Iinkqubo phakathi kweVisceral Hypersensitivity kunye neThumbu

intshayelelo

Isisu sesisu okanye Inkqubo yamathumbu inceda ukulungelelanisa i-homeostasis yomzimba kunye ne-metabolize inkqubo yomzimba. Ngoqhagamshelo lwayo kwi ngengqondo, i-gut inokunceda ukuthutha izondlo kunye nolwazi olongezelelweyo kwiimisipha ezihambelanayo, izicubu kunye nezitho ukuba zisebenze. Ezi zihlunu, izicubu, kunye namalungu onke anomsebenzi ekufuneka wenziwe kwaye ancede umzimba uhlale usempilweni kwizinto zangaphakathi nangaphandle ezinokulimaza inkqubo yamathumbu. Xa izinto zangaphakathi ziphazamisa inkqubo yamathumbu, kunokukhokelela kwiimpawu ezahlukahlukeneyo ezichaphazela amathumbu kunye nezitho zangaphakathi kunye nezihlunu ezijikeleze inkqubo yamathumbu. Inqaku lanamhlanje lijonga enye yokuphazamiseka kwamathumbu eyaziwa ngokuba yi-irritable bowel syndrome kunye nefuthe layo kwi-lumbar back, kunye nendlela imiba yamathumbu emzimbeni eyenza ngayo i-visceral hypersensitivity. Sithumela izigulana kubaboneleli abaqinisekisiweyo, abanezakhono ezikhethekileyo kunyango lwesisu kunye nonyango lwe-chiropractic olunceda abo baphethwe yimiba yamathumbu afana nesifo se-bowel syndrome kunye neentlungu zangasemva. Sikwakhokela izigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo ibalulekile ekubuzeni imibuzo eqondayo kubaboneleli bethu. UDkt Alex Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli

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Irritable Bowel Syndrome echaphazela uMzimba

Ngaba uye wafumana ukudumba okungapheliyo emathunjini akho? Ngaba uziva ucinezelekile kakhulu kwaye uhlala echaphazela amathumbu akho? Ngaba ukutya okuthandayo kubangele imiba emathunjini akho? Ukufumana ezi mpawu ziimpawu zokuba unokuba ne-IBS okanye i-irritable bowel syndrome. Izifundo zophando ziye zachaza I-IBS njengenye yoxilongo oluqhelekileyo lwezifo zesisu. Xa umntu eqala ukuphuhlisa i-IBS kwinkqubo yabo yamathumbu, izinto ezininzi zinokudlala ezinokubangela uphuhliso. I-IBS idla ngokuqulunqwa xa kukho ukuphikisana kwiindonga zamathumbu. Oku kubangela ukuba ibhaktheriya yamathumbu ivuze kwaye ibangela ukuba amajoni omzimba ahlasele iindonga zamathumbu. Ezinye izifundo zophando zikhankanyile ukuba iziphumo ezivuthayo zingabangela i-visceral hypersensitivity ukuba ichaphazele umzimba ngokunyusa i-proinflammatory cytokines kwi-nerve ye-enteric kunye nokuba ne-mast cell count ephezulu. 

Izinto ezininzi ezinje ngomvandedwa wokutya, ukukhula kwebhaktiriya, i-visceral hypersensitivity, kunye nokudumba kwamathumbu zezinye zeziphumo ezahlukeneyo ze-pathology ye-IBS. Izifundo zophando zifumene ukuba xa indlela yokuphila iguqula inkqubo yamathumbu, inokudibaniswa nokungahambi kakuhle kwimimandla yesisu ngelixa ichaphazela ingqibelelo ye-biochemical. Izifundo zophando ezongezelelweyo zikhankanyiwe ukuba xa umntu ehlupheka nge-IBS, impembelelo yoxinzelelo inokubangela ukuba iintlungu ze-visceral ziphakame kwiindawo ezibangela ukuba izitho ezijikelezayo kwinkqubo yamathumbu zibe yi-hypersensitive. I-IBS ehambelana neentlungu ze-visceral inokuchaphazela kwakhona ummandla we-pelvic kunye nomqolo ophantsi, obangela enye isethi yemicimbi echaphazela umzimba. 

Isishwankathelo Sentlungu Yesisu-Ividiyo

Ngaba ubuziva ukudumba emathunjini akho? Ngaba umqolo wakho osezantsi okanye ummandla we-pelvic uqala ukuqaqamba okanye ukwenze uzive ungakhululekanga? Ngaba ukhe wafumana i-IBS okanye ezinye iingxaki zamathumbu? Uninzi lwezi mpawu zixhaphakile kubantu abane-IBS kunye neentlungu zesisu. Ividiyo engentla inika inkcazo ebalaseleyo yeengxaki ezintathu ezahlukeneyo ezinokuchaphazela ummandla wesisu somzimba. Uphando lophando lukhankanyile ukuba intlungu ye-visceral sisifo esintsonkothe ​​kakhulu esinokuchaphazela umntu onotshintsho okanye ongakhange abenalo naluphi na utshintsho kwisakhiwo okanye iziphene zemichiza echaphazela amathumbu akhe. Xa ithumbu lomntu liba yi-hypersensitive kwiintlungu ze-visceral, inokuchaphazela i-afferents eyahlukeneyo ukuba ivele xa i-lumbosacral intambo yomgogodla ikhula.

