i-2 kunye nohlobo lwe-1diabetes yemouse.

Kuhlobo lwabantu lwe-1 i-diabetes pancreatic islets, iimeko zokuzila ziyanciphisa iPKA kunye nomsebenzi we-MTOR kwaye zenza i-Sox2 kunye ne-Ngn3Indlululo kunye nokuveliswa kwe-insulin. Imiphumo ye-FMD iguqulwa ngonyango lwe-IGF-1 kwaye iphinda iphinde iphunyezwe yi-PKA kunye ne-MTOR inhibition. Ezi ziphumo zibonisa ukuba i-FMD igqugquzela ukutshayelwa kabusha kweeseli zepancreatic ukubuyisela isizukulwana se-insulin kwizilwanyana ezivela kwizigulane ze-T1D kwaye ziguqule zombini ii-T1D kunye ne-T2D ze-phenotypes kwimifanekiso yamagundane.

I-Chia-Wei Cheng, 1,6,7Valentina Villani, 2,7Roberta Buono, 1,5,7Min Wei, 1Sanjeev Kumar, 4Omer H. Yilmaz, 6Pinchas Cohen, 1Julie B. Sneddon, 3Laura Perin, 2and Valter D. Longo1,4,5,8, *