ULawula njani iimeko eziKhuselayo kunye neziZimeleyo kuMzimba

intshayelelo

Wonke umntu uzama ukwenza ukhetho lobomi obunempilo ngokubomeleza inkqubo yomzimba. Ukufumana okwaneleyo ukulala, ukutya okuninzi iziqhamo kunye nemifuno, ukusela kakhulu amanzi, yaye yokusebenzisa zonke zinceda ukwandisa amajoni omzimba. I-immune system iyaziwa ngokuba "ngumkhuseli" womzimba njengoko isusa abahlaseli bangaphandle abangena emzimbeni kwaye ibangele isiphithiphithi kwiinkqubo ezisebenzayo. I-immune system ikhupha iicytokines kubahlaseli bangaphandle ababangela ukuvuvukala kwindawo echaphazelekayo. Xa izinto zokusingqongileyo zichaphazela umzimba ngokuhamba kwexesha, amajoni omzimba ahlasela iiseli zawo ngempazamo, ecinga ukuba ngumhlaseli wangaphandle obangela i-autoimmunity. Inqaku lanamhlanje lijonga i-autoimmunity, i-triggers yalo, indlela ukuvuvukala kudlala ngayo indima yayo emzimbeni, kwaye yintoni i-DIRT Sithumela izigulane kubaboneleli abaqinisekisiweyo abakhethekileyo kwiindlela zonyango zonyango ukuze bancede abantu abaninzi abajongene nezifo ezizimeleyo kunye nokuvuvukala. Sikwakhokela izigulana zethu ngokubhekisa kubaboneleli bethu bezonyango abanxulumeneyo ngokusekelwe kuvavanyo lwabo xa kufanelekile. Sifumanisa ukuba imfundo sisisombululo sokubuza ababoneleli bethu imibuzo ecacileyo. UDkt Alex Jimenez DC unikezela ngolu lwazi njengenkonzo yemfundo kuphela. isikhanyeli

Yintoni i-Autoimmunity?

Ngaba ujongene nemiba yesisu echaphazelayo xa udla into ethile? Kuthekani ngeentlungu kunye nokudumba kumalungu akho? Kuthekani ngeengxaki zolusu ezingachazwanga? Ezinye zezi mpawu zizibonakaliso zokuba abantu abaninzi basemngciphekweni wokuphuhlisa i-autoimmunity. I-Autoimmunity ichazwa njengokuvuvukala okuzilawulayo kwezicubu zomzimba, okubangelwa ukulahlekelwa ukunyamezela ngamaseli e-dendrik aberrant kunye neempendulo zeeseli ze-B & T. Oku kubangela uphuhliso lwe-immune reactivity ukuya kwii-antigens zomthonyama. Xa izifo ze-autoimmune zenzeka emzimbeni, izifundo zityhila ukuba oku kubangelwa amajoni omzimba ahlasela iimolekyuli ezizimeleyo; iziphazamiso ezininzi zinxulunyaniswa ngamandla nezinto ezininzi ezibeka phambili. 

Izinto ezibangela i-Autoimmunity

Xa kuziwa kwikhonkco phakathi kwezinto ezibangelayo kunye ne-immune system, izifundo zityhila ukuba isizathu kunye nendlela yezifo ezininzi ezizimeleyo ezichaphazela umzimba aziyazi kodwa ukuba izinto ezininzi ezibangela ukuqhubela phambili kwezifo ezizimele zihambelana nemiba eyahlukeneyo engapheliyo. Impendulo ye-immune eguquguqukayo iqukethe amajoni omzimba kunye ne-T lymphocytes esebenzayo edlala indima ephambili kwiimeko zeklinikhi. I iindlela ezininzi ukuba izifo ze-autoimmune zenza emzimbeni ziyaqhubeka kwaye zininzi ngenxa yesiqalo sokuqala senkqubo kunye nokuphazamiseka kwelungu elithile elinokuthi landulela izifo zeklinikhi ngeminyaka emininzi. Ezinye zezinto ezinokubangela i-autoimmunity emzimbeni ziquka:

• Gut
• Endothelial
• ingqondo
• istres
• Iidyobisi
• Infections
• ukutya
• I-Biotoxins (yazalwa)

