Iiprotheyini ezinokuthintela njani impilo yeNtliziyo I kliniki yo kuphila

Iprotheyini yinxalenye ebalulekileyo yesondlo esilungeleleneyo. Umzimba womntu usebenzisa iprotheyini ukwakha kunye nokulungisa izicubu. Iprotheyini ikwasetyenziselwa ukwenza ii-enzymes, iihomoni, kunye nezinye iikhemikhali ezisisiseko zomzimba. Iprotheyini sisakhiwo esibalulekileyo sokwakha amathambo, izihlunu, intlala, ulusu kunye negazi. Nangona kunjalo, kubantu abaninzi, umthombo wezi proteni unokuhlala ugcwele ngamafutha ahluthayo, kwaye uninzi lwayo lunokunyusa umngcipheko wesifo sentliziyo.

Ngaba iiprotheyini zinokubangela isifo sentliziyo kunye noxinzelelo lwegazi?

Iprotein inokufumaneka kwinkukhu, kwihagu, kwintlanzi, kwinyama yenkomo, kwitofu, kwiimbotyi, kwilentile, iyogathi, ubisi, itshizi, imbewu, amandongomane namaqanda. Umba wokutya eminye yale mithombo yeprotheyini etyebe ngamafutha ahluthayo ngokunjalo kukuba oko kunokunyusa amanqanaba e-low-density lipoprotein cholesterol (LDL), okanye ngamanye amazwi, i-cholesterol “embi”. Ukunyuka kwamanqanaba e-cholesterol ye-LDL kuye kwadibaniswa nesifo senhliziyo kunye noxinzelelo lwegazi. Uphononongo lophando olujolise kunxibelelwano phakathi kweprotheyini yokutya kunye ne-CVD kunye noxinzelelo lwegazi luye lwenziwa ukuveza oku kuhambelana.

Iiprotheyini kunye nesifo se-Cardiovascular

Ucwaningo lwe-Observational and epidemiologic lubonise ukuhla kwengcinezelo yegazi, okanye i-BP, kunye nobudlelwane obuhambelanayo phakathi kokusetyenziswa kweeprotheyini eziphezulu kunye nesiganeko se-BP. Umthombo weprotheyini yinto ebalulekileyo xa kuziwa kwimpembelelo yoxinzelelo lwegazi emzimbeni; apho iprotein yezilwanyana iye yasebenza kancinci kuneprotein engeyiyo eyesilwanyana okanye yezityalo, ngakumbi ezo kwiialmondi. Kwi-Inter-Salt Study yezifundo ezingaphezu kwe-10,000, abantu abasebenzisa iprotheyini yokutya malunga neepesenti ze-30 ngaphezu komyinge banciphise i-BP nge-3.0 / 2.5 mmHg xa kuthelekiswa nalawo ayengama-30 ekhulwini ngaphantsi komyinge. Nangona kunjalo, iprotheni yezilwanyana zasendle okanye ezityebileyo ezinamafutha abalulekileyo kunye nangaphantsi kunye nee-acids ezinamafutha anokunciphisa i-CHD, i-lipids kunye ne-BP ingozi.

Uhlalutyo lwe-meta luxhase ezi ziphumo kwaye lubonise ukuba abantu abane-hypertensive kunye nabantu abadala banokuncitshiswa kwe-BP kunye nokutya kweprotheni. Ukanti enye i-meta-analysis yezilingo ze-40 kunye nezigulane ze-3277 zifumene ukunciphisa kwi-BP ye-1.76 / 1.15 mmHg xa kuthelekiswa nokusetyenziswa kwe-carbohydrate (p <0.001). Zombini iiprotheyini zemifuno kunye nezilwanyana ngokuphawulekayo kwaye ngokulinganayo zinciphisa i-BP kwi-2.27 / 1.26 mmHg kunye ne-2.54 / 0.95 mmHg ngokulandelanayo. Ukusetyenziswa kweprotheyini yokutya kuhambelana ngokuphambene nomngcipheko we-stroke. Uphononongo olungahleliwe olunqamlezileyo kubantu abadala be-352 abane-pre-hypertension kunye ne-stageIhypertension ifumene ukwehla okukhulu kwe-SBP ye-2.0 mmHg kunye neprotheni ye-soy kunye ne-2.3 mmHg kunye neprotheni yobisi xa kuthelekiswa ne-high glycemic index yokutya kwixesha ngalinye le-8 wk unyango. Ukuhla okungabalulekanga kuye kwaba kwi-DBP. Olunye uphando lwe-RDB oluhambelanayo kwiiveki ze-4 zezifundo ze-94 ezine-prehypertension kunye ne-stageIhypertension ifumene ukunciphisa okukhulu kwi-ofisi ye-BP ye-4.9 / 2.7 mmHg kulabo banikwe i-combo ye-25 yepesenti ye-protein intake vs iqela lolawulo elinikezelwa i-15 yepesenti yeprotheyini ngendlela ye-isocaloric. Iprotheyini yayiquka i-ertyisi, i-20 yepesenti yesoya, iqanda elingama-30 ekhulwini kwaye lizimele. Ukutya okucetyiswayo kwansuku zonke kwimithombo emininzi yi-1.0 ukuya kwi-1.5 g / kg ubunzima bomzimba, ukuhluka kwinqanaba lokuzivocavoca, ubudala, umsebenzi wezintso kunye nezinye izinto.

