Unxibelelwano phakathi koKondla kunye ne-Epigenome

Isondlo sithathwa njengenye yezona zinto ziqondwa kakuhle kokusingqongileyo ezinxulumene notshintsho kwi-epigenome. Izondlo kukutya esikutyayo kuqhubekeka ngenkqubo yemetabolism kwaye iguqulwe ibe mandla. Indlela enye ye-metabolic, nangona kunjalo, inoxanduva lokuvelisa amaqela e-methyl okanye amanqaku asisiseko epigenetic alawula intetho yethu yemfuza. Izakha mzimba eziyimfuneko, ezinje ngeevithamini ze-B, i-SAM-e (S-Adenosyl methionine), kunye ne-folic acid zizinto ezibalulekileyo kule nkqubo ye-methylation. Ukutya okunamaxabiso aphezulu ezi zondlo zibalulekileyo kunokutshintsha ngokukhawuleza ukubonakalisa uhlobo, ingakumbi ngexesha lokuphuhliswa kwangoko. Kwinqaku elilandelayo, siza kuthetha ngonxibelelwano phakathi kwesondlo kunye ne-epigenome.

 

I-Nutrigenomics kunye nezeMpilo

 

Iingcali zononophelo lwezempilo zixoxa ukuba xa kuziwa ekujonganeni nemicimbi yezempilo efana nokuvuvukala kunye nentlungu engapheliyo, ukuqonda indlela izondlo ezichaphazela ngayo impilo yethu yonke ibalulekile. I-genomics yesondlo, okanye i-natigenomics, sisayensi esifunda ulwalamano phakathi kwesondlo, impilo, kunye ne-genome. Abaphandi kwicandelo le-virgenomics bakholelwa ukuba utshintsho kwiimpawu ze-epigenetic zinokunxulumana nemiba eyahlukeneyo yezempilo, kubandakanya ukuvuvukala okanye ukukhula kwezifo ezifana nokukhuluphala, iingxaki zentliziyo, kunye nomhlaza. Izifundo zibonakalise ukuba sinokwazi ukulawula iimpembelelo zezakhamzimba esizidlayo ukuze sitshintshe ukubonakaliswa kwemfuza okuhambelana nemiba eyahlukeneyo yezempilo.

 

Phantse ngaphezulu komntu om-1 kwaba-3 e-United States bafunyaniswa benengxaki yokutya kakhulu okunyusa umngcipheko wemicimbi eyahlukeneyo yezempilo, kubandakanya isifo seswekile kunye nohlobo lweswekile 2, phakathi kwezinye izifo. Izifundo zangaphambili zibonakalise ukuba utshintsho kwiimpawu ze-epigenetic ngexesha lokuphuhliswa kwangoko kunokubeka umntu ekutyebeni kakhulu. Ukongeza, iinguqu kumanqaku epigenetic ziye zaboniswa ukuba zichaphazele umendo we-metabolic onokunyusa umngcipheko wesifo seswekile kunye nohlobo lweswekile 2. Iingcali zononophelo lwempilo kwicandelo lezondgenomics zenze iindlela ezintsha zokufumana ngcono ukulingana ngokuqonda okunesondlo kunye ne-epigenome.

 

Uvavanyo lwe-epigenetic lunokubonelela ngedatha eluncedo kubaqeqeshi bezempilo. Inokubonelela ngolwazi malunga nokuba iindlela ezithile ze-metabolic zichaphazeleka njani zizondlo ezibalulekileyo, ezinje ngeevithamini kunye neeminerals ".

 

Yintoni i-Epigenetics Diet?

 

Igama elithi "ukutya kwe-epigenetics" laqala ukwenziwa nguGqirha Trygve Tollefsbol ngonyaka ka-2011. Kuchazwa ngokwezonyango njengeqela leecomputer, ezinje ngeververatrol kwiidiliya ezibomvu, i-genistein kwii-soya, isothiocyanates eBroccoli, kunye nezinye iintlobo ezininzi ezaziwayo ze ukutya, kubonisiwe ukunceda ukutshintsha amanqaku epigenomic kunye nenkcazo yemfuza. Ngokutsho kwabaphandi, ukutya kwe-epigenetics kunokuthintela ukuqhubela phambili kwamathumba ngokumisela ii-enzymes ezilawula la manqaku epigenomic kunye nentetho ye-gene, kubandakanya ne-methyltransferase ye-DNA, i-histone deacetylases, kunye nee-RNA ezithile ezingezizo iikhowudi. Iindidi zokutya okubandakanyiweyo kwisidlo se-epigenetics ziboniswe kule infographic elandelayo:

 

 

Abaphandi basebenzise ubuchwephesha obutshanje obubonise ukuba iicactical compounds ezininzi zinokuwandisa njani umonakalo kwi-epigenome ebangelwa kukungcoliseka kwendalo. Ngokomzekelo, ukondliwa kokutya kunye nabanikeli be-methyl, njengevithamini B12, i-choline, kunye ne-folate, phakathi kwabanye, kunye ne-isoflavone genistein, inokulawula utshintsho kumanqaku epigenome kunye nentetho ye-gene ebangelwa yi-bisphenol A, ikhemikhali ephazamisa i-hormone . Iivithamini ze-B zinokuthintela kwakhona ukulahleka kwe-methylation ye-DNA ebangelwa kukungcola komoya. Ngokwale maphononongo afanayo, ukondliwa kokutya kunye ne-folic acid kuye kwabonakaliswa ukunceda ukukhusela iziphumo ebezingalunganga zibangelwa zizinyithi ezinzima.

