Ukungabonwa okanye "uthule" ukuxhamla inokuba negalelo kwezinye iimpawu ezinxulumene nazo Isifo se-Alzheimer, njengokudideka, isifundo esincinci sicebisa.
Ukuxhuzula kwenzeka kwihippocampus - inxalenye yobuchopho ebandakanyekayo ekuhlanganiseni iinkumbulo. Abaphandi bakrokrela ukuba ukunyanga oku kuxhuzula kunokunceda ukulawula i-Alzheimer's okanye ukuyithothisa.
"Nangona ingothusi ukufumana ukungasebenzi kakuhle kuthungelwano lwengqondo kwisifo sika-Alzheimer, inoveli yethu ifumanisa ukuba uthungelwano olubandakanyekayo ekusebenzeni kwenkumbulo lunokuba sisithuthwane buthule lunokukhokelela kumathuba okujolisa ukungasebenzi kakuhle kwamachiza amatsha okanye asele ekho ukunciphisa iimpawu okanye ukuguqula ikhosi. yesi sifo,” watsho uhlolisiso umbhali ophezulu uGqr Andrew Cole.
U-Cole ukhokela i-Massachusetts General Hospital (MGH) Inkonzo ye-Epilepsy.
"Ngoku kufuneka sifunde abantu abaninzi ukuze siqinisekise oku kufunyaniswayo kunye nokuqonda ukuba kuxhaphake kangakanani kwizigulane ze-Alzheimer, nokuba kwenzeka kwezinye izifo ze-neurodeergenerative kunye nendlela esabela ngayo kunyango," watsho esibhedlele.
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Ukuxhaphaka kokuxhuzula kwiiMpawu ze-Alzheimer
Uphononongo lwalubandakanya abafazi ababini kuphela. Bobabini babekwiminyaka yabo engama-60 beneempawu ezinxulumene nesifo sika-Alzheimer. La mabhinqa ayekhe adideke okanye abuze imibuzo efanayo ngokuphindaphindiweyo.
Imifanekiso yobuchopho kunye novavanyo lwe-cerebrospinal fluid lucebise ukuba bane-Alzheimer's, kodwa ukuguquka kweempawu zabasetyhini kwakumangalisa kakhulu kunesiqhelo.
Akukho namnye kwaba basetyhini owayenembali yokuxhuzula. Ngokuqhelekileyo, uvavanyo olubizwa ngokuba yi- EEG eyenziwa entlokweni yentloko inokubona umsebenzi ongaqhelekanga wombane kwingqondo yabantu abaxhuzula. Kodwa, kula mabhinqa mabini, akukho nto ingaqhelekanga ifunyenweyo, abaphandi bathi. Kuba ihippocampus iyinxalenye ephambili yengqondo echatshazelwa sisifo sika-Alzheimer, kwaye ikwangumthombo oqhelekileyo wokuxhuzula kubantu ukuxhamla, abaphandi baphucula kuloo nxalenye yengqondo kwaye benza iimvavanyo ezongezelelweyo.
Ii-Electrodes zabekwa kumacala omabini obuchopho babasetyhini ngokuvuleka okwenzeka ngokwendalo kumazantsi okakayi. Umsebenzi wabo wobuchopho wajongwa iiyure ezingama-24 ukuya kwezingama-72.
Uphononongo lufumanise ukuba abasetyhini banomsebenzi ofana nokuxhuzula kwihippocampus. Elinye ibhinqa lalidla ngokusebenza ngamandla ombane adla ngokunxulunyaniswa nokuxhuzula okungazange kucholwe yi-scalp EEG. Ukuxhuzula kathathu kwenzeka ngexesha lokulala. Akukho nasinye kwezi ziqendu esibangele naziphi na iimpawu ezibonakalayo. Amachiza okulwa nokuxhuzula aphelise umsebenzi ofana nokuxhuzula. Kunyaka olandelayo, eli bhinqa lanesehlo esinye kuphela sokubhideka, esenzeka xa laliphosa iidosi zeyeza lakhe.
Omnye owasetyhini naye wayene-spikes rhoqo kwimisebenzi yombane kwi-hippocampus ngexesha lokulala. Esi sigulana siphinde sanyangwa ngamayeza okunqanda ukuxhuzula kodwa unyango lwayekwa ngenxa yeziphumo ebezingalindelekanga ezinxulumene nemood.
"Iziphumo zethu ziqinisekisile ubukho bokungasebenzi kakubi kwenethiwekhi ye-neuronal echaphazelekayo yi-Alzheimer's disease kwaye yaqinisekisa i-hypothesis yethu yokuba i-epileptic phenomena yinto ebalulekileyo yokuphazamiseka," kusho uCole. Kodwa, wongezelela, kufuneka ufundisiso olungakumbi. Abaphandi banethemba lokuvelisa indlela yokufumanisa oku kuxhuzula kuthe cwaka ngaphandle kokusebenzisa i-electrode ehlasela kancinane ebuchotsheni.
UMTHOMBO: Isibhedlele saseMassachusetts General, ukukhutshwa kweendaba, ngoMeyi 1, 2017
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Iintsikelelo
UDkt Alex Jimenez D.C., I-MSACP, RN*, I-CCST, IFMCP*, I-CIFM*, I-ATN*
email: qeqeshi@elpasofunctionalmedicine.com
Ilayisenisi njengoGqirha weChiropractic (DC) kwi Texas & New Mexico*
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Ubume obubambeneyo: ILayisensi yeeNkcazo ezininzi: Ugunyaziswe Ukuziqhelanisa I-40 States*
UGqr. Alex Jimenez DC, MSACP, RN* CIFM*, IFMCP*, ATN*, CCST
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