I-Visceral Hypersensitivity Ebangelwa YiMiba Yamathumbu

Xa i-visceral reflexes iba yi-hypersensitive, uphando lophando lufumene ukuba i-visceral hypersensitivity iye yaba ngumqondiso wekliniki kubantu abaphethwe yi-IBS. Ezinye zeempawu zinokubandakanya:

• Ukuhamba kwamathumbu rhoqo
• Ukuqhawula
• Intlungu zesisu

Olunye uphawu lwe-visceral hypersensitivity ngenxa ye-IBS kuxa igalelo le-nociceptive ukusuka kwikholoni enokuthi iholele inkqubo ye-gut ibe ne-hypersensitivity kwaye oku kunokunyusa ukunyanzeliswa kwamathumbu emathunjini okuguqula izicubu zesisu. Xa oku kusenzeka kunokubangela ukuba ii-microvessels zegazi zenze amanye amalungu ekujoliswe kuwo abe ne-hypersensitive nawo. Uphononongo olongezelelweyo lophando lufumene ukuba xa kukho iintlungu zesisu kwinkqubo yamathumbu kunokubangela ezinye iziphazamiso ezinjengeentlungu zesifuba ezingezizo zentliziyo kunye nezinye iimeko ezinokukhula kwizicubu ezijikelezayo emzimbeni. Xa abantu beqala ukwenza utshintsho oluncinci kwindlela yabo yokuphila, kunokuba luncedo kwezinye iinkqubo kunye nezihlunu ezichaphazelekayo.

isiphelo

Amathumbu okanye inkqubo yesisu inceda umzimba ukuba ulawule i-homeostasis yawo kwaye udibanise amajoni omzimba ukuze ugcine izihlunu kunye namalungu ajikelezileyo esebenza. Xa izinto zangaphakathi okanye zangaphandle zibangela iingxaki kwinkqubo yamathumbu, inokukhula ibe yi-IBS kwaye idibaniswe ne-visceral hypersensitivity kumalungu ahambelanayo kunye nezihlunu, ezibangela imiba eyahlukeneyo enokwenza umzimba ungasebenzi. I-lumbosacral intambo yomgogodla kunye neentsholongwane zayo ziba nzima kwaye zibangele i-pelvic kunye neentlungu ezisezantsi kwisiqingatha esisezantsi somzimba. Xa oku kusenzeka, umntu uya kuba lusizi kwaye achaphazele umgangatho wobomi bakhe. Ngokwenza utshintsho oluncinci lomkhwa ekunciphiseni i-IBS emathunjini, wonke umzimba uya kuqala ukuphilisa ngokwemvelo.

Ucaphulo

Umlimi, uAdam D, kunye noQasim Aziz. "Iintlungu zamathumbu kunye ne-Visceral Hypersensitivity." Ijenali yaseBritani yeentlungu, SAGE Publications, Feb. 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC4590155/.

Greenwood-Van Meerveld, Beverley, kunye no-Anthony C Johnson. "Uxinzelelo-olubangelwa yintlungu engapheliyo yeVisceral yemvelaphi yeGastrointestinal." Frontiers kwiiNkqubo zeNuroscience, Frontiers Media SA, 22 Nov. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5702626/.

Hadjivasilis, Alexandros, et al. "Ukuqonda okutsha kwi-Irritable Bowel Syndrome: Ukusuka kwi-Pathophysiology ukuya kuNyango." Annals of Gastroenterology, i-Hellenic Society ye-Gastroenterology, ngo-2019, www.ncbi.nlm.nih.gov/pmc/articles/PMC6826071/.

Mayer, EA, kunye neGF Gebhart. "Iinkalo ezisisiseko kunye neklinikhi ye-Visceral Hyperalgesia." Gastroenterology, ILayibrari yeSizwe yezeMithi yase-US, ngoJulayi 1994, yentshutshiso.ncbi.nlm.nih.gov/8020671/.

UPatel, uNicolas, kunye noKaren Shackelford. "I-Irritable Bowel Syndrome." Ku: StatPearls [Internet]. Isiqithi saseTreasure (FL), iStatPearls Publishing, 10 July 2021, www.ncbi.nlm.nih.gov/books/NBK534810/.

Saha, Lekha. "I-Irritable Bowel Syndrome: I-Pathogenesis, Ukuxilongwa, Unyango, kunye Nobungqina obuSekwe kuNyango." Ijenali yehlabathi ye-Gastroenterology, Baishideng Publishing Group Inc, 14 Juni 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC4051916/.

Zhou, QiQi, kunye noG Nicholas Verne. "Ukuqonda okutsha kwi-Visceral Hypersensitivity-Iimpembelelo zeKlinikhi kwi-IBS." Uphengululo lweNdalo. I-Gastroenterology kunye neHepatology, ILayibrari yeSizwe yezeMithi yase-US, ngoJuni 2011, www.ncbi.nlm.nih.gov/pmc/articles/PMC3437337/.

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