Uqhagamshelo lwe-thyroid kunye ne-Autoimmunity

Idlala lengqula yinto encinci, emile okwibhabhathane ebekwe entanyeni ngaphambili evelisa i-T3 (triiodothyronine) kunye ne-T4 (tetraiodothyronine) hormone. Ezi hormone zichaphazela zonke izicubu kunye nokulawula imetabolism yomzimba ngelixa liyinxalenye yenethiwekhi entsonkothileyo ebizwa ngokuba yinkqubo ye-endocrine. Inkqubo ye-endocrine inoxanduva lokulungelelanisa imisebenzi emininzi yomzimba. Kwinyama yomntu, la manyala mabini e-endocrine yeyona gland kunye namadlala adrenal. I-thyroid ilawulwa ngokuyintloko yi-TSH (i-hormone evuselela i-thyroid), ekhushulwe kwilungu lesikhumba esisengqondweni. Indlala ye-anterior pituitary inokukhuthaza okanye inqamle imfihlo kwimithambo yethambo, okuyimpendulo kuphela kwendlala emzimbeni.

Kuba idlala lengqula lenza i-T3 kunye ne-T4, iodine ikwanokunceda kwimveliso yehomoni yedlala lengqula. Idlala lengqula lilo kuphela elinokufunxa iodine ukunceda ukukhula kwehomoni. Ngaphandle kwayo, kunokubakho iingxaki ezinje ngehyperthyroidism, hypothyroidism, kunye nesifo sikaHashimoto.

Impembelelo ze-thyroid kwiiSistim zoMzimba

Idlala lengqula linokunceda ukuhambisa umzimba, njengokulawula ukubetha kwentliziyo, ubushushu bomzimba, uxinzelelo lwegazi kunye nokusebenza kwengqondo. Uninzi lweeseli zomzimba zinee-receptors ze-thyroid ezisabela kuzo. Nazi iinkqubo zomzimba ezincedwa yi-thyroid.

Inkqubo yeNtliziyo kunye neThumba leNtsholongwane

Kwiimeko eziqhelekileyo, iihomoni ze-thyroid zinceda ukwanda kokuhamba kwegazi, ukuphuma kwentliziyo, kunye nenqanaba lentliziyo kwinkqubo yentliziyo. Idlala lengqula linokuchaphazela ukonwaba kwentliziyo, elibangele ukuba libe nemfuno ekhulayo yeoksijini, ke ngoko yonyusa imetabolites. Xa umntu esenza umthambo; amandla abo, imetabolism, kunye nempilo yabo iyonke, baziva bonwabile.

I-thyroid yinyani yomeleza umsipha wentliziyo, ngelixa kunciphisa uxinzelelo lwangaphandle kuba ihlaziya umsipha oburhabaxa bemisipha. Oku kubangela ukwehla kokunganyangeki kwe-arterial kunye noxinzelelo lwegazi lwegazi kwenkqubo yeentliziyo.

Xa kukho isixa esigqithisileyo sehomoni yedlala lengqula, inokunyusa uxinzelelo lokubetha kwentliziyo. Ayisiyiyo loo nto kuphela, inqanaba lentliziyo elibuthathaka kakhulu kukunyuka okanye ukwehla kwehomoni yedlala lengqula. Kukho iimeko ezimbalwa ezinxulumene nentliziyo ebhalwe apha ngezantsi enokuba sisiphumo sokwanda okanye ukwehla kwehomoni yedlala lengqula.

• Syndrome yeMetabolic
• U xinzelelo
• Hypotension
• IAnemia
• Arteriosclerosis

Into ebangela umdla kukuba, ukusilela kwentsimbi kunokucothisa iihomoni ze-thyroid kunye nokwandisa ukuveliswa kweehomoni ezibangela iingxaki kwinkqubo yentliziyo.