 

Sikholelwa ukuba ukutya ekutyeni kwe-epigenetics kunokusetyenziselwa ukulwa neenguqu kwimbonakalo ye-gene kunye namanqaku epigenomic abangelwa kukungcoliswa kwendalo. Ungcoliseko lwendalo kwiindidi ezahlukeneyo zokutya, ezinjengokubulala izitshabalalisi kwiziqhamo ezinje ngamagqabi kunye namagqabi anamagqabi afana nespinashi, i-bisphenol A kwizitya zeplastiki zokutya neziselo, iidoxin kukutya okunamafutha, iprocyclic enephunga elimnandi lamanzi ahonjelwa xa inyama ityebile okanye itshaya kumaqondo obushushu aphezulu , kunye ne-mercury kwiintlobo ezahlukeneyo zokutya kwaselwandle ezinje nge-king mackerel kunye ne-handfish, zidityaniswe kunye notshintsho kumanqaku epigenomic kunye nentetho ye-gene. Ezo zinto zichaziweyo, ngakumbi ngexesha lophuhliso lwakwangoko, zinokubangela imiba eyahlukeneyo yezempilo.

 

Ngolwazi oluthe kratya malunga nonxibelelwano phakathi kwesondlo kunye ne-epigenome, nceda ubuyekeze eli nqaku:

Isondlo kunye ne-Epigenome

 

Isondlo yenye yezona zinto ziqondakalayo kwezendalo ezinxulumene notshintsho kumanqaku epigenomic kunye nenkcazo yemfuza. Izakha mzimba ezifunekayo ezifumaneka kwiindidi zokutya esizityayo zidityaniswa kwaye ziguqulwe zaba ziimolekyuli ukuze zisetyenziselwe amandla ngumzimba womntu. Indlela enye ye-metabolic inoxanduva lokudala amaqela e-methyl, amanqaku abalulekileyo epigenetic alawula intetho yethu yemfuza kunye namanqaku epigenomic. Izakha mzimba ezibalulekileyo, kubandakanya iivithamini ze-B, i-SAM-e (S-Adenosyl methionine), kunye ne-folic acid zizinto ezibalulekileyo kwi-methylation ye-DNA. Ukutya okutyebileyo kwezi zondlo kubalulekile kunokutshintsha ngokukhawuleza amanqaku epigenetic kunye nenkcazo yemfuzo, ngakumbi ngexesha lokuphuhliswa kwangoko. Ngapha koko, ukongeza iintlobo ezahlukeneyo zokutya ezilungileyo kwi-smoothie kunokuba yindlela ekhawulezayo nelula yokongeza izakha mzimba ekutyeni kwakho. Apha ngezantsi kukho iresiphi ekhawulezayo nelula ye-smoothie yokunceda ukondla iintlobo zakho. - UGqirha Alex Jimenez DC, CCST Insights

 

 

 

 

Yongeza i-Nasturtium kwii-Smoothies zakho

 

Ukongezwa kweentyatyambo ze-nasturtium kunye namagqabi kuyo nayiphi na i-smoothie kunokongeza izakha mzimba. Ezi zityalo zithandekayo kulula ukuzikhulisa kwaye isityalo sonke siyadliwa. Amagqabi eNasturtium aphezulu kwiivithamin C, eyimfuneko ekwenziweni komzimba okukuko, kwaye ane-calcium, potassium, ifosforasi, i-zinc, ubhedu kunye nesinyithi. Ngokwabasebenzi bezempilo, ukukhutshwa kweentyatyambo kunye namagqabi kune-antimicrobial, antifungal, hypotensive, expectorant, and anticancer cancer. I-antioxidants yegadi nasturtium yenzeka ngenxa yomxholo wayo omkhulu wezinto ezinjenge anthocyanins, polyphenols, kunye nevithamin C. Ngenxa yomxholo wayo ocebileyo we-phytochemical kunye nokwenziwa kwezinto ezizodwa, i-nasturtium yegadi inokusetyenziswa kunyango lwemicimbi eyahlukeneyo yezempilo, kubandakanya iingxaki zokuphefumla kunye nokwetyisa. Ungayithethi, iintyatyambo kunye namagqabi zikhangeleka zintle ngokupheleleyo kwii-smoothies.

 

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