Umsebenzi we-Endocrinology: ICortisol neMelatonin isingqi seRadiya

Ngaba uziva:

• Awukwazi ukulala ebusuku?
• Unokuqala kancinci ekuseni?
• Ukudinwa kwemini?
• Ukuvuka ukhathale nasemva kokuba ulale iiyure ezintandathu okanye ngaphezulu?
• Ngaba siphantsi koxinzelelo oluphezulu?

Ukuba ufumana naziphi na kwezi meko, ke kungabakho ngenxa ye-melatonin yakho kunye namanqanaba e-cortisol achaphazela umzimba kunye nesingqisho esijikelezayo.

Kwihlabathi liphela, izigidi zabantu zinengxaki yokulala. EUnited States, kukho malunga I-50-70 yezigidi zabantu abanobuthongo obungalunganga. Xa umntu elele ixesha elingaphantsi kweeyure ezisibhozo, bayadinwa, kwaye iingxaki ezininzi zinokufika kubo, ngakumbi ukuba ubomi babo buxakekile. Ngendlela yokuzixakekisa ngokulala kunye nokungalali kakuhle, kunokubangela ukuba umzimba ube namandla asezantsi ukwenza nawuphi na umsebenzi wenziwe, i-cortisol yoxinzelelo lwe-cortisol iya kuphakanyiswa, kwaye izifo ezifana noxinzelelo lwegazi oluphezulu kunye neswekile kunokubangela iingxaki ezinokubakhona xa zingalulanga. inyangwa.

Kwi-endocrinology esebenzayo, i-melatonin kunye ne-cortisol ziihomoni ezenziwa ngumzimba ngokwendalo. Ihorton ye-cortisol okanye i-hormone yoxinzelelo inceda umzimba ukuba kwimeko "yokulwa okanye yokubaleka", enokuba yinto efanelekileyo kuye nabani na owenza iprojekthi okanye esiya kudliwanondlebe nomsebenzi. Nangona amanqanaba e-cortisol ephezulu, kunokubangela ukuba umzimba ube neengxaki ezifana nokuvuvukala, uxinzelelo lwe-oxidative olungapheliyo, kunye noxinzelelo lwegazi oluphezulu.

Isingqi seMelatonin seRadiyo

Ngehomoni ye-melatonin, le hormone ixelela umzimba xa ilixesha lokulala. Ngamanye amaxesha nangona kunjalo, abantu banobunzima bokulala, kwaye ukuthatha i-melatonin izongezo kunokuwuphumlisa umzimba loo nto yenze ukuba umntu alale. Kuba i-pineal gland ivelisa i-melatonin evela kwingqondo, inokufumaneka nasebusweni, kumongo wamathambo, kunye nesisu ukuze uphumze umzimba kwaye kumenze umntu abalele ngokwemvelo. Abanye zifundo zi bonisa ukuba isingqisho se-circadian ye-pineal gland evelisa i-melatonin. Ngokwenza oku, uphando lubonisa ukuba ulawulo lwe-melatonin:

• inye: yenza ubuthongo kubantu abanengxaki yokulala.
• Mbini: Inqanda umzimba ukuba uvuke ngokwendalo kwi-pacemaker yesekethe.
• Ntathu: tshintsha iiwotshi zebhayoloji yecadiya ukonyusa umthamo wokulala xa umntu efuna ukulala kwangethuba ukuze ufumane izibonelelo zokulala iiyure ezisibhozo.

Xa umntu esebenza emsebenzini we-9 ukuya ku-5, bayakhula ngemizimba yabo kwaye baphumze imizimba yabo emva kosuku olunzima emsebenzini. Izifundo zifunyenwe ukuba iihomoni ze-melatonin kunye ne-cortisol zinceda ekumiseleni iphethini yeeyure ezingama-24 zomsebenzi womzimba kunye nokuphendula ngokumandla. Ngomjikelezo wokuveliswa kwehomoni yomzimba, unokuphazamiseka ukuba umntu uhlala ephaphame kakhulu ebusuku okanye ulale emini. Xa oku kusenzeka, umntu unokufumana ukuphazamiseka okuphazamisayo njengokutshintsha kwemozulu, isiyezi, ukuba nomsindo kunye nokudakumba, kwaye ube nokuphazamiseka kwemetabolism. Ayisiyiyo leya kuphela, kodwa amajoni omzimba kunye nenkqubo yayo ye-endocrine nayo inokonakala ngokunjalo, ibangele ukuba umzimba ube ngumngeneleli kusulelo nakwizifo.

Kufundwe ngaphezulu kwimigqi ye-circadian emzimbeni, njengoko Izifundo zibonisa indlela abantu abasebenza ngayo kutshintsho ebusuku banxulunyaniswe nenani elikhulu leengxaki zempilo ezihlaselayo kwinkqubo yentliziyo kunye nesisu kunye nokuphazamisa inkqubo yemetabolism. Nabani na osebenzise i -hift yasebusuku kufuneka atshintshe ishedyuli yabo yokulala kunye nokuziqhelanisa nohlengahlengiso olukhawulezileyo kucwangciso lwabo lokulala / lokuya emsebenzini ukuze basebenze. Kuba wonke umntu usebenza kwishedyuli yokutshintsha, inokuba noxinzelelo kwaye inokuthi ichaphazele ukusebenza komzimba womsebenzi kunye nokuchaphazela secretion ye-melatonin kunye ne-cortisol.