Inkqubo yeGastrointestinal kunye ne-thyroid

I-thyroid inceda inkqubo ye-GI ngokunyusa i-carbohydrate metabolism kunye ne-metabolism yamafutha. Oku kuthetha ukuba kuya kubakho ukwanda kweglucose, iglycolysis, kunye negluconeogene kunye nokukhupha okwandileyo kwitreyini ye-GI kunye nokunyuka kwe-insulin. Oku kwenziwa ngokunyuka kwemveliso ye-enzyme evela kwi-hormone ye-thyroid, isebenze kwi-nucleus yeeseli zethu.

I-thyroid inokwenyusa izinga le-basal metabolic ngokunceda ngokunyusa isantya sokwehla, ukufunxa, kunye nokunyusa izondlo esizityayo kunye nokuphelisa inkunkuma. Ihomoni ye-thyroid inokonyusa isidingo seevithamini zomzimba. Ukuba i-thyroid iya kulawula i-metabolism yeseli yethu, kuya kubakho isidingo esongezelelweyo seevithamini cofactors kuba umzimba udinga iivithamini ukwenza ukuba usebenze ngokufanelekileyo.

Iimeko ezithile inokuchatshazelwa ngumsebenzi we-thyroid, kwaye ngokungenabungozi kunokubangela ukungasebenzi kakuhle kwe-thyroid.

• I-metabolism ye-cholesterol engaqhelekanga
• Ukutyeba / ukutyeba kakhulu
• Ukusilela kweVitamin
• Ukuqunjelwa / iswekile

IiHormones zesondo kunye neThumba eliDibeneyo

Ihomoni ye-thyroid inefuthe ngqo kwii-ovari kunye nefuthe elingathanga ngqo kwi-SHBG (i-hormone yesondo ebopha i-globulin), i-prolactin, kunye ne-gonadotropin-ekhulula secretion yehomoni. Abasetyhini bachatshazelwa kakhulu ziimeko ze-yegilo kunamadoda ngenxa yehomoni nokukhulelwa. Kukho enye into enegalelo ekwabelwana ngayo nabasetyhini, iivithamini ze-iodine yazo kunye neehomoni ze-thyroid ngokusebenzisa ii-ovari kunye nezicubu zesifuba emizimbeni yabo. I-thyroid inokuba nesizathu okanye igalelo kwiimeko zokukhulelwa ezifana:

• Ukufikisa ngobunyani
• Imicimbi yokuya esikhathini
• Imicimbi yokuzala
• Amanqanaba ama-hormone angaqhelekanga

I-HPA Axis kunye ne-thyroid

Isitshixo se-HPA (Hypothalamic-Pituitary-Adrenal Axis) imodareyitha impendulo yoxinzelelo emzimbeni. Xa oko kusenzeka, i-hypothalamus ikhupha i-hormone ekhupha i-corticotropin, ibangela i-ACH (i-acetylcholine hormone) kunye ne-ACTH (i-adrenocorticotropic ihormoniukwenza kwi-adrenal gland ukukhupha i-cortisol. ICortisol yincindi yedlala yoxinzelelo enokunciphisa ukudumba kunye nokwandisa imetabolism yomzimba emzimbeni. Inokubangela kwakhona ukubakho kweekhemikhali ze-armalarm ezifana ne-epinephrine kunye ne-norepinephrine (umlo okanye impendulo yendiza). Ukuba kukho ukungabikho kwe-cortisol ethotyiweyo, umzimba uya kuyikhathalela i-cortisol kunye nokuphendula koxinzelelo, into elungileyo leyo.

Xa kukho inqanaba eliphezulu le-cortisol emzimbeni, iya kunciphisa umsebenzi we-thyroid ngokunciphisa ukuguqulwa kwehomoni ye-T4 kwi-hormone ye-T3 ngokuphelisa i-deiodinase enzymes. Xa oku kusenzeka, umzimba uya kuba ne-thyroid engasebenzi kangako, kuba umzimba awunokwazi ukuxelela usuku oluxakekileyo emsebenzini okanye ubaleka into eyoyikisayo, kunokuba yinto elungileyo okanye eyoyikisayo.