Ubisi oluvundisiweyo oludityaniswe ne-whey protein concentrate luyayinciphisa i-BP. Iipeptide zobisi, ezilinganayo iicasein kunye neeproteni ze-whey, zingumthombo ocebileyo we-ACEI peptides. I-Val-Pro-Pro kunye ne-Ile-Pro-Pro enikezelwa kwi-20 ukuya kwi-6 mg / d inokunciphisa okuhlukeneyo kwi-BP usebenzisa ukunciphisa okuqhelekileyo kwizifundo ezidibeneyo malunga ne-8.0-3.2 / 5.5-2.1 mmHg. Nangona kunjalo uhlalutyo lwe-meta lwakutshanje aluzange lubonakalise ukunciphisa okukhulu kwi-BP kubantu. Ubisi oluvundisiweyo oluyimpuphu usebenzisa i-Lactobacillus helveticus enikwe kwi-5 g / d yehlisa kakhulu i-BP ukusuka kwi-60 / 1.28 mmHg kwiiveki ezi-4.8. Uphononongo lwempendulo yedosi lubonakalise ukuncitshiswa kweBP. Impendulo ibalelwa kwiipeptide zobisi ezivundisiweyo ezithintela i-ACE.

Izikhonkwane et al zilawulwa yi-20 g yeprotheni ye-whey e-hydrolyzed kwaye yaqaphela ukuba ukunciphisa i-BP ye-11 / 7 mmHg xa kuthelekiswa nokulawula. Iprotheni ye-Whey iphumelele ekuphuculeni ukuqina kwe-arterial, ukumelana ne-insulin, i-glucose, i-lipids kunye ne-BP. Ezi datha zibonisa ukuba iprotheyini kufuneka ifakwe i-hydrolyzed ukuze ibonise umphumo we-antihypertensive, kwaye kwakhona ubuninzi bokusabela kwe-BP kuxhomekeke kwidosi. Iipeptide zenkomo kunye ne-whey peptides eziphuma kwiprotheni zibonisa umsebenzi we-ACEI. Ezi zixhobo ziquka i-B-caseins, i-B-lg B2-microglobulin, amaqhezu kunye ne-serum albumin. I-ACEI peptides ikhutshwa yi-hydrolysis ye-whey protein isolate. I-collagen peptides yaselwandle (MCPs) evela kwintlanzi yolwandle olunzulu inomsebenzi wokuchasana noxinzelelo lwegazi. Uvavanyo olulawulwa yi-placebo oluyimfama oluphindwe kabini kwizifundo ze-100 ze-hypertension ezinesifo sikashukela ezifumana i-MCPs kabini ngosuku kwiinyanga ze-3 ziye zanciphisa kakhulu kwi-DBP kunye nentsingiselo. Iprotheni ye-Bonito (i-Sarda Orietalis), evela kwintsapho ye-tuna kunye ne-mackerel ine-ACEI yendalo ye-peptides inhibitory kunye nokunciphisa i-BP 10.2 / 7 mmHg kwi-1.5 g / d.

Iprotheni ye-sardine muscle, equkethe i-Valyl-Tyrosine (VAL-TYR), iyancipha kakhulu i-BP kwizifundo eziphezulu. U-Kawasaki et al waphatha izifundo ze-29 ze-hypertensive kunye ne-3 milligrams ye-VAL-TYR ye-sardine muscle egxininise isicatshulwa kwi-wk ezine kunye nokunciphisa i-BP 9.7 / 5.3 mmHg (p <0.05). Amanqanaba e-aldosterone kunye ne-A-Inyuswe njenge-serum A-II iyancipha iphakamisa ukuba i-VAL-TYR yi-ACEI. I-BP yancitshiswa kakhulu kwisifundo kusetyenziswa isiselo semifuno kunye neprotheyini ye-hydrolysates kwiiveki ze-13.