Yintoni Ukudumba?-Ividiyo

Ngaba ujongene nokudumba malunga namalungu akho kunye nezihlunu? Ngaba ukutya kubonakala kubangela imiba emathunjini akho? Kuthekani ngokuva iintlungu ezibengezelayo zihla ezingalweni okanye emilenzeni yakho? Ezi ziimpawu zokuba umzimba wakho ufumana ukudumba. Le vidiyo ingentla inika ingcaciso ebalaseleyo yokuba yintoni ukudumba kunye nendima yayo emzimbeni. Ukuvutha lukhuselo lwendalo lwamajoni omzimba olubangelwa zizinto ezahlukeneyo ezichaphazela umzimba ngelixa ikhuthaza ukuphiliswa kwindawo echaphazelekayo. Ukudumba kunokuba kuhle okanye kubi; kuxhomekeke kubunzima bokwenzakala komzimba kunye nendawo. Ukuvuvukala kunobudlelwane obuqhelekileyo kunye ne-immune system kwiifom ezibukhali kunye nezingapheliyo. Kwimeko enzima, ukuvuvukala kunokunciphisa ukulimala okanye ukusuleleka kwintsholongwane ukukhuthaza ukuphilisa kwindawo echaphazelekayo ngobushushu, ubomvu, kunye nokuvuvukala. Nangona kunjalo, kwimeko yayo imeko engapheliyo, apho umonakalo unzulu kakhulu, iintsholongwane ezahlukeneyo ezichaphazela izicubu zomzimba zingabangela imiba engapheliyo ehambelana nokuvuvukala. Ngethamsanqa, kukho iindlela zokulawula iimpawu zokuvuvukala ezinxulumene ne-autoimmunity.

Yintoni UBUCHULE?

Umzimba udinga amajoni omzimba ukuze uzikhusele kubahlaseli bangaphandle abangena emzimbeni. Uphando lutyhila ukuba inkqubo yomzimba yokuzikhusela yenza okungakumbi kunokukhusela umzimba; inokukhupha iiseli ezindala, ezonakeleyo emzimbeni kwaye endaweni yazo izitsha. I-immune system iphinda ihlanganise iimpendulo kubahlaseli ngokukwazi kwayo ukwahlula umntu ongenguye. Njengoko bekutshiwo ngaphambili, i-immune system inobudlelwane obubangela ukudumba. Iyakwazi ukuzithoba kwizinto ezibangela ukuba zibandakanyeke kwiimisipha kunye namalungu ahambelana neentlungu. Amajoni omzimba asebenzisa i-acronym DIRT ukulawula nokukhusela umzimba xa kuyimfuneko.

D: Khangela kwaye uzikhusele

I-immune system emzimbeni inendlela echonga izinto ezinokuba yingozi kwimolekyuli ezifana:

• Imiqondiso engaqhelekanga efunyenwe kwiintsholongwane, ukutya, izityalo & nokungunda, imichiza
• Iimpawu zengozi (ii-alarmins) ezifumaneka kwizicubu okanye ezifihliweyo nge-leukocytes okanye i-epithelia

Xa ezi zakhiwo zihlasela umzimba, amajoni omzimba aqala ukubhaqa kwaye abe yindlela yokuzikhusela eya kuthi inyuse iimpendulo ezifanelekileyo kwinqanaba lesisongelo. Nje ukuba isoyikiso sipheliswe, umzimba unokuvelisa ngokutsha iiseli ezisempilweni.

Mna: Ilawulwa Ngaphakathi

Umzimba uneempendulo ze-immune ezilawulwa ngokuqinileyo kwaye zisonjululwe ngokusebenzayo ngeendlela ezininzi zeselula, i-genomic, kunye ne-enzymatic. Eminye yemigaqo ebonelelwa ngamajoni omzimba yile:

• T lymphocytes ezilawulayo
• Abalamli bepro-resolution ephuma kwiLipid
• Ibhalansi ye-Redox: i-Nrf2-ARE isebenze

Nangona kunzima ukulawula amajoni omzimba, ukufumana iindlela zokulawula amajoni omzimba ukuba angaphambani kunye nokufumana ibhalansi elungileyo yesistim somzimba esisempilweni kubalulekile kumzimba osempilweni.