Iingxaki ze-thyroid emzimbeni

I-thyroid iyakwazi ukuvelisa iihomoni ezininzi emzimbeni okanye zingabikho ngokwaneleyo emzimbeni, zibangela iingxaki zempilo. Ezantsi apha ezona ngxaki ziqhelekileyo ze-thyroid eziya kuthi zichaphazele i-thyroid emzimbeni.

• Hyperthyroidism: Eli xa i I-thyroid iyasebenza, Ukuvelisa isixa esigqithisileyo samahomoni. Ichaphazela malunga ne-1% yabasetyhini, kodwa ayiqhelekanga kumadoda ukuba nayo. Ingakhokelela kwiimpawu ezinje ngokungahlaliseki, amehlo aqumbe, ubuthathaka bemisipha, isikhumba esibhityileyo kunye noxinzelelo.
• Ingqondo: Oku ke ngokuchasene ne-hyperthyroidism kuba ayinakuvelisa iihormoni ezaneleyo emzimbeni. Ihlala ibangelwa sisifo sikaHashimoto kwaye inokukhokelela kulusu olomileyo, ukudinwa, iingxaki zememori, ukuzuza ubunzima, kunye nokubetha kwentliziyo kancinci.
• Isifo sikaHashimoto: Esi sifo saziwa njenge Unyango lwe-thymitis engapheliyo. Ichaphazela malunga nezigidi ezili-14 zaseMelika kwaye inokwenzeka kwabafazi abaneminyaka ephakathi. Esi sifo sikhula xa amajoni omzimba ehlasela ngempazamo kwaye ngokuthe chu atshise idlala lengqula kunye namandla alo okuvelisa iihomoni. Ezinye zeempawu ezibangelwa sisifo sikaHashimoto bubuso obumhlophe, obukhukhumeleyo, ukudinwa, i-thyroid eyandisiweyo, ulusu olomileyo kunye noxinzelelo.

isiphelo

Idlala lengqula libinzana elime bhabhathane elikwintamo engaphandle evelisa iihomoni ezinceda ukusebenza komzimba wonke. Xa ingasebenzi ngokuchanekileyo, inokudala isixa esigqithisileyo okanye inciphise inani lamahomoni. Oku kubangela ukuba umzimba womntu uvelise izifo ezinokuba lixesha elide.

Ukuhlonipha ukubhengezwa kweRhuluneli u-Abbott, u-Okthobha yinyanga yeMpilo yeChiropractic. Ukuze ufunde ngakumbi malunga nesindululo kwiwebhusayithi yethu.

Ubungakanani bolwazi lwethu lukhawulelwe kwi-chiropractic, musculoskeletal, kunye nemicimbi yezempilo yovalo kunye namanqaku amayeza asebenzayo, izihloko kunye neengxoxo. Sisebenzisa iiprothokholi zempilo ezisebenzayo ukunyanga ukwenzakala okanye ukuphazamiseka okungapheliyo kwenkqubo yemusculoskeletal. Ukuqhubeka nokuxoxa ngomxholo ongentla, nceda ukhululeke ukubuza uGqirha Alex Jimenez okanye unxibelelane nathi apha 915-850-0900 .

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Iingxelo:

Melika, iVibrant. HyThyroid kunye nokuzimela ngokuzenzekelayo YouTube, IYouTube, 29 kweyeSilimela 2018, www.youtube.com/watch?feature=youtu.be&v=9CEqJ2P5H2M.

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Abasebenzi beKlinikhi, iMayo. IHypothyroidism (i-Thyroid engasebenziyo) Clinical Mayo, Isiseko se-Mayo sezeMpilo kunye noPhando, i-4 Dec. 2018, www.mayoclinic.org/diseases-conditions/hypothyroidism/sy iimpawu-causes/syc-20350284.

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UStephens, uMary Ann C, kunye noGary Wand. Uxinzelelo kunye ne-HPA Axis: Indima yeGlucocorticoids kuTywala ukuxhomekeka. Uphando ngotywala: Uhlalutyo lwangoku, IZiko leSizwe ngokuSetyenziswa gwenxa kotywala kunye noTywala, i-2012, www.ncbi.nlm.nih.gov/pmc/articles/PMC3860380/.

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