Iindlela zokuxhasa iCortisol neMelatonin

Kuyamangalisa nangona kunjalo, kukho iindlela zokunciphisa amanqanaba e-cortisol kwaye uqiniseke ukuba amanqanaba e-melatonin asebenza ngokuchanekileyo ukuze umzimba usebenze. Ukuze amanqanaba e-cortisol ahluthwe, umntu kufuneka enze imisebenzi yokucamngca, ufumane indawo ayithandayo, kwaye okona kubaluleke kakhulu, zama ukuzivocavoca ngokunzulu ukuze uphumze umzimba kuxinzelelo olungafunekiyo. Xa usenza imithambo yokuphefumla enzulu, unokunceda umzimba ukuba ukhulule nayiphi na ingxaki ebanjwe ngumntu, kwaye izihlunu emzimbeni ziqale ukuphumla, kwaye igazi liqalisa ukuphuma. Ngamanqanaba e-melatonin, asebenza kunye kunye nesigqi somzimba esijikeleze umzimba kwaye aqinisekise ukuba umzimba uyazi xa ilixesha lokuvuka, ukulala nokutya. I-melatonin hormone inokunceda ukulawula ubushushu bomzimba, ifuthe legazi, kunye namanqanaba amahomoni ukuqinisekisa ukuba asebenza ngokuchanekileyo. Xa kukho amanqanaba aphezulu ezi nkqubo, kunokubangela ukuba umzimba ube nezifo ezingapheliyo kwaye wenzakalise umzimba kwinkqubo.

Uphando lubonisa ukuba iihomoni ze-melatonin zinokubopha kwii-receptors zemithambo emzimbeni, ngaloo ndlela zikhuthaze ukuphumla. Kuba i-melatonin ibopha kwii-receptors ze-neurological, inokunciphisa nomsebenzi we-nerve kunye namanqanaba e-dopamine ukwenza amehlo abe nzima, ngaloo ndlela emenza umntu alale.

isiphelo

Ngomzimba ukukwazi ngokwendalo ukuvelisa amanqanaba e-melatonin kunye ne-cortisol ukuqinisekisa ukuba umzimba awubeki uxinzelelo olugqithisileyo imini yonke. Kuba i-melatonin idibene nomjikelezo womzimba ojikelezayo, umzimba uyazi ukuba kufuneka uhlale nini kwaye ulale. Njengoko wonke umntu eneshedyuli exakekileyo, kubalulekile ukuba uchithe ixesha kwaye uphumle kwaye ube neshedyuli yokulala esempilweni ukuze umzimba ube sempilweni kwaye usebenze. Abanye iimveliso Silapha ukuze uqiniseke ukuba inkqubo ye-endocrine isebenza kakuhle kwaye ixhasa i-adrenal gland kunye neswekile yemetabolism.

Ubungakanani bolwazi lwethu lukhawulelwe kwi-chiropractic, musculoskeletal, kunye nemicimbi yezempilo yovalo okanye amanqaku amayeza asebenzayo, izihloko kunye neengxoxo. Sisebenzisa iiprothokholi zempilo ezisebenzayo ukunyanga ukwenzakala okanye ukuphazamiseka kwenkqubo yemusculoskeletal. Iofisi yethu yenze umzamo oqinisekileyo wokubonelela ngezikhokelo ezixhasayo kwaye ichonge isifundo sophononongo esifanelekileyo okanye izifundo ezixhasa izithuba zethu. Sikwenza iikopi zezifundo zophando ezixhasayo ziya kufumaneka ebhodini okanye kuluntu xa luceliwe. Ukuqhubeka nokuxoxa ngomxholo ongentla, nceda ukhululeke ukubuza uGqirha Alex Jimenez okanye unxibelelane nathi apha 915-850-0900.

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Iingxelo:

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UMonteleone, P, et al. Ubudlelwane beThutyana phakathi kweMelatonin kunye neempendulo zeCortisol kumaXesha asebusuku kuXinzelelo lwaBantu. Psychoneuroendocrinology, I-US National Library of Medicine, i-1992, www.ncbi.nlm.nih.gov/pubmed/1609019.

URaman, uRyan. INDLELA IMELatonin enokukunceda ngayo ukuba ulale kwaye uzive ungcono LwezeMpilo, Imithombo yeendaba yezeMpilo, nge-3 kaSeptemba ngo-2017, www.healthline.com/nutrition/melatonin-and- ukulala.

UZamanian, uZahra, et al. Umda woTshintsho eCortisol naseMelatonin Isangqa seSyadian kwiiGadi zoKhuseleko zeYunivesithi yaseShiraz yezoNyango. Ijenali yaMazwe ngaMazwe yoNyango, IMednow Publications kunye neMedia Pvt Ltd, ngoJulayi 2013, www.ncbi.nlm.nih.gov/pmc/articles/PMC3775223/.

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Ngokwazisa umntu malunga neDyunivesithi yeSizwe yezeNzululwazi yezeMpilo ibonelela ngolwazi kwizizukulwana ezizayo ezifuna ukwenza umohluko emhlabeni. IYunivesithi ibonelela ngeendlela ezahlukeneyo zobungcali bobuchwephesha bokusebenza kunye nokudibanisa amayeza.