Njengoko umzimba uguga, abantu bafuna ukuhlala bekhuthele kwaye bagcine impilo esempilweni engenazintlungu. Ngaba iiseli zokuvuselela i-arthritis kunye nomonakalo we-cartilage ibe likamva leyeza le-neuromusculoskeletal kunye nokuphilisa ngokubambisana?
Contents
Iiseli ezihlaziyiweyo ze-Arthritis kunye nomonakalo weCartilage
Abantu bafuna ukuqhubeka nokwenza imisebenzi yomzimba abayithandayo, efuna amalungu aphilileyo. Izazinzulu zifunda ukusebenzisa ubuchule beeseli ezihlaziyayo ukuze ziphinde zikhule intlala eyonakeleyo neyonakeleyo. Unyango lwangoku lwe-stem cell yeengxaki ze-cartilage aluzange luboniswe ukuguqula imiphumo ye-arthritis kwaye ngelixa izifundo zibonisa ukuphuculwa kwekliniki, uphando olongezelelweyo luyimfuneko. (UBryan M. Saltzman, et al., 2016)
ICartilage kunye nendlela eyonakaliswa ngayo
ICartilage luhlobo lwethishu edibeneyo. Kumalungu, kukho iindidi ezimbalwa ze-cartilage. Eyona nto ixhaphakileyo kubhekiselwa kuyo yintambo egudileyo eyaziwa ngokuba yi-articular okanye i-hyaline cartilage. Olu hlobo lwenza umaleko ogudileyo womqamelo ekupheleni kwethambo kwindawo edibeneyo. (Rocky S. Tuan, et al., 2013)
- Ithishu yomelele kakhulu kwaye inamandla okucinezela nokufunxa amandla.
- Igudile kakhulu ivumela ilungu ukuba lityibilike ngaphandle komgudu kuluhlu lwentshukumo yelungu.
- Xa i-cartilage edibeneyo ibonakaliswe, i-cushioning ingaphelelwa.
- Kwiinzakalo ezibuhlungu, amandla ngokukhawuleza anokubangela ukuba i-cartilage iphule kunye / okanye ihlupheke umonakalo, obonisa ithambo elingaphantsi.
- Kwi-osteoarthritis - i-arthritis ephazamisayo okanye egugileyo, i-layer egudileyo inokuguga kwaye iyancipha kwaye ingalingani.
- Ekugqibeleni, i-cushion iyaphela, amalungu avutha kwaye adumbe kwaye iintshukumo ziba nzima kwaye zibuhlungu.
Kukho unyango lwe-arthritis kunye nomonakalo we-cartilage, kodwa olu nyango luhlala lujolise ekupheliseni iimpawu ngokulungisa i-cartilage eyonakeleyo okanye ukubuyisela indawo edibeneyo kunye nokufakelwa okwenziweyo, njengokutshintshwa kwedolo okanye utyando lokutshintshwa kwe-hip. (Robert F. LaPrade, et al., 2016)
Iiseli ezivuselelayo
Iiseli ze-stem ezivuselelayo ziiseli ezikhethekileyo ezikwaziyo ukuphindaphinda kunye nokuphuhlisa kwiintlobo ezahlukeneyo zezicubu. Kwisetingi yotyando lwamathambo kwiingxaki ezidibeneyo, iiseli ze-stem zifumaneka kwimithombo ephambili yeseli ye-stem eyi-bone umongo kunye nezicubu ezinamafutha. Ezi seli zinamandla okuphuhlisa iiseli ze-cartilage, ezibizwa ngokuba yi-chondrocytes. (Rocky S. Tuan, et al., 2013)
- Zikwanceda ngokuvuselela umzimba ukuba unciphise ukudumba, ukuvuselela ukulungiswa kweeseli, nokuphucula ukuhamba kwegazi.
- Le nkqubo ibangelwa izibonakaliso zeselula kunye nezinto zokukhula ukukhuthaza umzimba ukuba usebenze iinkqubo zokuphilisa.
- Emva kokuba iiseli ze-stem zifunyenwe, kufuneka zihanjiswe kwindawo yomonakalo we-cartilage.
I-Cartilage yi-tissue eyinkimbinkimbi echazwa njengesakhiwo se-scaffold esiqulunqwe yi-collagen, i-proteoglycans, amanzi kunye neeseli. (Rocky S. Tuan, et al., 2013)
- Ukuvuselela i-cartilage, izicubu eziyinkimbinkimbi kufuneka kwakhona zakhiwe kwakhona.
- Kukho izifundo kwiintlobo ze-scaffolds zezicubu ezenzelwe ukubuyisela uhlobo olufanayo lwesakhiwo se-cartilage.
- Iiseli ze-stem zinokuthi zifakwe kwi-scaffold, ngethemba lokubuyisela uhlobo oluqhelekileyo lwe-cartilage.
Unyango lwe-Arthritis olungelulo Utyando
umgangatho unyango ezifana ne-cortisone shots okanye unyango lomzimba lusebenza ngokunjalo kwaye lubonelela ngeenzuzo ezinokuthi zisetyenziswe ngokudibanisa neeseli ezivuselelayo ze-arthritis kunye nomonakalo we-cartilage kwixesha elizayo elikufutshane. Idatha ithatha ixesha kwaye ngoko ke oku kuchaphazela njani impilo yexesha elide leemfuno ezidibeneyo eziqhubekayo uphando malunga nobunjineli bezicubu kunye nokuhanjiswa kweeseli ukumisela eyona ndlela yokunceda abantu.
Arthritis
Ucaphulo
LaPrade, RF, Dragoo, JL, Koh, JL, Murray, IR, Geeslin, AG, & Chu, CR (2016). I-AAOS yoPhando lwe-Symposium Updates and Consensus: Unyango lwe-Biologic ye-Orthopedic Injuries. Umbhalo we-American Academy of Orthopedic Surgeons, 24 (7), e62-e78. doi.org/10.5435/JAAOS-D-16-00086
Saltzman, BM, Kuhns, BD, Weber, AE, Yanke, A., & Nho, SJ (2016). Iiseli zeStem kwi-Orthopedics: IsiKhokelo esiBanzi seGqirha ye-Orthopedist. Ijenali yaseMelika yamathambo (Belle Mead, NJ), 45 (5), 280-326.
Tuan, RS, Chen, AF, & Klatt, BA (2013). Ukuhlaziywa kweCartilage. Ijenali ye-American Academy ye-Orthopedic Surgeons, i-21 (5), i-303-311. doi.org/10.5435/JAAOS-21-05-303
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Iintsikelelo
UDkt Alex Jimenez D.C., I-MSACP, RN*, I-CCST, IFMCP*, I-CIFM*, I-ATN*
email: qeqeshi@elpasofunctionalmedicine.com
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Ubume obubambeneyo: ILayisensi yeeNkcazo ezininzi: Ugunyaziswe Ukuziqhelanisa I-40 States*
UGqr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
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