R: Ukubuyisela

Umsebenzi we-immune system kukulungisa nawuphi na umonakalo obangelwe kukwenzakala okanye ukuhlangana okungalunganga okuye kwadlula kuwo umzimba. Xa umzimba ulimala, amajoni omzimba athumela i-cytokines evuthayo kwindawo echaphazelekayo kwaye iqala inkqubo yokuphilisa. Ezinye izakhiwo zeselula ezinceda amajoni omzimba abuyisele umzimba ziquka:

• Phagocytes
• IiFibroblasts
• Iiseli zokuma
• Iiseli ze-Endothelial

Kukho ezinye iindlela zokubuyisela umzimba kunye nokuphucula amajoni omzimba. Ukutya ukutya okunempilo ukomeleza amajoni omzimba, ukwenza umthambo, kunye nokufumana ukhathalelo lwe-chiropractic kunokunceda amajoni omzimba. Kodwa ngaba ukhathalelo lwe-chiropractic alusetyenziselwa umva? Ewe, ukhathalelo lwe-chiropractic lugxile kwinkqubo ye-musculoskeletal, kodwa baxhasa abantu abaninzi ekugcineni impilo yabo kunye nokuphila kakuhle. I-immune system iya kusebenza kumandla ayo onke xa nayiphi na i-spinal misalignments okanye i-subluxation ilungiswa ngokunyanzeliswa komgogodla.

T: Uyanyamezela

I-immune system inceda umzimba ukuba wakhe ukunyamezela kwii-pathogens ezichaphazela umzimba. Umzekelo, i-allergens yokutya. Ngezinto ezininzi zokutya eziqhelekileyo, njengamantongomane, i-gluten, ubisi, intlanzi, kunye namaqanda, umzimba uya kuqala ukwakha ukunyamezela kwezi zinto xa ziziswa ngokukhawuleza. Eminye imida enempilo enikezelwa ngamajoni omzimba emzimbeni ibandakanya:

• Self okanye i-fetus antigens
• Ii-antigens zokusingqongileyo ezingenabungozi
• Iingxaki
• Izityalo kunye nefungi

Ngokwakha ukunyamezelana okunempilo kwezi ntsholongwane, umzimba unethuba eliqinileyo lokwakha ukhuseleko kwi-pathogen. Inganceda amajoni omzimba ukuba abe namandla xa ephinda edibana nezi ntsholongwane.

isiphelo

Ngokubanzi amajoni omzimba ngoyena mkhuseli womzimba kubahlaseli bamanye amazwe. Xa ii-pathogens eziyingozi zingena emzimbeni, amajoni omzimba athumela iicytokines apho abahlaseli bakhoyo kwaye bazisuse. Oku kubangela ukuvuvukala kwindawo echaphazelekayo emzimbeni, kubangela ukudumba kunye nokubomvu kwesikhumba. Xa ezi pathogens zosulela umzimba ngokuhamba kwexesha, amajoni omzimba ahlasela umzimba ngempazamo, ngakumbi amalungu abalulekileyo abangela ukudumba okungapheliyo okuhambelana ne-autoimmunity. I-Autoimmunity liqela leziphazamiso ezibangela ukungasebenzi kakuhle komzimba, okutyhutyha ukudumba okubangela ukuba umzimba ungasebenzi kakuhle. Ngethamsanqa iyanyangeka ngokutya okufanelekileyo, imithambo, kunye nonyango olunokunceda ukuthoba ukudumba kunye nokunceda ukulawula amajoni omzimba abuyele kubuntu bawo.

Ucaphulo

Chaplin, David D. "Amagqabantshintshi ngeMpendulo yoMzimba." Ijenali yeAllergy kunye ne-Clinical Immunology, ILayibrari yeSizwe yaMayeza yase-US, ngoFebruwari 2010, www.ncbi.nlm.nih.gov/pmc/articles/PMC2923430/.

UChen, uLinlin, kunye nabanye. "Iimpendulo ezivuthayo kunye neZifo eziNxulunyaniswe noKudumba kumalungu." Oncotarget, Iijenali zeMpembelelo LLC, nge-14 kaDec. 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5805548/.

Smith, DA, kunye no-DR Germolec. "Intshayelelo kwi-Immunology kunye ne-Autoimmunity." Imiba yezeMpilo, Ilayibrari yeSizwe yaseMelika yoNyango, Okthobha 1999, www.ncbi.nlm.nih.gov/pmc/articles/PMC1566249/.

Vojdani, Aristo. "Unxulumano olunokubakho phakathi kweZixhokonxa zokusiNgqongileyo kunye nokuZikhusela." Izifo eziziThatywayo, Hindawi Publishing Corporation, 12 Feb. 2014, www.ncbi.nlm.nih.gov/pmc/articles/PMC3945069/.

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