Iprotheni ye-Soy iyanciphisa i-BP kwizigulane kwizifundo ezininzi. Ukusetyenziswa kweeprotheyini ze-Soy kwakuchasene kwaye kuhambelana kakhulu kunye ne-DBP kunye ne-SBP kwi-45694 amantombazana aseTshayina okanye ngaphezulu kweprotheni ye-soy kwiminyaka eyi-3 kwaye umbutho wanda ngokukhula. Ukuncipha kwe-SBP kwaba ngu-1.9 ukuya kwi-4.9 mm encitshisiweyo kunye ne-DBP 0.9 ukuya kwi-2.2 mmHg ephantsi. Nangona kunjalo, uhlalutyo lweemeta kunye nezilingo zibonise iziphumo ezixubileyo kwi-BP ekunciphiseni ipesenti ze-7 ukuya kwi-10 ipesenti ye-SBP kunye ne-DBP ngaphandle kotshintsho kwi-BP. Uhlalutyo lwe-meta lwangoku lwezilingo ze-27 lufumene ukunciphisa okukhulu kwi-BP ye-2.21 / 1.44 mmHg. Ezinye izifundo zibonisa ukuphuculwa komsebenzi we-ACEI, ukunciphisa ukuvuvukala kunye ne-HS-CRP, umsebenzi wokuqonda ukuthotyelwa kwe-arterial, ukunciphisa umsebenzi wetoni kunye nokunciphisa zombini uxinzelelo lwe-oxidative kunye namanqanaba. Isoya evundisiweyo malunga ne-25 g/d iyacetyiswa.

Ngaphandle kweziphumo ze-ACEI, ukusetyenziswa kweprotheyini kunokutshintsha iimpendulo kwaye kubangele i-natriuretic. Ukuthathwa kweprotheyini ephantsi kunye ne-omega ephantsi ye-3 ye-fatty acid ethathayo kunokukhokelela kuxinzelelo lwegazi kwiimodeli zezilwanyana. Iprotheyini efanelekileyo, esekelwe kwiqondo lomsebenzi, umsebenzi wezintso, uxinzelelo kunye nezinye izinto, malunga ne-1.0 ukuya kwi-1.5 g / kg imihla ngemihla.

Ukuqukumbela, iprotheyini iyinxalenye ebalulekileyo yokutya okunokulinganisela, nangona kunjalo, ezinye iindlela ezinqabileyo eziqulethe ixabiso elincinci lamafutha agcweleyo zifanelekile ukukhusela umngcipheko wesifo senhliziyo kunye noxinzelelo lwegazi, ukukhuthaza impilo yonke kunye nokuphila kakuhle. Abantu abaninzi batya izixa eziphezulu zeeprotheyini kunokuba kuyimfuneko. Ingcali yezempilo ejongene nokutya kunye nesondlo inokukunceda uze nesona sicwangciso sesondlo sezempilo sakho kunye neenkxalabo zakho zempilo. Ubungakanani bolwazi lwethu lukhawulelwe kwi-chiropractic kunye nokulimala komgogodla kunye neemeko. Ukuxoxa ngombandela, nceda uzive ukhululekile ukubuza uDkt Jimenez okanye uqhagamshelane nathi 915-850-0900 .

NguDkt Alex Jimenez

Imixholo eyongezelelweyo: Ubungakanani

Impilo kunye nokuphila kakuhle kubalulekile ekugcineni ukulinganisela kwengqondo kunye nomzimba emzimbeni. Ukutya ukutya okunokulinganisela kunye nokuthatha inxaxheba kwimisebenzi engokwenyama, ukulala ixesha elinempilo ngokuqhelekileyo, ukulandela iziphumo ezingcono zezempilo kunye neempilweni zokugcina unokukunceda ekugcineni ulondoloze impilo yonke. Ukutya ezininzi iziqhamo nemifuno kunokuhamba ixesha elide ekuncedeni abantu ukuba baphile.

INGXELO YOKUPHATHA: I-EXTRA EXTRA: Mayelana neChiropractic